Multifunctional Hydrogels For Biomedical Applications

Author : Ricardo A. Pires
Publisher : John Wiley & Sons
ISBN 13 : 352734716X
Total Pages : 388 pages
Book Rating : 4.62/5 ( download)

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Download or read book Multifunctional Hydrogels for Biomedical Applications written by Ricardo A. Pires and published by John Wiley & Sons. This book was released on 2022-05-31 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: Multifunctional Hydrogels for Biomedical Applications Comprehensive resource presenting a thorough overview of the biomedical applications of hydrogels This book provides an overview of the development and applications of the clinically relevant hydrogels that are used particularly in tissue engineering, regenerative medicine, and drug delivery. Taking a multidisciplinary approach, it goes through the material from chemistry, materials science, biology, medicine, nanotechnology, and bioengineering points of view. Sample topics covered by the three well-qualified editors include: The design, functions, and developments of hydrogels Proteins and polysaccharides that mimic extracellular matrix Generation and applications of supramolecular hydrogels Design and functions of cell encapsulation systems Multifunctional Hydrogels for Biomedical Applications is a useful all-in-one reference work for materials scientists, polymer chemists, and bioengineers which provides a comprehensive, contemporary understanding of hydrogels and their applications targeting a wide variety of pathologies.

Author : José García-Torres
Publisher : CRC Press
ISBN 13 : 1040009999
Total Pages : 413 pages
Book Rating : 4.94/5 ( download)

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Download or read book Multifunctional Hydrogels written by José García-Torres and published by CRC Press. This book was released on 2024-04-19 with total page 413 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hydrogels are important polymer-based materials with innate fascinating properties and applications: they are three-dimensional, hydrophilic, polymeric networks that can absorb large amounts of water or aqueous fluids and are biocompatible, mechanically flexible, and soft. The incorporation of functionalities to develop smart and bioactive platforms has led to a myriad of applications. This book offers a comprehensive overview of multifunctional hydrogels, covering fundamentals, properties, and advanced applications in a progressive way. While each chapter can be read stand-alone, together they clearly describe the fundamental concepts of design, synthesis, and fabrication, as well as properties and performances of smart multifunctional hydrogels and their advanced applications in the biomedical, environmental, and robotics fields. This book: • Introduces readers to different hydrogel materials and the polymer types used to fabricate them. • Discusses conducting polymer hydrogels, nanocomposite hydrogels, and self-healing hydrogels. • Covers synthesis methodologies and fabrication techniques commonly used to confer certain structures and/or architectures. • Shows how hydrogels can be modified to incorporate new functionalities able to respond to physical and/or chemical changes. • Examines applications including bioelectronics, sensors and biosensors, tissue engineering, drug delivery, antipathogen applications, cancer theranostics, environmental applications, and soft robotics, with chapters showcasing the main advances achieved up to date in every field. Multifunctional Hydrogels: From Basic Concepts to Advanced Applications serves as a valuable resource for academic and industry researchers from interdisciplinary fields including materials science, chemistry, chemical engineering, bioengineering, physics, and pharmaceutical engineering.

Author : Sharon Bolanta
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.22/5 ( download)

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Download or read book Synthesis and Characterisation of Multifunctional Hydrogels for Biomedical Applications written by Sharon Bolanta and published by . This book was released on 2021 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Author : Ricardo A. Pires
Publisher : John Wiley & Sons
ISBN 13 : 3527825835
Total Pages : 388 pages
Book Rating : 4.37/5 ( download)

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Download or read book Multifunctional Hydrogels for Biomedical Applications written by Ricardo A. Pires and published by John Wiley & Sons. This book was released on 2022-05-12 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: Multifunctional Hydrogels for Biomedical Applications Comprehensive resource presenting a thorough overview of the biomedical applications of hydrogels This book provides an overview of the development and applications of the clinically relevant hydrogels that are used particularly in tissue engineering, regenerative medicine, and drug delivery. Taking a multidisciplinary approach, it goes through the material from chemistry, materials science, biology, medicine, nanotechnology, and bioengineering points of view. Sample topics covered by the three well-qualified editors include: The design, functions, and developments of hydrogels Proteins and polysaccharides that mimic extracellular matrix Generation and applications of supramolecular hydrogels Design and functions of cell encapsulation systems Multifunctional Hydrogels for Biomedical Applications is a useful all-in-one reference work for materials scientists, polymer chemists, and bioengineers which provides a comprehensive, contemporary understanding of hydrogels and their applications targeting a wide variety of pathologies.

