Pathogenesis of Fibrosis

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Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.16/5 ( download)

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Book Synopsis Pathogenesis of Fibrosis by :

Download or read book Pathogenesis of Fibrosis written by and published by . This book was released on 1994 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Lung Epithelial Biology in the Pathogenesis of Pulmonary Disease

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Publisher : Academic Press
ISBN 13 : 0128038810
Total Pages : 276 pages
Book Rating : 4.19/5 ( download)

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Book Synopsis Lung Epithelial Biology in the Pathogenesis of Pulmonary Disease by : Venkataramana K Sidhaye

Download or read book Lung Epithelial Biology in the Pathogenesis of Pulmonary Disease written by Venkataramana K Sidhaye and published by Academic Press. This book was released on 2017-03-09 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: Lung Epithelial Biology in the Pathogenesis of Pulmonary Disease provides a one-stop resource capturing developments in lung epithelial biology related to basic physiology, pathophysiology, and links to human disease. The book provides access to knowledge of molecular and cellular aspects of lung homeostasis and repair, including the molecular basis of lung epithelial intercellular communication and lung epithelial channels and transporters. Also included is coverage of lung epithelial biology as it relates to fluid balance, basic ion/fluid molecular processes, and human disease. Useful to physician and clinical scientists, the contents of this book compile the important and most current findings about the role of epithelial cells in lung disease. Medical and graduate students, postdoctoral and clinical fellows, as well as clinicians interested in the mechanistic basis for lung disease will benefit from the books examination of principles of lung epithelium functions in physiological condition. Provides a single source of information on lung epithelial junctions and transporters Discusses of the role of the epithelium in lung homeostasis and disease Includes capsule summaries of main conclusions as well as highlights of future directions in the field Covers the mechanistic basis for lung disease for a range of audiences

Scleroderma

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Publisher : Springer
ISBN 13 : 3319314076
Total Pages : 743 pages
Book Rating : 4.75/5 ( download)

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Book Synopsis Scleroderma by : John Varga

Download or read book Scleroderma written by John Varga and published by Springer. This book was released on 2016-11-07 with total page 743 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comprised of the authoritative work of international experts, this fully-updated second edition of Scleroderma builds upon the well-regarded approach in the first edition to provide integrated, concise, and up-to-date synthesis of current concepts of pathogenesis and modern approaches to management of systemic sclerosis (scleroderma). With a multidisciplinary approach to comprehensive care, this book is easily accessible for health care professionals in many fields. The new edition includes extensive updated material based on major developments in the field, with new chapters on personalized medicine, cancer complications, global perspectives on scleroderma, and more. It presents a succinct and thoughtful synthesis of current pathomechanistic concepts, providing a valuable reference tool for basic and translational investigators working in the field. Scleroderma: From Pathogenesis to Comprehensive Management serves as an essential, all-inclusive resource for rheumatologists, pulmonologists, cardiologists, gastroenterologists, nephrologists and all those involved in the care of scleroderma patients.

Fibrosis and Inflammation in Tissue Pathophysiology

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Publisher : Frontiers Media SA
ISBN 13 : 2889744973
Total Pages : 369 pages
Book Rating : 4.78/5 ( download)

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Book Synopsis Fibrosis and Inflammation in Tissue Pathophysiology by : Elvira Forte

Download or read book Fibrosis and Inflammation in Tissue Pathophysiology written by Elvira Forte and published by Frontiers Media SA. This book was released on 2022-02-23 with total page 369 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Idiopathic Pulmonary Fibrosis

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Publisher : European Respiratory Society
ISBN 13 : 1849840687
Total Pages : 287 pages
Book Rating : 4.82/5 ( download)

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Book Synopsis Idiopathic Pulmonary Fibrosis by : Ulrich Costabel

Download or read book Idiopathic Pulmonary Fibrosis written by Ulrich Costabel and published by European Respiratory Society. This book was released on 2016-03-01 with total page 287 pages. Available in PDF, EPUB and Kindle. Book excerpt: Idiopathic pulmonary fibrosis (IPF) is a steadily progressive and ultimately fatal disease of unknown origin. Recent years have seen advances in our understanding of IPF and a number of guidelines have been published. But many questions remain unanswered, particularly surrounding probable versus definite IPF. This Monograph aims to discuss the latest achievements in IPF, and covers key diagnostic issues, staging of the disease, complications and comorbidities, treatment, unmet patient needs and perspectives for the future. This book will be of interest to all clinicians and researchers in this area.

