Philosophy Of Molecular Medicine

Author : Giovanni Boniolo
Publisher : Taylor & Francis
ISBN 13 : 1317378350
Total Pages : 288 pages
Book Rating : 4.58/5 ( download)

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Download or read book Philosophy of Molecular Medicine written by Giovanni Boniolo and published by Taylor & Francis. This book was released on 2016-11-18 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: Philosophy of Molecular Medicine: Foundational Issues in Theory and Practice aims at a systematic investigation of a number of foundational issues in the field of molecular medicine. The volume is organized around four broad modules focusing, respectively, on the following key aspects: What are the nature, scope, and limits of molecular medicine? How does it provide explanations? How does it represent and model phenomena of interest? How does it infer new knowledge from data and experiments? The essays collected here, authored by prominent scientists and philosophers of science, focus on a handful of mainstream topics in the philosophical literature, such as causation, explanation, modeling, and scientific inference. These previously unpublished contributions shed new light on these traditional topics by integrating them with problems, methods, and results from three prominent areas of contemporary biomedical science: basic research, translational and clinical research, and clinical practice.

Author : Giovanni Boniolo
Publisher : Routledge
ISBN 13 : 9781138940680
Total Pages : 270 pages
Book Rating : 4.82/5 ( download)

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Download or read book Philosophy of Molecular Medicine written by Giovanni Boniolo and published by Routledge. This book was released on 2016-10-14 with total page 270 pages. Available in PDF, EPUB and Kindle. Book excerpt: Despite its prominence in scientific research, molecular medicine has not received sufficient attention by the philosophical community. Philosophy of Molecular Medicine: Foundational Issues in Theory and Practiceaims at a systematic investigation of a number of foundational issues in the field of molecular medicine. The volume is organized around four broad modules focusing, respectively, on the following key aspects: What are the nature, scope and limits of molecular medicine? How does it provide explanations? How does it represent and model phenomena of interest? How does it infer new knowledge from data and experiments? The essays collected here, authored by prominent scientists and philosophers of science, focus on a handful of mainstream topics in the philosophical literature, such as causation, explanation, modeling, and scientific inference. These previously unpublished contributions shed new light on these traditional topics by integrating them with problems, methods, and results from three prominent areas of contemporary biomedical science: basic research, translationaland clinical research, and clinical practice.

Author : Jens Kurreck
Publisher : John Wiley & Sons
ISBN 13 : 3527331891
Total Pages : 419 pages
Book Rating : 4.95/5 ( download)

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Download or read book Molecular Medicine written by Jens Kurreck and published by John Wiley & Sons. This book was released on 2016-02-16 with total page 419 pages. Available in PDF, EPUB and Kindle. Book excerpt: Easy to read, yet comprehensive, this is the perfect introduction into the molecular basis of disease and the novel treatment options that have become available. The authors, Jens Kurreck and Cy Stein, have both long-standing teaching experience on the subject, one from a biologist's angle, the other with a medical background. Together, they have produced a modern textbook for courses in Molecular Medicine that incorporates modules from immunology to signaling, from virology to gene therapy, and the latest development in personalized medicine.

Author : Giovanni Boniolo
Publisher : Routledge
ISBN 13 : 1317378342
Total Pages : 288 pages
Book Rating : 4.41/5 ( download)

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Download or read book Philosophy of Molecular Medicine written by Giovanni Boniolo and published by Routledge. This book was released on 2016-11-18 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: Philosophy of Molecular Medicine: Foundational Issues in Theory and Practice aims at a systematic investigation of a number of foundational issues in the field of molecular medicine. The volume is organized around four broad modules focusing, respectively, on the following key aspects: What are the nature, scope, and limits of molecular medicine? How does it provide explanations? How does it represent and model phenomena of interest? How does it infer new knowledge from data and experiments? The essays collected here, authored by prominent scientists and philosophers of science, focus on a handful of mainstream topics in the philosophical literature, such as causation, explanation, modeling, and scientific inference. These previously unpublished contributions shed new light on these traditional topics by integrating them with problems, methods, and results from three prominent areas of contemporary biomedical science: basic research, translational and clinical research, and clinical practice.

