Molecular Virology And Control Of Flaviviruses

Author : Pei-Yong Shi
Publisher : Caister Academic Press Limited
ISBN 13 : 9781904455929
Total Pages : 0 pages
Book Rating : 4.21/5 ( download)

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Download or read book Molecular Virology and Control of Flaviviruses written by Pei-Yong Shi and published by Caister Academic Press Limited. This book was released on 2012 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Flaviviruses are a diverse group of small RNA enveloped viruses, many of which are important human and animal pathogens. The best known include dengue virus, yellow fever virus, Japanese encephalitis virus, and West Nile virus. These viruses are endemic in many tropical and sub-tropical regions of the world. Dengue virus alone infects over 100 million people annually. In recent years, research on flaviviruses has progressed at a remarkable rate, leading to significant advances in our understanding of virus biology. This should ultimately lead to the development of better vaccine and antiviral strategies. This up-to-date and cutting-edge anthology contains contributions from the leading experts in the flavivirus field. Chapters are balanced by contributions from established investigators who have dedicated their careers to flavivirus research with those from newcomers who have recently made significant contributions to the flavivirus field. The book is divided into two sections: Molecular Virology and Virus Prevention. The first section on Molecular Virology covers: virion structure * virus replication * the NS1 glycoprotein * the NS3 protein * the NS5 protein * innate immunity and flavivirus infection * host responses to flavivirus infection * flavivirus fitness and transmission. The Virus Prevention section includes: vaccines * antibody therapy * small molecule antiviral development * flavivirus diagnostics * vector-virus interactions * vector control. The book represents an important update of flavivirus research and will serve as a reference to flavivirus researchers at the graduate level and beyond. It is a recommended text for all virology libraries.

Author :
Publisher : Elsevier
ISBN 13 : 0080493823
Total Pages : 520 pages
Book Rating : 4.24/5 ( download)

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Download or read book The Flaviviruses: Pathogenesis and Immunity written by and published by Elsevier. This book was released on 2003-12-18 with total page 520 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over 50% of known flaviviruses have been associated with human disease. The Flavivirus genus constitutes some of the most serious human pathogens including Japanese encephalitis, dengue and yellow fever. Flaviviruses are known for their complex life cycles and epidemic spread, and are considered a globally-emergent viral threat.Pathogenesis and Immunity, the second volume of The Flaviviruses, examines the processes by which the flaviviruses cause disease, the different cytopathic effects and the associated immunopathological responses produced in their hosts. * Comprehensive approach to the scientific disciplines needed to unravle the complexities of virus-host interactions.* New, detailed information on the pathogenesis and immunology of the Flavivirus family.* Descibes the technologies that have contributed to our current knowledge about the Flaviviruses.* Identifies the major problems faced in attempting to further understand the virus-host interactions that result in disease.* An exhaustive compendium of current and past knowledge on the Flavivirus family

Author :
Publisher : Elsevier
ISBN 13 : 0080493815
Total Pages : 403 pages
Book Rating : 4.17/5 ( download)

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Download or read book The Flaviviruses: Structure, Replication and Evolution written by and published by Elsevier. This book was released on 2003-12-18 with total page 403 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over 50% of known flaviviruses have been associated with human disease. The Flavivirus genus constitutes some of the most serious human pathogens including Japanese encephalitis, dengue and yellow fever. Flaviviruses are known for their complex life cycles and epidemic spread, and are considered a globally-emergent viral threat. Structure, Replication and Evolution is the first volume of The Flaviviruses and presents the latest research covering the conceptual advances on aspects such as the characterization of virus structure, cellular receptors, mechanisms of virus entry, host and viral components of the RNA replicase. Includes new, detailed information on the evolution, viral structure and replication of the Flavivirus family The only complete reference book on a major virus family Descibes the technologies that have contributed to our current knowledge about Flaviviruses Identifies the major problems faced in understanding the virus-host interactions that result in disease

Author : Matthias Kalitzky
Publisher : Taylor & Francis
ISBN 13 : 9781904933229
Total Pages : 380 pages
Book Rating : 4.2X/5 ( download)