Author : Anujit Ghosal
Publisher : CRC Press
ISBN 13 : 1000056147
Total Pages : 164 pages
Book Rating : 4.43/5 ( download)

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Download or read book Intelligent Hydrogels in Diagnostics and Therapeutics written by Anujit Ghosal and published by CRC Press. This book was released on 2020-05-27 with total page 164 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explores the potential of hydrogels as a multiutility system and their benefits (biocompatibility, degradability, and supporting scaffolds) for a wide range of applications in diagnostics and therapeutics. It also discusses the future prospects and challenges facing hydrogels. A wide variety of smart hydrogels (conducting, stimuli responsive, and others) with possible biomedical applications are elaborated. The book demonstrates the effectiveness of hydrogels in diagnostics of diseases in various in vivo and in vitro environments and highlights the engineering/functionalization of hydrogels for everyday drug dosage as an efficient drug carrier, scaffold, and sensing application. Explores the potential of hydrogels as a multifunctional system and their benefits, particularly for biomedical applications in diagnostics as well as therapeutics. Highlights the designing and engineering of hydrogels for everyday drug dosage and possible functionalization to fabricate an efficient drug carrier. Examines the significance of biopolymer-based hydrogels and their responsiveness in different physiological fluids. Demonstrates the effectiveness of hydrogels in diagnostics of diseases in various in,vivo and in,vitro environments. Presents challenges associated with the hydrogels and discusses possible in-hand modifications at length. Dr. Anujit Ghosal worked in the School of Biotechnology, Jawaharlal Nehru University, India. Currently, he is affiliated with the School of Life Sciences, Beijing Institute of Technology, Beijing, PRC. Dr. Ghosal researches in biochemistry, polymer chemistry, and nanotechnology. He has been the recipient of prestigious fellowships throughout his research career. His research ability is proven by his published peer-reviewed research and review articles and contributed book chapters. Dr. Ajeet Kaushik works as an assistant professor of chemistry and is exploring advanced electrochemical sensing systems and nanomedicine for personalized health wellness at the Department of Natural Sciences of the Division of Science, Arts, and Mathematics at Florida Polytechnic University, Lakeland, US. He is the recipient of various reputed awards for his service in the area of nanobiotechnology for health care. His excellent research credentials are reflected by his four edited books, 100 international research peer-reviewed publications, and three patents in the area of nanomedicine and smart biosensors for personalized health care.

Author : Vijay Kumar Thakur
Publisher : Springer
ISBN 13 : 9811060770
Total Pages : 470 pages
Book Rating : 4.79/5 ( download)

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Download or read book Hydrogels written by Vijay Kumar Thakur and published by Springer. This book was released on 2018-08-28 with total page 470 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses recent advances in hydrogels, including their generation and applications and presents a compendium of fundamental concepts. It highlights the most important hydrogel materials, including physical hydrogels, chemical hydrogels, and nanohydrogels and explores the development of hydrogel-based novel materials that respond to external stimuli, such as temperature, pressure, pH, light, biochemicals or magnetism, which represent a new class of intelligent materials. With their multiple cooperative functions, hydrogel-based materials exhibit different potential applications ranging from biomedical engineering to water purification systems. This book covers key topics including superabsorbent polymer hydrogel; intelligent hydrogels for drug delivery; hydrogels from catechol-conjugated materials; nanomaterials loaded hydrogel; electrospinning of hydrogels; biopolymers-based hydrogels; injectable hydrogels; interpenetrating-polymer-network hydrogels: radiation- and sonochemical synthesis of micro/nano/macroscopic hydrogels; DNA-based hydrogels; and multifunctional applications of hydrogels. It will prove a valuable resource for researchers working in industry and academia alike.

