Quantitative Analysis Of Neuroanatomy

Author : Julian M L Budd
Publisher : Frontiers Media SA
ISBN 13 : 2889197964
Total Pages : 246 pages
Book Rating : 4.65/5 ( download)

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Download or read book Quantitative analysis of neuroanatomy written by Julian M L Budd and published by Frontiers Media SA. This book was released on 2016-03-22 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt: The true revolution in the age of digital neuroanatomy is the ability to extensively quantify anatomical structures and thus investigate structure-function relationships in great detail. Large-scale projects were recently launched with the aim of providing infrastructure for brain simulations. These projects will increase the need for a precise understanding of brain structure, e.g., through statistical analysis and models. From articles in this Research Topic, we identify three main themes that clearly illustrate how new quantitative approaches are helping advance our understanding of neural structure and function. First, new approaches to reconstruct neurons and circuits from empirical data are aiding neuroanatomical mapping. Second, methods are introduced to improve understanding of the underlying principles of organization. Third, by combining existing knowledge from lower levels of organization, models can be used to make testable predictions about a higher-level organization where knowledge is absent or poor. This latter approach is useful for examining statistical properties of specific network connectivity when current experimental methods have not yet been able to fully reconstruct whole circuits of more than a few hundred neurons.

Author : Stephen M. Evans
Publisher : Oxford University Press, USA
ISBN 13 : 0198505280
Total Pages : 349 pages
Book Rating : 4.80/5 ( download)

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Download or read book Quantitative Methods in Neuroscience written by Stephen M. Evans and published by Oxford University Press, USA. This book was released on 2004 with total page 349 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stereology is a valuable tool for scientists, allowing them to make 3-D reconstructions of the brain from 2-D data. This is a 'cookbook' of stereological methods written especially for neuroscientists, with clear advice about when and when not to use stereology

Author : Michael G. Stewart
Publisher :
ISBN 13 :
Total Pages : 380 pages
Book Rating : 4.46/5 ( download)

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Download or read book Quantitative Methods in Neuroanatomy written by Michael G. Stewart and published by . This book was released on 1992-06-16 with total page 380 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive and up-to-date reference that deals with methods of evaluation of structure and function of the nervous system, both in vitro and in vivo. Part I considers in vitro and ex vivo applications, beginning with the fundamentals of the autoradiographic technique followed by autoradiography and image analysis. Part II discusses several of the latest methods used in evaluating cerebral structure and function in vivo and recent advances in PET, magnetic resonance imaging and biomagnetism. Part III examines applications for quantification of the components of neurons and synapses and considers two- and three-dimensional methods of neuronal reconstruction. Also features the latest advances in stereology.

Author : Luigi F. Agnati
Publisher : Springer Science & Business Media
ISBN 13 : 1461321395
Total Pages : 416 pages
Book Rating : 4.92/5 ( download)

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Download or read book Quantitative Neuroanatomy in Transmitter Research written by Luigi F. Agnati and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Author : Moo K Chung
Publisher : World Scientific
ISBN 13 : 9814472816
Total Pages : 420 pages
Book Rating : 4.14/5 ( download)

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Download or read book Computational Neuroanatomy written by Moo K Chung and published by World Scientific. This book was released on 2012-09-05 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt: Computational neuroanatomy is an emerging field that utilizes various non-invasive brain imaging modalities, such as MRI and DTI, in quantifying the spatiotemporal dynamics of the human brain structures in both normal and clinical populations. This discipline emerged about twenty years ago and has made substantial progress in the past decade. The main goals of this book are to provide an overview of various mathematical, statistical and computational methodologies used in the field to a wide range of researchers and students, and to address important yet technically challenging topics in further detail. Contents:Statistical PreliminaryDeformation-Based MorphometryTensor-Based MorphometryVoxel-Based MorphometryGeometry of Cortical ManifoldsSmoothing on Cortical ManifoldsSurface-Based MorphometryWeighted Fourier RepresentationStructural Brain ConnectivityTopological Data Analysis Readership: Researchers and graduate students in the fields of computational neuroscience and brain imaging, medical image analysis and pattern recognition. Keywords:Computational Neuroanatomy;Brain Image Analysis;NeuroimageKey Features:Includes necessary and very practical mathematical and statistical methodologiesAccessible to a wide range of readers and provides methodological understanding in a manner immediately usable to researchersCovers various topics in great detail without sacrificing readability; it can be used as both a textbook for graduate students and a reference for researchers Reviews: "The book is a comprehensive treatise on computational neuroanatomy — an area that has emerged with the enormous advancements of magnetic resonance imaging (MRI). The book is a solid and evidently needed testimony to the recent developments in the area of computational neuroanatomy. It is a welcome publication, which may appeal to senior graduate students, researchers and practitioners." Zentralblatt MATH

Author : Simon D. Shorvon
Publisher : Springer Science & Business Media
ISBN 13 : 1461525462
Total Pages : 297 pages
Book Rating : 4.62/5 ( download)

