Molecular Diagnosis And Targeting For Thoracic And Gastrointestinal Malignancy

Author : Yutaka Shimada
Publisher : Springer
ISBN 13 : 9811064695
Total Pages : 156 pages
Book Rating : 4.92/5 ( download)

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Download or read book Molecular Diagnosis and Targeting for Thoracic and Gastrointestinal Malignancy written by Yutaka Shimada and published by Springer. This book was released on 2017-11-29 with total page 156 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume focuses on the clinical applications of molecular diagnosis and targeted therapy from the viewpoint of oncologists specializing in specific organs. In addition, it discusses the role of molecular diagnosis and targeted therapy in the course of surgical treatment. Recent, rapid advances in molecular biology have shed new light on the mechanisms of cancer progression, and molecularly targeted drugs have been used to treat a variety of malignant diseases. For the diagnosis and precise treatment of cancer, analysis of the molecular background of the tumor is indispensable. However, there are both tumor-specific and comprehensive mechanisms involved in these processes. Accordingly, a firm grasp of molecular diagnosis and targeted therapies for different tumors is vital for clinicians and basic researchers alike. This book provides essential information and the latest findings on molecular diagnosis and targeted therapy for thoracic and gastrointestinal malignancies. Though primarily intended for clinical and basic oncologists, it also offers a useful guide for clinicians who are interested in this field and are considering getting started in molecular diagnosis and targeted therapy.

Author : Takashi Nakano
Publisher : Springer Nature
ISBN 13 : 981159158X
Total Pages : 352 pages
Book Rating : 4.87/5 ( download)

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Download or read book Malignant Pleural Mesothelioma written by Takashi Nakano and published by Springer Nature. This book was released on 2021-02-05 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides essential information on recent advances in molecular genetics, epidemiology, translational research, and the latest results of clinical trials on mesothelioma. Significant progress has been made in understanding mesothelioma biology, and in developing new therapies for this refractory tumor, malignant pleural mesothelioma (MPM). Not only does this volume summarize the latest research-based data on the disease; it also shares insights into future research directions. The book consists of 5 themed sections on: epidemiology, pathogenesis, screening and early detection, molecular genetics, and clinical aspects and management. Several chapters focus on new trends in the field, e.g. immune therapy and identification of biomarkers, molecular oncogenesis including genetic susceptibility, and molecular diagnostic pathology. The book also highlights new cancer treatment approaches, such as immunotherapy based on immune checkpoint inhibitors, which has meant a paradigm shift in other types of cancer, and given some hope to MPM patients. In turn, it discusses recent molecular pathological studies on mesothelioma, which claim to offer more accurate classifications than traditional morphology and immunohistochemistry-based approaches. All of these cutting-edge analyses provide the basis for a closing discussion on future developments and research directions. Malignant Pleural Mesothelioma - Advances in Pathogenesis, Diagnosis, and Treatments has been edited and authored by respected researchers and will be of interest to medical, surgical and radiation oncologists; pulmonologists; pathologists and basic researchers alike. Since the disease represents a significant diagnostic and therapeutic challenge, scientists and clinicians from learners to experts, as well as fellows in training in these subspecialties, will value this book.

Author : Zsolt Kovacs
Publisher : Frontiers Media SA
ISBN 13 : 2832526373
Total Pages : 682 pages
Book Rating : 4.78/5 ( download)

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Download or read book Advanced Molecular Targets in the Diagnosis and Treatment of Gastrointestinal Cancers written by Zsolt Kovacs and published by Frontiers Media SA. This book was released on 2023-06-05 with total page 682 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gastrointestinal cancers are among the most common cancer types, based on the Cancer Genome Atlas. GI cancers are within the most frequent malignancy, with almost 150.000 new cases in 2020. On one hand a big number of researches are focused on the diagnosis, new diagnostic approaches in upper and lower gastrointestinal tract cancers. On the other hand in the last 10 years several papers had been published about the possible therapeutic targets, pointing to precision and personalized medicine.

