Physiology And Physiopathology Of Adipose Tissue

Author : Jean-Philippe Bastard
Publisher : Springer Science & Business Media
ISBN 13 : 2817803434
Total Pages : 432 pages
Book Rating : 4.32/5 ( download)

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Download or read book Physiology and Physiopathology of Adipose Tissue written by Jean-Philippe Bastard and published by Springer Science & Business Media. This book was released on 2012-11-28 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: The scientific advances in the physiology and pathophysiology of adipose tissue over the last two decades have been considerable. Today, the cellular and molecular mechanisms of adipogenesis are well known. In addition, adipose tissue is now recognized as a real endocrine organ that produces hormones such as the leptin acting to regulate food intake and energy balance in the central nervous system, a finding that has completely revolutionized the paradigm of energy homeostasis. Other adipokines have now been described and these molecules are taking on increasing importance in physiology and pathophysiology. Moreover, numerous works have shown that in obesity, but also in cases of lipodystophy, adipose tissue was the site of a local low-grade inflammation that involves immune cells such as macrophages and certain populations of lymphocytes. This new information is an important step in the pathophysiology of both obesity and related metabolic and cardiovascular complications. Finally, it is a unique and original work focusing on adipose tissue, covering biology and pathology by investigating aspects of molecular and cellular biology, general, metabolic, genetic and genomic biochemistry.

Author :
Publisher : BoD – Books on Demand
ISBN 13 : 1838801219
Total Pages : 137 pages
Book Rating : 4.12/5 ( download)

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Download or read book Adipose Tissue written by and published by BoD – Books on Demand. This book was released on 2019-11-06 with total page 137 pages. Available in PDF, EPUB and Kindle. Book excerpt: Adipose tissue, a kind of connective tissue, plays different and significant roles in the human body. Its function includes protection against environmental factors, storage of lipids and triacylglycerol, and the process of thermogenesis. It is also involved in the secretion of highly active biomolecules such as steroid hormones, prostaglandins, as well as proteins called “adipokines.” On the other hand, disturbances in functions of adipose tissue may cause several pathologies such as obesity and insulin resistance. Obesity is a worldwide health problem, whereas diabetes mellitus due to insulin resistance is defined by the World Health Organization as “a progressive worldwide epidemic.” Especially dangerous is visceral accumulation of adipose tissue.This book describes a series of up-to-date topics about physiological and pathological processes in adipose tissue.

Author : Giamila Fantuzzi
Publisher : Springer Science & Business Media
ISBN 13 : 1597453706
Total Pages : 397 pages
Book Rating : 4.07/5 ( download)

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Download or read book Adipose Tissue and Adipokines in Health and Disease written by Giamila Fantuzzi and published by Springer Science & Business Media. This book was released on 2007-11-06 with total page 397 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents a comprehensive survey of adipose tissue, its physiological functions, and its role in disease. The volume spans the entire range of adipose tissue studies, from basic anatomical and physiological research to epidemiology and clinical studies. Groundbreaking recent studies are incorporated into traditional models of adipose tissue properties. A description of the role of macrophages in obesity and metabolism in included.

Author : Ormond A. Macdougald
Publisher : Academic Press
ISBN 13 : 9780128002803
Total Pages : 324 pages
Book Rating : 4.08/5 ( download)

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Download or read book Methods of Adipose Tissue Biology written by Ormond A. Macdougald and published by Academic Press. This book was released on 2014 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a must-have for anyone interested in obesity or the physiology of white or brown adipose tissues. It contains state-of-the-art methods from researchers that are world leaders in this field. Detailed lab protocols range from methods to visualize adipocytes and adipose tissues in humans and experimental models, to convert stem cells into white and brown adipocytes in vitro, to evaluate aspects of adipocyte metabolism, to inducibly knock out genes in adipose tissues, and to evaluate transcriptional control of adipogenesis on a global scale. 1) The study of adipose tissue goes hand in hand with our global effort to understand and reverse the epidemic of obesity and associated medical complications. 2) Contributors include leading researchers who have made tremendous contributions to our ability to investigate white and brown adipose tissues. 3) The wide variety of experimental approaches detailed within this volume: including the evaluation of adipose tissue biology at the molecular, biochemical, cellular, tissue, and organismal levels.

Author : John Field
Publisher :
ISBN 13 :
Total Pages : 536 pages
Book Rating : 4.09/5 ( download)

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Download or read book Handbook of Physiology: Adipose tissue written by John Field and published by . This book was released on 1975 with total page 536 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Author :
Publisher : Academic Press
ISBN 13 : 0128003367
Total Pages : 357 pages
Book Rating : 4.67/5 ( download)

