Perturbing The Organism

Author : Herbert Weiner
Publisher :
ISBN 13 :
Total Pages : 357 pages
Book Rating : 4.56/5 ( download)

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Download or read book Perturbing the Organism written by Herbert Weiner and published by . This book was released on 1992 with total page 357 pages. Available in PDF, EPUB and Kindle. Book excerpt: The concept of stress pervades modern society, yet there exists no generally accepted definition or classification of stressful experience. This authoritative work is the first to analyze critically the entire range of research and theory on stress in animals and humans, from W.B. Cannon and H. Selye's earliest studies in the 1930s up to the present day. Herbert Weiner not only documents the many empirical and conceptual advances of recent years, but also produces a new definition of stress in organismal terms and provides a classification of the various kinds of stressful experience. Because Cannon and Selye's approaches emphasized physiological and medical aspects, the concept of stress soon became inextricably linked to unavoidable and often overwhelming agents such as injury and infection. Overlooked in the early accounts was that all organisms face many additional types of natural challenges and obstacles in their efforts to survive and reproduce: for example, they must fight or escape predators, replenish diminished food supplies, and anticipate, seasonal changes of climate. Weiner's survey of the literature shows that much progress has been made in understanding the effects of exposing animals to these kinds of naturally occurring stressful experiences and their varied outcomes. Under such conditions there appear patterns of integrated behavioral and physiological responses that are exquisitely attuned to the experience. He carefully assesses the research on the ways in which neural circuits and peptidergic mechanisms in the brain generate and integrate these patterns. In addition, he presents new concepts about the perturbation of subsystems, including biological clocks, which may, or may not, lead to disease or ill-health. Perturbing the Organism is the first book to analyze in detail the relevant research in experimental psychology, psychiatry, medicine, endocrinology, immunology, and psychoneuroimmunology to provide a useful, integrative concept of stress--one that is rooted in an understanding of the organism as an interactive communication system composed of many subsystems. It will interest a wide range of clinicians and researchers throughout the medical and behavioral sciences.

Author : Herbert Weiner
Publisher : University of Chicago Press
ISBN 13 : 9780226890418
Total Pages : 388 pages
Book Rating : 4.14/5 ( download)

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Download or read book Perturbing the Organism written by Herbert Weiner and published by University of Chicago Press. This book was released on 1992-06 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: Overlooked in the early accounts was that all organisms face many additional types of natural challenges and obstacles in their efforts to survive and reproduce: for example, they must fight or escape predators, replenish diminished food supplies, and anticipate, seasonal changes of climate. Weiner's survey of the literature shows that much progress has been made in understanding the effects of exposing animals to these kinds of naturally occurring stressful experiences and their varied outcomes. Under such conditions there appear patterns of integrated behavioral and physiological responses that are exquisitely attuned to the experience. He carefully assesses the research on the ways in which neural circuits and peptidergic mechanisms in the brain generate and integrate these patterns. In addition, he presents new concepts about the perturbation of subsystems, including biological clocks, which may, or may not, lead to disease or ill-health.

Author : Frank M. Dattilio
Publisher : Guilford Press
ISBN 13 : 146250874X
Total Pages : 578 pages
Book Rating : 4.47/5 ( download)

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Download or read book Cognitive-Behavioral Strategies in Crisis Intervention written by Frank M. Dattilio and published by Guilford Press. This book was released on 2012-08-22 with total page 578 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book has been replaced by Cognitive-Behavioral Strategies in Crisis Intervention, Fourth Edition, ISBN 978-1-4625-5259-7.

Author : Edda Klipp
Publisher : John Wiley & Sons
ISBN 13 : 352760488X
Total Pages : 486 pages
Book Rating : 4.83/5 ( download)

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Download or read book Systems Biology in Practice written by Edda Klipp and published by John Wiley & Sons. This book was released on 2008-07-15 with total page 486 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presenting the main concepts, this book leads students as well as advanced researchers from different disciplines to an understanding of current ideas in the complex field of comprehensive experimental investigation of biological objects, analysis of data, development of models, simulation, and hypothesis generation. It provides readers with guidance on how a specific complex biological question may be tackled: - How to formulate questions that can be answered - Which experiments to perform - Where to find information in databases and on the Internet - What kinds of models are appropriate - How to use simulation tools - What can be learned from the comparison of experimental data and modeling results - How to make testable predictions. The authors demonstrate how mathematical concepts can illuminate the principles underlying biology at a genetic, molecular, cellular and even organism level, and how to use mathematical tools for analysis and prediction.

Author : Alessandro Minelli
Publisher : Springer Science & Business Media
ISBN 13 : 3642361609
Total Pages : 530 pages
Book Rating : 4.09/5 ( download)

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Download or read book Arthropod Biology and Evolution written by Alessandro Minelli and published by Springer Science & Business Media. This book was released on 2013-04-11 with total page 530 pages. Available in PDF, EPUB and Kindle. Book excerpt: More than two thirds of all living organisms described to date belong to the phylum Arthropoda. But their diversity, as measured in terms of species number, is also accompanied by an amazing disparity in terms of body form, developmental processes, and adaptations to every inhabitable place on Earth, from the deepest marine abysses to the earth surface and the air. The Arthropoda also include one of the most fashionable and extensively studied of all model organisms, the fruit-fly, whose name is not only linked forever to Mendelian and population genetics, but has more recently come back to centre stage as one of the most important and more extensively investigated models in developmental genetics. This approach has completely changed our appreciation of some of the most characteristic traits of arthropods as are the origin and evolution of segments, their regional and individual specialization, and the origin and evolution of the appendages. At approximately the same time as developmental genetics was eventually turning into the major agent in the birth of evolutionary developmental biology (evo-devo), molecular phylogenetics was challenging the traditional views on arthropod phylogeny, including the relationships among the four major groups: insects, crustaceans, myriapods, and chelicerates. In the meantime, palaeontology was revealing an amazing number of extinct forms that on the one side have contributed to a radical revisitation of arthropod phylogeny, but on the other have provided evidence of a previously unexpected disparity of arthropod and arthropod-like forms that often challenge a clear-cut delimitation of the phylum.

