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Author : Indra Mani
Publisher : Springer Nature
ISBN 13 : 9819718449
Total Pages : 357 pages
Book Rating : 4.43/5 ( download)
Download or read book Multi-Omics Analysis of the Human Microbiome written by Indra Mani and published by Springer Nature. This book was released on with total page 357 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Indra Mani
Publisher : Springer
ISBN 13 : 9789819718436
Total Pages : 0 pages
Book Rating : 4.30/5 ( download)
Download or read book Multi-Omics Analysis of the Human Microbiome written by Indra Mani and published by Springer. This book was released on 2024-06-10 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book introduces the rapidly evolving field of multi-omics in understanding the human microbiome. The book focuses on the technology used to generate multi-omics data, including advances in next-generation sequencing and other high-throughput methods. It also covers the application of artificial intelligence and machine learning algorithms to the analysis of multi-omics data, providing readers with an overview of the powerful computational tools that are driving innovation in this field. The chapter also explores the various bioinformatics databases and tools available for the analysis of multi-omics data. The book also delves into the application of multi-omics technology to the study of microbial diversity, including metagenomics, metatranscriptomics, and metaproteomics. The book also explores the use of these techniques to identify and characterize microbial communities in different environments, from the gut and oral microbiome to the skin microbiome and beyond. Towards theend, it focuses on the use of multi-omics in the study of microbial consortia, including mycology and the viral microbiome. The book also explores the potential of multi-omics to identify genes of biotechnological importance, providing readers with an understanding of the role that this technology could play in advancing biotech research. Finally, the book concludes with a discussion of the clinical applications of multi-omics technology, including its potential to identify disease biomarkers and develop personalized medicine approaches. Overall, this book provides readers with a comprehensive overview of this exciting field, highlighting the potential for multi-omics to transform our understanding of the microbial world.
Author : Himel Mallick
Publisher : Frontiers Media SA
ISBN 13 : 2889660915
Total Pages : 170 pages
Book Rating : 4.19/5 ( download)
Download or read book Statistical and Computational Methods for Microbiome Multi-Omics Data written by Himel Mallick and published by Frontiers Media SA. This book was released on 2020-11-19 with total page 170 pages. Available in PDF, EPUB and Kindle. Book excerpt: This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
Author : Food Forum
Publisher : National Academies Press
ISBN 13 : 030926586X
Total Pages : 197 pages
Book Rating : 4.67/5 ( download)
Download or read book The Human Microbiome, Diet, and Health written by Food Forum and published by National Academies Press. This book was released on 2013-02-27 with total page 197 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Food Forum convened a public workshop on February 22-23, 2012, to explore current and emerging knowledge of the human microbiome, its role in human health, its interaction with the diet, and the translation of new research findings into tools and products that improve the nutritional quality of the food supply. The Human Microbiome, Diet, and Health: Workshop Summary summarizes the presentations and discussions that took place during the workshop. Over the two day workshop, several themes covered included: The microbiome is integral to human physiology, health, and disease. The microbiome is arguably the most intimate connection that humans have with their external environment, mostly through diet. Given the emerging nature of research on the microbiome, some important methodology issues might still have to be resolved with respect to undersampling and a lack of causal and mechanistic studies. Dietary interventions intended to have an impact on host biology via their impact on the microbiome are being developed, and the market for these products is seeing tremendous success. However, the current regulatory framework poses challenges to industry interest and investment.
Author : Angela Zhang
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.47/5 ( download)
Download or read book Statistical Tools for the Multi-omics Analysis of Microbiome Data written by Angela Zhang and published by . This book was released on 2022 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The human microbiome consists of trillions of bacteria, archaea, and viruses that exist on virtually every organ in the body. The microbiome plays a fundamental role in human health and has been implicated in several different diseases and conditions such as cardiovascular disease and certain cancers. Understanding the functional role of the microbiome can lead to increased understanding of these complex diseases and result in the development of more effective treatments. Although advances in technology have allowed for the inexpensive processing and analysis of high-throughput data, several statistical challenges exist in the analysis of microbiome data. In my dissertation, I will present three projects that address the statistical challenges of high-dimensionality, multi-omics data integration, batch effects/other covariate adjustment, and the visualization of microbiome data. In Project 1, We address the issues of high-dimensionality and data integration by proposing a new procedure for testing the cumulative metabolic effect of the microbiome using a weighted variance component test framework. In this setup, we focus on metabolic pathways and recognize that metabolism can be represented by metagenomics (metabolic potential) and metabolomics (metabolic output). In Project 2, we address the issue of batch effects and high-dimensionality by outlining a two-step adjustment of the principal coordinates (PCs) of the microbial taxa data. In the first step, we project the mean effect of the unwanted covariates out of the PCs. In the second step, we adjust out the second moment of the same covariates from the PCs by assuming a linear relationship between the covariates and the variance of the PCs. Finally, in Project 3, we propose an effect modification testing procedure for evaluating interactions between microbial taxa and environmental factors on an outcome of interest. We address concerns of data integration and high-dimensionality by using a variance component test framework with LASSO-selected variables to assess the effect modification of the microbiome on environmental variables.
Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 030910159X
Total Pages : 791 pages
Book Rating : 4.92/5 ( download)
Download or read book Preterm Birth written by Institute of Medicine and published by National Academies Press. This book was released on 2007-05-23 with total page 791 pages. Available in PDF, EPUB and Kindle. Book excerpt: The increasing prevalence of preterm birth in the United States is a complex public health problem that requires multifaceted solutions. Preterm birth is a cluster of problems with a set of overlapping factors of influence. Its causes may include individual-level behavioral and psychosocial factors, sociodemographic and neighborhood characteristics, environmental exposure, medical conditions, infertility treatments, and biological factors. Many of these factors co-occur, particularly in those who are socioeconomically disadvantaged or who are members of racial and ethnic minority groups. While advances in perinatal and neonatal care have improved survival for preterm infants, those infants who do survive have a greater risk than infants born at term for developmental disabilities, health problems, and poor growth. The birth of a preterm infant can also bring considerable emotional and economic costs to families and have implications for public-sector services, such as health insurance, educational, and other social support systems. Preterm Birth assesses the problem with respect to both its causes and outcomes. This book addresses the need for research involving clinical, basic, behavioral, and social science disciplines. By defining and addressing the health and economic consequences of premature birth, this book will be of particular interest to health care professionals, public health officials, policy makers, professional associations and clinical, basic, behavioral, and social science researchers.
Author : National Academies of Sciences, Engineering, and Medicine
Publisher : National Academies Press
ISBN 13 : 0309458390
Total Pages : 133 pages
Book Rating : 4.99/5 ( download)
Download or read book The Chemistry of Microbiomes written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2017-07-19 with total page 133 pages. Available in PDF, EPUB and Kindle. Book excerpt: The 21st century has witnessed a complete revolution in the understanding and description of bacteria in eco- systems and microbial assemblages, and how they are regulated by complex interactions among microbes, hosts, and environments. The human organism is no longer considered a monolithic assembly of tissues, but is instead a true ecosystem composed of human cells, bacteria, fungi, algae, and viruses. As such, humans are not unlike other complex ecosystems containing microbial assemblages observed in the marine and earth environments. They all share a basic functional principle: Chemical communication is the universal language that allows such groups to properly function together. These chemical networks regulate interactions like metabolic exchange, antibiosis and symbiosis, and communication. The National Academies of Sciences, Engineering, and Medicine's Chemical Sciences Roundtable organized a series of four seminars in the autumn of 2016 to explore the current advances, opportunities, and challenges toward unveiling this "chemical dark matter" and its role in the regulation and function of different ecosystems. The first three focused on specific ecosystemsâ€"earth, marine, and humanâ€"and the last on all microbiome systems. This publication summarizes the presentations and discussions from the seminars.
Author : Roshan Kumar
Publisher : Frontiers Media SA
ISBN 13 : 2832501206
Total Pages : 179 pages
Book Rating : 4.07/5 ( download)
Download or read book Multi-omics Profiling of Unique Niches to Reveal the Microbial and Metabolite Composition written by Roshan Kumar and published by Frontiers Media SA. This book was released on 2022-09-29 with total page 179 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Kang Ning
Publisher : Springer Nature
ISBN 13 : 9811982104
Total Pages : 173 pages
Book Rating : 4.01/5 ( download)
Download or read book Methodologies of Multi-Omics Data Integration and Data Mining written by Kang Ning and published by Springer Nature. This book was released on 2023-01-15 with total page 173 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book features multi-omics big-data integration and data-mining techniques. In the omics age, paramount of multi-omics data from various sources is the new challenge we are facing, but it also provides clues for several biomedical or clinical applications. This book focuses on data integration and data mining methods for multi-omics research, which explains in detail and with supportive examples the “What”, “Why” and “How” of the topic. The contents are organized into eight chapters, out of which one is for the introduction, followed by four chapters dedicated for omics integration techniques focusing on several omics data resources and data-mining methods, and three chapters dedicated for applications of multi-omics analyses with application being demonstrated by several data mining methods. This book is an attempt to bridge the gap between the biomedical multi-omics big data and the data-mining techniques for the best practice of contemporary bioinformatics and the in-depth insights for the biomedical questions. It would be of interests for the researchers and practitioners who want to conduct the multi-omics studies in cancer, inflammation disease, and microbiome researches.
Author : Zhangran Chen
Publisher : Frontiers Media SA
ISBN 13 : 2889765806
Total Pages : 131 pages
Book Rating : 4.05/5 ( download)
Download or read book Multi-omics Study on Gut Microbiota Related to Faecal Microbiota Transplantation written by Zhangran Chen and published by Frontiers Media SA. This book was released on 2022-07-18 with total page 131 pages. Available in PDF, EPUB and Kindle. Book excerpt:
