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Author : Wolfgang Holnthoner
Publisher : Frontiers Media SA
ISBN 13 : 2889663205
Total Pages : 199 pages
Book Rating : 4.00/5 ( download)
Download or read book MSC Signaling in Regenerative Medicine written by Wolfgang Holnthoner and published by Frontiers Media SA. This book was released on 2021-01-04 with total page 199 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Nikolai V. Gorbunov
Publisher : Elsevier
ISBN 13 : 0128227567
Total Pages : 208 pages
Book Rating : 4.65/5 ( download)
Download or read book Tissue Barriers in Disease, Injury and Regeneration written by Nikolai V. Gorbunov and published by Elsevier. This book was released on 2021-06-19 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tissue Barriers in Disease, Injury and Regeneration focuses on the molecular and cellular fundamentals of homeostatic and defense responses of tissue barriers, covering the damaging impacts and exposure to pathogens and engineered nanomaterials. Sections emphasize the role of mesenchymal stoma, vascular, epithelial, telocyte, myofibroblast, lymphoid and reticuloendothelial cells, along with reactions that bridge the effects of ambient factors, medical treatments, drag delivery systems with alterations in barrier integrity, tissue/organ functions, and metabolic status. Other sections cover the role of progenitor cells of different origins in the remodeling and regeneration of tissue stroma, vasculature of blood-tissue barriers, and more. Includes special emphasis on the role of mesenchymal stoma, vascular, epithelial, telocyte, myofibroblast, lymphoid and reticuloendothelial cells in the development of reactions that bridge the effects of ambient factors, medical treatments, drag delivery systems with alterations in barrier integrity, tissue/organ functions, and in metabolic status Examines the role of progenitor cells of different origins in the remodeling and regeneration of tissue stroma, the vasculature of blood-tissue barriers, and mucosa and external epithelium
Author : Gustav Steinhoff
Publisher : Springer Science & Business Media
ISBN 13 : 9048190754
Total Pages : 1031 pages
Book Rating : 4.51/5 ( download)
Download or read book Regenerative Medicine written by Gustav Steinhoff and published by Springer Science & Business Media. This book was released on 2011-02-04 with total page 1031 pages. Available in PDF, EPUB and Kindle. Book excerpt: Regenerative Medicine is a fastly emerging interdisciplinary field of research and clinical therapies on the repair, replacement or regeneration of cells, tissues or organs in congenital or acquired disease. This new field of research and clinical development focussing on stem cell science and regenerative biology is just starting to be the most fascinating and controversial medical development at the dawn of the 21st century. Viewing the great expectations to restructure and regenerate tissue, organs or organisms the current attempts of scientist and physicians are still in an early phase of development. This new textbook on “Regenerative Medicine – from protocol to patient” is aiming to explain the scientific knowledge and emerging technology as well as the clinical application in different organ systems and diseases. The international leading experts from four continents describe the latest scientific and clinical knowledge of the field of “Regenerative Medicine”. The process of translating science of laboratory protocols into therapies is explained in sections on basic science, clinical translation, regulatory, ethical and industrial issues. The textbook is aiming to give the student, the researcher, the health care professional, the physician, and the patient a complete survey on the current scientific basis, therapeutical protocols, clinical translation and practised therapies in Regenerative Medicine.
