Not Vital

Author : Olivier Renaud-Clément
Publisher : Hauser & Wirth
ISBN 13 : 9783906915500
Total Pages : 0 pages
Book Rating : 4.06/5 ( download)

DOWNLOAD NOW!

Download or read book Not Vital written by Olivier Renaud-Clément and published by Hauser & Wirth. This book was released on 2020 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Not Vital: SCARCH is a survey of sculptural architect Not Vital's career, published on the occasion of a January 2020 exhibition at Hauser & Wirth Somerset. Vital has created and installed responsive works that are integrated into habitats and communities around the globe: in the Engadine region of his native Switzerland and across Europe, Africa, South America, and Asia. Edited and with texts by Olivier Renaud-Clément and Giorgia von Albertini, the book features Vital's prose and poems, and additional essays by Philip Jodidio and Tilla Theus. The book brings together the far-flung locations where the artist's works are situated and envisioned, and his projects and typologies are introduced by geographic groupings. Exhibition: Hauser & Wirth Somerset, Bruton, UK (25.01.-04.05.2020).

Author : Jurgen Brockmoller
Publisher : Frontiers Media SA
ISBN 13 : 2889740293
Total Pages : 145 pages
Book Rating : 4.91/5 ( download)

DOWNLOAD NOW!

Download or read book Organic Cation Transporter 1 (OCT1): Not Vital for Life, but of Substantial Biomedical Relevance written by Jurgen Brockmoller and published by Frontiers Media SA. This book was released on 2022-01-12 with total page 145 pages. Available in PDF, EPUB and Kindle. Book excerpt: Around one third of all biologically relevant small molecules are organic cations. These include endogenous substances like catecholamines and other neurotransmitters, toxins and drugs designed to affect signaling processes. The organic cation transporter 1 (OCT1) is among the strongest expressed membrane transporters at the sinusoidal (blood-facing) side of liver cells and contributes substantially to the clearance of the blood from numerous organic cations. A most striking feature of OCT1 is its pronounced genetic diversity. Between 1 and 10% of all human populations have little to no OCT1 activity. With several of the OCT1 substrates up to 10% of Europeans are functionally OCT1 deficient. Apparently, the lack of OCT1 do not lead to apparent substantial pathological changes in these individuals. It thus appears that this transporter is not essential to human life, but does it means that OCT1 is irrelevant? In the last 25 years since the first cloning of this transporter, data on its pharmacological and physiological relevance is steadily accumulating. Numerous clinically relevant drugs (e.g. metformin, morphine, fenoterol, sumatriptan, tramadol and tropisetron) have been shown to be substrates of OCT1, and OCT1 deficiency has been shown to affect the pharmacokinetics, efficacy, or toxicity of these drugs. Also vitamin B1 has been shown to be a substrate of OCT1, and in genetically modified mice OCT1 substantially modulated hepatic lipid metabolism, total body fat and systemic glucose and lipid concentrations. Still, numerous important questions remain unsolved: For which drugs, toxins, or other endogenous or exogenous substances is OCT1 relevant? How can we predict the relevance of OCT1 from in vitro studies? What determines the substrate selectivity of OCT1 in comparison to other transporters or transport processes for organic cations? What regulates the expression of OCT1 in the liver and possibly in other tissues? What is the impact of OCT1 variation in different areas of medicine, including the therapies for cancer as well as for pulmonary, cardiovascular, or neurological diseases? How can evolutionary biology contribute to a better understanding of the roles of OCT1? And, importantly, what types of research are likely to significantly further the knowledge on OCT1 in the next decades?

Author :
Publisher :
ISBN 13 :
Total Pages : 348 pages
Book Rating : 4.14/5 ( download)

DOWNLOAD NOW!

Download or read book Advance Data from Vital & Health Statistics of the National Center for Health Statistics written by and published by . This book was released on 1976 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Author : Jordan Tannahill
Publisher : Coach House Books
ISBN 13 : 177056411X
Total Pages : 161 pages
Book Rating : 4.14/5 ( download)

DOWNLOAD NOW!

