Nuclear Pre Mrna Processing In Plants

Author : A. S. N. Reddy
Publisher : Springer Science & Business Media
ISBN 13 : 3540767762
Total Pages : 323 pages
Book Rating : 4.63/5 ( download)

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Download or read book Nuclear pre-mRNA Processing in Plants written by A. S. N. Reddy and published by Springer Science & Business Media. This book was released on 2008-04-16 with total page 323 pages. Available in PDF, EPUB and Kindle. Book excerpt: During the last few years, tremendous progress has been made in understanding various aspects of pre-mRNA processing. This book, with contributions from leading scientists in this area, summarizes recent advances in nuclear pre-mRNA processing in plants. It provides researchers in the field, as well as those in related areas, with an up-to-date and comprehensive, yet concise, overview of the current status and future potential of this research in understanding plant biology.

Author : Philippe Jeanteur
Publisher : Springer Science & Business Media
ISBN 13 : 3662097281
Total Pages : 254 pages
Book Rating : 4.81/5 ( download)

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Download or read book Regulation of Alternative Splicing written by Philippe Jeanteur and published by Springer Science & Business Media. This book was released on 2013-03-14 with total page 254 pages. Available in PDF, EPUB and Kindle. Book excerpt: The discovery in 1977 that genes are split into exons and introns has done away with the one gene - one protein dogma. Indeed, the removal of introns from the primary RNA transcript is not necessarily straightforward since there may be optional pathways leading to different messenger RNAs and consequently to different proteins. Examples of such an alternative splicing mechanism cover all fields of biology. Moreover, there are plenty of occurrences where deviant splicing can have pathological effects. Despite the high number of specific cases of alternative splicing, it was not until recently that the generality and extent of this phenomenon was fully appreciated. A superficial reading of the preliminary sequence of the human genome published in 2001 led to the surprising, and even deceiving to many scientists, low number of genes (around 32,000) which contrasted with the much higher figure around 150,000 which was previously envisioned. Attempts to make a global assessment of the use of alternative splicing are recent and rely essentially on the comparison of genomic mRNA and EST sequences as reviewed by Thanaraj and Stamm in the first chapter of this volume. Most recent estimates suggest that 40-60% of human genes might be alternatively spliced, as opposed to about 22% for C. elegans.

Author : Stefan Stamm
Publisher : John Wiley & Sons
ISBN 13 : 3527647988
Total Pages : 660 pages
Book Rating : 4.89/5 ( download)

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Download or read book Alternative pre-mRNA Splicing written by Stefan Stamm and published by John Wiley & Sons. This book was released on 2012-08-01 with total page 660 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book was written for graduate and medical students, as well as clinicians and postdoctoral researchers. It describes the theory of alternative pre-mRNA splicing in twelve introductory chapters and then introduces protocols and their theoretical background relevant for experimental research. These 43 practical chapters cover: Basic methods, Detection of splicing events, Analysis of alternative pre-mRNA splicing in vitro and in vivo, Manipulation of splicing events, and Bioinformatic analysis of alternative splicing. A theoretical introduction and practical guide for molecular biologists, geneticists,clinicians and every researcher interested in alternative splicing. Website: www.wiley-vch.de/home/splicing

Author : Adrian Krainer
Publisher : IRL Press
ISBN 13 :
Total Pages : 408 pages
Book Rating : 4.02/5 ( download)

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Download or read book Eukaryotic MRNA Processing written by Adrian Krainer and published by IRL Press. This book was released on 1997 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume focuses on the major aspects of post-transcriptional mRNA processing in the nucleus of eukaryotic cells. Each of the described mRNA reactions is required for proper gene expression and can also serve as a control point for regulating the expression of many genes, for example duringembryonic development or in different cell types. The different chapters review the assembly of newly synthesized nuclear mRNA transcripts into hnRNP particles and catalytically active spliceosomes; the structure and mechanism of action of small nuclear ribonucleoprotein particles and proteinfactors that catalyse pre-mRNA splicing in mammalian cells and in yeast; the regulation of gene expression and generation of protein isoform diversity by alternative splicing; the mechanisms of 3' end cleavage and polyadenylation; the architecture of the cell nucleus in relation to these processesand to the localization of the relevant substrates and factors; the diverse mechanisms of RNA processing by ribozymes and their potential relevance for nuclear mRNA processing; the mechanism of spliced-leader addition by trans-splicing in nematodes and trypanosomes; and the process ofinsertion/deletion mRNA editing in kinetoplasmid protozoa. In each chapter, leading researchers have provided detailed, critical reviews of the history, experimental approaches, major advances, current ideas and models, as well as future directions, for each of these active areas of research.