Author : Lucas G. Chase
Publisher : Springer Science & Business Media
ISBN 13 : 1627032002
Total Pages : 458 pages
Book Rating : 4.01/5 ( download)
Download or read book Mesenchymal Stem Cell Therapy written by Lucas G. Chase and published by Springer Science & Business Media. This book was released on 2012-12-12 with total page 458 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the past decade, significant efforts have been made to develop stem cell-based therapies for difficult to treat diseases. Multipotent mesenchymal stromal cells, also referred to as mesenchymal stem cells (MSCs), appear to hold great promise in regards to a regenerative cell-based therapy for the treatment of these diseases. Currently, more than 200 clinical trials are underway worldwide exploring the use of MSCs for the treatment of a wide range of disorders including bone, cartilage and tendon damage, myocardial infarction, graft-versus-host disease, Crohn’s disease, diabetes, multiple sclerosis, critical limb ischemia and many others. MSCs were first identified by Friendenstein and colleagues as an adherent stromal cell population within the bone marrow with the ability to form clonogenic colonies in vitro. In regards to the basic biology associated with MSCs, there has been tremendous progress towards understanding this cell population’s phenotype and function from a range of tissue sources. Despite enormous progress and an overall increased understanding of MSCs at the molecular and cellular level, several critical questions remain to be answered in regards to the use of these cells in therapeutic applications. Clinically, both autologous and allogenic approaches for the transplantation of MSCs are being explored. Several of the processing steps needed for the clinical application of MSCs, including isolation from various tissues, scalable in vitro expansion, cell banking, dose preparation, quality control parameters, delivery methods and numerous others are being extensively studied. Despite a significant number of ongoing clinical trials, none of the current therapeutic approaches have, at this point, become a standard of care treatment. Although exceptionally promising, the clinical translation of MSC-based therapies is still a work in progress. The extensive number of ongoing clinical trials is expected to provide a clearer path forward for the realization and implementation of MSCs in regenerative medicine. Towards this end, reviews of current clinical trial results and discussions of relevant topics association with the clinical application of MSCs are compiled in this book from some of the leading researchers in this exciting and rapidly advancing field. Although not absolutely all-inclusive, we hope the chapters within this book can promote and enable a better understanding of the translation of MSCs from bench-to-bedside and inspire researchers to further explore this promising and quickly evolving field.
Author : Yaoliang Tang
Publisher : Academic Press
ISBN 13 : 0128004975
Total Pages : 288 pages
Book Rating : 4.75/5 ( download)
Download or read book Mesenchymal Stem Cell Derived Exosomes written by Yaoliang Tang and published by Academic Press. This book was released on 2015-09-02 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mesenchymal stem cell-derived exosomes are at the forefront of research in two of the most high profile and funded scientific areas – cardiovascular research and stem cells. Mesenchymal Stem Cell Derived Exosomes provides insight into the biofunction and molecular mechanisms, practical tools for research, and a look toward the clinical applications of this exciting phenomenon which is emerging as an effective diagnostic. Primarily focused on the cardiovascular applications where there have been the greatest advancements toward the clinic, this is the first compendium for clinical and biomedical researchers who are interested in integrating MSC-derived exosomes as a diagnostic and therapeutic tool. Introduces the MSC-exosome mediated cell-cell communication Covers the major functional benefits in current MSC-derived exosome studies Discusses strategies for the use of MSC-derived exosomes in cardiovascular therapies
Author : Gustav Steinhoff
Publisher : Springer Science & Business Media
ISBN 13 : 9400756909
Total Pages : 1220 pages
Book Rating : 4.08/5 ( download)
Download or read book Regenerative Medicine written by Gustav Steinhoff and published by Springer Science & Business Media. This book was released on 2013-03-20 with total page 1220 pages. Available in PDF, EPUB and Kindle. Book excerpt: The field of regenerative medicine has developed rapidly over the past 20 years with the advent of molecular and cellular techniques. This textbook, Regenerative Medicine: From Protocol to Patient, aims to explain the scientific knowledge and emerging technology as well as the clinical application in different organ systems and diseases. International leading experts from four continents describe the latest scientific and clinical knowledge of the field of regenerative medicine. The process of translating science of laboratory protocols into therapies is explained in sections on regulatory, ethical and industrial issues. This textbook is organized into five parts: (I) Biology of Tissue Regeneration, (II) Stem Cell Science and Technology, (III) Tissue Engineering, Biomaterials and Nanotechnology, (IV) Regenerative Therapies and (V) Regulation and Ethics. The textbook aims to give the student, the researcher, the health care professional, the physician and the patient a complete survey on the current scientific basis, therapeutical protocols, clinical translation and practiced therapies in regenerative medicine.
