Molecular Neuropathology

Author : Gareth W. Roberts
Publisher : Cambridge University Press
ISBN 13 : 9780521425582
Total Pages : 204 pages
Book Rating : 4.81/5 ( download)

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Download or read book Molecular Neuropathology written by Gareth W. Roberts and published by Cambridge University Press. This book was released on 1995-06-08 with total page 204 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides an introduction to the essential techniques required for studying the molecular biology of brain disease. The approaches and strategies for investigations of gene structure and regulation are described with reference to the molecular genetics of prion and Alzheimer's disease. The effects of aberrant gene regulation can also be examined at the protein level by immunocytochemistry and autoradiography. Improved understanding of basic biology has resulted in new approaches to animal models using transgenic techniques and new therapeutic approaches. The volume is structured to illustrate all these approaches and demonstrate the practice and promise of molecular neuropathology.

Author : Jonas H. Ellenberg
Publisher : CRC Press
ISBN 13 : 9780824788230
Total Pages : 600 pages
Book Rating : 4.30/5 ( download)

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Download or read book Etiology of Parkinson's Disease written by Jonas H. Ellenberg and published by CRC Press. This book was released on 1995-03-01 with total page 600 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive reference provides a detailed overview of current concepts regarding the cause of Parkinson's disease-emphasizing the issues involved in the design, implementation, and analysis of epidemiological studies of parkinsonism.

Author :
Publisher : Academic Press
ISBN 13 : 0128026154
Total Pages : 640 pages
Book Rating : 4.51/5 ( download)

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Download or read book Neuropathology written by and published by Academic Press. This book was released on 2017-10-24 with total page 640 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neuropathology, Volume 145, the latest release in the Handbook of Clinical Neurology series, includes all the major topics found in a typical neuropathology text, but differentiates itself by providing a thorough overview of the morphological background of neurological disorders for researchers and clinicians who do not specialize in pathology or its clinicopathological aspects. This volume offers strong coverage of brain imaging and advances in molecular pathology and genetics, and is particularly timely given the amount of neuropathological research currently taking place. Provides a resource for the non-pathologist, aiding primary clinicians and researchers in the interpretation of patient symptoms and research findings Includes standard neuropathology, but extends to clinicopathology, imaging and molecular pathology/genetics Presents an interdisciplinary approach that can be applied in everyday clinic and research efforts

Author : Dennis Dickson
Publisher : John Wiley & Sons
ISBN 13 : 1444341235
Total Pages : 497 pages
Book Rating : 4.32/5 ( download)

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Download or read book Neurodegeneration written by Dennis Dickson and published by John Wiley & Sons. This book was released on 2011-09-09 with total page 497 pages. Available in PDF, EPUB and Kindle. Book excerpt: Most textbooks on neurodegenerative disorders have used a classification scheme based upon either clinical syndromes or anatomical distribution of the pathology. In contrast, this book looks to the future and uses a classification based upon molecular mechanisms, rather than clinical or anatomical boundaries. Major advances in molecular genetics and the application of biochemical and immunocytochemical techniques to neurodegenerative disorders have generated this new approach. Throughout most of the current volume, diseases are clustered according to the proteins that accumulate within cells (e.g. tau, α-synuclein and TDP-43) and in the extracellular compartments (e.g. β-amyloid and prion proteins) or according to a shared pathogenetic mechanism, such as trinucleotide repeats, that are a feature of specific genetic disorders. Chapters throughout the book conform to a standard lay-out for ease of access by the reader and are written by a panel of International Experts Since the first edition of this book, major advances have been made in the discovery of common molecular mechanisms between many neurodegenerative diseases most notably in the frontotemporal lobar degenerations (FTLD) and motor neuron disease or amyotrophic lateral sclerosis. This book will be essential reading for clinicians, neuropathologists and basic neuroscientists who require the firm up-to-date knowledge of mechanisms, diagnostic pathology and genetics of Neurodegenerative diseases that is required for progress in therapy and management.

Author : Meghana Chougule
Publisher : Springer Nature
ISBN 13 : 9811571260
Total Pages : 361 pages
Book Rating : 4.68/5 ( download)

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Download or read book Neuropathology of Brain Tumors with Radiologic Correlates written by Meghana Chougule and published by Springer Nature. This book was released on 2020-10-17 with total page 361 pages. Available in PDF, EPUB and Kindle. Book excerpt: This highly illustrated book explores the pathological and radiological diagnosis of various brain tumors. Featuring nearly 500 high-quality colored images, it covers MR images, intra-operative squash cytology, histopathology and immunohistochemistry microphotographs of various brain and spine tumors, including differential diagnosis, as well as the molecular diagnosis and prognosis of each tumor. The book also presents case studies of typical and rare presentations, and introduces readers to a new procedure for intra-operative cytology: the modified fields stain, which stains the slide within 2 minutes, allowing quick, accurate reporting. This book uses concise text and a consistent point-wise format that makes reading and reviewing easy. The radiological and pathological correlates of brain and spine tumors serve as a ready-reference resource for residents, surgical and neuropathologists, neuroradiologists, neurosurgeons, neuro-oncologists and research scientists.