Author : Dennis W. Ross
Publisher : Springer Science & Business Media
ISBN 13 : 9780387953724
Total Pages : 180 pages
Book Rating : 4.28/5 ( download)

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Download or read book Introduction to Molecular Medicine written by Dennis W. Ross and published by Springer Science & Business Media. This book was released on 2002-05-17 with total page 180 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presents the discoveries, basic scientific concepts, and sense of excitement that surround the revolution in molecular medicine. The scientific basis of molecular medicine is presented simply and directly, but at a level of technical detail sufficient for the reader to appreciate the power of recombinant DNA technology. The volume is clinically oriented throughout. Annotation copyrighted by Book News, Inc., Portland, OR

Author : Marschall S. Runge
Publisher : Springer Science & Business Media
ISBN 13 : 159259963X
Total Pages : 1299 pages
Book Rating : 4.39/5 ( download)

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Download or read book Principles of Molecular Medicine written by Marschall S. Runge and published by Springer Science & Business Media. This book was released on 2007-11-18 with total page 1299 pages. Available in PDF, EPUB and Kindle. Book excerpt: The concept of molecular medicine dates back to Linus means that there are many new opportunities and challenges Pauling, who in the late 1940s and early 1950s generalized for clinical medicine. One of the effects of the completion of from the ideas that came from the study of the sickle cell the Human Genome Project is the increasing application of hemoglobin molecule. With the first cloning of human genes the fields of molecular biology and genetics to the und- about 1976, molecular genetics took the molecular perspec- standing and management of common diseases. Assimi- tive on disease to the level of DNA. The term molecular tion of the new developments since the first edition has been medicine achieved wide currency in the 1980s with the ably accomplished by Drs. Runge and Patterson with the assignment of this designation to journals, at least one soci- help of their many knowledgeable authors. ety, institutes, and academic divisions of departments of in- As was evident in the first edition, molecular genetics is ternal medicine. Undoubtedly, molecular medicine has been involved in every specialty of medicine. A recurrent theme abetted by the Human Genome Project, which has aided in that edition, perhaps even more striking in the present one, greatly in the molecular characterization of disease.

Author : Mario Bunge
Publisher : World Scientific Publishing Company
ISBN 13 : 9814508969
Total Pages : 288 pages
Book Rating : 4.64/5 ( download)

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Download or read book Medical Philosophy written by Mario Bunge and published by World Scientific Publishing Company. This book was released on 2013-05-30 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the first book that analyzes and systematizes all the general ideas of medicine, in particular the philosophical ones, which are usually tacit. Instead of focusing on one or two points — typically disease and clinical trial — this book examines all the salient aspects of biomedical research and practice: the nature of disease; the logic of diagnosis; the discovery and design of drugs; the design of lab and clinical trials; the crafting of therapies and design of protocols; the moral duties and rights of physicians and patients; the distinctive features of scientific medicine and of medical quackery; the unique combination of basic and translational research; the place of physicians and nurses in society; the task of medical sociology; and the need for universal medical coverage. Health care workers, medicine buffs, and philosophers will find this thought-provoking book highly useful in their line of work and research.

Author : Sahotra Sarkar
Publisher : MIT Press
ISBN 13 : 9780262264730
Total Pages : 426 pages
Book Rating : 4.30/5 ( download)

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Download or read book Molecular Models of Life written by Sahotra Sarkar and published by MIT Press. This book was released on 2007-01-26 with total page 426 pages. Available in PDF, EPUB and Kindle. Book excerpt: Despite the transformation in biological practice and theory brought about by discoveries in molecular biology, until recently philosophy of biology continued to focus on evolutionary biology. When the Human Genome Project got underway in the late 1980s and early 1990s, philosophers of biology—unlike historians and social scientists—had little to add to the debate. In this landmark collection of essays, Sahotra Sarkar broadens the scope of current discussions of the philosophy of biology, viewing molecular biology as a unifying perspective on life that complements that of evolutionary biology. His focus is on molecular biology, but the overriding question behind these papers is what molecular biology contributes to all traditional areas of biological research.Molecular biology—described with some foresight in a 1938 Rockefeller Foundation report as a branch of science in which "delicate modern techniques are being used to investigate ever more minute details"—and its modeling strategies apparently argue in favor of physical reductionism. Sarkar's first three chapters explore reductionism—defending it, but cautioning that reduction to molecular interactions is not necessarily a reduction to genetics (and does not support the claims of either heriditarianism or environmentalism). The next sections of the book discuss function, exploring how functional explanations pose a problem for reductionism; the informational interpretation of biology and how it interacts with reductionism; and the tension between the unifying framework of molecular biology and the received framework of evolutionary theory. The concluding chapter is an essay in the emerging field of developmental evolution, exploring what molecular biology may contribute to the transformation of evolutionary theory as evolutionary theory takes into account morphogenetic development.

