On Tissue Engineering And Regenerative Medicine Of Skin And Its Appendages

Author : Marianna Bei
Publisher : Frontiers Media SA
ISBN 13 : 2889631079
Total Pages : 109 pages
Book Rating : 4.70/5 ( download)

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Download or read book On Tissue Engineering and Regenerative Medicine of Skin and Its Appendages written by Marianna Bei and published by Frontiers Media SA. This book was released on 2019-11-01 with total page 109 pages. Available in PDF, EPUB and Kindle. Book excerpt: Skin is the largest organ of the body and is necessary for survival, since it performs many functions such as providing a physical barrier to the external environment, sensation, retention of normal hydration and thermal regulation. Significant skin loss is associated with high mortality and morbidity in the acute phase, and with physically and cosmetically drastic scarring in the long term. Although there are a number of tissue-engineered products in the clinic that are used as skin substitutes to promote healing of traumatic burn and diabetic wounds, yet they lack several important functions including those provided by the appendages such as the hair follicles, sebaceous and sweat glands. The understanding of cellular, molecular and engineering aspects of the pathology, repair and/or regeneration of skin after wound induction is of paramount importance in order to develop the next generation of tissue engineered products with gene-enhanced capacity. In that context, we brought together scientists from basic research, translational and bioengineering fields, whose work focus on cutting-edge research associated with the acquisition of new therapeutic approaches towards skin regeneration.

Author : Mohammad Albanna
Publisher : Academic Press
ISBN 13 : 012801797X
Total Pages : 466 pages
Book Rating : 4.75/5 ( download)

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Download or read book Skin Tissue Engineering and Regenerative Medicine written by Mohammad Albanna and published by Academic Press. This book was released on 2016-01-14 with total page 466 pages. Available in PDF, EPUB and Kindle. Book excerpt: The skin is the largest human organ system. Loss of skin integrity due to injury or illness results in a substantial physiologic imbalance and ultimately in severe disability or death. From burn victims to surgical scars and plastic surgery, the therapies resulting from skin tissue engineering and regenerative medicine are important to a broad spectrum of patients. Skin Tissue Engineering and Regenerative Medicine provides a translational link for biomedical researchers across fields to understand the inter-disciplinary approaches which expanded available therapies for patients and additional research collaboration. This work expands on the primary literature on the state of the art of cell therapies and biomaterials to review the most widely used surgical therapies for the specific clinical scenarios. Explores cellular and molecular processes of wound healing, scar formation, and dermal repair Includes examples of animal models for wound healing and translation to the clinical world Presents the current state of, and clinical opportunities for, extracellular matrices, natural biomaterials, synthetic biomaterials, biologic skin substitutes, and adult and fetal stem and skin cells for skin regenerative therapies and wound management Discusses new innovative approaches for wound healing including skin bioprinting and directed cellular therapies

Author : Sophie Böttcher-Haberzeth
Publisher : Springer Nature
ISBN 13 : 1493994735
Total Pages : 260 pages
Book Rating : 4.31/5 ( download)

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Download or read book Skin Tissue Engineering written by Sophie Böttcher-Haberzeth and published by Springer Nature. This book was released on 2019-05-30 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides protocols describing the isolation and culture of diverse cell types stemming from the skin and the use of these cells and cell constructs for wound healing, bioengineering applications, and translational medicine purposes. The book is divided into three sections describing the isolation and culture of diverse skin cells, managing these cells within co-culture systems and skin models, as well as using these skin models in a test setting. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Skin Tissue Engineering: Methods and Protocols serves as a vital aid to basic and clinical researchers such as biologists, physicians, and biomedical engineers working with and being interested in basic science, and clinically and laboratory-applicable translational regenerative medicine.

Author : Julia M. Polak
Publisher : World Scientific
ISBN 13 : 1848161824
Total Pages : 947 pages
Book Rating : 4.25/5 ( download)

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Download or read book Advances in Tissue Engineering written by Julia M. Polak and published by World Scientific. This book was released on 2008 with total page 947 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Tissue Engineering is a unique volume and the first of its kind to bring together leading names in the field of tissue engineering and stem cell research. A relatively young science, tissue engineering can be seen in both scientific and sociological contexts and successes in the field are now leading to clinical reality. This book attempts to define the path from basic science to practical application. A contribution from the UK Stem Cell Bank and opinions of venture capitalists offer a variety of viewpoints, and exciting new areas of stem cell biology are highlighted. With over fifty stellar contributors, this book presents the most up-to-date information in this very topical and exciting field.