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Download or read book Molecular Biology of the Flavivirus written by Matthias Kalitzky and published by Taylor & Francis. This book was released on 2006 with total page 380 pages. Available in PDF, EPUB and Kindle. Book excerpt: Flaviviruses constitute a family of linear, single-stranded RNA(+) viruses. They cause approximately 70 different diseases which have a major impact on national economies and health authorities worldwide. This book reviews the most significant cutting edge discoveries in the flavivirus field. Aspects of molecular biology common to flaviviruses are explored in depth. Topics include the evolution and function of flavivirus RNA, flavivirus replication, laboratory diagnosis and vaccine development. Individual chapters are devoted to the molecular biology of yellow fever virus, dengue virus, Japanese encephalitis virus, and hepatitis C virus. This book is essential for all flavivirus researchers and a recommended text for all virology laboratories.

Author : Sondra Schlesinger
Publisher : Springer Science & Business Media
ISBN 13 : 1475707851
Total Pages : 464 pages
Book Rating : 4.54/5 ( download)

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Download or read book The Togaviridae and Flaviviridae written by Sondra Schlesinger and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt: The publication of this volume of The Viruses entitled The Togaviridae and Flaviviridae comes at an appropriate time. The structure and rep lication strategies of these viruses are now known to be sufficiently di verse to warrant the removal of flaviviruses from the Togaviridae family and establish them as an independent family. Flaviviridae have a special place in the history of virology. The prototype virus-yellow fever virus was the first virus to be identified as the cause of a human disease. Some of the history of this discovery is described in Chapter 1 of this volume; in Chapter 10 the complete sequence of the RNA genome of the virus is presented. This sequence not only defines the primary structure of the viral proteins, it also clarifies the mechanism of translation of the fla vivirus genome. Knowledge of the sequence of the structural proteins of these viruses represents an important step in the potential goal of using purified flavivirus glycoproteins as vaccines. Many of the chapters in this volume focus on the structure and replication of the Togaviridae. These viruses have provided valuable models for studies in cell biology, partic ularly with regard to the cotranslational and posttranslational steps re quired for the synthesis and localization of membrane glycoproteins. Fur thermore, Togaviridae have been pivotal in our growing understanding of how enveloped viruses enter and exit from cells. The broad outlines of the structure and gene expression of Togavir idae and Flaviviridae are known, but important questions remain.

Author :
Publisher : Elsevier
ISBN 13 : 0080493831
Total Pages : 607 pages
Book Rating : 4.31/5 ( download)

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Download or read book The Flaviviruses: Detection, Diagnosis and Vaccine Development written by and published by Elsevier. This book was released on 2003-12-18 with total page 607 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over 50% of known flaviviruses have been associated with human disease. The Flavivirus genus constitutes some of the most serious human pathogens including Japanese encephalitis, dengue and yellow fever. Flaviviruses are known for their complex life cycles and epidemic spread, and are considered a globally-emergent viral threat. Detection, Diagnosis and Vaccine Development, the third volume of The Flaviviruses details the current status of technologies for detection and differentiation of these viruses, their use in surveillance and outbreak investigation, and also reviews the latest clinical research. Comprehensive approach to the scientific disciplines needed to unravle the complexities of virus-host interactions Descibes the technologies that have contributed to our current knowledge about the Flaviviruses Identifies the major problems faced in understanding the virus-host interactins that result in disease An exhaustive compendium of current and past knowledge on the Flavivirus family

Author : Nikos Vasilakis
Publisher : Caister Academic Press Limited
ISBN 13 : 9781910190210
Total Pages : 0 pages
Book Rating : 4.17/5 ( download)

