Origin And Evolution Of Telomeres

Author : Jozef Nosek
Publisher : CRC Press
ISBN 13 : 1498713491
Total Pages : 194 pages
Book Rating : 4.98/5 ( download)

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Download or read book Origin and Evolution of Telomeres written by Jozef Nosek and published by CRC Press. This book was released on 2008-05-26 with total page 194 pages. Available in PDF, EPUB and Kindle. Book excerpt: Linear chromosomes represent an evolutionary innovation associated with the origin of eukaryotic cells. This book describes how linear chromosomes and primordial pathways for maintaining their terminal structures, telomeres, emerged in early eukaryotes.Telomeres, derived from the Greek meaning terminal part, were first described by Hermann Muller i

Author : Jozef Nosek
Publisher :
ISBN 13 : 9780387790718
Total Pages : pages
Book Rating : 4.13/5 ( download)

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Download or read book Origin and Evolution of Telomeres written by Jozef Nosek and published by . This book was released on 2008-07 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Author : Titia De Lange
Publisher :
ISBN 13 :
Total Pages : 598 pages
Book Rating : 4.06/5 ( download)

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Download or read book Telomeres written by Titia De Lange and published by . This book was released on 2006 with total page 598 pages. Available in PDF, EPUB and Kindle. Book excerpt: An up-to-date survey of the current exciting state of telomere biology. Telomeres – specialized structures found at the ends of chromosomes – are essential for maintaining the integrity of chromosomes and their faithful duplication during cell division. Chapters in this volume cover telomere structure and function in a range of organisms, focusing on how they are maintained, their roles in cell division and gene expression, and how deficiencies in these structures contribute to cancers and other diseases and even aging.

Author : Pierre Capy
Publisher : Springer Science & Business Media
ISBN 13 : 9780792346906
Total Pages : 366 pages
Book Rating : 4.04/5 ( download)

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Download or read book Evolution and Impact of Transposable Elements written by Pierre Capy and published by Springer Science & Business Media. This book was released on 1998-01-31 with total page 366 pages. Available in PDF, EPUB and Kindle. Book excerpt: During the last 50 years, the perception oftransposable elements (TEs) has changed considerably from selfish DNA to sequences that may contribute significantly to genome function and evolution. The recent increased interest in TEs is based on the realization that they are a major genetic component (at least 10--20%) of all organisms and a major contributor to the mutation process. It is currently estimated that 70--80% of spontaneous mutations are the result of TE-mediated insertions, deletions, or chromosomal rearrangements. Thus, it seems at least plausible that TEs may playa significant role in the adaptation and evolution of natural populations and species. The ubiquity of TEs suggests that they are an old component of genomes which have been vertically transmitted through generations over evolutionary time. However, detailed analyses carried out over the last 20 years have revealed several unusual features of TE evolution: (i) TEs can be horizontally transferred between species; (ii) TE evolutionary rates can be dramatically increased by specific inactivation processes, such as the RIP (Repeat Induced Point mutation) mechanism in fungi; (iii) TEs can influence the regulation of other TEs by insertion or deletion; (iv) different classes of TEs in even distantly related species can be remarkably similar in both structure and function.

Author :
Publisher : Academic Press
ISBN 13 : 0123979099
Total Pages : 205 pages
Book Rating : 4.94/5 ( download)

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Download or read book Telomeres in Health and Disease written by and published by Academic Press. This book was released on 2014-06-26 with total page 205 pages. Available in PDF, EPUB and Kindle. Book excerpt: This special volume of Progress in Molecular Biology and Translational Science focuses on telomeres in health and disease. This volume covers a variety of topics with reviews written by experts in the field. Contributions from specialists in telomere diseases Informs and updates on how telomere dysfunction may cause disease in humans

Author : Keiko Hiyama
Publisher : Springer Science & Business Media
ISBN 13 : 1603278796
Total Pages : 380 pages
Book Rating : 4.99/5 ( download)