Download or read book Theatre of the Unimpressed written by Jordan Tannahill and published by Coach House Books. This book was released on 2015-05-11 with total page 161 pages. Available in PDF, EPUB and Kindle. Book excerpt: How dull plays are killing theatre and what we can do about it. Had I become disenchanted with the form I had once fallen so madly in love with as a pubescent, pimple-faced suburban homo with braces? Maybe theatre was like an all-consuming high school infatuation that now, ten years later, I saw as the closeted balding guy with a beer gut he’d become. There were of course those rare moments of transcendencethat kept me coming back. But why did they come so few and far between? A lot of plays are dull. And one dull play, it seems, can turn us off theatre for good. Playwright and theatre director Jordan Tannahill takes in the spectrum of English-language drama – from the flashiest of Broadway spectacles to productions mounted in scrappy storefront theatres – to consider where lifeless plays come from and why they persist. Having travelled the globe talking to theatre artists, critics, passionate patrons and the theatrically disillusioned, Tannahill addresses what he considers the culture of ‘risk aversion’ paralyzing the form. Theatre of the Unimpressed is Tannahill’s wry and revelatory personal reckoning with the discipline he’s dedicated his life to, and a roadmap for a vital twenty-first-century theatre – one that apprehends the value of ‘liveness’ in our mediated age and the necessity for artistic risk and its attendant failures. In considering dramaturgy, programming and alternative models for producing, Tannahill aims to turn theatre from an obligation to a destination. ‘[Tannahill is] the poster child of a new generation of (theatre? film? dance?) artists for whom "interdisciplinary" is not a buzzword, but a way of life.’ —J. Kelly Nestruck, Globe and Mail ‘Jordan is one of the most talented and exciting playwrights in the country, and he will be a force to be reckoned with for years to come.’ —Nicolas Billon, Governor General's Award–winning playwright (Fault Lines)

Author : Alma Zevi
Publisher :
ISBN 13 : 9780993084348
Total Pages : 0 pages
Book Rating : 4.46/5 ( download)

DOWNLOAD NOW!

Download or read book Muntognas written by Alma Zevi and published by . This book was released on 2016 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Muntognas, meaning 'Mountains' in the Swiss language of Romansch, the native tongue of the artist, presents eight marble, 'Dali stone' sculptures made by Vital in 2013. Mined in the Yunnan province of China, the marble has been sliced open to reveal the hidden landscapes within, inextricably linking these striking sculptures to Vital's birthplace of Sent, a tiny village in the Engadin valley of the Swiss Alps.

Author :
Publisher :
ISBN 13 :
Total Pages : 324 pages
Book Rating : 4.33/5 ( download)

DOWNLOAD NOW!

Download or read book Vital and Health Statistics written by and published by . This book was released on 1963 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Author : Cristina Bechtler
Publisher : Jrp Ringier
ISBN 13 : 9783037643501
Total Pages : 0 pages
Book Rating : 4.01/5 ( download)

DOWNLOAD NOW!

Download or read book Engadin Art Talks written by Cristina Bechtler and published by Jrp Ringier. This book was released on 2013 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume compiles ideas and projects from well-known artists, architects, designers, filmmakers and researchers on mountainous regions not only in Switzerland, but worldwide. It includes writings by Vito Acconci, Doug Aitken, Ron Arad, Nairy Baghramian and Jan von Brevern, as well as a discussion on architect Bruno Taut's "Crystal Chain Letters."

Author : Kristina M. Lyons
Publisher : Duke University Press
ISBN 13 : 1478009209
Total Pages : 147 pages
Book Rating : 4.07/5 ( download)

DOWNLOAD NOW!

Download or read book Vital Decomposition written by Kristina M. Lyons and published by Duke University Press. This book was released on 2020-04-17 with total page 147 pages. Available in PDF, EPUB and Kindle. Book excerpt: In Colombia, decades of social and armed conflict and the US-led war on drugs have created a seemingly untenable situation for scientists and rural communities as they attempt to care for forests and grow non-illicit crops. In Vital Decomposition Kristina M. Lyons presents an ethnography of human-soil relations. She follows state soil scientists and peasants across labs, greenhouses, forests, and farms and attends to the struggles and collaborations between farmers, agrarian movements, state officials, and scientists over the meanings of peace, productivity, rural development, and sustainability in Colombia. In particular, Lyons examines the practices and philosophies of rural farmers who value the decomposing layers of leaves, which make the soils that sustain life in the Amazon, and shows how the study and stewardship of the soil point to alternative frameworks for living and dying. In outlining the life-making processes that compose and decompose into soil, Lyons theorizes how life can thrive in the face of the violence, criminalization, and poisoning produced by militarized, growth-oriented development.

Author : Nick Lane
Publisher :
ISBN 13 : 9781781250372
Total Pages : 0 pages
Book Rating : 4.75/5 ( download)

DOWNLOAD NOW!

Download or read book The Vital Question written by Nick Lane and published by . This book was released on 2016 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: A game-changing book on the origins of life, called the most important scientific discovery 'since the Copernican revolution' in The Observer.

Author : Mark Rowlands
Publisher : Verso
ISBN 13 : 9781859843864
Total Pages : 244 pages
Book Rating : 4.67/5 ( download)

DOWNLOAD NOW!

Download or read book Animals Like Us written by Mark Rowlands and published by Verso. This book was released on 2002-08-17 with total page 244 pages. Available in PDF, EPUB and Kindle. Book excerpt: The US Food and Drug Administration has expressed fears that as many as 500 or 600 toxic chemicals may be present in the country's meat supply.