Author : Angus I. Lamond
Publisher : Springer Science & Business Media
ISBN 13 : 3662223252
Total Pages : 230 pages
Book Rating : 4.53/5 ( download)

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Download or read book Pre-mRNA Processing written by Angus I. Lamond and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 230 pages. Available in PDF, EPUB and Kindle. Book excerpt: he past fifteen years have seen tremendous growth in our understanding of T the many post-transcriptional processing steps involved in producing func tional eukaryotic mRNA from primary gene transcripts (pre-mRNA). New processing reactions, such as splicing and RNA editing, have been discovered and detailed biochemical and genetic studies continue to yield important new insights into the reaction mechanisms and molecular interactions involved. It is now apparent that regulation of RNA processing plays a significant role in the control of gene expression and development. An increased understanding of RNA processing mechanisms has also proved to be of considerable clinical importance in the pathology of inherited disease and viral infection. This volume seeks to review the rapid progress being made in the study of how mRNA precursors are processed into mRNA and to convey the broad scope of the RNA field and its relevance to other areas of cell biology and medicine. Since one of the major themes of RNA processing is the recognition of specific RNA sequences and structures by protein factors, we begin with reviews of RNA-protein interactions. In chapter 1 David Lilley presents an overview of RNA structure and illustrates how the structural features of RNA molecules are exploited for specific recognition by protein, while in chapter 2 Maurice Swanson discusses the structure and function of the large family of hnRNP proteins that bind to pre-mRNA. The next four chapters focus on pre-mRNA splicing.

Author : Daniel R. Schoenberg
Publisher : Springer Science & Business Media
ISBN 13 : 1592597505
Total Pages : 277 pages
Book Rating : 4.05/5 ( download)

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Download or read book mRNA Processing and Metabolism written by Daniel R. Schoenberg and published by Springer Science & Business Media. This book was released on 2008-02-05 with total page 277 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cells possess a wealth of posttranscriptional control mechanisms that impact on every conceivable aspect of the life of an mRNA. These processes are intimately intertwined in an almost baroque manner, where promoter context influences the recruitment of splicing factors, where the majority of pre-mRNAs undergo alternative splicing, and where proteins deposited during nuclear processing impact distal cytoplasmic processing, translation, and decay. If there is a unifying theme to mRNA Processing and Metabolism: Methods and Protocols, it is that mRNA processing and metabolism are integrated processes. Many of the techniques used to study mRNA have been described in a previous volume of this series (RNA–Protein Interaction Protocols, Susan Haynes, ed.) and specialized methods journals. In selecting topics for mRNA Processing and Metabolism: Methods and Protocols, I sought input on new and novel techniques and approaches that build on this foundation using technological advances in microscopy, whole genome sequencing, microarrays, mass spectrometry, fluorescent detection methodologies, and RNA interference. I have tried not to bias this book toward any single model organism, and approaches described in the various chapters use yeast, Drosophila, Xenopus, mice, plants, and cultured mammalian cells.

Author : Ezequiel Petrillo
Publisher : Frontiers Media SA
ISBN 13 : 2889639746
Total Pages : 175 pages
Book Rating : 4.48/5 ( download)

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Download or read book Alternative Splicing Regulation in Plants written by Ezequiel Petrillo and published by Frontiers Media SA. This book was released on 2020-09-02 with total page 175 pages. Available in PDF, EPUB and Kindle. Book excerpt: This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.

Author : Witold Filipowicz
Publisher : Springer Science & Business Media
ISBN 13 : 9400903537
Total Pages : 419 pages
Book Rating : 4.31/5 ( download)

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Download or read book Post-Transcriptional Control of Gene Expression in Plants written by Witold Filipowicz and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 419 pages. Available in PDF, EPUB and Kindle. Book excerpt: A recent volume of this series (Signals and Signal Transduction Pathways in Plants (K. Palme, ed.) Plant Molecular Biology 26, 1237-1679) described the relay races by which signals are transported in plants from the sites of stimuli to the gene expression machinery of the cell. Part of this machinery, the transcription apparatus, has been well studied in the last two decades, and many important mechanisms controlling gene expression at the transcriptional level have been elucidated. However, control of gene expression is by no means complete once the RNA has been produced. Important regulatory devices determine the maturation and usage of mRNA and the fate of its translation product. Post-transcriptional regulation is especially important for generating a fast response to environmental and intracellular signals. This book summarizes recent progress in the area of post-transcriptional regulation of gene expression in plants. 18 chapters of the book address problems of RNA processing and stability, regulation of translation, protein folding and degradation, as well as intracellular and cell-to-cell transport of proteins and nucleic acids. Several chapters are devoted to the processes taking place in plant organelles.

Author : Bruce Alberts
Publisher :
ISBN 13 : 9780815332183
Total Pages : 0 pages
Book Rating : 4.81/5 ( download)

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Download or read book Molecular Biology of The Cell written by Bruce Alberts and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Author : David Evans
Publisher : Taylor & Francis
ISBN 13 : 1134279833
Total Pages : 403 pages
Book Rating : 4.38/5 ( download)

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Download or read book Nuclear Envelope written by David Evans and published by Taylor & Francis. This book was released on 2004-08-02 with total page 403 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Nuclear Envelope brings together the major current topics in nuclear envelope structure, transport, transcriptional regulation and cell signaling. The volume is divided into four sections: 1. Proteins of the nuclear envelope, including nuclear envelope proteomics, structure and function. 2. Nuclear pores and transport at the nuclear envelope, including pore complex structure, assembly and function and import and export pathways. 3. Nuclear envelope dynamics, including dynamics of lamina assembly and disassembly. 4. Nuclear signaling and transcription regulation, including signaling to the nucleus and spectrin repeat proteins and their implications or communication between the nucleus and cytoplasm.