Novel Therapies For Tolerance Induction In Solid Organ And Bone Marrow Transplantation

Author : Michaela Lucas
Publisher : Frontiers Media SA
ISBN 13 : 2889743349
Total Pages : 175 pages
Book Rating : 4.46/5 ( download)

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Download or read book Novel Therapies for Tolerance Induction in Solid Organ and Bone Marrow Transplantation written by Michaela Lucas and published by Frontiers Media SA. This book was released on 2022-02-04 with total page 175 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Author : Wendy Huei-Ping SHYU
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.71/5 ( download)

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Download or read book Induction of Tolerance written by Wendy Huei-Ping SHYU and published by . This book was released on 2013 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Author : Hassan Sadozai
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.54/5 ( download)

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Download or read book Autologous Hematopoietic Stem Cell Transplantation for Tolerance Induction in a Mouse Model of Solid Organ Transplantation written by Hassan Sadozai and published by . This book was released on 2016 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The need for long term immunosuppression negatively impacts long term survival and quality of life for solid organ transplant patients. One solution for this would be establishment of immune tolerance. Autologous HSCT has been used clinically for the restoration of self-tolerance in autoimmune disease. We tested whether autologous HSCT and a short treatment with rapamycin could result in tolerance to fully MHC-mismatched allografts. Mice that received HSCT and a short course of the mTORi rapamycin demonstrated significantly prolonged allograft survival compared to untreated and rapamycin-only treated controls. Immunologic studies showed that HSCT-treated mice displayed active immune regulation as demonstrated by a primary MLR response, markedly diminished donor specific antibody levels and significantly higher frequencies of CD4+CD25+FOXP3+ Tregs. These data provide a rationale for human clinical trials to examine the ability of autologous stem cell transplantation to induce tolerance in liver transplant patients (ASCOTT) which are now ongoing.

Author : Kenneth Murphy
Publisher : Garland Science
ISBN 13 : 9780815344575
Total Pages : pages
Book Rating : 4.70/5 ( download)

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Download or read book Janeway's Immunobiology written by Kenneth Murphy and published by Garland Science. This book was released on 2010-06-22 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.

Author : Michelle Kenyon
Publisher : Springer
ISBN 13 : 3319500260
Total Pages : 311 pages
Book Rating : 4.63/5 ( download)

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Download or read book The European Blood and Marrow Transplantation Textbook for Nurses written by Michelle Kenyon and published by Springer. This book was released on 2018-03-14 with total page 311 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is open access under a CC BY 4.0 license. This textbook, endorsed by the European Society for Blood and Marrow Transplantation (EBMT), provides adult and paediatric nurses with a full and informative guide covering all aspects of transplant nursing, from basic principles to advanced concepts. It takes the reader on a journey through the history of transplant nursing, including essential and progressive elements to help nurses improve their knowledge and benefit the patient experience, as well as a comprehensive introduction to research and auditing methods. This new volume specifically intended for nurses, complements the ESH-EBMT reference title, a popular educational resource originally developed in 2003 for physicians to accompany an annual training course also serving as an educational tool in its own right. This title is designed to develop the knowledge of nurses in transplantation. It is the first book of its kind specifically targeted at nurses in this specialist field and acknowledges the valuable contribution that nursing makes in this area. This volume presents information that is essential for the education of nurses new to transplantation, while also offering a valuable resource for more experienced nurses who wish to update their knowledge.

Author : Hesham Abdeldayem
Publisher : BoD – Books on Demand
ISBN 13 : 9535125230
Total Pages : 312 pages
Book Rating : 4.35/5 ( download)

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Download or read book Frontiers in Transplantology written by Hesham Abdeldayem and published by BoD – Books on Demand. This book was released on 2016-09-07 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is addressed to researchers, practicing physicians, and surgeons in the field of organ transplantation, as well as the medical students, residents, and fellows. The topics covered include the religious concepts in organ transplantation, embryonic organ transplantation, tolerance, normothermic graft perfusion, pharmacogenetics of immunosuppressors, viral transmission in organ transplantation, pediatric and split-liver transplantation, portopulmonary hypertension, mechanical circulatory support, ex vivo lung perfusion, and ABO-incompatible kidney transplantation.