Author : Ahmed El-Hashash
Publisher : Academic Press
ISBN 13 : 0128197137
Total Pages : 228 pages
Book Rating : 4.34/5 ( download)
Download or read book Mesenchymal Stem Cells in Human Health and Diseases written by Ahmed El-Hashash and published by Academic Press. This book was released on 2020-01-06 with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mesenchymal Stem Cells in Human Health and Diseases provides a contemporary overview of the fast-moving field of MSC biology, regenerative medicine and therapeutics. MSCs offer the potential to dramatically reduce human suffering from disease. Numerous MSC-based studies are ongoing each year, each offering hope for novel treatments in human disease. This book provides information on MSC application in well-studied human diseases and tissue repair/regeneration and recent advances in their research and treatment. These discoveries are placed within the structural context of tissue and developmental biology in sections dealing with recent advances in our understanding of MSC biology. Includes insights ranging from MSC biology and development through the derivation and identification and properties of MSCs Helps to identify potential innovative solutions for restoring normal morphogenesis and/or regeneration of diseased organs Discusses the fact-based promise of MSC therapeutics and regenerative medicine in the real world
Author : Guido Moll
Publisher : Frontiers Media SA
ISBN 13 : 2889636003
Total Pages : 296 pages
Book Rating : 4.06/5 ( download)
Download or read book Safety, Efficacy and Mechanisms of Action of Mesenchymal Stem Cell Therapies written by Guido Moll and published by Frontiers Media SA. This book was released on 2020-07-24 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Nagy Habib
Publisher : World Scientific
ISBN 13 : 1908979429
Total Pages : 304 pages
Book Rating : 4.21/5 ( download)
Download or read book Stem Cell Repair and Regeneration written by Nagy Habib and published by World Scientific. This book was released on 2007-03-06 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: This second book in the Stem Cell Repair and Regeneration series provides a deeper exploration of the therapeutic potential of undifferentiated human stem cells. Regenerative medicine is an extremely fast-moving field which is evolving from the initial days of hype and excitement to a more realistic appraisal of the role of stem cells in the treatment of degenerative disorders. The series aims to keep abreast of these changes by combining new knowledge in stem cell biology and therapeutic applications. The current volume contains papers by the field's leading scientists and explores the current knowledge on cell therapy for different diseases and injured organs, including diabetes, liver and heart disease. Contents:Defining Progenitors Based on Their Expression of Aldehyde Dehydrogenase (R W Storms)Fetal Mesenchymal Stem Cells are More Primitive than Adult Mesenchymal Stem Cells (C Götherström et al.)The Immunoregulatory Role of Mesenchymal Stem Cells (F Dazzi & J Timoshanko)Understanding Cell Migration Through the Paradigm of T-Lymphocyte Homing (V Mirenda & F M Marelli-Berg)Blueprint for the Response of Blood and Bone Marrow-Derived Stem Cells and Their Progeny to Hypoxia (S M Watt et al.)The Potential of Stem Cells in Tissue Engineering (N D Evans & J M Polak)Joint Tissue Engineering (C De Bari et al.)Adult Stem Cells as a Treatment for Liver Diseases (N Levičar)The Generation of Pancreatic Beta Cells from Stem Cells: Intra- and Extra-Pancreatic Sources (M Brittan et al.)Cytokines and Stem Cell Differentiation into Cardiomyocyte Lineage Cells (I Dimarakis)Regulatory Networks Controlling Neural Stem Cell Self-Renewal and Differentiation (Y Shi)Demyelination as a Therapeutic Target in Spinal Cord Injury (J R Faulkner & H S Keirstead)Microchimeric Foetal Stem Cells and Non-Invasive Prenatal Genetic Diagnosis (M A A Mikhail)The Role of Stem Cells in Liver and Gastrointestinal Cancer (M R Alison et al.)Embryonic Stem Cells: Innovation in Predictive Toxicology (G G Cezar & J Quam) Readership: Life science scientists, biomedical researchers, surgeons, clinicians, biotechnology and pharmaceutical industry professionals, postgraduate and undergraduate students. Keywords:Stem Cell;Fetal Stem Cells;Cardiac;Liver;Pancreas;HomingKey Features:Comprehensive and up-to-date overview for clinicians and scientistsContributed by leading authorities on stem cellsInformation presented in a form accessible to all interested students, clinicians and scientistsEasily accessible and richly illustrated
Author : Enrico Ragni
Publisher : Frontiers Media SA
ISBN 13 : 2889745082
Total Pages : 146 pages
Book Rating : 4.81/5 ( download)
Download or read book MSC-derived Extracellular Vesicles and Secreted Factors as ‘Cell-Free' Therapeutic Alternatives in Regenerative Medicine written by Enrico Ragni and published by Frontiers Media SA. This book was released on 2022-02-24 with total page 146 pages. Available in PDF, EPUB and Kindle. Book excerpt:
