Oxetane Synthesis

Author : Navjeet Kaur
Publisher : Elsevier
ISBN 13 : 044318948X
Total Pages : 408 pages
Book Rating : 4.87/5 ( download)

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Download or read book Oxetane Synthesis written by Navjeet Kaur and published by Elsevier. This book was released on 2023-03-22 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: Oxetane Synthesis rings play an important role as versatile motifs both in the overall formation of natural products and in synthetic organic chemistry. Oxetanes are important motifs in pharmaceutical chemistry that can confer improved metabolic and physicochemical properties. These developments continue to enhance the use of oxetanes in medicinal chemistry. Thanks to the growing commercial accessibility of oxetane possessing building blocks, together with improved approaches for the formation, oxetanes are likely to be progressively utilized in medicinal chemistry programs. Oxetanes are becoming valuable as a result of their vast diversity of uses in medicinal chemistry and varying applications. Several procedures have been developed for the formation and ring-opening of oxetanes to give important compounds in agrochemical, medicinal and material sciences. Novel approaches have been developed for the synthesis of oxetanes. These methods depend on both established synthetic approaches and development of many novel approaches for the formation of oxetanes. Highlights methods for the synthesis of oxetanes Includes new developments that enhance the use of oxetanes in medicinal chemistry Covers new approaches recently developed for the synthesis of oxetanes

Author : Maurizio D’Auria
Publisher : Cambridge Scholars Publishing
ISBN 13 : 1527537625
Total Pages : 613 pages
Book Rating : 4.20/5 ( download)

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Download or read book The Paternò-Büchi Reaction written by Maurizio D’Auria and published by Cambridge Scholars Publishing. This book was released on 2019-07-29 with total page 613 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book represents the most complete description of the scientific results obtained on a photochemical experiment described 110 years ago by the Italian scientist Emanuele Paternò. This detailed that the photochemical reaction between a carbonyl compound and an alkene gives a corresponding oxetane. This oxetane ring is present in several naturally occurring compounds and bioactive compounds, and can be obtained with high regio- and stereoselectivity.

Author : Kumar Gadamasetti
Publisher : CRC Press
ISBN 13 : 1420008358
Total Pages : 534 pages
Book Rating : 4.57/5 ( download)

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Download or read book Process Chemistry in the Pharmaceutical Industry, Volume 2 written by Kumar Gadamasetti and published by CRC Press. This book was released on 2007-12-10 with total page 534 pages. Available in PDF, EPUB and Kindle. Book excerpt: As pharmaceutical companies strive to develop safer medicines at a lower cost, they must keep pace with the rapid growth of technology and research methodologies. Defying the misconception of process chemistry as mere scale-up work, Process Chemistry in the Pharmaceutical Industry, Vol. 2: Challenges in an Ever Changing Climate explor

Author : Gianfranco Favi
Publisher : MDPI
ISBN 13 : 3036503404
Total Pages : 372 pages
Book Rating : 4.00/5 ( download)

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Download or read book Modern Strategies for Heterocycle Synthesis written by Gianfranco Favi and published by MDPI. This book was released on 2021-03-17 with total page 372 pages. Available in PDF, EPUB and Kindle. Book excerpt: Heterocycles feature widely in natural products, agrochemicals, pharmaceuticals and dyes, and their synthesis is of great interest to synthetic chemists in both academia and industry. The contributions of recent applications of new methodologies in C–H activation, photoredox chemistry, cross-coupling strategies, borrowing hydrogen catalysis, multicomponent and solvent-free reactions, regio- and stereoselective syntheses, as well as other new, attractive approaches for the construction of heterocyclic scaffolds are of great interest. This Special Issue is dedicated to featuring the latest research that is ongoing in the field of heterocyclic synthesis. It is expected that most submissions will focus on five- and six-membered oxygen and nitrogen-containing heterocycles, but structures incorporating other rings/heteroatoms will also be considered. Original research (communications, full papers and reviews) that discusses innovative methodologies for assembling heterocycles with potential application in materials, catalysis and medicine are therefore welcome.

Author : David C. Blakemore
Publisher : Royal Society of Chemistry
ISBN 13 : 1782627863
Total Pages : 536 pages
Book Rating : 4.69/5 ( download)

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Download or read book Synthetic Methods in Drug Discovery written by David C. Blakemore and published by Royal Society of Chemistry. This book was released on 2016 with total page 536 pages. Available in PDF, EPUB and Kindle. Book excerpt: The number of available synthetic methods can be overwhelming. In order to create novel motifs and templates which confer new and potentially valuable drug-like properties, it is important to know which synthetic methodologies will give the best results. Similarly, which methodologies are used to progress potential drug candidates from leads through the development process? What are the current industrial research problems and how can they be resolved in an industrial setting? This book highlights key methods that have real impact in drug discovery and facilitate delivery of drug molecules. Synthetic Methods in Drug Discovery Volume 1 focuses on the hugely important area of transition metal mediated methods used in industry. Current methods of importance such as the Suzuki-Miyaura coupling, Buchwald-Hartwig couplings and CH activation are discussed. In addition, exciting emerging areas such as decarboxylative coupling, and the uses of iron and nickel in coupling reactions are also covered. This book provides both academic and industrial perspectives on some key reactions giving the reader an excellent overview of the techniques used in modern synthesis. Reaction types are conveniently framed in the context of their value to industry and the challenges and limitations of methodologies are discussed with relevant illustrative examples. Edited and authored by leading scientists from both academia and industry, this book will be a valuable reference for all chemists involved in drug discovery as well as postgraduate students in medicinal chemistry.