Author : Kangde Yao
Publisher : CRC Press
ISBN 13 : 1439821151
Total Pages : 492 pages
Book Rating : 4.52/5 ( download)

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Download or read book Chitosan-Based Hydrogels written by Kangde Yao and published by CRC Press. This book was released on 2016-04-19 with total page 492 pages. Available in PDF, EPUB and Kindle. Book excerpt: Due to their unique properties, chitosan-based materials have emerged as useful resources in a variety of medicines, drug controlled-release carriers, tissue engineering scaffolds, and immobilized enzymes. But many of these materials have yet to reach the commercial market. Therefore, more work must be completed to fill the gap between research and

Author : Qinghua Wu
Publisher :
ISBN 13 :
Total Pages : 134 pages
Book Rating : 4.28/5 ( download)

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Download or read book 3D Printing of Multifunctional Chitosan-based Hydrogels and Nanocomposites written by Qinghua Wu and published by . This book was released on 2018 with total page 134 pages. Available in PDF, EPUB and Kindle. Book excerpt: The ability to produce complex micro- or nano-structures in soft materials is significant for various applications such as tissue engineering, sensors, drug delivery and medical devices. In tissues or organs, surrounding micro-environments can affect cell alignment and organization that lead to the biological and functional complexity of native tissues. Naturally derived hydrogels are an important class of soft materials, which are exceptionally attractive for biomedical applications since they simulate the aqueous environment of extracellular matrices. However, precisely controlled architectures of naturally derived hydrogels are difficult to obtain through most conventional fabrication methods, and even with three-dimensional (3D) printing. Despite recent progress in the field of additive manufacturing, significant challenges persist to fabricate hydrogels with ordered structures and adequate mechanical and biological properties for mimicking native tissues. Besides, electronic waste and environmental pollution is a serious issue due to constant demand for newer and more powerful electronics. Many non-biodegradable polymers and toxic components are found in traditional electronics (such as capacitors and integrated circuits), and toxic solvents (such as isopropanol, acetone and trichloroethylene) are on occasion used in their fabrication. With the growing importance of sustainable development, it is of the upmost priority for companies in the electronic industry to develop and fabricate eco-friendly electronics. Natural polymer-based nanocomposites are excellent candidates for developing the next-generation of bio-sustainable electronics due to their lightweight, low-cost, and sustainable properties. Thus, in this work, we develop a 3D printing process to fabricate 3D microstructures of a natural polymer - namely chitosan (CS) - and its nanocomposites. This work proposes CS-based inks that can be fabricated by 3D printing at room temperature. The setup of 3D printing is composed of a computer-controlled translation stage and a three-axis positioning platform. The ink is loaded into a syringe, which can be extruded through a micronozzle. The ink filaments are deposited on the plate to form a structure in a layer-by-layer manner, where it undergoes filament solidification through solvent evaporation. We demonstrate a comprehensive characterization of the properties of CS inks for 3D printing at room temperature. The rheological properties of CS inks are analyzed by rotational rheometry at low to moderate shear rate and the process-related viscosity and flow behavior are characterized by capillary flow analysis, in order to formulate inks with shear thinning behavior for successful 3D printing. Solvent evaporation tests of different ink compositions are investigated by observing the weight reduction of extruded CS filaments with time. Since different structures fabricated by 3D printing require different processing parameters, a processing map is generated by considering parameters such as micronozzle diameter and ink concentration for the successful fabrication of one-dimensional (1D), two-dimensional (2D) and 3D CS structures. The results of X-ray diffraction (XRD) and tensile properties of CS filaments are also investigated, showing different material properties obtained after different processing steps. The 3D-printed scaffolds show controllable pore shapes (such as gradient, square- and diamond-shaped pores) and a high resolution of 30 μm. Microstructured hydrogel scaffolds with wrinkled surface are obtained through a gelation step of neutralization in sodium hydroxide. The as-printed and neutralized scaffolds show highly flexible and stretchable behaviors. The strain at break of CS hydrogel filaments reaches up to ~ 400% and maximum strength is ~ 7.5 MPa. The microstructured hydrogels can guide fibroblast cell growth and induce cell alignment. Further, CS-based nanocomposites made of CS as a polymer matrix, multi-walled carbon nanotube (CNT) as a nanofiller and a solvent mixture are prepared using a ball mill mixing method. The CS/CNT nanocomposite inks are developed to exhibit self-healing at room temperature. The healing properties can be processed via exposure to water vapor and the nanocomposite can restore electrical conductivity and mechanical properties. The self-healing is rapid, occurring within seconds after the damage of the nanocomposite. 3D printing enables us to fabricate highly conductive (~ 1450 S/m) CS/CNT nanocomposites. Instability-assisted 3D printing is developed to fabricate high tunable microstructured CS/CNT fibers, due to the liquid rope coiling instability. Microstructured CS/CNT fibers featuring sacrificial bonds and hidden length allow the nanocomposites with high stretchability (strain at break of ~ 180%). The high stretchability and conductivity of CS/CNT fibers enable the nanocomposite to be designed as wearable sensors. The customized strain sensors are fabricated by instability-assisted 3D printing and demonstrate their ability to detect human elbow motions. The CS/CNT nanocomposite can be also used to sense the humidity owing to polymer swelling under different environment humidity. The novel 3D printing method of tailoring CS hydrogels and CS/CNT nanocomposites demonstrated here opens new doors to design and produce 3D tissue constructs with topographical, biological, and mechanical compatibility as well as wearable sensor exhibiting strain and humidity sensing ability.

