Osseointegration Of Orthopaedic Implants

Author : Amirhossein Goharian
Publisher : Academic Press
ISBN 13 : 0128133953
Total Pages : 214 pages
Book Rating : 4.58/5 ( download)

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Download or read book Osseointegration of Orthopaedic Implants written by Amirhossein Goharian and published by Academic Press. This book was released on 2019-03-16 with total page 214 pages. Available in PDF, EPUB and Kindle. Book excerpt: Osseointegration of Orthopaedic Implants helps product developers at orthopedic implant manufacturers enhance the effectiveness of orthopedic implants and reduce complications, particularly in patients with osteoporotic bones. The book's expert contributors provide cutting-edge information on the latest technologies and advances available. Biomaterial researchers can use the book for basic data in the further development of orthopedic implant materials with better osseointegration. Biomechanical researchers can review related challenges and concepts of osseointegration for use in the development of implants. The book is suitable for readers from academia and industry, bridging the knowledge gap between academic based researchers, industrial based engineers, and clinical based surgeons. Reviews and discusses all aspects of orthopedic implant osseointegration Provides conceptual implants for bone fracture fixation and joint replacement Offers novel ideas for the development of orthopedic implants with superior osseointegration

Author : Amirhossein Goharian
Publisher : Academic Press
ISBN 13 : 9780128133842
Total Pages : 0 pages
Book Rating : 4.48/5 ( download)

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Download or read book Osseointegration of Orthopaedic Implants written by Amirhossein Goharian and published by Academic Press. This book was released on 2019-03-19 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Osseointegration of Orthopaedic Implants helps product developers at orthopedic implant manufacturers enhance the effectiveness of orthopedic implants and reduce complications, particularly in patients with osteoporotic bones. The book's expert contributors provide cutting-edge information on the latest technologies and advances available. Biomaterial researchers can use the book for basic data in the further development of orthopedic implant materials with better osseointegration. Biomechanical researchers can review related challenges and concepts of osseointegration for use in the development of implants. The book is suitable for readers from academia and industry, bridging the knowledge gap between academic based researchers, industrial based engineers, and clinical based surgeons.

Author : Amirhossein Goharian
Publisher : Academic Press
ISBN 13 : 0128189312
Total Pages : 252 pages
Book Rating : 4.13/5 ( download)

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Download or read book Osseoconductive Surface Engineering for Orthopedic Implants written by Amirhossein Goharian and published by Academic Press. This book was released on 2021-01-26 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt: Osseoconductive Surface Engineering for Orthopedic Implants provides a comprehensive overview of the state of the art of osseointegration based on surface-mediated engineering. It offers a practical approach to the design and development of implant surface engineering, by reviewing and discussing the usability and efficacy of each processing technique. The reader can learn about the variety, characteristics, advantages, challenges, and optimum parameters for each process—enabling targeted selection of coatings and technologies to enhance long-term implant–bone integration. Practical and engineering notions in the field of osseoconductive surface engineering are reviewed and discussed using scientific principles and concepts. Engineering cases are analyzed in depth giving a thorough exploration and description of the engineering and scientific concepts for all osseoconductive surface engineering processes. Chapters integrate topics and are organised in such a way as to build on themes and practice.

Author : Jan Sieniawski
Publisher : BoD – Books on Demand
ISBN 13 : 9535111108
Total Pages : 160 pages
Book Rating : 4.08/5 ( download)

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Download or read book Titanium Alloys written by Jan Sieniawski and published by BoD – Books on Demand. This book was released on 2013-05-15 with total page 160 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book contains six chapters and covers topics dealing with biomedical applications of titanium alloys, surface treatment, relationships between microstructure and mechanical and technological properties, and the effect of radiation on the structure of the titanium alloys.