Author : Stephanie Green
Publisher : CRC Press
ISBN 13 : 1439814481
Total Pages : 266 pages
Book Rating : 4.82/5 ( download)

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Download or read book Clinical Trials in Oncology, Third Edition written by Stephanie Green and published by CRC Press. This book was released on 2012-05-09 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt: The third edition of the bestselling Clinical Trials in Oncology provides a concise, nontechnical, and thoroughly up-to-date review of methods and issues related to cancer clinical trials. The authors emphasize the importance of proper study design, analysis, and data management and identify the pitfalls inherent in these processes. In addition, the book has been restructured to have separate chapters and expanded discussions on general clinical trials issues, and issues specific to Phases I, II, and III. New sections cover innovations in Phase I designs, randomized Phase II designs, and overcoming the challenges of array data. Although this book focuses on cancer trials, the same issues and concepts are important in any clinical setting. As always, the authors use clear, lucid prose and a multitude of real-world examples to convey the principles of successful trials without the need for a strong statistics or mathematics background. Armed with Clinical Trials in Oncology, Third Edition, clinicians and statisticians can avoid the many hazards that can jeopardize the success of a trial.

Author : D. J. Th. Wagener
Publisher : Bohn Stafleu van Loghum
ISBN 13 : 9789031361434
Total Pages : 318 pages
Book Rating : 4.37/5 ( download)

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Download or read book The History of Oncology written by D. J. Th. Wagener and published by Bohn Stafleu van Loghum. This book was released on 2009-07-13 with total page 318 pages. Available in PDF, EPUB and Kindle. Book excerpt: ‘The story of oncology is not only fascinating but also contains many accounts of dead ends, chance discoveries, illusions, mistakes and disappointments alongside the few successes.’These words are taken from the introduction to this book. The author, professor emeritus of Medical Oncology, reviews all aspects of the problem of cancer from a historical perspective, from the oldest existing records to the latest scientific and medical advances. It will interest the many people engaged in the treatment of cancer to read how the current therapeutic methods came about, and the book may also provide inspiration for cancer researchers, and for all those directly or indirectly involved with cancer. The layman looking for background information on a particular treatment may find it useful too. The various chapters can be read independently. A glossary and a few explanatory diagrams augment the text.This book grew out of an invitation the author received to lecture on the history of oncology. During his background reading, he discovered that there was no single volume dealing with the entire history of the subject. Fortunately, however, a great deal of information could be found here and there in the literature. As he read, he was struck by the fascinating stories behind many discoveries, and felt impelled to put them together in a single comprehensive account. The results of his labors are presented in this remarkable volume.The author, Prof. D.J.Th. (Theo) Wagener, was head of the department of Medical Oncology at the Radboud University Nijmegen Medical Centre in the Netherlands from 1982 to 2001, chairman of the Educational Committee of the European Society of Medical Oncology (ESMO), a member of the Educational Committee of the American Society of Clinical Oncology (ASCO) and a member of various international scientific working groups, mainly of the European Organization for Research and Treatment of Cancer (EORTC).

Author : W. H. O. Classification WHO Classification of Tumours Editorial Board
Publisher :
ISBN 13 : 9789283245063
Total Pages : 500 pages
Book Rating : 4.67/5 ( download)

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Download or read book Thoracic Tumours written by W. H. O. Classification WHO Classification of Tumours Editorial Board and published by . This book was released on 2021-04-21 with total page 500 pages. Available in PDF, EPUB and Kindle. Book excerpt: ****When not purchasing directly from the official sales agents of the WHO, especially at online bookshops, please note that there have been issues with counterfeited copies. Buy only from known sellers and if there are quality issues, please contact the seller for a refund.***** Thoracic Tumoursis the fifth available volume in the fifth edition of the WHO series on the classification of human tumours. This series (also known as the WHO Blue Books) is regarded as the gold standard for the diagnosis of tumours and comprises a unique synthesis of histopathological diagnosis with digital and molecular pathology. These authoritative and concise reference books provide indispensable international standards for anyone involved in the care of patients with cancer or in cancer research, underpinning individual patient treatment as well as research into all aspects of cancer causation, prevention, therapy, and education. What's new in this edition? The fifth edition, guided by the WHO Classification of Tumours Editorial Board, establishes a single coherent cancer classification presented across a collection of individual volumes organized on the basis of anatomical site (digestive system, breast, soft tissue and bone, etc.) and structured in a systematic manner, with each tumour type listed within a taxonomic classification: site, category, family (class), type, and subtype. In each volume, the entities are now listed from benign to malignant and are described under an updated set of headings, including histopathology, diagnostic molecular pathology, staging, and easy-to-read essential and desirable diagnostic criteria. Who should read this book? * Pathologists * Oncologists * Respiratory physicians * Thoracic radiologists * Cancer researchers * Surgeons * Epidemiologists * Cancer registrars This volume: * Prepared by 217 authors and editors * Contributors from around the world * More than 1000 high-quality images * More than 3500 references

