Molecular Imaging Of Neurodegenerative Disorders

Author : Donna J. Cross
Publisher : Springer Nature
ISBN 13 : 3031350987
Total Pages : 340 pages
Book Rating : 4.86/5 ( download)

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Download or read book Molecular Imaging of Neurodegenerative Disorders written by Donna J. Cross and published by Springer Nature. This book was released on 2023-09-26 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive review of the role of molecular imaging in neurodegenerative diseases. A growing field, molecular imaging of neurodegeneration is becoming increasingly relevant with an aging population, and this book serves to provide both an introduction to the concept and background of neurodegeneration and an update on the most recent imaging advances. Throughout, chapters will review current applications of neuroimaging in neurodegenerative disorders, like dementia and movement disorders, and increase knowledge of quantification and semi-quantification methods for neuroimaging. Imaging methods such as PET/CT and PET/MR are covered, as well as more advanced technologies like artificial intelligence algorithms and novel radiotracers. Chapters are also intended to improve competency in reporting and interpretation skills with structured information on current practice. The book concludes with a collection of up to date practice cases for the interpretation of neurodegeneration in nuclear medicine imaging. This is an ideal guide for nuclear medicine physicians, neuroradiologists, neurologists, residents, trainees, and related medical professionals caring for patients with neurodegeneration.

Author : Luca Saba
Publisher : OUP Oxford
ISBN 13 : 0191651400
Total Pages : 640 pages
Book Rating : 4.03/5 ( download)

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Download or read book Imaging in Neurodegenerative Disorders written by Luca Saba and published by OUP Oxford. This book was released on 2015-01-08 with total page 640 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diagnosing neurodegenerative diseases can prove particularly intimidating to clinicians, because many times the diagnosis cannot be critically "confirmed" by a simple test. New imaging modalities have advanced to the point of high resolution, morphological, metabolic and functional analysis. Computed tomography, magnetic resonance, nuclear medicine and molecular imaging have recently emerged as outstanding non-invasive techniques for the study of the neurodegenerative disorders. Imaging in Neurodegenerative Disorders covers all the imaging techniques and new exciting methods like new tracers, biomarker, metabolomic and gene-array profiling, potential for applying such techniques clinically, and offers present and future applications as applied to the neurodegenerative disorders with the most world renowned scientists in these fields. This book is an invaluable resource for researchers, clinicians, and trainees in neuroscience, neurology, psychiatry, and radiology.

Author : Sangam G. Kanekar
Publisher : Thieme
ISBN 13 : 1604068558
Total Pages : 1574 pages
Book Rating : 4.59/5 ( download)

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Download or read book Imaging of Neurodegenerative Disorders written by Sangam G. Kanekar and published by Thieme. This book was released on 2015-11-05 with total page 1574 pages. Available in PDF, EPUB and Kindle. Book excerpt: The definitive reference on imaging and diagnosis of neurodegenerative diseases FIVE STARS from Doody's Star Ratings™ Imaging of Neurodegenerative Disorders is a comprehensive, up-to-date reference covering the latest techniques used in neuroimaging as well as the basic structural imaging that facilitates diagnosis of various neurodegenerative disorders. All advanced imaging modalities, including MR spectroscopy, DTI, MRI, and PET scans, are discussed in detail, enabling readers to gain a solid understanding of how to use them to diagnose neurodegenerative diseases. Key Features: Each chapter covers the clinical features, pathology, and imaging of a specific disease/disorder Sections on cerebellar degeneration and dysfunction, motor neuron disorders, post-traumatic cognitive disorders, dementia with extrapyramidal syndromes, and deep brain stimulation A final section discusses the distinctions between preventable, potentially reversible, and irreversible dementia This book provides radiologists and all who care for patients suffering from neurodegenerative diseases with an invaluable reference that will be part of their medical library for many years to come.

Author : Patricia A. Broderick
Publisher : Springer Science & Business Media
ISBN 13 : 1592598889
Total Pages : 313 pages
Book Rating : 4.85/5 ( download)

