Parkinsons Disease Current And Future Therapeutics And Clinical Trials

Author : Néstor Gálvez-Jiménez
Publisher : Cambridge University Press
ISBN 13 : 1107053862
Total Pages : 385 pages
Book Rating : 4.61/5 ( download)

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Download or read book Parkinson's Disease: Current and Future Therapeutics and Clinical Trials written by Néstor Gálvez-Jiménez and published by Cambridge University Press. This book was released on 2016-03-24 with total page 385 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book emphasizes treatment options for Parkinson's disease, providing the necessary clinical and scientific basis for the foundations of solid therapeutics.

Author : Santiago Perez-Lloret
Publisher : Humana
ISBN 13 : 9781071609118
Total Pages : 0 pages
Book Rating : 4.14/5 ( download)

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Download or read book Clinical Trials In Parkinson's Disease written by Santiago Perez-Lloret and published by Humana. This book was released on 2020-08-19 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume looks at major clinical trials for motor and non-motor symptoms in Parkinson’s Disease (PD) and covers important aspects, including trial design, sample selection, and outcome selection. Chapters in this book discuss topics such as toxin-based rodent or genetic models of PD; clinical trials for motor symptoms, L-DOPA related motor complications, and gait disorders; clinical trials for mood disorders, troubled sleep, autonomic dysfunction; and clinical trials for disease modifying therapies. In the Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory or research center. Cutting-edge and authoritative, Clinical Trials in Parkinson’s Disease is a valuable resource for clinicians and researchers who want to enhance their interpretation of results from clinical trials and to design their own high-quality trials.

Author : Sarat Chandra Yenisetti
Publisher : BoD – Books on Demand
ISBN 13 : 1803564881
Total Pages : 252 pages
Book Rating : 4.83/5 ( download)

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Download or read book Parkinson’s Disease - Animal Models, Current Therapies and Clinical Trials written by Sarat Chandra Yenisetti and published by BoD – Books on Demand. This book was released on 2023-12-20 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt: Despite being described about 200 years ago, the pathophysiology of Parkinson’s disease (PD) is not well understood due to its complex etiology and heterogeneity of symptoms and progression. Animal models provide a great opportunity to follow the progression of neurodegeneration and to screen potent therapeutic molecules, knowledge of which can be critical for different levels of clinical trials. Contemporary health technologies are coming in handy to accelerate the pace of developing novel and refined therapeutic strategies for PD. This book, Parkinson’s Disease - Animal Models, Current Therapies and Clinical Trials, provides a comprehensive overview of PD, presenting information on animal models of PD and contemporary therapeutic strategies, health technologies, clinical trials, and their influence on the quality of life of patients with PD.

Author : Jonas H. Ellenberg
Publisher : CRC Press
ISBN 13 : 9780824788230
Total Pages : 600 pages
Book Rating : 4.30/5 ( download)

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Download or read book Etiology of Parkinson's Disease written by Jonas H. Ellenberg and published by CRC Press. This book was released on 1995-03-01 with total page 600 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive reference provides a detailed overview of current concepts regarding the cause of Parkinson's disease-emphasizing the issues involved in the design, implementation, and analysis of epidemiological studies of parkinsonism.

Author :
Publisher : Elsevier
ISBN 13 : 0444642609
Total Pages : 578 pages
Book Rating : 4.08/5 ( download)

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Download or read book Recent Advances in Parkinson's Disease written by and published by Elsevier. This book was released on 2020-04-16 with total page 578 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent Advances in Parkinson ́s Disease Research, Volume 252, represents a follow-up on two previous volumes presented in the Progress in Brain Research series, Volumes 193 and 193, both published in 2010. It contains a collection of overview articles written by leading researchers in Parkinson's, discussing the most important advances made in basic, translational and clinical research. Topics of note in this new release include What can we learn from iPS cell models of PD, What can we learn from animal models of PD?, Molecular basis of selective neuronal vulnerability in PD, Role of innate and adaptive immunity in Parkinson ́s disease, and much more. Covers all key aspects of current research on Parkinson ́s disease Includes topics that range from basic studies on disease models and pathogenic pathways (e.g., protein misfolding, immune and glial mechanisms) to clinical studies on disease features, microbiome, pathophysiology and therapeutic approaches Presents articles authored by world leaders in their respective fields

Author : National Academies of Sciences, Engineering, and Medicine
Publisher : National Academies Press
ISBN 13 : 0309442583
Total Pages : 111 pages
Book Rating : 4.89/5 ( download)

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Download or read book Neuroscience Trials of the Future written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2016-11-07 with total page 111 pages. Available in PDF, EPUB and Kindle. Book excerpt: On March 3-4, 2016, the National Academies of Sciences, Engineering, and Medicine's Forum on Neuroscience and Nervous System Disorders held a workshop in Washington, DC, bringing together key stakeholders to discuss opportunities for improving the integrity, efficiency, and validity of clinical trials for nervous system disorders. Participants in the workshop represented a range of diverse perspectives, including individuals not normally associated with traditional clinical trials. The purpose of this workshop was to generate discussion about not only what is feasible now, but what may be possible with the implementation of cutting-edge technologies in the future.

