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Author : Field, Simon
Publisher : UNESCO Publishing
ISBN 13 : 9231002902
Total Pages : 68 pages
Book Rating : 4.08/5 ( download)
Download or read book Pathways of progression written by Field, Simon and published by UNESCO Publishing. This book was released on 2018-11-12 with total page 68 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Khiry Jones
Publisher :
ISBN 13 : 9780464230519
Total Pages : pages
Book Rating : 4.19/5 ( download)
Download or read book Pathway to Progression written by Khiry Jones and published by . This book was released on 2019-08-21 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: A book that will help you find clarity in the midst of distraction and confusion
Author : Xu Wang
Publisher : Frontiers Media SA
ISBN 13 : 2889747549
Total Pages : 448 pages
Book Rating : 4.42/5 ( download)
Download or read book Inflammatory Tumor Immune Microenvironment: Molecular Mechanisms and Signaling Pathways in Cancer Progression and Metastasis written by Xu Wang and published by Frontiers Media SA. This book was released on 2022-03-25 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Antonella Zannetti
Publisher : Frontiers Media SA
ISBN 13 : 2889714489
Total Pages : 566 pages
Book Rating : 4.83/5 ( download)
Download or read book Tumor Microenvironment: Molecular Mechanisms and Signaling Pathways Involved in Metastatic Progression written by Antonella Zannetti and published by Frontiers Media SA. This book was released on 2021-09-30 with total page 566 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Sujit Nair
Publisher : Frontiers Media SA
ISBN 13 : 2832541852
Total Pages : 180 pages
Book Rating : 4.52/5 ( download)
Download or read book Noncoding RNA in Disease: Diagnosis, Etiology, Progression, Prognosis and Treatment. written by Sujit Nair and published by Frontiers Media SA. This book was released on 2024-01-10 with total page 180 pages. Available in PDF, EPUB and Kindle. Book excerpt: An exciting class of regulatory small noncoding RNAs (ncRNAs) has emerged in recent years that play key role(s) in the etiology/pathogenesis and diagnosis/prognosis of various human diseases including various hematologic and solid cancers, cardiovascular diseases including stroke/atherosclerosis, diabetes, obesity, and metabolic disorders, neuropathies, neurodegeneration including Alzheimer’s Disease, Parkinson’s Disease or Multiple Sclerosis, neurological disorders including epilepsy and muscular dystrophies, liver diseases, pulmonary fibrosis, immune-mediated inflammatory disorders and inflammatory bowel disease, gastritis, autoimmune disorders including arthritis, acromegaly, chronic kidney disease, allergic rhinitis, vitiligo, osteoporosis, obstructive sleep apnea, ocular disease, periodontitis, skeletal muscle atrophy, and parasitic diseases including leishmaniasis, amongst others. These ncRNAs include primarily microRNAs (miRNAs), long noncoding RNAs (lncRNAs), circular RNAs (circRNAs), piwi-interacting RNAs (piRNAs), small nucleolar RNAs (snoRNAs), small interfering RNAs (siRNAs) or exosomal RNAs (exRNAs), etc. that modulate the expression of target genes thus potentially regulating protein expression in normal versus diseased individuals. This Research Topic recognizes the importance of and seeks to explore, ncRNAs in the diagnosis, etiology, progression, prognosis, and treatment of human disease as well as novel biomarker discovery by multi-omics technologies and other methodologies. Indeed, high-throughput technologies employing deep sequencing, proteogenomic, microarrays, and quantitative real-time PCR have begun to shed new light on the architecture of ncRNA landscapes in various diseases and key signal transduction cascades modulated by these ncRNAs in disease pathology. Epigenetic control of gene expression mediated via miRNAs, for instance, has expanded our understanding of transcriptional and post-transcriptional regulation of gene expression by critical ncRNAs in the cellular milieu. Network biology approaches including the construction of relevant ncRNA networks, ncRNA-mRNA networks, and bioinformatics for mining of ncRNAs, are gaining greater relevance in the search for ‘target hubs’ or novel biomarker(s) of disease. Delineation of ncRNA signatures by transcriptomic profiling or RNA-seq, for example, is an important milestone in furthering our knowledge of the repertoire of specific ncRNAs implicated in various diseases. Further, elucidation of the specific steps of the signaling cascades where ncRNAs exert their regulatory actions will augment our understanding of diseases. This will lead to the development of (i) a novel biomarker, or biomarker signature panel, for disease; (ii) ncRNA-based companion diagnostics for diagnosis of disease; (iii) point-of-care testing devices based on ncRNAs; (iv) newer therapeutic agents that target novel biomarkers with specificity, thereby reducing toxicity; (v) ncRNA-based prophylactic approaches of the future; and, (vi) ncRNA-based prognosis of disease.