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Download or read book Bioimaging in Neurodegeneration written by Patricia A. Broderick and published by Springer Science & Business Media. This book was released on 2007-11-05 with total page 313 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bioimaging is in the forefront of medicine for the diagnosis and helps to predict the progression of AD via mild cognitive treatment of neurodegenerative disease. Conventional magnetic impairment (MCI) studies. resonance imaging (MRI) uses interactive external magnetic fields Novel neuroimaging technologies, such as neuromolecular and resonant frequencies of protons from water molecules. imaging (NMI) with a series of newly developed BRODERICK ® However, newer sequences, such as magnetization-prepared rapid PROBE sensors, directly image neurotransmitters, precursors, acquisition gradient echo (MPRAGE), are able to seek higher and metabolites in vivo, in real time and within seconds, at separate levels of anatomic resolution by allowing more rapid temporal and selective waveform potentials. NMI, which uses an imaging. Magnetic resonance spectroscopy (MRS) images electrochemical basis for detection, enables the differentiation of metabolic changes, enabling underlying pathophysiologic neurodegenerative diseases in patients who present with mesial dysfunction in neurodegeneration to be deciphered. Neuro- versus neocortical temporal lobe epilepsy. In fact, NMI has some 1 chemicals visible with proton H MRS include N-acetyl aspartate remarkable similarities to MRI insofar as there is technological (NAA), creatine/phosphocreatine (Cr), and choline (Cho); NAA dependence on electron and proton transfer, respectively, and is considered to act as an in vivo marker for neuronal loss and/or further dependence is seen in both NMI and MRI on tissue neuronal dysfunction. By extending imaging to the study of composition such as lipids.

Author : Rudi A.J.O. Dierckx
Publisher : Springer
ISBN 13 : 3642543073
Total Pages : 1103 pages
Book Rating : 4.74/5 ( download)

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Download or read book PET and SPECT in Neurology written by Rudi A.J.O. Dierckx and published by Springer. This book was released on 2014-06-02 with total page 1103 pages. Available in PDF, EPUB and Kindle. Book excerpt: PET and SPECT in Neurology highlight the combined expertise of renowned authors whose dedication to the investigation of neurological disorders through nuclear medicine technology has achieved international recognition. Classical neurodegenerative disorders are discussed as well as cerebrovascular disorders, brain tumors, epilepsy, head trauma, coma, sleeping disorders and inflammatory and infectious diseases of the CNS. The latest results in nuclear brain imaging are detailed. Most chapters are written jointly by a clinical neurologist and a nuclear medicine specialist to ensure a multidisciplinary approach. This state-of-the-art compendium will be valuable not only to neurologists and radiologists/nuclear medicine specialists but also to interested general practitioners and geriatricians. It is the second volume of a trilogy on PET and SPECT imaging in the neurosciences, the other volumes covering PET and SPECT in psychiatry and in neurobiological systems.

Author : Michael J. Welch
Publisher : CRC Press
ISBN 13 : 1439841950
Total Pages : 390 pages
Book Rating : 4.52/5 ( download)

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Download or read book Targeted Molecular Imaging written by Michael J. Welch and published by CRC Press. This book was released on 2012-02-24 with total page 390 pages. Available in PDF, EPUB and Kindle. Book excerpt: Targeted Molecular Imaging covers the development of novel diagnostic approaches that use an imaging probe and agent to noninvasively visualize cellular processes in normal and disease states. It discusses the concept, development, preclinical studies, and, in many cases, translation to the clinic of targeted imaging agents. The many case studies that form the core of this book deal with the development and translation of non-nuclear probes and radiotracers; other sections address critical topics such as In vitro studies, small animal research, and the application of targeted probes for nuclear, optical and MRI imaging. The chapters use a common format to demonstrate how various investigators approach the comprehensive task of validating a new targeted probe. Targeted Molecular Imaging is a timely resource for a rapidly advancing field, and addresses: Various methods of validating a new targeted probe through examples from human studies with imaging of breast cancer, cardiovascular disease, and neurodegenerative diseases Basic principles, disease models, imaging studies in animals, imaging in initial human studies, and the application of molecular imaging in pharmacy and drug discovery In vitro studies, small animal studies, and targeted radiopharmaceuticals Using these case studies, investigators can generalize and apply the information to their own specific targeted probe. The insights provided by the contributors, experts who have developed these approaches in their own groups, help guide scientists planning to translate imaging agents from the concept stage to clinical application.

Author : Marios Politis
Publisher : Academic Press
ISBN 13 : 0128154217
Total Pages : 275 pages
Book Rating : 4.12/5 ( download)