Author : Steve Rimmer
Publisher : Elsevier
ISBN 13 : 0857091387
Total Pages : 280 pages
Book Rating : 4.83/5 ( download)

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Download or read book Biomedical Hydrogels written by Steve Rimmer and published by Elsevier. This book was released on 2011-02-26 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hydrogels are very important for biomedical applications because they can be chemically manipulated to alter and control the hydrogel’s interaction with cells and tissues. Their flexibility and high water content is similar to that of natural tissue, making them extremely suitable for biomaterials applications. Biomedical hydrogels explores the diverse range and use of hydrogels, focusing on processing methods and novel applications in the field of implants and prostheses. Part one of this book concentrates on the processing of hydrogels, covering hydrogel swelling behaviour, superabsorbent cellulose-based hydrogels and regulation of novel hydrogel products, as well as chapters focusing on the structure and properties of hydrogels and different fabrication technologies. Part two covers existing and novel applications of hydrogels, including chapters on spinal disc and cartilage replacement implants, hydrogels for ophthalmic prostheses and hydrogels for wound healing applications. The role of hydrogels in imaging implants in situ is also discussed. With its distinguished editor and international team of contributors, Biomedical hydrogels is an excellent reference for biomedical research scientists and engineers in industry and academia, as well as others involved in research in this area, such as research clinicians. Examines the diverse range and use of hydrogels, focusing on processing methods and novel applications Comprehensive book explores the structure and properties of hydrogels and different fabrication technologies Covers important areas such as processing of hydrogels, covering hydrogel swelling behaviour, superabsorbent cellulose-based hydrogels and regulation of novel hydrogel products

Author : Lacramioara Popa
Publisher : BoD – Books on Demand
ISBN 13 : 1789858755
Total Pages : 133 pages
Book Rating : 4.54/5 ( download)

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Download or read book Hydrogels written by Lacramioara Popa and published by BoD – Books on Demand. This book was released on 2019-04-10 with total page 133 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hydrogels, as three-dimensional polymer networks, are able to retain a large amount of water in their swollen state. The biomedical application of hydrogels was initially hampered by the toxicity of cross-linking agents and the limitations of hydrogel formation under physiological conditions. However, emerging knowledge in polymer chemistry and an increased understanding of biological processes have resulted in the design of versatile materials and minimally invasive therapies.The novel but challenging properties of hydrogels are attracting the attention of researchers in the biological, medical, and pharmaceutical fields. In the last few years, new methods have been developed for the preparation of hydrophilic polymers and hydrogels, which may be used in future biomedical and drug delivery applications. Such efforts include the synthesis of self-organized nanostructures based on triblock copolymers with applications in controlled drug delivery. These hydrogels could be used as carriers for drug delivery when combined with the techniques of drug imprinting and subsequent release. Engineered protein hydrogels have many potential advantages. They are excellent biomaterials and biodegradables. Furthermore, they could encapsulate drugs and be used in injectable forms to replace surgery, to repair damaged cartilage, in regenerative medicine, or in tissue engineering. Also, they have potential applications in gene therapy, although this field is relatively new.