Author : José Javier Otero
Publisher : Springer Nature
ISBN 13 : 3030691705
Total Pages : 266 pages
Book Rating : 4.07/5 ( download)

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Download or read book Precision Molecular Pathology of Glioblastoma written by José Javier Otero and published by Springer Nature. This book was released on 2021-04-30 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides a balanced and realistic review of the current state of glioblastoma, ranging from traditional histological review, molecular pathology of glioma, modern radiomics, neurosurgical focus, and integration of treatment plans by neuro-oncologists. The book reviews basic principles such as epidemiology and etiology, and modern 2016 WHO classification of CNS tumors. Chapters cover a general overview of common molecular techniques used in molecular pathology, molecular pathology in a developing country, key drivers of patient outcomes and predictors of response to radiation and/or chemotherapy treatment, and immunohistochemical surrogates for key molecular pathology. It concludes with reviews on radiomics, animal and stem cell models of glioblastoma, and a chapter on the emerging field of Glioblastoma Neuroscience. Precision Molecular Pathology of Glioblastoma is intended for pathology residents and fellows interested in glioblastoma, general surgical pathologists who need reviews on how to implement modern glioblastoma classification, as well as neuro-radiologists, oncologists, and radiation oncologists needing a holistic perspective to glioblastoma diagnosis and management.

Author : Gabor G. Kovacs
Publisher : Cambridge University Press
ISBN 13 : 1316337650
Total Pages : 320 pages
Book Rating : 4.53/5 ( download)

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Download or read book Neuropathology of Neurodegenerative Diseases written by Gabor G. Kovacs and published by Cambridge University Press. This book was released on 2017-12-13 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: This practical guide to the diagnosis of neurodegenerative diseases discusses modern molecular techniques, morphological classification, fundamentals of clinical symptomology, diagnostic pitfalls and immunostaining protocols. It is based on the proteinopathy concept of neurodegenerative disease, which has influenced classification and provides new strategies for therapy. Numerous high-quality images, including histopathology photomicrographs and neuroradiology scans, accompany the description of morphologic alterations and interpretation of immunoreactivities. Diagnostic methods and criteria are placed within recent developments in neuropathology, including the now widespread application of immunohistochemistry. To aid daily practice, the guide includes diagnostic algorithms and offers personal insights from experienced experts in the field. Special focus is given to the way brain tissue should be handled during diagnosis. This is a must-have reference for medical specialists and specialist medical trainees in the fields of pathology, neuropathology and neurology working with neuropathologic features of neurodegenerative diseases.

Author : Alan Nelson Davison
Publisher : Igaku-Shoin Medical Publishers
ISBN 13 :
Total Pages : 716 pages
Book Rating : 4.94/5 ( download)

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Download or read book The Molecular Basis of Neuropathology written by Alan Nelson Davison and published by Igaku-Shoin Medical Publishers. This book was released on 1981 with total page 716 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Author : Peter Davies
Publisher : Cold Spring Harbor Laboratory Press
ISBN 13 :
Total Pages : 506 pages
Book Rating : 4.23/5 ( download)

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Download or read book Molecular Neuropathology of Aging written by Peter Davies and published by Cold Spring Harbor Laboratory Press. This book was released on 1987 with total page 506 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Author : B.K. Kleinschmidt-DeMasters
Publisher : Elsevier Health Sciences
ISBN 13 : 0323713319
Total Pages : 900 pages
Book Rating : 4.13/5 ( download)

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Download or read book Diagnostic Pathology: Neuropathology E-Book written by B.K. Kleinschmidt-DeMasters and published by Elsevier Health Sciences. This book was released on 2022-02-07 with total page 900 pages. Available in PDF, EPUB and Kindle. Book excerpt: Covering all aspects of neuropathology, this updated volume in the Diagnostic Pathology series is an excellent point-of-care resource for pathologists at all levels of experience and training—both as a quick reference and as an efficient review to improve knowledge and skills. The third edition is an easy-to-use, one-stop reference for the most recent clinical, pathological, histological, and molecular knowledge in the field. It offers complete information on lesions of the brain, sellar region, and peripheral nerves, as well as benign cysts and selected infectious, inflammatory, reactive, vascular, and cortical dysplastic lesions, enabling you to arrive at the correct diagnosis and prepare actionable, useful reports. Incorporates new WHO Classification of Tumors of the Central Nervous System, 5th Edition Offers information on neoplasms of the brain, sellar region, and peripheral nerves, as well as benign cysts and selected infectious, inflammatory, reactive, and vascular lesions, aiding you in arriving at the correct diagnosis Emphasizes surgical pathology but also provides significant content on nonneoplastic diseases that present with focal lesions, especially those that are potentially misinterpreted as neoplasms Contains a detailed molecular diagnostics chapter with a section on methylation profiling, which has become indispensable as a method of tumor classification Features new and updated chapters detailing several types of tumors that have been reclassified due to recent molecular driver information, cIMPACT-NOW recommendations, and the WHO Classification, 5th Edition