Pathogenesis of Fibrosis

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Author :
Publisher : Gustav Fischer
ISBN 13 : 9783437116230
Total Pages : 168 pages
Book Rating : 4.31/5 ( download)

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Book Synopsis Pathogenesis of Fibrosis by : Giulio Gabbiani

Download or read book Pathogenesis of Fibrosis written by Giulio Gabbiani and published by Gustav Fischer. This book was released on 1994 with total page 168 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Renal Fibrosis: Mechanisms and Therapies

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Publisher : Springer
ISBN 13 : 9811388717
Total Pages : 709 pages
Book Rating : 4.12/5 ( download)

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Book Synopsis Renal Fibrosis: Mechanisms and Therapies by : Bi-Cheng Liu

Download or read book Renal Fibrosis: Mechanisms and Therapies written by Bi-Cheng Liu and published by Springer. This book was released on 2019-08-09 with total page 709 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book systemically presents the latest research on renal fibrosis, covering all the major topics in the field, including the possible mechanisms, biomarkers, and strategies for prevention and treatment of chronic kidney disease (CKD). Due to its high prevalence, CKD represents a huge global economic and social burden. Irrespective of the initial causes, CKD progresses to end stage kidney disease (ESKD) due to renal fibrosis, which is characterized by glomerulosclerosis, tubule atrophy and atresia, and the excessive accumulation of extracellular matrix (ECM) in the kidney. Unfortunately, an estimated 1%-2% of the adult population living with CKD will need renal replacement therapy at some point as a result of ESKD. As such, strategies for preventing or slowing CKD progression to ESKD are of utmost importance, and studies aiming to understand the mechanisms of renal fibrosis have been the focus of intensive research. Recently, novel insights into the pathophysiological processes have furthered our understanding of the pathogenesis of renal fibrosis, and more importantly, promoted studies on the early diagnosis and treatment of CKD. This book draws lessons from the extensive, state-of-the-art research in this field, elaborating the new theories and new techniques to offer readers a detailed and comprehensive understanding of renal fibrosis and as well as inspiration for future research directions.

Organ Fibrosis: Pathogenesis, Biomarkers and Therapeutic Targets

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Publisher : Frontiers Media SA
ISBN 13 : 2889719499
Total Pages : 144 pages
Book Rating : 4.95/5 ( download)

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Book Synopsis Organ Fibrosis: Pathogenesis, Biomarkers and Therapeutic Targets by : Henricus A. M. (Rick) Mutsaers

Download or read book Organ Fibrosis: Pathogenesis, Biomarkers and Therapeutic Targets written by Henricus A. M. (Rick) Mutsaers and published by Frontiers Media SA. This book was released on 2022-01-05 with total page 144 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Fibrosis in Disease

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Publisher : Springer
ISBN 13 : 3319981439
Total Pages : 471 pages
Book Rating : 4.37/5 ( download)

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Book Synopsis Fibrosis in Disease by : Monte S. Willis

