Neuroprogression In Psychiatric Disorders

Author : A. Halaris
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3318060518
Total Pages : 182 pages
Book Rating : 4.15/5 ( download)

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Download or read book Neuroprogression in Psychiatric Disorders written by A. Halaris and published by Karger Medical and Scientific Publishers. This book was released on 2017-07-25 with total page 182 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this volume, international experts critically review cutting-edge advances in neuroprogression research. The relevance of these findings to psychiatric and neurological disorders is clarified. Potential etiopathological mechanisms of neuroprogression are described in detail. Special emphasis is placed on the role of the immune system in stress and stress-related disorders and brain-immune interactions. The epigenetic consequences of adverse experiences in early childhood, which may prelude major psychiatric disorders, are also considered. Recent research has not only provided evidence of neuroprogression in psychiatric and neurological disorders, but has shown that pharmacologic interventions have the potential to arrest this process. Advances in testing and imaging will lead to timely diagnosis and earlier treatment. Identification of neurological mechanisms alongside (epi-)genetic vulnerability markers will create truly personalized treatment programs. This book is a valuable resource for everyone who wishes to gain insight into the essential features of the neuroprogressive course of major psychiatric and neurological disorders. In particular, psychiatrists, neuroscientists and neurologists ¬ as well as immunologists, pharmacologists and molecular biologists - will find very informative chapters of direct relevance to their field.

Author : Flávio Kapczinski
Publisher : Oxford University Press
ISBN 13 : 0191090875
Total Pages : 272 pages
Book Rating : 4.75/5 ( download)

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Download or read book Neuroprogression in Psychiatry written by Flávio Kapczinski and published by Oxford University Press. This book was released on 2019-03-06 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent studies regarding the neuropathology of specific neurological disorders suggest that both neurodevelopmental and neurodegenerative processes may play a role. However, in contrast to the neurodegeneration seen in neurological disorders such as Parkinson's and Alzheimer's disease, the term "neuroprogression" has been used to describe the neurodevelopmental aspect of pathological brain re-wiring that takes place in the context of severe psychiatric disorders, such as schizophrenia or bipolar disorder. Within psychiatry, patients with severe psychopathology, such as those depressed patients who eventually commit suicide, have been shown to present with increased inflammatory markers in the brain. A similar increase in inflammatory markers is also found in patients with bipolar disorders and schizophrenia. Thus, oxidative stress, inflammation, and changes in growth factors are thought to be the pathways of neuroprogression. Neuroprogression in Psychiatry provides a comprehensive summary of the current developments in the emerging field of neuroprogression. With contributions by leading researchers in the field, this book examines the role of neuroprogression across a wide range of specific psychiatric disorders, with chapters included on major depressive disorder, anxiety disorder, post-traumatic stress disorder, substance abuse, schizophrenia, and bipolar disorder.

Author : Flávio Kapczinski
Publisher : OUP Oxford
ISBN 13 : 0191019968
Total Pages : 368 pages
Book Rating : 4.68/5 ( download)

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Download or read book Neuroprogression and Staging in Bipolar Disorder written by Flávio Kapczinski and published by OUP Oxford. This book was released on 2015-06-11 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: After the original proposals of staging for psychotic disorders developed by McGorry and colleagues, a few systems have been put forward specifically for people with bipolar disorder. There is now consistent evidence that, at least for a significant portion of people with this disease, clinical course and outcome are not as benign as initially described. The evidence thus far points to relevant differences between early and late stages of bipolar disorders in the clinical course of illness, neurobiology and systemic pathology. These differences all suggest that staging is a viable addition to clinical care in bipolar disorder. Neuroprogression and Staging in Bipolar Disorder provides a comprehensive summary of the current state of the evidence regarding the use of staging systems in bipolar disorder. Edited by the leading researchers in the field, the book systematically covers the theoretical basis for staging, comparisons between different proposals, neurobiological underpinnings, the current evidence-base, limitations and future directions, and clinical implications and recommendations for practice. The book provides a solid and in-depth outline and thus to influence research and practice in the field of bipolar disorder.

Author : Flávio Kapczinski
Publisher :
ISBN 13 : 9780191829222
Total Pages : pages
Book Rating : 4.26/5 ( download)

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Download or read book Neuroprogression in Psychiatry written by Flávio Kapczinski and published by . This book was released on 2019 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Author : Jair Soares
Publisher : Academic Press
ISBN 13 : 9780128123478
Total Pages : 0 pages
Book Rating : 4.78/5 ( download)

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Download or read book Bipolar Disorder Vulnerability written by Jair Soares and published by Academic Press. This book was released on 2018-06-12 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bipolar Disorder Vulnerability: Perspectives from Pediatric and High-Risk Populations synthesizes our current understanding of high-risk and pediatric populations to aid readers in identifying markers of vulnerability for the development of bipolar disorder, with an ultimate goal of the development of drug targets and other therapies for early diagnosis and treatment. The book provides readers with an understanding of biological and environmental factors influencing disease manifestation that will aid them in defining discrete clinical stages and, importantly, establish an empirical basis for the application of novel therapeutics in a phase of illness during which specific treatments could more effectively alter disease course. Whereas most of the literature available on the pathophysiological mechanisms of bipolar disorder focuses on chronically ill adult individuals, this represents the only book that specifically examines pediatric and high-risk populations. An estimated 30 to 60 percent of adult bipolar disorder patients have their disease onset during childhood, with early-onset cases representing a particularly severe and genetically loaded form of the illness.