Author : International Agency for Research on Cancer
Publisher : World Health Organization
ISBN 13 : 9789283224365
Total Pages : 410 pages
Book Rating : 4.61/5 ( download)

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Download or read book Who Classification of Tumours of the Lung, Pleura, Thymus and Heart written by International Agency for Research on Cancer and published by World Health Organization. This book was released on 2015-03-16 with total page 410 pages. Available in PDF, EPUB and Kindle. Book excerpt: WHO Classification of Tumours of the Lung, Pleura, Thymus and Heart is the seventh volume in the Fourth Edition of the WHO series on histological and genetic typing of human tumors. This authoritative, concise reference book provides an international standard for oncologists and pathologists and will serve as an indispensable guide for use in the design of studies monitoring response to therapy and clinical outcome.

Author : Prateek Sharma
Publisher : John Wiley & Sons
ISBN 13 : 1405171537
Total Pages : 312 pages
Book Rating : 4.33/5 ( download)

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Download or read book Barrett's Esophagus and Esophageal Adenocarcinoma written by Prateek Sharma and published by John Wiley & Sons. This book was released on 2008-04-15 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: The leading reference text entirely devoted to this increasinglysignificant condition This text is dedicated to Barrett’s esophagus and providesrecent evidence and current approaches to patient management. Ithas been completely revised, updated and extended to include thelatest research findings and describes how these affect day-to-dayclinical practice. It includes seven new chapters and even more color images thanthe last edition. Each chapter, written by the leadinginternational experts in the field, provides clear, didacticguidance on diagnosis, treatment and management of thiscondition. Barrett’s Espohagus gives an extensive overviewcovering epidemiology, screening, pathology, gastroenterology andsurgery. It looks at the precursor lesions leading to thedevelopment of Barrett’s epithelium, the uniquecharacteristics of Barrett’s esophagus, and the consequencesof malignant degeneration. All aspects of diagnosis, secondaryprevention, multimodality, and medical and surgical treatment areclearly explained. This is a complete guide on the latest thinking on diagnosis andtreatment of Barrett’s esophagus which can be referred toover and over again.

Author : Wataru Walter Sutow
Publisher :
ISBN 13 :
Total Pages : 982 pages
Book Rating : 4.21/5 ( download)

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Download or read book Clinical Pediatric Oncology written by Wataru Walter Sutow and published by . This book was released on 1984 with total page 982 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Author : Mahdi Rezai
Publisher : Springer Nature
ISBN 13 : 3030731472
Total Pages : 665 pages
Book Rating : 4.72/5 ( download)

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Download or read book Breast Cancer Essentials written by Mahdi Rezai and published by Springer Nature. This book was released on 2021-08-27 with total page 665 pages. Available in PDF, EPUB and Kindle. Book excerpt: Breast cancer is a disease requiring multidisciplinary management including surgery, medical and radiation oncology, radiology, pathology, nuclear medicine, genetic counseling, and psychological support. Each member of the team needs to be updated continuously on breast cancer treatment because of its rapidly changing nature. From the diagnostic procedures to operations and even in metastatic stages of breast cancer, surgeons play an essential part in multidisciplinary teams. After standard surgical options, oncoplastic breast surgery is rapidly becoming one of the most important surgical topics that should be learned by attending surgeons. The idea of writing this book stemmed from a collaboration between the European Academy of Senology (EAoS), European Institute of Oncology (IEO), Euro-Asian Society of Mastology (ESOMA), and SENATURK (Turkish Academy of Senology), which have been working together to promote better training in breast care for professionals. The book offers invaluable support for breast surgeons by covering critical and essential information in senology. It will also greatly benefit the other members of multidisciplinary teams, surgery residents, gynecologists, and plastic and reconstructive surgeons.