Author : Thomas F. Kresina
Publisher : John Wiley & Sons
ISBN 13 : 0471461040
Total Pages : 408 pages
Book Rating : 4.43/5 ( download)

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Download or read book An Introduction to Molecular Medicine and Gene Therapy written by Thomas F. Kresina and published by John Wiley & Sons. This book was released on 2004-03-24 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: An Introduction to Molecular Medicine and Gene Therapy Edited by Thomas F. Kresina, Ph.D. Gene therapy, or the use of genetic manipulation for disease treatment, is derived from advances in genetics, molecular biology, clinical medicine, and human genomics. Molecular medicine, the application of molecular biological techniques to disease treatment and diagnosis, is derived from the development of human organ transplantation, pharmacotherapy, and elucidation of the human genome. An Introduction to Molecular Medicine and Gene Therapy provides a basis for interpreting new clinical and basic research findings in the areas of cloning, gene transfer, and targeting; the applications of genetic medicine to clinical conditions; ethics and governmental regulations; and the burgeoning fields of genomics, biotechnology, and bioinformatics. By dividing the material into three sections - an introduction to basic science, a review of clinical applications, and a discussion of the evolving issues related to gene therapy and molecular medicine-this comprehensive manual describes the basic approaches to the broad range of actual and potential genetic-based therapies. In addition, An Introduction to Molecular Medicine and Gene Therapy: * Covers new frontiers in gene therapy, animal models, vectors, gene targeting, and ethical/legal considerations * Provides organ-based reviews of current studies in gene therapy for monogenetic, multifactoral or polygenic disorders, and infectious diseases * Includes bold-faced terms, key concepts, summaries, and lists of helpful references by subject in each chapter * Contains appendices on commercial implications and a review of the history of gene therapy This textbook offers a clear, concise writing style, drawing upon the expertise of the authors, all renowned researchers in their respective specialties of molecular medicine. Researchers in genetics and molecular medicine will all find An Introduction to Molecular Medicine and Gene Therapy to be an essential guide to the rapidly evolving field of gene therapy and its applications in molecular medicine.

Author : Michel Morange
Publisher : Harvard University Press
ISBN 13 : 9780674001695
Total Pages : 350 pages
Book Rating : 4.99/5 ( download)

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Download or read book A History of Molecular Biology written by Michel Morange and published by Harvard University Press. This book was released on 2000 with total page 350 pages. Available in PDF, EPUB and Kindle. Book excerpt: Every day it seems the media focus on yet another new development in biology--gene therapy, the human genome project, the creation of new varieties of animals and plants through genetic engineering. These possibilities have all emanated from molecular biology. A History of Molecular Biology is a complete but compact account for a general readership of the history of this revolution. Michel Morange, himself a molecular biologist, takes us from the turn-of-the-century convergence of molecular biology's two progenitors, genetics and biochemistry, to the perfection of gene splicing and cloning techniques in the 1980s. Drawing on the important work of American, English, and French historians of science, Morange describes the major discoveries--the double helix, messenger RNA, oncogenes, DNA polymerase--but also explains how and why these breakthroughs took place. The book is enlivened by mini-biographies of the founders of molecular biology: Delbrück, Watson and Crick, Monod and Jacob, Nirenberg. This ambitious history covers the story of the transformation of biology over the last one hundred years; the transformation of disciplines: biochemistry, genetics, embryology, and evolutionary biology; and, finally, the emergence of the biotechnology industry. An important contribution to the history of science, A History of Molecular Biology will also be valued by general readers for its clear explanations of the theory and practice of molecular biology today. Molecular biologists themselves will find Morange's historical perspective critical to an understanding of what is at stake in current biological research.