Author :
Publisher : Elsevier
ISBN 13 : 0444536248
Total Pages : 332 pages
Book Rating : 4.42/5 ( download)

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Download or read book Recent Advances in Parkinsons Disease written by and published by Elsevier. This book was released on 2010-08-20 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt: This first volume starts with an overview on current perspectives in genetic research and on the molecular mechanisms of neurodegeneration. This is followed by a selection of hot topics in pathophysiological research, from molecular studies to system-level investigations based on in vivo electrophysiological recordings and neurocomputational methods. Complete overview of hot topics and approaches to current PD research, from molecules, to brain circuits, to clinical and therapeutic applications. Leading authors review the state-of-the-art in their field of investigation, and provide their views and perspectives for future research. All chapters include comprehensive background information and are written in a clear form that is accessible also to the non-specialist.

Author : Anders Björklund
Publisher : Elsevier Science
ISBN 13 : 9780444537508
Total Pages : 358 pages
Book Rating : 4.03/5 ( download)

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Download or read book Recent Advances in Parkinson's Disease: Translational and clinical research written by Anders Björklund and published by Elsevier Science. This book was released on 2010 with total page 358 pages. Available in PDF, EPUB and Kindle. Book excerpt: This second volume follows on from Part I by reviewing the variety of animal models of PD current available (from drosophila to rodents to non-human primate species) and their specific contributions to PD research. This is followed by comprehensive coverage of functional neuroimaging studies that explore different pathophysiological questions and evaluate treatment outcome in PD patients. Different areas of experimental therapeutics and outstanding challenges to PD treatment are presented in a concluding group of articles. Complete overview of hot topics and approaches to current PD research, from molecules, to brain circuits, to clinical and therapeutic applications Leading authors review the state-of-the-art in their field of investigation, and provide their views and perspectives for future research All chapters include comprehensive background information and are written in a clear form that is also accessible to the non-specialist

Author : Michael Okun, MD
Publisher : Demos Medical Publishing
ISBN 13 : 9781932603811
Total Pages : 249 pages
Book Rating : 4.16/5 ( download)

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Download or read book Ask the Doctor About Parkinson's Disease written by Michael Okun, MD and published by Demos Medical Publishing. This book was released on 2009-09-17 with total page 249 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presents answers to common questions about Parkinson's disease, drawing on the content of the "Ask the Doctor" website column by the National Parkinson Foundation to address concerns related to heredity, treatments, and the future of stem-cell research

Author : J. Eric Ahlskog, ,
Publisher : Oxford University Press, USA
ISBN 13 : 0190231866
Total Pages : 545 pages
Book Rating : 4.66/5 ( download)

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Download or read book The New Parkinson's Disease Treatment Book written by J. Eric Ahlskog, , and published by Oxford University Press, USA. This book was released on 2015 with total page 545 pages. Available in PDF, EPUB and Kindle. Book excerpt: As many as one million Americans, including Michael J. Fox and Muhammad Ali, suffer from Parkinson's Disease. Now, a leader in the fight against Parkinson's, Dr. J. Eric Ahlskog of the Mayo Clinic, has revised and updated his definitive guide for patients and their families. Dr. Ahlskog offers a crystal-clear, nuts-and-bolts approach to the treatment of PD, distilled from more than 30 years of experience as a clinician and researcher. His goal is to educate patients so that they can better team with their doctors to do battle with the disease, streamlining the decision-making process and enhancing their treatment. To do this, Dr. Ahlskog offers a gold mine of information: How do I know if I have PD? What kinds of tests can I take? What medications slow the progress of the disease? What if medications don't help my tremor? What kinds of movement problems may develop later? How can I cope with insomnia and daytime sleepiness, dizziness and depression, memory problems, paranoia, and delusions? Indeed, the book covers virtually every topic related to Parkinson's, from sexual impotence and skin rashes, to the role of nutrition, exercise, and physical therapy. In addition, Dr. Ahlskog discusses brain surgery (though he urges that patients only consider this as a last resort) and such experimental therapies as stem cell transplantation and gene therapy. There are also lists of support and advocacy groups and Web sites that focus on Parkinson's. The ultimate guide to symptoms and treatment, this thoroughly updated Second Edition is the first place patients should turn for reliable, easy-to-grasp information on Parkinson's disease.