Molecular Biology Of The Hepatitis B Virus

Author : Alan McLachlan
Publisher : CRC Press
ISBN 13 : 1351091654
Total Pages : 308 pages
Book Rating : 4.57/5 ( download)

DOWNLOAD NOW!

Download or read book Molecular Biology of the Hepatitis B Virus written by Alan McLachlan and published by CRC Press. This book was released on 2018-05-04 with total page 308 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular Biology of the Hepatitis B Virus presents a comprehensive account of the various molecular aspects of the life cycle of the hepatitis B virus (HBV). Topics covered include the animal model systems, sequence data on the hepadnavirus genomes, the transcripts coded for the biral genome and sequence elements involved in regulating their expression, hepadnavirus replication, and analysis of the various HBV gene products and their role in virion synthesis and assembly. Other important features of the book include its discussions of the consequences of long term exposure to hepadnavirus infection and its association with hepatocellular carcinoma, the use of recombinant technologies in the generation of second generation vaccines, and the utilization of recombinant technologies to analyze an immune mediated disease. Researchers studying hepadnaviruses will find a wealth of information in this essential reference volume.

Author : Haitao Guo
Publisher : Humana
ISBN 13 : 9781071640265
Total Pages : 0 pages
Book Rating : 4.67/5 ( download)

DOWNLOAD NOW!

Download or read book Hepatitis B Virus written by Haitao Guo and published by Humana. This book was released on 2024-08-28 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This detailed new edition collects state-of-the-art methods in the fields of hepatitis B virus (HBV) molecular biology and immunology. The book features techniques for cell culture, epigenetic regulation of cccDNA transcription, epitranscriptomic modification of HBV RNA, HBV pregenomic RNA and subviral particle morphogenesis, and much more. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Hepatitis B Virus: Methods and Protocols, Second Edition serves as an ideal guide for researchers pursuing a cure for this chronic disease.

Author : J Monjardino
Publisher : World Scientific
ISBN 13 : 1783262605
Total Pages : 148 pages
Book Rating : 4.01/5 ( download)

DOWNLOAD NOW!

Download or read book Molecular Biology of Human Hepatitis Viruses written by J Monjardino and published by World Scientific. This book was released on 1998-05-30 with total page 148 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hepatitis A and B viruses have infected nearly half the current world population; and as many as 500 million people are still infected with the hepatitis B or C virus today. Hepatitis B vaccination is effective but not universally adopted and no vaccine is available against hepatitis C. Treatment is prohibitively expensive for areas of high endemicity or prevalence and not universally effective. This important and timely book covers recent advances in understanding the molecular biology of hepatitis viruses. The advances have contributed new insights into the molecular mechanisms involved in replication of genetic information and in gene expression; and have translated into diagnostics; prevention and development of antiviral drugs. Contents:Hepatitis A VirusHepatitis B VirusHepatitis Delta VirusHepatitis C VirusHepatitis E VirusOther Hepatitis-Associated Viruses: HGV/GBC Readership: Graduate students; virologists (medical/non-medical) and molecular biologists. Keywords:Viral Hepatitis;Hepatitis A;Hepatitis B;Hepatitis C;Hepatitis D;Delta Virus;Non-A Non-B Hepatitis;Hepatocellular Carcinoma;Viral CarcinogenesisReviews: “It is a sound accompaniment to a focussed lecture; a bookshelf reference on this group of viruses in one volume; but moreover; a detailed introduction to the nucleic acid arrangements of these diverse pathogens.” Australian Journal of Medical Science “This book provides a good introduction and foundation for the study of this disparate group of viruses and the low price will make it readily accessible to students of microbiology; virology and medicine.” Microbiology Today

Author : Irwin M. Arias
Publisher : John Wiley & Sons
ISBN 13 : 1119436826
Total Pages : 1156 pages
Book Rating : 4.29/5 ( download)

DOWNLOAD NOW!

Download or read book The Liver written by Irwin M. Arias and published by John Wiley & Sons. This book was released on 2020-03-09 with total page 1156 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bridging the gap between basic scientific advances and the understanding of liver disease — the extensively revised new edition of the premier text in the field. The latest edition of The Liver: Biology and Pathobiology remains a definitive volume in the field of hepatology, relating advances in biomedical sciences and engineering to understanding of liver structure, function, and disease pathology and treatment. Contributions from leading researchers examine the cell biology of the liver, the pathobiology of liver disease, the liver’s growth, regeneration, metabolic functions, and more. Now in its sixth edition, this classic text has been exhaustively revised to reflect new discoveries in biology and their influence on diagnosing, managing, and preventing liver disease. Seventy new chapters — including substantial original sections on liver cancer and groundbreaking advances that will have significant impact on hepatology — provide comprehensive, fully up-to-date coverage of both the current state and future direction of hepatology. Topics include liver RNA structure and function, gene editing, single-cell and single-molecule genomic analyses, the molecular biology of hepatitis, drug interactions and engineered drug design, and liver disease mechanisms and therapies. Edited by globally-recognized experts in the field, this authoritative volume: Relates molecular physiology to understanding disease pathology and treatment Links the science and pathology of the liver to practical clinical applications Features 16 new “Horizons” chapters that explore new and emerging science and technology Includes plentiful full-color illustrations and figures The Liver: Biology and Pathobiology, Sixth Edition is an indispensable resource for practicing and trainee hepatologists, gastroenterologists, hepatobiliary and liver transplant surgeons, and researchers and scientists in areas including hepatology, cell and molecular biology, virology, and drug metabolism.