Author : Alan France
Publisher : Routledge
ISBN 13 : 1134019394
Total Pages : 393 pages
Book Rating : 4.97/5 ( download)
Download or read book Pathways and Crime Prevention written by Alan France and published by Routledge. This book was released on 2013-06-17 with total page 393 pages. Available in PDF, EPUB and Kindle. Book excerpt: Deals with the development of prevention policies and approaches that involve intervention 'early' in the lives of children, young people and their families. This book explores evidence that has been emerging from longitudinal and developmental prevention research.
Author : Pawel Kalinski
Publisher : Springer
ISBN 13 : 331967577X
Total Pages : 271 pages
Book Rating : 4.70/5 ( download)
Download or read book Tumor Immune Microenvironment in Cancer Progression and Cancer Therapy written by Pawel Kalinski and published by Springer. This book was released on 2017-12-22 with total page 271 pages. Available in PDF, EPUB and Kindle. Book excerpt: The tumor microenvironment has become a very important and hot topic in cancer research within the past few years. The tumor microenvironment is defined as the normal cells, molecules, and blood vessels that surround and feed a tumor cell. As many scientists have realized, studying the tumor microenvironment has become critical to moving the field forward, since there are many players in a tumor’s localized and surrounding area, which can significantly change cancer cell behavior. There is a dual relationship wherein the tumor can change its microenvironment and the microenvironment can affect how a tumor grows and spreads. Tumor Microenvironment in Cancer Progression and Cancer Therapy aims to shed light on the mechanisms, factors, and mediators that are involved in the cancer cell environment. Recent studies have demonstrated that in addition to promoting tumor progression and protecting tumor cells from the spontaneous immune-mediated rejection and different forms of cancer therapeutics, tumor microenvironment can also be a target and mediator of both standard and newly-emerging forms of cancer therapeutics. Thus, the dual role of the tumor microenvironment is the integral focus of the volume. The volume highlights the bi-directional interactions between tumor cells and non-malignant tumor component during tumor progression and treatment. It also focuses on the three groups of the reactive tumor component: stromal cells, blood vessels and the infiltrating immune cells. These three groups are discussed under the lens of their role in promoting tumor growth, shielding the tumor from rejection and from standard forms of cancer therapies. They are emerging as targets and mediators of standard and new forms of potential therapy.
Author : Alan Felthous
Publisher : John Wiley & Sons
ISBN 13 : 111915930X
Total Pages : 1250 pages
Book Rating : 4.08/5 ( download)
Download or read book The Wiley International Handbook on Psychopathic Disorders and the Law written by Alan Felthous and published by John Wiley & Sons. This book was released on 2020-11-24 with total page 1250 pages. Available in PDF, EPUB and Kindle. Book excerpt: The economic impact of society's attempts to rehabilitate and contain psychopathically disordered individuals can be enormous. Understanding the nature of these disorders, developing accurate and valid assessment methods, and providing effective treatment and safe management cannot be underestimated. Including contributions from an international panel of experts from Europe, North America, and Asia, this two-volume set offers an in-depth, multidisciplinary look at key aspects of the development and etiology of psychopathic disorders; current methods of intervention, treatment, and management; and how these disorders impact decision-making in civil and criminal law. The most comprehensive major reference work available on psychopathy and the law, The Wiley International Handbook on Psychopathic Disorders and the Law, 2nd Edition: Covers the full history and conceptual development of psychopathic disorders Provides unique and enlightening perspectives on the subject from some of the world’s most well-renowned professionals in the field Looks at the etiology and pathogenesis of psychopathic disorders Examines current methods for the intervention, treatment, and management of ADHD, antisocial behavior, and impulsive aggression Provides in-depth discussions of civil and criminal law issues The Wiley International Handbook on Psychopathic Disorders and the Law, 2nd Edition is a must-have reference for practitioners and academics in clinical psychology, forensic psychology, psychiatry, probation, law, law enforcement, and social work.
Author : Wafik S. El-Deiry
Publisher : Frontiers Media SA
ISBN 13 : 2832534341
Total Pages : 320 pages
Book Rating : 4.42/5 ( download)
Download or read book 365 Days of progress in cancer molecular targets and therapeutics written by Wafik S. El-Deiry and published by Frontiers Media SA. This book was released on 2023-09-26 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Canada. Patent Office
Publisher :
ISBN 13 :
Total Pages : 2200 pages
Book Rating : 4.24/5 ( download)
Download or read book The Canadian Patent Office Record written by Canada. Patent Office and published by . This book was released on 1916 with total page 2200 pages. Available in PDF, EPUB and Kindle. Book excerpt:
