Monoaminergic Modulation Of Cortical Excitability

Author : Kuei-Yuan Tseng
Publisher : Springer Science & Business Media
ISBN 13 : 0387722564
Total Pages : 329 pages
Book Rating : 4.66/5 ( download)

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Download or read book Monoaminergic Modulation of Cortical Excitability written by Kuei-Yuan Tseng and published by Springer Science & Business Media. This book was released on 2007-08-24 with total page 329 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive, integrated comparison of the complex modulatory action of dopamine, noradrenaline, and serotonin receptors in the cortex. The discussion assembles a range of opinions on how the monoamine systems affect cortical function. The complexity of these interactions is discussed in light of recent data showing the dramatic effect of disruption of these systems on memory formation and information processing in the cortex.

Author : Eduardo E. Benarroch
Publisher : Elsevier Health Sciences
ISBN 13 : 0750675365
Total Pages : 1110 pages
Book Rating : 4.69/5 ( download)

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Download or read book Basic Neurosciences with Clinical Applications written by Eduardo E. Benarroch and published by Elsevier Health Sciences. This book was released on 2006-01-01 with total page 1110 pages. Available in PDF, EPUB and Kindle. Book excerpt: This single-author book covers basic aspects of neuroscience, including concepts of molecular biology, neurochemistry, and electrophysiology, and makes direct clinical correlations in a concise and coherent manner. This concise, coherent text provides a link between basic science and clinical correlations.Readers will benefit from the author's expertise as an academic clinical neurologist.This text provides a concise review of basic neuroscience concepts that are included in several qualifying examinations, including the National Boards.

Author : Aaron L. Mishara
Publisher : Springer Nature
ISBN 13 : 3031383915
Total Pages : 402 pages
Book Rating : 4.15/5 ( download)

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Download or read book Phenomenological Neuropsychiatry written by Aaron L. Mishara and published by Springer Nature. This book was released on with total page 402 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Author : Virginia M. Pickel
Publisher : Elsevier
ISBN 13 : 0124186823
Total Pages : 529 pages
Book Rating : 4.28/5 ( download)

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Download or read book The Synapse written by Virginia M. Pickel and published by Elsevier. This book was released on 2013-11-16 with total page 529 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Synapse summarizes recent advances in cellular and molecular mechanisms of synaptic transmission and provides new insights into neuronal plasticity and the cellular basis of neurological diseases. Part 1 provides an in-depth look at structural differences and distribution of various pre- and post-synaptic proteins found at glutamatergic synapses. Part 2 is dedicated to dendritic spines and their associated perisynaptic glia, which together constitute the tripartite synapse. The spines are portrayed as major sites for calcium sequestration and local protein synthesis. Part 3 highlights the important regional and cellular differences between glutamatergic transmission and that of neurotransmitters such as dopamine and acetylcholine that are commonly found in axon terminals without synaptic membrane specializations. Part 4 provides an overview of the synapse from the time of formation to degeneration under the powerful influence of aging or hormonal decline that leads to severe deficits in cognitive function. Each chapter is illustrated with drawings and images derived from calcium imaging, electron microscopic immunolabeling, or electrophysiology. This book is a valuable reference for neuroscientists and clinical neurologists in both research and clinical settings. A comprehensive reference focused on the structure and function of the synapse Covers the links between the synapse and neural plasticity and the cellular basis of neurologic disease Detailed coverage of dendritic spines and associated perisynaptic glia—the tripartite synapse Includes in-depth coverage of synapse degeneration due to aging or hormonal decline related to severe cognitive impairment

Author : S. Murray Sherman
Publisher : MIT Press
ISBN 13 : 0262315009
Total Pages : 299 pages
Book Rating : 4.05/5 ( download)

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Download or read book Functional Connections of Cortical Areas written by S. Murray Sherman and published by MIT Press. This book was released on 2013-08-09 with total page 299 pages. Available in PDF, EPUB and Kindle. Book excerpt: Two leading authorities on thalamocortical connections consider how the neural circuits of the brain relate to our actions and perceptions. In this book, two leading authorities on the thalamus and its relationship to cortex build on their earlier findings to arrive at new ways of thinking about how the brain relates to the world, to cognition, and behavior. Based on foundations established earlier in their book Exploring the Thalamus and Its Role in Cortical Function, the authors consider the implications of these ground rules for thalamic inputs, thalamocortical connections, and cortical outputs. The authors argue that functional and structural analyses of pathways connecting thalamus and cortex point beyond these to lower centers and through them to the body and the world. Each cortical area depends on the messages linking it to body and world. These messages relate to the way we act and think; each cortical area receives thalamic inputs and has outputs to motor centers. Sherman and Guillery go on to discuss such topics as the role of branching axons that carry motor instructions as well as copies of these motor instructions for relay to cortex under the control of the thalamic gate. This gate allows the thalamus to control the passage of information on the basis of which cortex relates to the rest of the nervous system.