Author : Joao Quevedo
Publisher : Academic Press
ISBN 13 : 012819183X
Total Pages : 472 pages
Book Rating : 4.35/5 ( download)

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Download or read book Neurobiology of Bipolar Disorder written by Joao Quevedo and published by Academic Press. This book was released on 2020-11-25 with total page 472 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Neurobiology of Bipolar Disorder: Road to Novel Therapeutics combines the basic neurobiology of bipolar disorder with discussions of the most recent advances in research, including the interacting pathways implicated in the pathophysiology of bipolar disorder, genetic approaches and the pharmacogenomics of bipolar disorder. The basic foundational understanding of the neurobiology underlying the disorder, along with a comprehensive summary of the most recent advances in research combine to aid advanced students and researchers in their understanding of bipolar disorder management using novel and fast-acting pharmaceutical and neuromodulatory approaches. Aids readers in understanding bipolar disorder in the context of NIMH Research Domain Criteria (RDoC) recommendations Covers a range of existing and potential pharmacologic and non-pharmacologic treatment options, from lifestyle adjustments to novel therapeutics Synthesizes a discussion of the cellular and molecular mechanisms underlying symptoms with clinical aspects of bipolar disorder

Author : Allan H. Young
Publisher : Springer Nature
ISBN 13 : 3030721434
Total Pages : 325 pages
Book Rating : 4.35/5 ( download)

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Download or read book Bipolar Disorder: From Neuroscience to Treatment written by Allan H. Young and published by Springer Nature. This book was released on 2021-03-29 with total page 325 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bipolar disorder is a common, complex and costly mental health disorder, which sits at the heart of the practice of clinical psychiatry. Effective treatments (pharmacological, psychological and brain stimulation based) have all been discovered serendipitously. With the huge advances in basic neuroscience the way is now clear for novel treatments to be developed based on brain science. This book reviews these possibilities.

Author : Johannes Hebebrand
Publisher : Elsevier Health Sciences
ISBN 13 : 0323548539
Total Pages : 400 pages
Book Rating : 4.33/5 ( download)

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Download or read book Eating Disorders and Obesity in Children and Adolescents written by Johannes Hebebrand and published by Elsevier Health Sciences. This book was released on 2018-12-07 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: Get a quick, expert overview of best practices for diagnosis and treatment of eating disorders in children and adolescents. This concise resource by Drs. Johannes Hebebrand and Beate Herpertz-Dahlmann provides psychiatrists and pediatricians with current information in this increasingly important field, including practical sections on developmental aspects of eating disorders, symptomology, epidemiology, etiology and pathyphysiology, treatment and outcomes, and prevention. Discusses general concepts for feeding, eating, and weight disorders; body weight and composition, appetite regulation, and the emergence of body perception and image. Covers genetics of eating and weight disorders, influence of hormones, intergenerational effects, and food addiction. Includes information on cognitive behavioral therapy, family-based therapies, early intervention, pharmacotherapy, bariatric surgery, and other treatments. Consolidates today’s available information on this timely topic into a single convenient resource.

Author : Ather Muneer
Publisher : Routledge
ISBN 13 : 1351370774
Total Pages : 212 pages
Book Rating : 4.76/5 ( download)

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Download or read book Mood Disorders written by Ather Muneer and published by Routledge. This book was released on 2018-02-01 with total page 212 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mood Disorders: Practical Issues in Diagnosis and Management provides cutting edge knowledge about the diagnosis and treatment of principal mood disorders, namely major depressive disorder and bipolar disorder. Covering diagnosis, differentiating features, and illness course and trajectories of principal mood disorders, Dr. Ather Muneer provides essential information in a succinct and practical manner, while highlighting significant new findings in the area. This book will help a broad range of mental health professionals better treat the millions of people with mood disorders across the globe.

Author : Bernhard Baune
Publisher : Academic Press
ISBN 13 : 0128110740
Total Pages : 636 pages
Book Rating : 4.44/5 ( download)

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Download or read book Inflammation and Immunity in Depression written by Bernhard Baune and published by Academic Press. This book was released on 2018-05-23 with total page 636 pages. Available in PDF, EPUB and Kindle. Book excerpt: Inflammation and Immunity in Depression: Basic Science and Clinical Applications is the first book to move beyond the established theory of cytokine-induced depression and explore the broader role the immune system plays in this devastating mood disorder. The book fully explores the most recent lines of research into this rapidly advancing field, including alterations of T-cells, the neurobiological implications of neuroinflammation and immune alterations for brain development and function, and the genetic components of neuroinflammation in depression, including the relationships between stress and inflammation that are revealing gene-environment interactions in the disorder. Combining contributions from researchers worldwide, this book provides the most comprehensive discussion available today on the involvement of the innate immune and adaptive immune systems in depressive disorder. Chapters span neuroscience, psychology, clinical applications and future directions, making this book an invaluable resource for advanced students, researchers and practitioners who need to understand the complex and varied role of inflammation and immune responses in depression. Synthesizes current knowledge of inflammation and immunity in depression, ranging from basic neuroscience research, to clinical applications in psychiatry Expands on the long-established theory of cytokine-induced depression to discuss broader involvement of the immune system Explores translational potential of targeting immune dysfunction for clinical interventions