Author : Li Song
Publisher : World Scientific
ISBN 13 : 9813147768
Total Pages : 568 pages
Book Rating : 4.68/5 ( download)

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Download or read book Engineering Stem Cells For Tissue Regeneration written by Li Song and published by World Scientific. This book was released on 2017-11-24 with total page 568 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tissue engineering integrates knowledge and tools from biological sciences and engineering for tissue regeneration. A challenge for tissue engineering is to identify appropriate cell sources. The recent advancement of stem cell biology provides enormous opportunities to engineer stem cells for tissue engineering. The impact of stem cell technology on tissue engineering will be revolutionary. This book covers state-of-the-art knowledge on the potential of stem cells for the regeneration of a wide range of tissues and organs, including cardiovascular, musculoskeletal, neurological and skin tissues. The technology platforms for studying and engineering stem cells, such as hydrogel and biomaterials development, microfluidics system and microscale patterning, are also illustrated. Regulatory challenges and quality control for clinical translation are also detailed. This book provides an comprehensive update on the advancement in the field of stem cells and regenerative medicine, and serves as a valuable resource for both researchers and students. Contents: Tissue Engineering: From Basic Biology to Cell-Based Applications (R M Nerem)Recent Advances and Future Perspectives on Somatic Cell Reprogramming (K-Y Kim & I-H Park)Hematopoietic Stem Cells (J J Trowbridge)Mesenchymal Stem Cells for Tissue Regeneration (N F Huang & S Li)Delivery Vehicles for Deploying Mesenchymal Stem Cells in Tissue Repair (M S Friedman & J K Leach)Stem Cells for Cardiac Tissue Engineering (J L Young et al.)Cardiovascular System: Stem Cells in Tissue-Engineered Blood Vessels (R Sawh-Martinez et al.)Stem Cells for Vascular Regeneration: An Engineering Approach (L E Dickinson & S Gerecht)Stem Cells and Wound Repair (S H Ko et al.)Engineering Cartilage: From Materials to Small Molecules (J M Coburn & J H Elisseeff)Adult Stem Cells for Articular Cartilage Tissue Engineering (S Saha et al.)Stem Cells for Disc Repair (A A Allon et al.)Skeletal Tissue Engineering: Progress and Prospects (N J Panetta et al.)Clinical Applications of a Stem Cell Based Therapy for Oral Bone Reconstruction (B McAllister & K Haghighat)Therapeutic Strategies for Repairing the Injured Spinal Cord Using Stem Cells (M S Beattie & J C Bresnahan)Potential of Tissue Engineering and Neural Stem Cells in the Understanding and Treatment of Neurodegenerative Diseases (C Auclair-Daigle & F Berthod)High-Throughput Systems for Stem Cell Engineering (D A Brafman et al.)Microscale Technologies for Tissue Engineering and Stem Cell Differentiation (J W Nichol et al.)Quality Control of Autologous Cell- and Tissue-Based Therapies (N Dusserre et al.)Regulatory Challenges for Cell-Based Therapeutics (T McAllister et al.) Readership: Life science scientists; biomedical researchers; cell biologists; academics, postgraduate students and advanced undergraduate students in cell biology, biochemistry and genetics; surgeons; clinicians; biotechnology and pharmaceutical industry professionals. Keywords: Stem Cells;Tissue Engineering;Regenerative Medicine;Biotechnology;Cell EngineeringReview:0

Author : David L. Stocum
Publisher : Elsevier
ISBN 13 : 9780080493022
Total Pages : 464 pages
Book Rating : 4.25/5 ( download)

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Download or read book Regenerative Biology and Medicine written by David L. Stocum and published by Elsevier. This book was released on 2010-07-26 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt: The purpose of the book is to bring together in one place the different facets of regenerative biology and medicine while providing the reader with an overview of the basic and clinically-oriented research that is being done. Not only does the content cover a plethora tissues and systems, it also includes information about the developmental plasticity of adult stem cells and the regeneration of appendages. As part of its balanced presentation, Regenerative Biology and Medicine does address the biological/bioethical issues and challanges involved in the new and exciting field of regenerative biology and medicine. *Tissues covered include skin, hair, teeth, cornea, and central neural types *Systems presented are digestive, respiratory, urogenital, musculoskeletal, and cardiovascular *Includes amphibians as powerful research models *Discusses appendage regeneration in amphibians and mammals

Author : David Warburton
Publisher : World Scientific
ISBN 13 : 9814612790
Total Pages : 552 pages
Book Rating : 4.91/5 ( download)

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Download or read book Stem Cells, Tissue Engineering and Regenerative Medicine written by David Warburton and published by World Scientific. This book was released on 2014-12-15 with total page 552 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stem cells, tissue engineering and regenerative medicine are fast moving fields with vastly transformative implications for the future of health care and capital markets. This book will show the state of the art in the translational fields of stem cell biology, tissue engineering and regenerative medicine. The state of developments in specific organ systems, where novel solutions to organ failure are badly needed such as the lungs, kidney and so forth, are discussed in various chapters. These present and future advances are placed in the context of the overall field, offering a comprehensive and quick up-to-date drink from the fountain of knowledge in this rapidly emerging field. This book provides an investigator-level overview of the current field accessible to the educated scientific generalist as well as a college educated readership, undergraduates and science writers, educators and professionals of all kinds. Contents:Developmental Biology, Regenerative Medicine and Stem Cells: The Hope Machine is Justified (David Warburton)Towards Broader Approaches to Stem Cell Signaling and Therapeutics (Edwin Jesudason)Pluripotent Stem Cells from the Early Embryo (Claire E Cuddy and Martin F Pera)The First Cell Fate Decision During Mammalian Development (Melanie D White and Nicolas Plachta)Asymmetric Cell Divisions of Stem/Progenitor Cells (Ahmed HK El-Hashash)Microenvironmental Modulation of Stem Cell Differentiation with Focus on the Lung (Shimon Lecht, Collin T Stabler, Seda Karamil, Athanasios Mantalaris, Ali Samadikuchaksaraei, Julia M Polak and Peter I Lelkes)Smart Matrices for Distal Lung Tissue Engineering (Mark J Mondrinos and Peter I Lelkes)Skin Stem Cells and Their Roles in Skin Regeneration and Disorders (Chao-Kai Hsu, Chao-Chun Yang and Shyh-Jou Shieh)Stem Cell Recruitment and Impact in Skin Repair and Regeneration (Tim Hsu, Tai-Lan Tuan and Yun-Shain Lee)Epigenetic and Environmental Regulation of Skin Appendage Regeneration (Ting-Xin Jiang, Chih-Chiang Chen, Michael W Hughes, Cheng-Ming Chuong and Randall Widelitz)Cranial Neural Crest: An Extraordinarily Migratory and Multipotent Embryonic Cell Population (Samuel G Cox and J Gage Crump)Modeling Neurodegenerative Diseases and Neurodevelopmental Disorders with Reprogrammed Cells (Kate E Galloway and Justin K Ichida)Cytokine Regulation of Intestinal Stem Cells (Philip E Dubé, Unice J K Soh and D Brent Polk)The Intestinal Stem Cell Niche and Its Regulation by ErbB Growth Factor Receptors (Dana Almohazey and Mark R Frey)Tissue Engineering: Intestine (Avafia Y Dossa, Kathy A Schall, Tracy C Grikscheit and Christopher P Gayer)Liver Stem and Progenitor Cells in Development, Disease and Regenerative Medicine (Nirmala Mavila and Kasper S Wang)Lung Mesenchymal Stem Cells (Wei Shi)FGF Signaling in Lung Stem and Progenitor Cells (Soula Danopoulos and Denise Al Alam)Bioengineering Distal Airways (Christine Finck and Todd Jensen)The Isolation and Molecular Characterization of Cancer Stem Cells (Aggressive Endophenotypes) in Individual Lung Cancers (Raj K Batra, Scott Oh and Saroj Basak)Mesenchymal Stromal Cell-Based Therapies for Lung Diseases and Critical Illnesses (Fernanda Cruz, Patricia RM Rocco and Daniel J Weiss)Heart Regeneration and Repair: What We Have Learned from Model Organisms (Laurent Gamba, Michael R Harrison and Ching-Ling Lien)Leveraging Structure-Based Rational Drug Design and Nanotechnology to Destroy Leukemic Stem Cells (Fatih M Uckun, Jianjun Cheng, Cheney Mao and Sanjive Qazi)Placenta-Derived Stem Cells: Development and Preclinical Applications for Regenerative Medicine (Jennifer Izumi Divine, Hee Kyung Jung and Toshio Miki)Stem Cells in the Real World: Environmental Impacts (Theresa M Bastain, Lu Gao and Frank D Gilliland)Establishing a Research Grade Human Pluripotent Stem Cell Laboratory (Laura-Marie Nucho and Victoria Fox) Readership: Stem cell and tissue engineering scientists, patient advocates, educated laypeople, high school science students, undergraduate students, graduate students, physicians and surgeons. Key Features:This book presents up-to-date latest breakthroughs and near future applicationsBench to bedsideThis book features potential curesKeywords:Stem Cells;Tissue Engineering;Regenerative Medicine

Author : Mohammad Albanna
Publisher : Academic Press
ISBN 13 : 9780128016541
Total Pages : 352 pages
Book Rating : 4.4X/5 ( download)

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Download or read book Skin Tissue Engineering and Regenerative Medicine written by Mohammad Albanna and published by Academic Press. This book was released on 2016-02-01 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: The skin is the largest human organ system. Loss of skin integrity due to injury or illness results in a substantial physiologic imbalance and ultimately in severe disability or death. From burn victims to surgical scars and plastic surgery, the therapies resulting from skin tissue engineering and regenerative medicine are important to a broad spectrum of patients. Skin Tissue Engineering and Regenerative Medicine provides a translational link for biomedical researchers across fields to understand the inter-disciplinary approaches which expanded available therapies for patients and additional research collaboration. This work expands on the primary literature on the state of the art of cell therapies and biomaterials to review the most widely used surgical therapies for the specific clinical scenarios. . Explores cellular and molecular processes of wound healing, scar formation, and dermal repair . Includes examples of animal models for wound healing and translation to the clinical world . Presents the current state of, and clinical opportunities for, extracellular matrices, natural biomaterials, synthetic biomaterials, biologic skin substitutes, and adult and fetal stem and skin cells for skin regenerative therapies and wound management . Discusses new innovative approaches for wound healing including skin bioprinting and directed cellular therapies

Author : Ngan Huang
Publisher :
ISBN 13 : 9789813147751
Total Pages : 542 pages
Book Rating : 4.5X/5 ( download)

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Download or read book Engineering Stem Cells for Tissue Regeneration written by Ngan Huang and published by . This book was released on 2018 with total page 542 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Author : Alexandra P. Marques
Publisher : Academic Press
ISBN 13 : 9780128105450
Total Pages : 0 pages
Book Rating : 4.53/5 ( download)

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Download or read book Skin Tissue Models written by Alexandra P. Marques and published by Academic Press. This book was released on 2017-11-15 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Skin Tissue Models provides a translational link for biomedical researchers on the interdisciplinary approaches to skin regeneration. As the skin is the largest organ in the body, engineered substitutes have critical medical application to patients with disease and injury - from burn wounds and surgical scars, to vitiligo, psoriasis and even plastic surgery. This volume offers readers preliminary description of the normal structure and function of mammalian skin, exposure to clinical problems and disease, coverage of potential therapeutic molecules and testing, skin substitutes, models as study platforms of skin biology and emerging technologies. The editors have created a table of contents which frames the relevance of skin tissue models for researchers as platforms to study skin biology and therapeutic approaches for different skin diseases, for clinicians as tissue substitutes, and for cosmetic and pharmaceutical industries as alternative test substrates that can replace animal models.