Molecular Epidemiology

Author : Paul A. Schulte
Publisher : Academic Press
ISBN 13 : 0323138578
Total Pages : 609 pages
Book Rating : 4.74/5 ( download)

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Download or read book Molecular Epidemiology written by Paul A. Schulte and published by Academic Press. This book was released on 2012-12-02 with total page 609 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book will serve as a primer for both laboratory and field scientists who are shaping the emerging field of molecular epidemiology. Molecular epidemiology utilizes the same paradigm as traditional epidemiology but uses biological markers to identify exposure, disease or susceptibility. Schulte and Perera present the epidemiologic methods pertinent to biological markers. The book is also designed to enumerate the considerations necessary for valid field research and provide a resource on the salient and subtle features of biological indicators.

Author : Paul A. Schulte
Publisher : Academic Press
ISBN 13 : 0126323461
Total Pages : 613 pages
Book Rating : 4.67/5 ( download)

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Download or read book Molecular Epidemiology written by Paul A. Schulte and published by Academic Press. This book was released on 1998-02-20 with total page 613 pages. Available in PDF, EPUB and Kindle. Book excerpt: This groundbreaking work, now available in paperback, has helped to shape the emerging discipline of molecular epidemiology. Molecular Epidemiology has proven useful to epidemiologists unfamiliar with the terminology and techniques of molecular biology as well as to the molecular biologist working to understand the determinants of human disease and to use that information to control disease. This book demonstrates how molecular epidemiology utilizes the same paradigm as traditional epidemiology in addition to using biological markers to identify exposure, disease, or susceptibility.

Author : Chris Wild
Publisher : John Wiley & Sons
ISBN 13 : 1119965616
Total Pages : 435 pages
Book Rating : 4.19/5 ( download)

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Download or read book Molecular Epidemiology of Chronic Diseases written by Chris Wild and published by John Wiley & Sons. This book was released on 2011-09-09 with total page 435 pages. Available in PDF, EPUB and Kindle. Book excerpt: "I think this is an excellent book–I recommend it to anyone involved in molecular epidemiology... The 26 chapters are written by topic specialists, in an explanatory, east to read style." –BTS Newsletter, Summer 2009 "This text provides an accessible and useful handbook for the epidemiologist who wants to survey the field, to become better informed, to look at recent developments and get some background on these or simply to appreciate further the relatively rapid changes in informatic and analytical technologies which increasingly will serve and underpin future epidemiological studies. One of the strengths in this book is the extensive array of practical illustrative examples, and it would also in my opinion have useful potential as a teaching text." –American Journal of Human Biology, March 2009 With the sequencing of the human genome and the mapping of millions of single nucleotide polymorphisms, epidemiology has moved into the molecular domain. Scientists can now use molecular markers to track disease-associated genes in populations, enabling them to study complex chronic diseases that might result from the weak interactions of many genes with the environment. Use of these laboratory generated biomarker data and an understanding of disease mechanisms are increasingly important in elucidating disease aetiology. Molecular Epidemiology of Disease crosses the disciplinary boundaries between laboratory scientists, epidemiologists, clinical researchers and biostatisticians and is accessible to all these relevant research communities in focusing on practical issues of application, rather than reviews of current areas of research. Covers categories of biomarkers of exposure, susceptibility and disease Includes chapters on novel technologies: genomics, transcriptomics, proteomics and metabonomics, which are increasingly finding application in population studies Emphasizes new statistical and bioinformatics approaches necessitated by the large data sets generated using these new methodologies Demonstrates the potential applications of laboratory techniques in tackling epidemiological problems while considering their limitations, including the sources of uncertainty and inaccuracy Discusses issues such as reliability (compared to traditional epidemiological methods) and the timing of exposure Explores practical elements of conducting population studies, including biological repositories and ethics Molecular Epidemiology of Disease provides an easy-to-use, clearly presented handbook that allows epidemiologists to understand the specifics of research involving biomarkers, and laboratory scientists to understand the main issues of epidemiological study design and analysis. It also provides a useful tool for courses on molecular epidemiology, using many examples from population studies to illustrate key concepts and principles.

Author : Juan Carlos Gomez-Verjan
Publisher : Springer
ISBN 13 : 9783030409579
Total Pages : 0 pages
Book Rating : 4.70/5 ( download)

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Download or read book Clinical Genetics and Genomics of Aging written by Juan Carlos Gomez-Verjan and published by Springer. This book was released on 2021-04-14 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The world population is rapidly aging—it is estimated that by 1950, around 17% of the population will be elderly. In this context, aging involves several physiological, psychological and highly complex social processes that vary from one person to another. For a long time, medical care for older adults has focused on treating chronic, age-related diseases and their associated consequences. Recently, biomedical research brings a novel point of view to develop more effective interventions by targeting the aging process itself rather than separate conditions. There is a growing number of reports indicating that aging is driven by several interconnected mechanisms and biological components referred to as the molecular pillars of aging. Interfering with these mechanisms could help to treat, prevent, and understand the development of age-related diseases and associated syndromes. This book provides a clinical perspective and general update on biomedical and genetic research in aging, moving from an update in the molecular pillars of aging to a perspective of the most recent pharmacological, clinical, and diagnostic applications using genomic approaches and techniques. While this book focuses on the specifics of genetics and genomics, it also adopts a clinical perspective of geroscience, which seeks to understand the genetic, molecular and cellular mechanisms that make aging an important risk factor and, sometimes, a determining factor in the diseases and common chronic conditions of older people. Additionally, Clinical Genetics and Genomics of Aging is a significant contribution to support aging research, as it shows that collaboration across disciplines is relevant to progress in the field. As more and more people benefit from increased longevity, clinician and researchers will be empowered by this knowledge to contribute to the progress of aging research.