Author : Martin Erlichman
Publisher :
ISBN 13 :
Total Pages : 8 pages
Book Rating : 4.28/5 ( download)

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Download or read book Combined Liver-kidney Transplantation written by Martin Erlichman and published by . This book was released on 1995 with total page 8 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Author : Mammen Chandy
Publisher : Springer
ISBN 13 : 9783030363574
Total Pages : 0 pages
Book Rating : 4.70/5 ( download)

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Download or read book Contemporary Bone Marrow Transplantation written by Mammen Chandy and published by Springer. This book was released on 2021-03-25 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bone Marrow transplantation or Hematopoietic stem cell transplantation is a life saving procedure in a number of diseases,hematological and non hematological, which fail alternative medical management or have no other treatment options. It has transformed the lives of thousands of patients and their families around the world battling with fatal or debilitating diseases.There are many unique aspects of bone marrow transplantation which makes it very different from solid organ transplants. There is an enormous amount of research going on in this field both at clinical and basic science levels.With the rapidly changing world and field of transplantation, there is a need for an authoritative and up to date resource for transplant professionals. This book titled Contemporary Bone Marrow Transplantation aims to be a reference text comprehensively covering various facets of hematopoietic stem cell transplants with latest insights about the technique and basic science behind it . The book is the product of collective effort of transplant professionals round the world, and will reflect their experience as well as the current standard of care practices in Stem cell transplantation.The book will be divided into different sections focusing on the basic science of bone marrow transplant, the technical aspects of the procedure itself and the supportive care of transplant patients.There will also be a section each on epidemiology, upcoming trends and also case studies , which will discuss real case scenarios from the experience of the authors, to illustrate the practical challenges in managing bone marrow transplant recipients.

Author : Nicole L. Draper
Publisher : Springer
ISBN 13 : 3319898663
Total Pages : 200 pages
Book Rating : 4.67/5 ( download)

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Download or read book Chimerism written by Nicole L. Draper and published by Springer. This book was released on 2018-06-21 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text provides a comprehensive, up-to-date review of chimerism. The first part of the volume presents the causes of chimerism, specifically focusing on fertilization and early embryonic errors, pregnancy and multiple gestations, and transplantation and transfusion. The second part of the volume outlines clinical identification and consequences of chimerism. Chapters in this section focus on the effects of chimerism on testing in relationship determination and forensics, prenatal genetic testing and screening, and blood and HLA typing. This part also reviews new data concerning matching donors and recipients for transplantation, while outlining the risks of transplantation, such as graft-vs-host disease and passenger lymphocyte syndrome. Additionally, evidence on the role of chimerism in autoimmune disease and cancer is presented. Written by experts in the field, Chimerism: A Clinical Guide is a valuable resource for clinicians and researchers that will help guide patient management and stimulate investigative efforts.

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309175267
Total Pages : 134 pages
Book Rating : 4.65/5 ( download)

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Download or read book Xenotransplantation written by Institute of Medicine and published by National Academies Press. This book was released on 1996-07-12 with total page 134 pages. Available in PDF, EPUB and Kindle. Book excerpt: Xenotransplantation involves the transplantation of cells, tissues, and whole organs from one species to another. Interest in animal-to-human xenotransplants has been spurred by the continuing shortage of donated human organs and by advances in knowledge concerning the biology of organ and tissue rejection. The scientific advances and promise, however, raise complex questions that must be addressed. This book considers the scientific and medical feasibility of xenotransplantation and explores the ethical and public policy issues surrounding the possibility of renewed clinical trials. The volume focuses on the science base of xenotransplantation, public health risks of infectious disease transmission, and ethical and public policy issues, including the views of patients and their families.