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Download or read book Imaging in Movement Disorders: Imaging Applications in Non-Parkinsonian and Other Movement Disorders written by Marios Politis and published by Academic Press. This book was released on 2018-11-21 with total page 275 pages. Available in PDF, EPUB and Kindle. Book excerpt: Imaging in Movement Disorders: Imaging in Other Movement Disorders and Dementia, Volume 143 provides an up-to-date textbook on the use of imaging modalities across the spectrum of movement disorders and dementias. The book brings together lessons learned from neuroimaging tools in the content of movement disorders, including idiopathic and sporadic forms of Parkinson’s disease, Huntington’s disease, Atypical Parkinsonism, Dystonia, Essential Tremor, and more. Specific chapters cover Neuroimaging Applications in Dystonia, Neuroimaging Applications in Essential Tremor, Neuroimaging applications in Restless Leg Syndrome, Neuroimaging Application in Tourette's Syndrome and TIC Disorders, Neuroimaging Applications in Functional Movement Disorders, and Neuroimaging Applications in Cerebellar Disorders. Addition sections cover Molecular Imaging of Parkinson's Disease Cognitive Impairment, Structural MRI in Parkinson's Disease Cognitive Impairment, Functional MRI in Parkinson's Disease Cognitive Impairment, Molecular Imaging of Dementia with Lewy Bodies, Structural and Functional MRI of Dementia with Lewy Bodies, Transcranial Sonography in Movement Disorders, Imaging transplantation in Movement Disorders, Hybrid PET-MRI Applications in Movement Disorders, amongst other topics. Offers a complete review of the application of neuroimaging tools in Dystonia, Essential Tremor, Restless Leg Syndrome, Tourette’s syndrome, and Tic and Movement Disorders Covers the role of neuroimaging research in movement disorder dementias Presents the importance of imaging techniques as biomarkers of disease progression and treatment response in therapeutic trials

Author : Frederik Barkhof
Publisher : Springer Science & Business Media
ISBN 13 : 3642008186
Total Pages : 295 pages
Book Rating : 4.84/5 ( download)

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Download or read book Neuroimaging in Dementia written by Frederik Barkhof and published by Springer Science & Business Media. This book was released on 2011-02-11 with total page 295 pages. Available in PDF, EPUB and Kindle. Book excerpt: This up-to-date, superbly illustrated book is a practical guide to the effective use of neuroimaging in the patient with cognitive decline. It sets out the key clinical and imaging features of the various causes of dementia and directs the reader from clinical presentation to neuroimaging and on to an accurate diagnosis whenever possible. After an introductory chapter on the clinical background, the available "toolbox" of structural and functional neuroimaging techniques is reviewed in detail, including CT, MRI and advanced MR techniques, SPECT and PET, and image analysis methods. The imaging findings in normal ageing are then discussed, followed by a series of chapters that carefully present and analyze the key findings in patients with dementias. Throughout, a practical approach is adopted, geared specifically to the needs of clinicians (neurologists, radiologists, psychiatrists, geriatricians) working in the field of dementia, for whom this book will prove an invaluable resource.

Author : Rathan Subramaniam
Publisher : Elsevier Health Sciences
ISBN 13 : 0323227368
Total Pages : 110 pages
Book Rating : 4.60/5 ( download)

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Download or read book Novel Imaging Techniques in Neurodegenerative and Movement Disorders, An Issue of PET Clinics written by Rathan Subramaniam and published by Elsevier Health Sciences. This book was released on 2013-10-28 with total page 110 pages. Available in PDF, EPUB and Kindle. Book excerpt: Edited by leaders of the field, Rathan Subramaniam from Johns Hopkins and Jorge Barrio from UCLA, this issue of PET Clinics focuses on the evolving role of novel imaging techniques in negenerative and movement disorders common in the aged population.

Author :
Publisher : Academic Press
ISBN 13 : 0128151420
Total Pages : 422 pages
Book Rating : 4.26/5 ( download)

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Download or read book Imaging in Movement Disorders: Imaging in Atypical Parkinsonism and Familial Movement Disorders written by and published by Academic Press. This book was released on 2018-11-05 with total page 422 pages. Available in PDF, EPUB and Kindle. Book excerpt: Imaging in Movement Disorders: Imaging in Atypical Parkinsonism and Familial Movement Disorders, Volume 142, addresses the use of imaging modalities across the spectrum of movement disorders and dementias. Over the last decades, advances in neuroimaging tools have played a pivotal role in expanding our understanding of disease aetiology and pathophysiology, identifying biomarkers to monitor disease progression, aiding differential diagnosis and in the identification of novel targets for therapeutic intervention. This updated volume covers PET Molecular Imaging in Atypical Parkinsonism, SPECT Molecular Imaging in Atypical Parkinsonism, Structural MRI in Atypical Parkinsonism, Functional MRI in Atypical Parkinsonism, and more. Offers a complete review of the applications of neuroimaging tools in Atypical Parkinsonism, familial Parkinson’s disease and Huntington’s disease Discusses the role of neuroimaging modalities, including SPECT, PET, and structural and functional MRI Includes sections on potential clinical applications and future directions