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Download or read book Magnetic Resonance Scanning and Epilepsy written by Simon D. Shorvon and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 297 pages. Available in PDF, EPUB and Kindle. Book excerpt: It was only in 1980 that the first recognisable magnetic resonance images of the human brain were published, by Moore and Holland from Nottingham University in England. There then followed a number of clinical trials of brain imaging, the most notable from the Hammersmith Hospital in London using a system designed by EMI, the original manufacturers of the first CT machines. A true revolution in medicine has ensued; in only a few years there are thousands of scanning units, and magnetic resonance imaging (MRI) has assumed a central importance in medical investigation. It is an extraordinary fact that within a few years of development, the esoteric physics of nuclear spin, angular momentum, and magnetic vector precession were harnessed to provide exquisite images of living anatomy; modem science has no greater tribute. That indisputable king of neurology and the oldest of recorded conditions, epilepsy, has not been untouched by the new technology; indeed, it is our view that the introduction of MRI of electroencephalography (EEG) in the late has been as important to epilepsy as was that 1930s. Now, for the first time, the structural and aetiological basis of the condition is susceptible to thorough investigation, and MRI can provide structural detail to parallel the functional detail of EEG. MRI has the same potential as had EEG over 50 years ago, to provide a new level of understanding of the basic mechanisms, the clinical features and the treatment of epilepsy.

Author : Heidi Johansen-Berg
Publisher : Academic Press
ISBN 13 : 0124055095
Total Pages : 627 pages
Book Rating : 4.94/5 ( download)

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Download or read book Diffusion MRI written by Heidi Johansen-Berg and published by Academic Press. This book was released on 2013-11-04 with total page 627 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diffusion MRI remains the most comprehensive reference for understanding this rapidly evolving and powerful technology and is an essential handbook for designing, analyzing, and interpreting diffusion MR experiments. Diffusion imaging provides a unique window on human brain anatomy. This non-invasive technique continues to grow in popularity as a way to study brain pathways that could never before be investigated in vivo. This book covers the fundamental theory of diffusion imaging, discusses its most promising applications to basic and clinical neuroscience, and introduces cutting-edge methodological developments that will shape the field in coming years. Written by leading experts in the field, it places the exciting new results emerging from diffusion imaging in the context of classical anatomical techniques to show where diffusion studies might offer unique insights and where potential limitations lie. Fully revised and updated edition of the first comprehensive reference on a powerful technique in brain imaging Covers all aspects of a diffusion MRI study from acquisition through analysis to interpretation, and from fundamental theory to cutting-edge developments New chapters covering connectomics, advanced diffusion acquisition, artifact removal, and applications to the neonatal brain Provides practical advice on running an experiment Includes discussion of applications in psychiatry, neurology, neurosurgery, and basic neuroscience Full color throughout

Author : Giorgio A. Ascoli
Publisher : Springer Science & Business Media
ISBN 13 : 1592592759
Total Pages : 466 pages
Book Rating : 4.53/5 ( download)

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Download or read book Computational Neuroanatomy written by Giorgio A. Ascoli and published by Springer Science & Business Media. This book was released on 2002-07-01 with total page 466 pages. Available in PDF, EPUB and Kindle. Book excerpt: In Computational Neuroanatomy: Principles and Methods, the path-breaking investigators who founded the field review the principles and key techniques available to begin the creation of anatomically accurate and complete models of the brain. Combining the vast, data-rich field of anatomy with the computational power of novel hardware, software, and computer graphics, these pioneering investigators lead the reader from the subcellular details of dendritic branching and firing to system-level assemblies and models.

Author : Richard T. Robertson
Publisher : Academic Press
ISBN 13 : 1483266400
Total Pages : 462 pages
Book Rating : 4.04/5 ( download)

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Download or read book Neuroanatomical Research Techniques written by Richard T. Robertson and published by Academic Press. This book was released on 2013-10-22 with total page 462 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neuroanatomical Research Techniques discusses developments in major neuroanatomical research techniques. The book is organized into four parts. Part I deals generally with the preparation and study of brain tissue. It includes a chapter on the microscope, discussing optical magnification, limitations of microscopy, and optical contrasting methods. Other chapters summarize basic techniques for tissue preparation and sectioning; present guidelines for a number of standard, but essential, staining procedures; and present sophisticated and contemporary computer techniques that are proving to be invaluable as neuroanatomy evolves from a qualitative to a quantitative discipline. Part II deals with techniques often used for the study of normal tissue. These include the Golgi method, fluorescence histochemistry, techniques for staining single neurons, and the use of the electron microscope. Part III presents techniques for studying intrinsic connections of the nervous system. These include techniques for silver impregnation of degenerating fibers; autoradiographic technique for studying axonal projections; and somatopetal movement of horseradish peroxidase as a tool for studying connections and neuron morphology. Part IV discusses the interpretation of results from neuroanatomical research techniques and presents examples of the applications of neuroanatomical methods to major problems in physiological psychology.

Author : Moo K. Chung
Publisher : World Scientific
ISBN 13 : 9814335436
Total Pages : 424 pages
Book Rating : 4.30/5 ( download)

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Download or read book Computational Neuroanatomy written by Moo K. Chung and published by World Scientific. This book was released on 2013 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt: Computational neuroanatomy is an emerging field that utilizes various non-invasive brain imaging modalities, such as MRI and DTI, in quantifying the spatiotemporal dynamics of the human brain structures in both normal and clinical populations. This discipline emerged about twenty years ago and has made substantial progress in the past decade. The main goals of this book are to provide an overview of various mathematical, statistical and computational methodologies used in the field to a wide range of researchers and students, and to address important yet technically challenging topics in further detail.