Prolactin Disorders

Author : Nicholas A. Tritos
Publisher : Springer
ISBN 13 : 3030118363
Total Pages : 242 pages
Book Rating : 4.65/5 ( download)

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Download or read book Prolactin Disorders written by Nicholas A. Tritos and published by Springer. This book was released on 2019-05-06 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt: This unique book will serve as a valuable resource for clinicians and researchers interested in prolactin physiology and pathophysiology and those who are involved in the care of patients with related disorders, including hyperprolactinemia and prolactin-secreting pituitary adenomas. Timely and up-to-date, it opens with a review of the historical aspects of prolactin research and a discussion of pituitary anatomy and physiology. Several chapters examine basic and translational aspects of prolactin physiology, focusing on recent developments and future directions. The main portion of the book is comprised of chapters presenting the clinical aspects of prolactin excess or deficiency, with particular emphasis placed on prolactin-secreting pituitary adenomas and co-secreting tumors. Concluding chapters address prolactin-secreting pituitary adenomas in special populations – women in the preconception period or during pregnancy, children and adolescents, and men – as well as plurihormonal and aggressive adenomas and carcinomas. Written and edited by experts in the field, Prolactin Disorders will be a ready reference for a diverse array of professionals, from basic scientists to clinical investigators and clinicians from several specialties, including specialists in endocrinology, neurosurgery, radiation oncology and neuro-oncology.

Author : D.F. Horrobin
Publisher : Springer Science & Business Media
ISBN 13 : 9401096953
Total Pages : 245 pages
Book Rating : 4.59/5 ( download)

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Download or read book Prolactin: Physiology and Clinical Significance written by D.F. Horrobin and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 245 pages. Available in PDF, EPUB and Kindle. Book excerpt: I first became interested in prolactin a little over two years ago. I was then working in Nairobi and I knew nothing about the hormone apart from its role in lactation. Professor Mohammed Hyder of the Department of Zoology in the University of Nairobi was interested in the endocrine mechanisms which enable Tilapia fish to adapt to water with a very high electrolyte content. He invited me to a seminar given by Professor Howard Bern which was largely concerned with the role prolactin plays in fluid and electrolyte balance in sub-mammalian vertebrates. This inspired me to begin a programme of research into the roles prolactin plays in man and other animals. Very few physiologists or clinicians seem aware of the multifarious effects of prolactin in mammals. This book therefore aims to give a comprehensive account of the mammalian physiology of prolactin and to make suggestions about its possible role in diseases ranging from cancer to mental illness. The two subjects which have been previously widely covered, the roles of prolactin in lactation and in rat mammary cancer, are presented relatively briefly though with a full list of references. Other subjects are dealt with more extenSively and I hope that many research workers and clinicians may find the book helpful.

Author : George Tolis
Publisher :
ISBN 13 :
Total Pages : 512 pages
Book Rating : 4.06/5 ( download)

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Download or read book Prolactin and Prolactinomas written by George Tolis and published by . This book was released on 1983 with total page 512 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Author : E. Flückiger
Publisher : Springer Science & Business Media
ISBN 13 : 3642817211
Total Pages : 402 pages
Book Rating : 4.12/5 ( download)

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Download or read book Prolactin written by E. Flückiger and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 402 pages. Available in PDF, EPUB and Kindle. Book excerpt: Lactogenic hormone activity was first observed in bovine pituitary extracts by Stricker and Griiter in 1928, working in Bouin's laboratory in Strasbourg. Since that time prolactin has been shown to exist in anterior pituitary extracts of almost all vertebrate species investigated. Although its biology was extensively studied in many mammalian species, the existence of prolactin in the human was generally doubted, despite the positive evidence produced by such researchers as Pasteels. This can partly be explained by the fact that human growth hormone isolated in 1961, is itself a potent lactogen, in contrast to nonprimate growth hormones, and is present in the normal human pituitary in much greater amounts than prolactin. As a result there was a lag of nearly 10 years until prolactin was unanimously accepted as a hormone of the human pituitary, separate from human growth hormone. In 1970 new bioassay techniques permitted the demonstration of prolactin bioactivity in the serum of postpartum women and galactorrhea patients, and chromatographic methods led to the isolation and purification of human prolactin allowing the establishment of a specific radioimmunoassay for this hormone. This opened the road to the understanding of prolactin physiology and pathophysiology in the human, which has revolutionized clinical neuroendocrinology and reproductive endocrinology. Particularly hyperprolactinemia has turned out to be one of the most common endocrine syndromes.