Author : Bingyun Li
Publisher : Springer Nature
ISBN 13 : 3030344711
Total Pages : 808 pages
Book Rating : 4.19/5 ( download)

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Download or read book Racing for the Surface written by Bingyun Li and published by Springer Nature. This book was released on 2020-02-28 with total page 808 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers the key basics of tissue engineering as well as the latest advances in the integration of both antimicrobial and osteoinductive properties. Topics covered include osteoconductive and osteoinductive biomaterials (calcium phosphate, bone morphogenetic protein, peptides, antibodies, bioactive glasses, nanomaterials, etc.) and scaffolds. Research integrating both antimicrobial/biofilm-inhibiting and osteoinductive/osteoconductive properties and their co-delivery is detailed and their roles in clinical success are discussed. Combined with its companion volume, Racing for the Surface: Antimicrobial and Interface Tissue Engineering, this book bridges the gap between infection and tissue engineering, and is an ideal book for academic researchers, clinicians, industrial engineers and scientists, governmental representatives in national laboratories, and advanced undergraduate students and post-doctoral fellows who are interested in tissue engineering and regeneration, infection, and biomaterials and devices.

Author : Amirhossein Goharian
Publisher : Academic Press
ISBN 13 : 0323954111
Total Pages : 326 pages
Book Rating : 4.12/5 ( download)

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Download or read book Interactions of Bone with Orthopedic Implants and Possible Failures written by Amirhossein Goharian and published by Academic Press. This book was released on 2022-07-20 with total page 326 pages. Available in PDF, EPUB and Kindle. Book excerpt: Interactions of Bone with Orthopedic Implants and Possible Failures focuses on the mechanical and biological issues that may cause failure of the implant-bone construct. The book provides discussions on the effects of the design, process, surface and other engineering parameters of implants and their interaction with bone tissue. For implant designers, it is highly crucial to know the final effects of what they are designing or aiming to design, along with performance parameters. It is also crucial for orthopedic surgeons to be familiar with the background of the design and process parameters of the implant they will insert in a patient’s body. With the understanding brought forth in this book, surgeons can have better implant options and implant designers can create and develop new implant designs. This book can also help biomechanical and mechanical engineers who are normally dealing with testing and analysis of orthopedic implants examine the biomechanical behavior of the implants and their interaction with bone tissue. Explains interactions, along with possible complications of trauma, joint and spinal implants, and failures of the implant and bone tissue Focuses on issues such as bone loss, defects and resorption at the bone and implant interface Includes case studies of implant failures and discusses the mechanical and biological reasons that would cause failure of bone and implant integration

Author : Gunther Heimke
Publisher : CRC Press
ISBN 13 : 9780849359583
Total Pages : 212 pages
Book Rating : 4.89/5 ( download)

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Download or read book Osseo-Integrated Implants written by Gunther Heimke and published by CRC Press. This book was released on 1990-07-03 with total page 212 pages. Available in PDF, EPUB and Kindle. Book excerpt: The focus of this two-volume work is osseo integration. It discusses the use of glue to attach bony tissue as well as the use of the absence of biochemical interactions between some oxide ceramics (particularly pure A1203 ceramic) and the adjacent tissue. This book also demonstrates the possibility of controlling the interface remodelling by the stresses and strains created by the insertion of the implant. Written in a concise, easy-to-read format, this text covers the use of implants in orthopedics, maxillo-facial surgery, and dentistry. All those involved with bioengineering, orthopedics, maxillo-facial surgery, dentistry, and biomechanics will find this reference to be of particular interest.

Author : Lindsay Ann Bonsignore
Publisher :
ISBN 13 :
Total Pages : 150 pages
Book Rating : 4.44/5 ( download)

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Download or read book Surface Contaminants Inhibit the Osseointegration of Orthopaedic Implants written by Lindsay Ann Bonsignore and published by . This book was released on 2012 with total page 150 pages. Available in PDF, EPUB and Kindle. Book excerpt: The most important factor contributing to short-term and long-term success of cementless total joint arthroplasties is osseointegration. Osseointegration is the process by which a direct structural and functional connection between living bone and the surface of an implant is made. Surface contaminants may remain on orthopaedic implants after sterilization procedures and impair osseointegration. For example, specific lots of hip replacement Sulzer Inter-OPTM acetabular shells that were associated with impaired osseointegration and early failure rates were found to be contaminated with both bacterial debris and machine oil residues. However, few osseointegration studies have focused on surface contaminants and their effect on implant integration is unknown. Therefore, we developed a novel murine model that provides quantitative and reproducible measurements of osseointegration to study the effect of surface contaminants. We found that a rigorous cleaning procedure significantly enhances osseointegration compared to implants that were autoclaved. The most likely interpretation of these results is that surface contaminants on the autoclaved implants inhibit osseointegration. Using our murine model, we also found that Gram-negative bacterial derived LPS or machine oil residues on implants inhibit osseointegration. Ultrapure LPS adherent to titanium alloy discs had no detectable effect on early stages of MC3T3-E1 osteogenesis in vitro such as attachment, spreading or growth but inhibited later stages of osteogenic differentiation and mineralization. In contrast, machine oil on titanium alloy discs inhibited osteoblast attachment, spreading, growth, differentiation and mineralization in vitro. These results demonstrate that both adherent LPS and machine oil can significantly impair osseointegration through direct effects on osteoblasts; however, they do so by inhibiting distinct steps in the process. The presence of both LPS and machine oil could lead to synergistic impairment of osseointegration, which may account for the impaired osseointegration in the failed lots of Sulzer Inter-OPTM implants. These results highlight bacterial debris and machine oil as types of surface contaminants that can impair the osseointegration of orthopaedic implants. In addition, these results justify the need for the development of better detection and removal techniques for contaminants on orthopaedic implants.

Author : Theofilos Karachalios
Publisher : Springer Science & Business Media
ISBN 13 : 1447154096
Total Pages : 342 pages
Book Rating : 4.99/5 ( download)

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Download or read book Bone-Implant Interface in Orthopedic Surgery written by Theofilos Karachalios and published by Springer Science & Business Media. This book was released on 2013-11-19 with total page 342 pages. Available in PDF, EPUB and Kindle. Book excerpt: Total joint arthroplasty is an effective surgical procedure for end-stage osteoarthritis of major joints with satisfactory long term clinical outcome. A large and growing number of arthroplasties are performed annually worldwide and a great number of orthopaedic surgeons are practicing arthroplasty surgery as their main surgical activity. The biological behavior of the bone-implant interface is crucial for the long term survival of the artificial joint. All factors which have a positive or negative effect on the interface are of great interest for those practicing arthroplasty surgery. Basic scientists and the industry are continuously searching for new implant fixation mechanisms and improved materials. There is an accumulation of a great amount of basic science data (both biological, material and mechanical) related to the incorporation or loosening of the bone-implant interface. However, basic science data does not always translate to satisfactory clinical application, and orthopaedic practitioners often wonder which piece of information is clinically useful. A further problem is that basic scientists often speak their own scientific language and may not fully appreciate common clinical practice needs. In this textbook the biological and mechanical mechanisms of implant incorporation and loosening will be presented. All new data concerning materials and methods for incorporation enhancement will be critically analyzed. Data useful for clinical application will be stressed. Orthopaedic Surgeons will find information which will improve their clinical practice and basic scientists will be helped to understand and appreciate clinical needs.

Author : John Older
Publisher : Springer Science & Business Media
ISBN 13 : 1447118111
Total Pages : 343 pages
Book Rating : 4.14/5 ( download)

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Download or read book Implant Bone Interface written by John Older and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 343 pages. Available in PDF, EPUB and Kindle. Book excerpt: An update on current knowledge is given for surgeons and researchers involved in implant surgery and the development of implant arthroplasty. The contributions come from a distinguished international faculty of orthopaedic surgeons, biologists and engineers. They examine the junctional tissues between an implant and the bone in joint replacement surgery. The factors that influence junctional tissues and so affect the life-span of the implant are thoroughly discussed. These include: detailed data on the microscopy of the junctional tissues, the mechanical properties of cement, and the architecture of bone and implant design. The discussions following each contribution give meaningful insight into background information and the controversial aspects of surgical implants.