Author : Lee E. Eiden
Publisher : Academic Press
ISBN 13 : 012411539X
Total Pages : 500 pages
Book Rating : 4.92/5 ( download)

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Download or read book A New Era of Catecholamines in the Laboratory and Clinic written by Lee E. Eiden and published by Academic Press. This book was released on 2013-09-17 with total page 500 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new volume of Advances in Pharmacology presents catecholamine symposium proceedings. Chapters cover such topics as cellular dynamics of catecholamine release and re-uptake, catecholamines in mood regulation and imaging catecholamine transporters. With a variety of chapters and the best authors in the field, the volume is an essential resource for pharmacologists, immunologists and biochemists alike. Presents catecholamine symposium proceedings Chapters cover a variety of topics such as cellular dynamics of catecholamine release and re-uptake, catecholamines in mood regulation and imaging catecholamine transporters With the best authors in the field, the volume is an essential resource for pharmacologists, immunologists and biochemists alike

Author : Norbert Elsner
Publisher :
ISBN 13 :
Total Pages : 1216 pages
Book Rating : 4.70/5 ( download)

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Download or read book The Neurosciences from Basic Research to Therapy written by Norbert Elsner and published by . This book was released on 2003 with total page 1216 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Author : Leslie L. Iversen
Publisher :
ISBN 13 : 0195373030
Total Pages : 632 pages
Book Rating : 4.35/5 ( download)

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Download or read book Dopamine Handbook written by Leslie L. Iversen and published by . This book was released on 2010 with total page 632 pages. Available in PDF, EPUB and Kindle. Book excerpt: The discovery of dopamine in 1957-1958 was one of the seminal events in the development of modern neuroscience, and has been extremely important for the development of modern therapies of neurological and psychiatric disorders. Dopamine has a fundamental role in almost all aspects of behavior: from motor control to mood regulation, cognition and addiction and reward, and dopamine research has been unique within the neurosciences in the way it has bridged basic science and clinical practice. Over the decades research into the role of dopamine in health and disease has been in the forefront of modern neuroscience. The Dopamine Handbook is the first single-volume publication to capture current progress and excitement in this dynamic research field.

Author : Enrico Cherubini
Publisher : Frontiers Media SA
ISBN 13 : 2889196313
Total Pages : 167 pages
Book Rating : 4.19/5 ( download)

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Download or read book The CA3 Region of the Hippocampus: How is it? What is it for? How does it do it? written by Enrico Cherubini and published by Frontiers Media SA. This book was released on 2015-08-19 with total page 167 pages. Available in PDF, EPUB and Kindle. Book excerpt: The CA3 hippocampal region receives information from the entorhinal cortex either directly from the perforant path or indirectly from the dentate gyrus via the mossy fibers (MFs). According to their specific targets (principal/mossy cells or interneurons), MFs terminate with large boutons or small filopodial extensions, respectively. MF-CA3 synapses are characterized by a low probability of release and pronounced frequency-dependent facilitation. In addition MF terminals are endowed with mGluRs that regulate their own release. We will describe the intrinsic membrane properties of pyramidal cells, which can sometimes fire in bursts, together with the geometry of their dendritic arborization. The single layer of pyramidal cells is quite distinct from the six-layered neocortical arrangement. The resulting aligned dendrites provides the substrate for laminated excitatory inputs. They also underlie a precise, diversity of inhibitory control which we will also describe in detail. The CA3 region has an especially rich internal connectivity, with recurrent excitatory and inhibitory loops. In recent years both in vivo and in vitro studies have allowed to better understand functional properties of the CA3 auto-associative network and its role in information processing. This circuit is implicated in encoding spatial representations and episodic memories. It generates physiological population synchronies, including gamma, theta and sharp-waves that are presumed to associate firing in selected assemblies of cells in different behavioral conditions. The CA3 region is susceptible to neurodegeneration during aging and after stresses such as infection or injury. Loss of some CA3 neurones has striking effects on mossy fiber inputs and can facilitate the generation of pathologic synchrony within the CA3 micro-circuit. The aim of this special topic is to bring together experts on the cellular and molecular mechanisms regulating the wiring properties of the CA3 hippocampal microcircuit in both physiological and pathological conditions, synaptic plasticity, behavior and cognition.We will particularly emphasize the dual glutamatergic and GABAergic phenotype of MF-CA3 synapses at early developmental stages and the steps that regulate the integration of newly generated neurons into the adult dentate gyrus-CA3 circuit.

Author : Heinz Steiner
Publisher : Academic Press
ISBN 13 : 008091215X
Total Pages : 729 pages
Book Rating : 4.58/5 ( download)

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Download or read book Handbook of Basal Ganglia Structure and Function written by Heinz Steiner and published by Academic Press. This book was released on 2010-03-17 with total page 729 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Basal Ganglia comprise a group of forebrain nuclei that are interconnected with the cerebral cortex, thalamus and brainstem. Basal ganglia circuits are involved in various functions, including motor control and learning, sensorimotor integration, reward and cognition. The importance of these nuclei for normal brain function and behavior is emphasized by the numerous and diverse disorders associated with basal ganglia dysfunction, including Parkinson’s disease, Tourette’s syndrome, Huntington’s disease, obsessive-compulsive disorder, dystonia, and psychostimulant addiction. The Handbook of Basal Ganglia provides a comprehensive overview of the structural and functional organization of the basal ganglia, with special emphasis on the progress achieved over the last 10-15 years. Organized in six parts, the volume describes the general anatomical organization and provides a review of the evolution of the basal ganglia, followed by detailed accounts of recent advances in anatomy, cellular/molecular, and cellular/physiological mechanisms, and our understanding of the behavioral and clinical aspects of basal ganglia function and dysfunction. Synthesizes widely dispersed information on the behavioral neurobiology of the basal ganglia, including advances in the understanding of anatomy, cell-molecular and cell-physiological mechanisms, and behavioral/clinical aspects of function and dysfunction Features a truly international cast of the preeminent researchers in the field Fully explores the clinically relevant impact of the basal ganglia on various psychiatric and neurological diseases