Author : Angelo Albini
Publisher : John Wiley & Sons
ISBN 13 : 3527323910
Total Pages : 498 pages
Book Rating : 4.13/5 ( download)

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Download or read book Handbook of Synthetic Photochemistry written by Angelo Albini and published by John Wiley & Sons. This book was released on 2010-02-01 with total page 498 pages. Available in PDF, EPUB and Kindle. Book excerpt: Unique in its focus on preparative impact rather than mechanistic details, this handbook provides an overview of photochemical reactions classed according to the structural feature that is built in the photochemical step, so as to facilitate use by synthetic chemists unfamiliar with this topic. An introductory section covers practical questions on how to run a photochemical reaction, while all classes of the most important photocatalytic reactions are also included. Perfect for organic synthetic chemists in academia and industry.

Author : Hans R. Kricheldorf
Publisher : CRC Press
ISBN 13 : 9780824785147
Total Pages : 976 pages
Book Rating : 4.42/5 ( download)

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Download or read book Handbook of Polymer Synthesis written by Hans R. Kricheldorf and published by CRC Press. This book was released on 1991-12-23 with total page 976 pages. Available in PDF, EPUB and Kindle. Book excerpt: A relatively compact, but nonetheless comprehensive, review of the most important preparative methods for the synthesis and chemical modification of polymers. The contents are subdivided according to chemical structure of the polymer backbone. Complementary emphasis is on special properties and appl

Author : L.A. Paquette
Publisher : Elsevier
ISBN 13 : 0080912486
Total Pages : 1360 pages
Book Rating : 4.86/5 ( download)

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Download or read book Combining C-C ?-Bonds written by L.A. Paquette and published by Elsevier. This book was released on 1992-09-08 with total page 1360 pages. Available in PDF, EPUB and Kindle. Book excerpt: The guiding principle underlying the subject matter specifically compiled in Volume 5 has been to make available to the organic chemical community a sourcebook comprehensively covering all the important &pgr;-bond-dependent transformations. Thermal, photochemical, and metal-catalyzed cycloadditions of every major type are expertly detailed by the most knowledgeable researchers in these areas. The synthetically useful electrocyclic and sigmatropic processes where alkenic centers are intimately involved in the structural change are similarly canvassed in compact detail. With added attention given to ene reactions, small-ring rearrangements, and related transition metal-associated reactions, coverage has been achieved of the full range of organic transformations directly involving the rebonding of alkenic centers. As a consequence, this volume should serve as the comprehensive sourcebook of the field for the next decade and beyond.

Author : William M. Horspool
Publisher : CRC Press
ISBN 13 : 020349590X
Total Pages : 2898 pages
Book Rating : 4.02/5 ( download)

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Download or read book CRC Handbook of Organic Photochemistry and Photobiology, Volumes 1 & 2 written by William M. Horspool and published by CRC Press. This book was released on 2003-09-29 with total page 2898 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second edition of this best-selling handbook is bigger, more comprehensive, and now completely current. In addition to thorough updates to the discussions featured in the first edition, this edition includes 66 new chapters that reflect recent developments, new applications, and emerging areas of interest. Within the handbook's 145 critically r

Author : Michael Harmata
Publisher : Academic Press
ISBN 13 : 0124058558
Total Pages : 345 pages
Book Rating : 4.52/5 ( download)

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Download or read book Strategies and Tactics in Organic Synthesis written by Michael Harmata and published by Academic Press. This book was released on 2013-07-29 with total page 345 pages. Available in PDF, EPUB and Kindle. Book excerpt: A classic in the area of organic synthesis, Strategies and Tactics in Organic Synthesis provides a forum for investigators to discuss their approach to the science and art of organic synthesis. Rather than a simple presentation of data or a secondhand analysis, we are given stories that vividly demonstrate the power of the human endeavor known as organic synthesis and the creativity and tenacity of its practitioners. Firsthand accounts of each project tell of the excitement of conception, the frustration of failure and the joy experienced when either rational thought or good fortune gives rise to the successful completion of a project. This book series shows how synthesis is really done, and we are educated, challenged and inspired by these accounts, which portray the idea that triumphs do not come without challenges. We also learn that we can meet challenges to further advance the science and art of organic synthesis, driving it forward to meet the demands of society, in discovering new reactions, creating new designs and building molecules with atom and step economies that provide solutions through function to create a better world. Presents state-of-the-art developments in organic synthesis Provides insight and offers new perspective to problem-solving Written by leading experts in the field