Author : Anouk Barberousse
Publisher : Springer Science & Business Media
ISBN 13 : 1402096364
Total Pages : 178 pages
Book Rating : 4.65/5 ( download)

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Download or read book Mapping the Future of Biology written by Anouk Barberousse and published by Springer Science & Business Media. This book was released on 2009-02-26 with total page 178 pages. Available in PDF, EPUB and Kindle. Book excerpt: Carving Nature at its Joints? In order to map the future of biology we need to understand where we are and how we got there. Present day biology is the realization of the famous metaphor of the organism as a bete ˆ machine elaborated by Descartes in Part V of the Discours,a realization far beyond what anyone in the seventeenth century could have im- ined. Until the middle of the nineteenth century that machine was an articulated collection of macroscopic parts, a system of gears and levers moving gasses, solids, and liquids, and causing some parts of the machine to move in response to the force produced by others. Then, in the nineteenth century, two divergent changes occurred in the level at which the living machine came to be investigated. First, with the rise of chemistry and the particulate view of the composition of matter, the forces on macroscopic machine came to be understood as the ma- festation of molecular events, and functional biology became a study of molecular interactions. That is, the machine ceased to be a clock or a water pump and became an articulated network of chemical reactions. Until the ?rst third of the twentieth century this chemical view of life, as re?ected in the development of classical b- chemistry treated the chemistry of biological molecules in much the same way as for any organic chemical reaction, with reaction rates and side products that were the consequence of statistical properties of the concentrations of reactants.

Author : United States. Congress. Joint Committee on Atomic Energy. Subcommittee on Legislation
Publisher :
ISBN 13 :
Total Pages : 1016 pages
Book Rating : 4.6O/5 ( download)

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Download or read book Biology and medicine; training, education, and information; Plowshare; isotopes development; physical research; communities; and AEC administrative programs written by United States. Congress. Joint Committee on Atomic Energy. Subcommittee on Legislation and published by . This book was released on 1964 with total page 1016 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 030909612X
Total Pages : 469 pages
Book Rating : 4.26/5 ( download)

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Download or read book Catalyzing Inquiry at the Interface of Computing and Biology written by National Research Council and published by National Academies Press. This book was released on 2006-01-01 with total page 469 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in computer science and technology and in biology over the last several years have opened up the possibility for computing to help answer fundamental questions in biology and for biology to help with new approaches to computing. Making the most of the research opportunities at the interface of computing and biology requires the active participation of people from both fields. While past attempts have been made in this direction, circumstances today appear to be much more favorable for progress. To help take advantage of these opportunities, this study was requested of the NRC by the National Science Foundation, the Department of Defense, the National Institutes of Health, and the Department of Energy. The report provides the basis for establishing cross-disciplinary collaboration between biology and computing including an analysis of potential impediments and strategies for overcoming them. The report also presents a wealth of examples that should encourage students in the biological sciences to look for ways to enable them to be more effective users of computing in their studies.

Author : A.K. Konopka
Publisher : CRC Press
ISBN 13 : 1420015125
Total Pages : 258 pages
Book Rating : 4.26/5 ( download)

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Download or read book Systems Biology written by A.K. Konopka and published by CRC Press. This book was released on 2006-11-20 with total page 258 pages. Available in PDF, EPUB and Kindle. Book excerpt: With extraordinary clarity,the Systems Biology: Principles, Methods, and Concepts focuses on the technical practical aspects of modeling complex or organic general systems. It also provides in-depth coverage of modeling biochemical, thermodynamic, engineering, and ecological systems. Among other methods and concepts based in logic, computer

Author : Luonan Chen
Publisher : John Wiley & Sons
ISBN 13 : 9780470488058
Total Pages : 416 pages
Book Rating : 4.50/5 ( download)

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Download or read book Biomolecular Networks written by Luonan Chen and published by John Wiley & Sons. This book was released on 2009-06-29 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: Alternative techniques and tools for analyzing biomolecular networks With the recent rapid advances in molecular biology, high-throughput experimental methods have resulted in enormous amounts of data that can be used to study biomolecular networks in living organisms. With this development has come recognition of the fact that a complicated living organism cannot be fully understood by merely analyzing individual components. Rather, it is the interactions of components or biomolecular networks that are ultimately responsible for an organism's form and function. This book addresses the important need for a new set of computational tools to reveal essential biological mechanisms from a systems biology approach. Readers will get comprehensive coverage of analyzing biomolecular networks in cellular systems based on available experimental data with an emphasis on the aspects of network, system, integration, and engineering. Each topic is treated in depth with specific biological problems and novel computational methods: GENE NETWORKS—Transcriptional regulation; reconstruction of gene regulatory networks; and inference of transcriptional regulatory networks PROTEIN INTERACTION NETWORKS—Prediction of protein-protein interactions; topological structure of biomolecular networks; alignment of biomolecular networks; and network-based prediction of protein function METABOLIC NETWORKS AND SIGNALING NETWORKS—Analysis, reconstruction, and applications of metabolic networks; modeling and inference of signaling networks; and other topics and new trends In addition to theoretical results and methods, many computational software tools are referenced and available from the authors' Web sites. Biomolecular Networks is an indispensable reference for researchers and graduate students in bioinformatics, computational biology, systems biology, computer science, and applied mathematics.