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Download or read book Telomeres and Telomerase in Cancer written by Keiko Hiyama and published by Springer Science & Business Media. This book was released on 2009-03-18 with total page 380 pages. Available in PDF, EPUB and Kindle. Book excerpt: Telomerase, an enzyme that maintains telomeres and endows eukaryotic cells with immortality, was first discovered in tetrahymena in 1985. In 1990s, it was proven that this enzyme also plays a key role in the infinite proliferation of human cancer cells. Now telomere and telomerase are widely accepted as important factors involved in cancer biology, and as promising diagnostic tools and therapeutic targets. Recently, role of telomerase in “cancer stem cells” has become another attractive story. Until now, there are several good books on telomere and telomerase focusing on biology in ciliates, yeasts, and mouse or basic sciences in human, providing basic scientists or students with updated knowledge.

Author : Nancy L. Craig
Publisher : Amer Society for Microbiology
ISBN 13 : 9781555812096
Total Pages : 1204 pages
Book Rating : 4.90/5 ( download)

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Download or read book Mobile DNA II written by Nancy L. Craig and published by Amer Society for Microbiology. This book was released on 2002 with total page 1204 pages. Available in PDF, EPUB and Kindle. Book excerpt: An extension of the original volume, reflecting the latest advances in understanding these elements. This title is published by the American Society for Microbiology Press and distributed by Taylor and Francis in rest of world territories.

Author : J. McGlade
Publisher : John Wiley & Sons
ISBN 13 : 1444311514
Total Pages : 368 pages
Book Rating : 4.18/5 ( download)

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Download or read book Advanced Ecological Theory written by J. McGlade and published by John Wiley & Sons. This book was released on 2009-04-01 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advanced Ecological Theory is intended for both postgraduate students and professional researchers in ecology. It provides an overview of current advances in the field as well as closely related areas in evolution, ecological economics, and natural-resource management, familiarizing the reader with the mathematical, computational and statistical approaches used in these different areas. The book has an exciting set of diverse contributions written by leading authorities.

Author : D. W. Deamer
Publisher : Cold Spring Harbor Perspective
ISBN 13 : 9781936113040
Total Pages : 0 pages
Book Rating : 4.4X/5 ( download)

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Download or read book The Origins of Life written by D. W. Deamer and published by Cold Spring Harbor Perspective. This book was released on 2010 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Life arose on Earth more than three billion years ago. How the first self-replicating systems emerged from prebiotic chemistry and evolved into primitive cell-like entities is an area of intense research, spanning molecular and cellular biology, organic chemistry, cosmology, geology, and atmospheric science. Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Biology provides a comprehensive account of the environment of the early Earth and the mechanisms by which the organic molecules present may have self-assembled to form replicating material such as RNA and other polymers. The contributors examine the energetic requirements for this process and focus in particular on the essential role of semi-permeable compartments in containment of primitive genetic systems. Also covered in the book are new synthetic approaches for fabricating cellular systems, the potentially extraterrestrial origin of life's building blocks, and the possibility that life once existed on Mars. Comprising five sections Setting the Stage, Components of First Life, Primitive Systems, First Polymers, and Transition to a Microbial World it is a vital reference for all scientists interested in the origin of life on Earth and the likelihood that it has arisen on other planets

Author : Marcelo Larramendy
Publisher : BoD – Books on Demand
ISBN 13 : 9535127527
Total Pages : 228 pages
Book Rating : 4.29/5 ( download)

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Download or read book Telomere written by Marcelo Larramendy and published by BoD – Books on Demand. This book was released on 2016-11-23 with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book, Telomere - A Complex End of a Chromosome, is organized into nine chapters containing the latest aspects of the current knowledge about the structure of telomeres and the crucial role that telomerase plays not only in maintaining chromosomal stability but also in relation to cell immortality, cell instability, and cancer biology. We now appreciate that these unusual complexes of DNA and proteins we all know as "telomeres" are dynamic and key structures that depend on telomerase and other cellular factors for continuance. Regulation of telomere activity is a dynamic area of current research, and new insights into telomeres and their role in aging and cancer, among other biological functions and pathologies, appear regularly in the scientific world. However, one fact is more than understandable in this difficult biological conundrum: the end of the telomere story is far from being totally unraveled.