Download or read book Fibrosis in Disease written by Monte S. Willis and published by Springer. This book was released on 2018-11-10 with total page 471 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fibroproliferative diseases are a broad spectrum of entities from organ-specific involvement (e.g., pulmonary, heart, liver, and kidney fibrosis) to multi-system diseases such as systemic sclerosis and sclerodermatous graft vs. host disease. These diseases also encompass pathophysiologies not readily recognizably related, such as macular degeneration and cancer metastasis. Fibroproliferative diseases are a leading cause of morbidity and mortality and can affect all tissues and organ systems. Remarkable progress in elucidating the pathogenesis of these common diseases with fibrotic components, including the critical roles of myofibroblasts and the molecular mechanisms driving the transcriptional activation involved in the induction of fibrosis. As the importance of these processes is realized in the long-term recovery and treatment of diseases, effective anti-fibrotic therapies targeting the underlying ongoing disease processes are lacking. The complexity of discovering and applying therapies to fibroproliferative disease may be due to the diversity of the systems the pathogenesis of disease itself involves. By nature, fibroproliferative diseases are interdisciplinary, involving multiple cell types (organ-specific epithelial cells), immune cells, endothelial cells, and fibroblasts. Bone marrow, cytokines, and organ-specific pathologies further speckle both the clinical and scientific disciplines in such a way that communication is often limited to the clinical or scientific tribes we live in, despite the greatest access to information known to man available today. Therefore, the primary focus of this text is to bring together authors from a diversity of both clinical, scientific, and therapeutic backgrounds for readers to more fully appreciate that fantastic platform that is available to build upon to lessen the isolation of the clinical and scientific disciplines. With advances in the discovery of pre-clinical therapeutic targets (at least 20+ to date) involving TGF-beta (and other cytokines), transcription factors, and downstream kinases, it’s important to both recognize the broader impact and potential opportunities that exist even today. This book will serve as a state-of-the-art resource for physicians and translational medical researchers alike who are interested in the rapidly evolving field of fibroproliferative diseases. The book will provide new insight into the fundamental mechanisms of classic fibrotic pathophysiologic processes like myocardial infarction, idiopathic pulmonary fibrosis, chronic kidney disease, wound healing, and systemic sclerosis. It will also highlight the many new areas of therapeutic investigation currently underway. Lastly, we will touch upon newly emerging fields investigating the role of fibrosis in macular degeneration and cancer metastasis. The chapters will be written by established experts in their fields, including clinicians (cardiologists, cardiovascular surgeons, pathologists, and general practitioners) and translational biomedical researchers in a wide range of disciplines. However, the material will certainly have a broader audience including medical residents, fellows, and general practitioners as well as M.D. or Ph.D. post-doctoral research fellows. While comprehensive, we'll attempt to present the material in a manner that simplifies the complex pathophysiologic mechanisms that underlie common fibroproliferative diseases while making it appealing to a broad audience.

Cellular and Molecular Mechanisms Underlying the Pathogenesis of Hepatic Fibrosis

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Publisher : MDPI
ISBN 13 : 3039361880
Total Pages : 276 pages
Book Rating : 4.85/5 ( download)

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Book Synopsis Cellular and Molecular Mechanisms Underlying the Pathogenesis of Hepatic Fibrosis by : Ralf Weiskirchen

Download or read book Cellular and Molecular Mechanisms Underlying the Pathogenesis of Hepatic Fibrosis written by Ralf Weiskirchen and published by MDPI. This book was released on 2020-12-29 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: Worldwide, liver fibrosis is a major cause of morbidity and mortality and is associated with a high medical and economic burden. It is the common consequence of chronic liver injury due to various etiologies. During fibrogenesis, there is a progressive substitution of the liver parenchyma by scar tissue. Recent advances in the understanding of the history of liver fibrosis have shown that the pathogenesis is driven by different cell types and a large variety of soluble mediators. At present, scientists working in this field aim to increase basic knowledge, improve diagnostics, and try to translate experimental findings into new treatment modalities. This book includes 12 selected contributions from the Special Issue “Cellular and Molecular Mechanisms Underlying the Pathogenesis of Hepatic Fibrosis” that was published in Cells. These articles summarize current perspectives and findings in hepatic fibrosis research showing how scientists try to use basic scientific research to create new therapies and diagnostics.