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Download or read book Methods of Adipose Tissue Biology Part B written by and published by Academic Press. This book was released on 2014-02-11 with total page 357 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a must-have for anyone interested in obesity or the physiology of white or brown adipose tissues. It contains state-of-the-art methods from researchers that are world leaders in this field. Detailed lab protocols range from methods to visualize adipocytes and adipose tissues in humans and experimental models, to convert stem cells into white and brown adipocytes in vitro, to evaluate aspects of adipocyte metabolism, to inducibly knock out genes in adipose tissues, and to evaluate transcriptional control of adipogenesis on a global scale. The study of adipose tissue goes hand in hand with our global effort to understand and reverse the epidemic of obesity and associated medical complications Contributors include leading researchers who have made tremendous contributions to our ability to investigate white and brown adipose tissues The wide variety of experimental approaches detailed within this volume: including the evaluation of adipose tissue biology at the molecular, biochemical, cellular, tissue, and organismal levels

Author : Gérard Ailhaud
Publisher : Springer Science & Business Media
ISBN 13 : 1592592317
Total Pages : 332 pages
Book Rating : 4.19/5 ( download)

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Download or read book Adipose Tissue Protocols written by Gérard Ailhaud and published by Springer Science & Business Media. This book was released on 2008-02-03 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt: Adipose tissue is recognized to be exquisitely sensitive to hormone action, and is also now recognized as a secretory and endocrine organ required for reproduction and good health. Adipocytes are “smart” cells able within the tissue to communicate with surrounding cells, but also with various organs, particularly via leptin acting on the central nervous system. Brown adipose tissue (BAT) and white adipose tissue (WAT) are known to be distinct tissues, whereas the heterogeneity of WAT depots is well est- lished. Unfortunately, excess WAT leads to obesity, which is the most common health problem in industrialized countries. Therefore, from both a scientific and a technical point of view, the time has come to create a survey of adipose tissues and their neglected adipocytes. In Adipose Tissue Protocols, I have attempted to gather together chapters from all areas of adipose tissue research—from in vivo to in vitro studies—and to provide methods covering a wide variety of techniques, including the choice of adipose tissue depot and of morphological techniques for the study of BAT and WAT; the isolation, subcellular fractionation, and transfection of adipocytes where the low density of these cells must be taken into account; assays of nutrient and ion fluxes and the metabolic aspects of nutrient uptake; assays of lipid-related enzymes; biopsies and quantification of lipid-related mRNAs; cultures of adipose precursor cells from WAT and BAT of various species, including human tissue; measurements of adipose secretory products; and assessment of WAT metabolism in vivo.

Author : Michael E. Symonds
Publisher : Springer Science & Business Media
ISBN 13 : 1461409659
Total Pages : 414 pages
Book Rating : 4.56/5 ( download)

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Download or read book Adipose Tissue Biology written by Michael E. Symonds and published by Springer Science & Business Media. This book was released on 2011-11-20 with total page 414 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is designed to provide a comprehensive insight into current perspectives and challenges in adipose tissue biology. In Adipose Tissue Biology, scientists and clinicians discuss adipocyte precursors, differentiation and growth, brown and white adipose tissue, gender, inflammation, dietary and genetic determinants of fat mass, together with evolutionary and developmental aspects of adiposity.

Author : Todd Leff
Publisher : John Wiley & Sons
ISBN 13 : 9783527629534
Total Pages : 530 pages
Book Rating : 4.3X/5 ( download)

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Download or read book Adipose Tissue in Health and Disease written by Todd Leff and published by John Wiley & Sons. This book was released on 2010-03-19 with total page 530 pages. Available in PDF, EPUB and Kindle. Book excerpt: This timely and most comprehensive reference available on the topic covers all the different aspects vital in the fight against the global obesity epidemic. Following a look at adipose tissue development and morphology, the authors go on to examine its metabolic and endocrine functions and its role in disease. The final section deals with comparative and evolutionary aspects of the tissue. The result is an essential resource for cell and molecular biologists, physiologists, biochemists, pharmacologists, and those working in the pharmaceutical industry.

Author : Paramjit S. Tappia
Publisher : Springer Nature
ISBN 13 : 3030353583
Total Pages : 348 pages
Book Rating : 4.82/5 ( download)

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Download or read book Pathophysiology of Obesity-Induced Health Complications written by Paramjit S. Tappia and published by Springer Nature. This book was released on 2020-01-17 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: ​According to the World Health Organization, the epidemic of global obesity has nearly tripled since 1975. In 2016, more than 1.9 billion adults were overweight, over 650 million of which were obese. Being overweight and obese has been linked to a number of non-communicable, chronic diseases. Pathophysiology of Obesity-Induced Health Complications is a compilation of review articles dedicated to describe co-morbidities associated with obesity. The wide range that is covered is of significant interest to basic research scientists, clinicians and graduate students who are engaged in studying obesity-induced health complications. Furthermore, this book highlights the potential of novel approaches for the prevention and treatment of obesity and its related illnesses. Nineteen articles in this book are organized in four sections that are designed to provide an overview of obesity-induced health complications. The first section serves as an introductory section on the prevalence, causes, consequences, treatments and preventive approaches for obesity. Section two covers the metabolic disturbances and inflammation due to obesity. The third section is focused on neurological and visceral complications as a consequence of obesity. The final section covers strategies for the prevention of obesity-induced complications. The book illustrates that obesity can result in a diverse range of pathophysiological conditions that adversely affect health.