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Download or read book Arboviruses written by Nikos Vasilakis and published by Caister Academic Press Limited. This book was released on 2016 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Arthropod-borne viruses (arboviruses) are the causative agents of significant morbidity and mortality among humans and domestic animals globally. They are maintained in complex biological life cycles, involving a primary vertebrate host and a primary arthropod vector. While all known arboviruses are zoonotic pathogens, their emergence as human pathogens is associated with dramatic increases of human population growth leading to uncontrolled urbanization, changes in land and water use, changes in agricultural practices, new irrigation systems and deforestation. This book brings together a panel of expert arbovirologists to produce a timely review of the rapidly expanding arbovirus research literature. In addition authors identify the most pressing questions that remain to be answered, thus providing a stimulus for future research. Topics include: taxonomy, genome organization, virus-host and virus-vector interactions, evolutionary history, role of vertical transmission in arbovirus maintenance and evolution, epidemiology, arbovirus replication, pathogenesis, arbovirus diagnostics and control, including vaccines, novel anti-viral drugs, RNA interference and genetically modified vectors. Essential reading for every arbovirologist and highly recommended for all virologists and public health officials. [Subject: Microbiology, Life Science, Arbovirology, Virology, Taxonomy, Epidemiology]

Author : ARMY MEDICAL RESEARCH INST OF INFECTIOUS DISEASES FORT DETRICK MD.
Publisher :
ISBN 13 :
Total Pages : 63 pages
Book Rating : 4.32/5 ( download)

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Download or read book International Workshop on the Molecular Biology of Flaviviruses Held at Fort Detrick, MD on 29 Nov-1 Dec 84 written by ARMY MEDICAL RESEARCH INST OF INFECTIOUS DISEASES FORT DETRICK MD. and published by . This book was released on 1985 with total page 63 pages. Available in PDF, EPUB and Kindle. Book excerpt: An International Workshop on the Molecular Biology of Flaviviruses was held. The objectives of this workshop were to examine the current status of the molecular virology of these agents and develop concepts for future flavivirus vaccine development. This document constitutes the proceedings of the symposium. Contents of this document include: Medical Importance of the Flaviviruses; Flavivirus Replication Strategy; Flavivirus Immunology - Antigen/Antibody Characterization; Future Vaccine Strategy; and Report of the Dengue Steering Committee. Originator-supplied keywords include: Flaviviridae, Flavivirus, Molecular virology, Vaccines, St. Louis encephalitis, Japanese encephalitis, Yellow fever, West Nile, Monoclonal antibody, Tick-borne encephalitis.

Author : Charles H. Calisher
Publisher : Springer Science & Business Media
ISBN 13 : 3709105722
Total Pages : 242 pages
Book Rating : 4.26/5 ( download)

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Download or read book Emergence and Control of Zoonotic Viral Encephalitides written by Charles H. Calisher and published by Springer Science & Business Media. This book was released on 2013-12-01 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this period of obvious natural emergence of viral and other diseases, it is unclear as to what diseases are emerging, why they are emerging, and what, if anything, can be done to prevent or diminish their impact. This book, a compendium of presentations made at an international meeting of experts, provides summaries of areas of concern and details as to how disease agents such as Nipah and Hendra viruses in Australasia and West Nile virus in the Americas might have suddenly appeared. Either by alterations in natural habitats and diversity or by chance, pathogens emerge from time to time. This book addresses various aspects of such emergences, such as pathogenetic mechanisms of viruses, diagnosis of viral infections, viral host-management strategies, viral genetics, vaccine development and application. It is especially valuable for laboratory virologists, disease ecologists, physicians, and those who want to understand the complexities of viral characteristics.

Author : John Mackenzie
Publisher : Springer Science & Business Media
ISBN 13 : 3642594034
Total Pages : 423 pages
Book Rating : 4.38/5 ( download)

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Download or read book Japanese Encephalitis and West Nile Viruses written by John Mackenzie and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 423 pages. Available in PDF, EPUB and Kindle. Book excerpt: Japanese encephalitis and West Nile viruses are members of the Japanese encephalitis serological group of the genus Flavivirus and therefore closely related genetically and antigenically. They share a number of properties, including the use of birds as their major wildlife maintenance host and Culicine mosquitoes for transmission, and they are both associated with severe human disease, as well as fatal infections in horses. The emergence of these two viruses, and their well-established propensity to colonise new areas, make it timely to re-examine their ecology, biology, molecular structure, replication and epidemiology, and these therefore provide the focus of this volume.