Author : Patricia A. Buffler
Publisher : IARC Scientific Publications
ISBN 13 :
Total Pages : 464 pages
Book Rating : 4.62/5 ( download)

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Download or read book Mechanisms of Carcinogenesis written by Patricia A. Buffler and published by IARC Scientific Publications. This book was released on 2004 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt: During the last two decades, molecular epidemiology has become an important discipline in cancer research. It has evolved towards the development, validation and application of markers of susceptibility and, more recently, markers of mechanisms of cancer development. This volume on mechanisms of carcinogenesis covers from an interdisciplinary perspective, the contribution of molecular epidemiology to the understanding of mechanisms of carcinogenesis, and represents a further contribution to the development of molecular epidemiology as a major cancer research domain.

Author : Palmer, Lyle J.
Publisher : Policy Press
ISBN 13 : 1861348975
Total Pages : 240 pages
Book Rating : 4.75/5 ( download)

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Download or read book An Introduction to Genetic Epidemiology written by Palmer, Lyle J. and published by Policy Press. This book was released on 2011-05-31 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book brings together leading experts to provide an introduction to genetic epidemiology that begins with a primer in human molecular genetics through all the standard methods in population genetics and genetic epidemiology required for an adequate grounding in the field.

Author : Andreas Ziegler
Publisher : John Wiley & Sons
ISBN 13 : 3527633669
Total Pages : 522 pages
Book Rating : 4.61/5 ( download)

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Download or read book A Statistical Approach to Genetic Epidemiology written by Andreas Ziegler and published by John Wiley & Sons. This book was released on 2011-08-24 with total page 522 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Statistical Approach to Genetic Epidemiology After studying statistics and mathematics at the University of Munich and obtaining his doctoral degree from the University of Dortmund, Andreas Ziegler received the Johann-Peter-Süssmilch-Medal of the German Association for Medical Informatics, Biometry and Epidemiology for his post-doctoral work on “Model Free Linkage Analysis of Quantitative Traits” in 1999. In 2004, he was one of the recipients of the Fritz-Linder-Forum-Award from the German Association for Surgery.

Author : International Agency for Research on Cancer
Publisher : IARC Scientific Publications
ISBN 13 : 9789283221630
Total Pages : 0 pages
Book Rating : 4.3X/5 ( download)

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Download or read book Molecular Epidemiology written by International Agency for Research on Cancer and published by IARC Scientific Publications. This book was released on 2011 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular epidemiology has taken advantage of the emergence of technological advances collectively identified as "-omics" (genomics, transcriptomics, proteomic, metabonomics) and their usage in epidemiological studies has heralded a revolution in the design implementation, and interpretation of studies on disease causation. Not the least, molecular epidemiology has brought together scientists of all disciplines to interact into very large, often multi-national networks, fostering consortia that have the size and power to address diseases as a global challenge. This book captures these fascinating developments and provides an extended, forward-looking vision of the principles, practice and impact of molecular epidemiology. Written and coordinated by world leaders in the field, the book covers, in a systematic way, the major conceptual advances, with a strong emphasis on study design and on how to incorporate biomarker studies into epidemiology practice. While providing a cornerstone for specialists, the book is also a teaching and training manual for public health, biology and medical students at the undergraduate, graduate, and post-graduate levels. With its strong insistence on interdisciplinarity and its focus on translating complex concepts into information that can be shared across the borders of scientific disciplines, the book will be a door-opener for researchers whose work is being attracted by the potent magnet of molecular epidemiology.

Author : Muin J. Khoury
Publisher : Monographs in Epidemiology and
ISBN 13 : 0195052889
Total Pages : 394 pages
Book Rating : 4.86/5 ( download)

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Download or read book Fundamentals of Genetic Epidemiology written by Muin J. Khoury and published by Monographs in Epidemiology and. This book was released on 1993 with total page 394 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text integrates the principles, methods and approaches of epidemiology and genetics in the study of disease aetiology. The authors define the central theme of genetic epidemiology as the study of the role of genetic factors and their interaction with environmental factors in the occurrence of disease in populations.

Author : Betsy Foxman
Publisher : Academic Press
ISBN 13 : 9780128102312
Total Pages : 350 pages
Book Rating : 4.14/5 ( download)

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Download or read book Molecular Tools and Infectious Disease Epidemiology written by Betsy Foxman and published by Academic Press. This book was released on 2017-11-13 with total page 350 pages. Available in PDF, EPUB and Kindle. Book excerpt: The application of modern molecular genetic and biologic techniques to infectious disease epidemiology dramatically improves measurement of disease and putative risk factors, increasing our ability to detect and track outbreaks, identify risk factors and detect new infectious agents. However, integration of these techniques into epidemiologic studies also poses new challenges in the design, conduct, and analysis. We examine these opportunities and methodologic challenges giving specific examples. The book will be written for the reader with limited understanding of genetics, biology and epidemiology. Presents the key points of consideration when integrating molecular biology and epidemiologyDiscusses how using molecular tools in epidemiologic research affects program design and conductConsiders the ethical concerns that arise in molecular epidemiologic studiesProvides a context for understanding and interpreting scientific literature as a foundation for subsequent practical experience in the laboratory and in the field