Author : Nelson D. Horseman
Publisher : Springer Science & Business Media
ISBN 13 : 1461516838
Total Pages : 406 pages
Book Rating : 4.35/5 ( download)

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Download or read book Prolactin written by Nelson D. Horseman and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 406 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is an authentic privilege to have the opportunity to assemble and edit a new volume on "Prolactin," the first in several decades to be devoted to this fascinating hormone in all its aspects. The obvious clinical rationale for understanding prolactin (PRL) is the frequent occurrence of prolactinomas, the most common type of pituitary tumor. Fortunately, medical management of prolactinomas can be based on our under standing of the physiology of hypothalamic control of the lactotroph. Armed with this knowledge, therapies for proiactinomas are highly successful and well tolerated. Be cause of the historical and practical importance of knowledge regarding the hypothala mus-Iactotroph axis, the first chapters of this volume are dedicated to reviewing the physiology, development, and cell biology of lactotroph regulation. Chapters focusing on prolactinomas and related clinical issues follow these. PRL is the primary hormone that is responsible for "parental care" in many verte brate species. This reproductive strategy is not unique to mammals, but it has devel oped through evolution to be the central distinguishing feature of the mammalian life cycle. Among the mammals, mice have become the most effective research species in recent years. This can be traced to the development of a wide range of methods for manipulating mouse genetics, and thereby influencing development, physiology and behavior. Mice also provide a profound illustration of the physiological challenges faced in maternity. Female mice undergo a post-partum estrous, and often are both pregnant and lactating simultaneously.

Author : Horst-Dieter Dellmann
Publisher : Springer Science & Business Media
ISBN 13 : 1461566754
Total Pages : 223 pages
Book Rating : 4.55/5 ( download)

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Download or read book Comparative Endocrinology of Prolactin written by Horst-Dieter Dellmann and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 223 pages. Available in PDF, EPUB and Kindle. Book excerpt: The selection of prolactin as the subject of the Midwest Con ference on Endocrinology was not only dictated by the recent ad vances in prolactin research but also by the long tradition in that particular area of Endocrinology in the laboratory of C.W. Turner at the University of Missouri. Therefore, it seems only appropri ate that these proceedings of the Tenth Midwest Conference on En docrinology are dedicated to the memory of this scientist, deceased in August 1975 before completion of this volume, whose pioneer in vestigations have contributed substantially to the advancement of our knowledge in many areas of Endocrinology and who played a major role in the early phases of prolactin research. This volume contains a review of the early studies in Turner's laboratory and the latest results obtained by some of the leading research workers in this area and should be a fitting memory to C.W. Turner. Some of the manuscripts printed here were prepared after the conference was held and include material of more recent origin. Much of the delay in publication was due to the length of time de voted to preparation of these manuscripts. To the other authors and participants, and to Plenum Press, we express our appreciation for their patience and cooperation. We also with to thank Mrs.

Author : Jerrold M. Olefsky
Publisher :
ISBN 13 :
Total Pages : 248 pages
Book Rating : 4.26/5 ( download)

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Download or read book Prolactinomas written by Jerrold M. Olefsky and published by . This book was released on 1986 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Author : Maria Diakonova, PhD
Publisher : Springer
ISBN 13 : 3319121146
Total Pages : 286 pages
Book Rating : 4.47/5 ( download)

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Download or read book Recent Advances in Prolactin Research written by Maria Diakonova, PhD and published by Springer. This book was released on 2014-12-03 with total page 286 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent Advances in Prolactin Research summarizes the current knowledge of prolactin (PRL), PRL receptor, PRL-dependent signaling pathways, the role of PRL in oncogenesis and PRL crosstalk with other oncogenic factors. The chapters are written by experts in these fields and focus on identifying and reviewing timely experimental findings that provide new insights into the expanding role of PRL in the pathophysiology associated with a variety of human conditions. Prolactin is a peptide hormone that is best known for its role in lactation. Prolactin also has an influence on hematopoiesis and angiogenesis, and is involved in the regulation of blood clotting through several pathways. Although PRL was discovered more than 80 years ago, the understanding of PRL signaling and its relationship to various pathologies is still very incomplete. PRL is not only a pituitary hormone with an important role in reproduction, but PRL also acts as a cytokine, modulating a wide variety of physiological processes. For example, data gathered during the last decade have demonstrated that locally produced PRL acts as the autocrine/paracrine factor and plays a contributory role during breast oncogenesis. In fact, the scientific and clinical communities have suggested that the manipulation of the PRL axis may lead to the successful treatment of breast cancer. However, recent work has demonstrated that the role of the PRL axis is much more complex than first envisaged.

Author : H.S. Jacobs
Publisher : Springer Science & Business Media
ISBN 13 : 9401163553
Total Pages : 54 pages
Book Rating : 4.52/5 ( download)

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Download or read book Prolactinomas and Pregnancy written by H.S. Jacobs and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 54 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Author : Ludwig M. Auer
Publisher : Walter de Gruyter GmbH & Co KG
ISBN 13 : 311085385X
Total Pages : 452 pages
Book Rating : 4.58/5 ( download)

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Download or read book Prolactinomas, An interdisciplinary approach written by Ludwig M. Auer and published by Walter de Gruyter GmbH & Co KG. This book was released on 2015-07-24 with total page 452 pages. Available in PDF, EPUB and Kindle. Book excerpt: