Oecd Series On Testing And Assessment Guidance Document On The Reporting Of Defined Approaches To Be Used Within Integrated Approaches To Testing And Assessment

Author : OECD
Publisher : OECD Publishing
ISBN 13 : 9264274820
Total Pages : 23 pages
Book Rating : 4.22/5 ( download)

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Download or read book OECD Series on Testing and Assessment Guidance Document on the Reporting of Defined Approaches to be Used Within Integrated Approaches to Testing and Assessment written by OECD and published by OECD Publishing. This book was released on 2017-04-13 with total page 23 pages. Available in PDF, EPUB and Kindle. Book excerpt: With a view to assisting the evaluation of integrated approaches to testing and assessment (IATA) in regulatory decision-making within OECD Member Countries, this guidance document provides a set of principles for reporting defined approaches to testing and assessment that can be used as one of ...

Author : OECD
Publisher : OECD Publishing
ISBN 13 : 9264279288
Total Pages : 311 pages
Book Rating : 4.85/5 ( download)

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Download or read book OECD Series on Testing and Assessment Guidance Document on the Reporting of Defined Approaches and Individual Information Sources to be Used within Integrated Approaches to Testing and Assessment (IATA) for Skin Sensitisation written by OECD and published by OECD Publishing. This book was released on 2017-07-11 with total page 311 pages. Available in PDF, EPUB and Kindle. Book excerpt: With a view to assisting the evaluation of integrated approaches to testing and assessment (IATA) in regulatory decision-making within OECD Member Countries, this guidance document provides guidance on the reporting of defined approaches to testing and assessment in the area of skin ...

Author : OECD
Publisher : OECD Publishing
ISBN 13 : 9264891048
Total Pages : 33 pages
Book Rating : 4.43/5 ( download)

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Download or read book OECD Series on Testing and Assessment Guidance Document for the Use of Adverse Outcome Pathways in Developing Integrated Approaches to Testing and Assessment (IATA) written by OECD and published by OECD Publishing. This book was released on 2017-03-10 with total page 33 pages. Available in PDF, EPUB and Kindle. Book excerpt: The OECD has been developing guidance documents and tools for the use of alternative methods such as (Q)SAR, chemical categories and Adverse Outcome Pathways (AOPs) as a part of Integrated Approaches for Testing and Assessment (IATA). However, there is a need for a systematic framework to characterise the individual biological and toxicological relevance of alternative methods in assessing chemicals in predicting toxicological endpoints.

Author : OECD
Publisher : OECD Publishing
ISBN 13 : 9264274812
Total Pages : 29 pages
Book Rating : 4.15/5 ( download)

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Download or read book OECD Series on Testing and Assessment Report on Considerations from Case Studies on Integrated Approaches for Testing and Assessment (IATA) - First Review Cycle (2015) Case Studies on Grouping Methods as a Part of IATA written by OECD and published by OECD Publishing. This book was released on 2017-04-13 with total page 29 pages. Available in PDF, EPUB and Kindle. Book excerpt: OECD member countries have been making efforts to expand the use of alternative methods in assessing chemicals. The OECD has been developing guidance documents and tools for the use of alternative methods such as (Q)SAR, chemical categories and Adverse Outcome Pathways (AOPs) as a part of ...

Author : OECD
Publisher : OECD Publishing
ISBN 13 : 926427474X
Total Pages : 154 pages
Book Rating : 4.47/5 ( download)

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Download or read book OECD Series on Testing and Assessment Report of the Workshop on a Framework for the Development and Use Of Integrated Approaches to Testing and Assessment written by OECD and published by OECD Publishing. This book was released on 2017-04-13 with total page 154 pages. Available in PDF, EPUB and Kindle. Book excerpt: This document is a report of the Workshop on a framework for the development and use of integrated approaches to testing and assessment which was held on 17-19 November 2014 in Crystal City VA, USA. This framework should provide guiding principles, and technical guidance on how results from ...

Author : OECD
Publisher : OECD Publishing
ISBN 13 : 9264274731
Total Pages : 17 pages
Book Rating : 4.30/5 ( download)

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Download or read book OECD Series on Testing and Assessment Guidance Document for Describing Non-Guideline In Vitro Test Methods written by OECD and published by OECD Publishing. This book was released on 2017-04-13 with total page 17 pages. Available in PDF, EPUB and Kindle. Book excerpt: The purpose of this guidance is to harmonise the way non-guideline in vitro methods are described and thereby facilitate an assessment of the relevance of test methods for biological activities and responses of interest, and an assessment of the quality of data produced, irrespective of whether ...

Author : Organisation for Economic Co-operation and Development
Publisher : Organisation for Economic Co-operation and Development ; [Montréal : Renouf]
ISBN 13 : 9789264122215
Total Pages : pages
Book Rating : 4.14/5 ( download)

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Download or read book OECD Guidelines for Testing of Chemicals written by Organisation for Economic Co-operation and Development and published by Organisation for Economic Co-operation and Development ; [Montréal : Renouf]. This book was released on 1981 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Author : Gianni Dal Negro
Publisher : Academic Press
ISBN 13 : 0128212527
Total Pages : 348 pages
Book Rating : 4.23/5 ( download)

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Download or read book Practical Handbook on the 3Rs in the Context of the Directive 2010/63/EU written by Gianni Dal Negro and published by Academic Press. This book was released on 2021-11-18 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: Practical Handbook on the 3Rs in the Context of the Directive 2010/63/EU provides updated information on the EU Directive 2010/63/EU, which is the European Union legislation that protects animals being used in research. EU Directive 2010/63/EU is the European Union (EU) legislation 'on the protection of animals used for scientific purposes' and is one of the most stringent ethical and welfare standards worldwide. Closes a gap in scientific literature by addressing the need for clear guidance in walking through the multifaced universe of 3Rs Offers a useful starting point for readers and scientist who approach the 3Rs for the first-time Gives insights into the harmonization of the animal research legislation across countries

Author :
Publisher : Academic Press
ISBN 13 : 0128136987
Total Pages : 352 pages
Book Rating : 4.80/5 ( download)

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Download or read book The History of Alternative Test Methods in Toxicology written by and published by Academic Press. This book was released on 2018-10-20 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: The History of Alternative Test Methods in Toxicology uses a chronological approach to demonstrate how the use of alternative methods has evolved from their conception as adjuncts to traditional animal toxicity tests to replacements for them. This volume in the History of Toxicology and Environmental Health series explores the history of alternative test development, validation, and use, with an emphasis on humanity and good science, in line with the Three Rs (Replacement,Reduction, Refinement) concept expounded by William Russell and Rex Burch in 1959 in their now classic volume, The Principles of Humane Experimental Technique. The book describes the historical development of technologies that have influenced the application of alternatives in toxicology and safety testing. These range from single cell monocultures to sophisticated, miniaturised and microfluidic organism-on-a-chip devices, and also include molecular modelling, chemoinformatics and QSAR analysis, and the use of stem cells, tissue engineering and hollow fibre bioreactors. This has been facilitated by the wider availability of human tissues, advances in tissue culture, analytical and diagnostic methods, increases in computational processing, capabilities, and a greater understanding of cell biology and molecular mechanisms of toxicity. These technological developments have enhanced the range and information content of the toxicity endpoints detected, and therefore the relevance of test systems and data interpretation, while new techniques for non-invasive diagnostic imaging and high resolution detection methods have permitted an increased role for human studies. Several key examples of how these technologies are being harnessed to meet 21st century safety assessment challenges are provided, including their deployment in integrated testing schemes in conjunction with kinetic modelling, and in specialized areas, such as inhalation toxicity studies. The History of Alternative Test Methods in Toxicology uses a chronological approach to demonstrate how the use of alternative methods has evolved from their conception as adjuncts to traditional animal toxicity tests to replacements for them. This volume in the History of Toxicology and Environmental Health series explores the history of alternative test development, validation, and use, with an emphasis on humanity and good science, in line with the Three Rs (Replacement, Reduction, Refinement) concept expounded by William Russell and Rex Burch in 1959 in their now-classic volume, The Principles of Humane Experimental Technique. The book describes the historical development of technologies that have influenced the application of alternatives in toxicology and safety testing. These range from single cell monocultures to sophisticated miniaturised and microfluidic organism-on-a-chip devices, and also include molecular modelling, chemoinformatics and QSAR analysis, and the use of stem cells, tissue engineering and hollow fibre bioreactors. This has been facilitated by the wider availability of human tissues, advances in tissue culture, analytical and diagnostic methods, increases in computational processing capabilities, and a greater understanding of cell biology and molecular mechanisms of toxicity. These technological developments have enhanced the range and information content of the toxicity endpoints detected, and therefore the relevance of test systems and data interpretation, while new techniques for non-invasive diagnostic imaging and high resolution detection methods have permitted an increased role for human studies. Several key examples of how these technologies are being harnessed to meet 21st century safety assessment challenges are provided, including their deployment in integrated testing schemes in conjunction with kinetic modelling, and in specialised areas, such as inhalation toxicity studies.

Author : OECD
Publisher : OECD Publishing
ISBN 13 : 9264077928
Total Pages : 28 pages
Book Rating : 4.28/5 ( download)

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Download or read book OECD Guidelines for the Testing of Chemicals / OECD Series on Testing and Assessment Guidance Document for the Development of OECD Guidelines for Testing of Chemicals written by OECD and published by OECD Publishing. This book was released on 2002-05-10 with total page 28 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Monograph describes in detail the process of Test Guideline development, including the structure of the Test Guidelines Programme, the responsibilities of those involved and the procedures which should be followed.