Author : M. Feitelson
Publisher : Springer Science & Business Media
ISBN 13 : 1461325730
Total Pages : 283 pages
Book Rating : 4.34/5 ( download)

DOWNLOAD NOW!

Download or read book Molecular Components of Hepatitis B Virus written by M. Feitelson and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 283 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the discovery of Australia antigen and its association with type B hepatitis, molecular characterization of the components making up hepatitis B virus (RBV) have been pursued with worldwide interest. Over the past two decades, such characterization has led to the development of sensitive assays to screen and exclude contaminated units from blood banks and has recently resulted in the licensing of several RBV vaccines. That more than 200 million people worldwide are chronically infected with RBV, and that they are at a high risk for the development of chronic hepatitis and hepatocellular carcinoma, still represent formidable problems in our understanding of host-virus relationships on the molecular level. In the absence of a suitable tissue culture system, and with a very limited host range of infection, characterization of RBV on the molecular level has made remarkable progress recently with the advent of genome cloning, sequencing and expression of individual virus genes by recombinant DNA technology. The presence of hepatitis B-like viruses in an expanding number of animal hosts, and the possibility of virus replication in cells other than hepatocytes, provide great promise that future work will elucidate the molecular mechanisms operative in the various outcomes of RBV infection.

Author : Wolfgang Helmut Caselmann
Publisher : World Scientific
ISBN 13 : 1783262737
Total Pages : 342 pages
Book Rating : 4.31/5 ( download)

DOWNLOAD NOW!

Download or read book Hepatitis B Virus: Molecular Mechanisms In Disease And Novel Strategies For Therapy written by Wolfgang Helmut Caselmann and published by World Scientific. This book was released on 1998-06-30 with total page 342 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book covers both the molecular aspects of hepatitis B virus replication and gene expression in vivo and in model systems, and the clinical impact of genetic variants or immunological response in chronic infection. Major emphasis is laid on the molecular mechanisms underlying hepatitis B virus-associated liver carcinogenesis and their possible relevance to therapy and to the prevention of infection. Rational approaches to design novel vaccines or cytokine treatments, as well as strategies to develop vectors for liver-directed gene therapy, are discussed.

Author : Isa K. Mushahwar
Publisher : Gulf Professional Publishing
ISBN 13 : 9780444514875
Total Pages : 298 pages
Book Rating : 4.72/5 ( download)

DOWNLOAD NOW!

Download or read book Viral Hepatitis Molecular Biology Diagnosis and Control written by Isa K. Mushahwar and published by Gulf Professional Publishing. This book was released on 2004 with total page 298 pages. Available in PDF, EPUB and Kindle. Book excerpt: The last forty years have witnessed the discovery of five human hepatitis viruses: hepatitis virus A, B, C, D, and E, and two related blood-borne viruses: GB virus C and TT virus. Viral Hepatitis provides a comprehensive overview of the latest developments and research studies in human viral hepatitis. Written by leading international scientists in the field, this book covers topics ranging from the history of these viruses to their molecular biology, diagnosis, epidemiology and control. It will be an invaluable reference source for hepatitis researchers, reference and diagnostic laboratories, clinicians, public health officers and graduate and medical students. Book jacket.

Author : Hong Tang
Publisher : Springer Nature
ISBN 13 : 9811391513
Total Pages : 190 pages
Book Rating : 4.14/5 ( download)

DOWNLOAD NOW!

Download or read book Hepatitis B Virus Infection written by Hong Tang and published by Springer Nature. This book was released on 2019-11-18 with total page 190 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides a state-of-the-art review of the key aspects of HBV. It covers our current understanding of the HBV genome and lifecycle, liver-enriched factors in the regulation of HBV transcription and translation, HBV protein structures and biological functions, and the immunology and pathogenesis of HBV. It also provides an update on cell and animal models, as well as molecular approaches. The respective chapters also cover the clinical management of hepatitis B and discuss future research directions, in particular, the identification of molecular targets for pharmacological intervention. Given its scope, the book offers a valuable resource for students, researchers, clinicians, and health practitioners in the fields of virology, infectious disease, public health etc. Dr Hong Tang is a Professor and Director of the Center of Infectious Diseases, West China Hospital of Sichuan University.

Author : Jing-Hsiung James Ou
Publisher : Springer Science & Business Media
ISBN 13 : 1461508819
Total Pages : 293 pages
Book Rating : 4.16/5 ( download)

DOWNLOAD NOW!

Download or read book Hepatitis Viruses written by Jing-Hsiung James Ou and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 293 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hepatitis viruses research started more than fifty years ago. The names of hepatitis A and hepatitis B were introduced in 1947 when it became clear that there were two types of hepatitis that were transmitted either enterically or parenterally. It became apparent in the 1970's that there were additional hepatitis viruses distinct from hepatitis A and hepatitis B, and thus, the term non-A, non-B hepatitis was introduced. The non-A, non-B hepatitis was further divided into post-transfusion non-A, non-B hepatitis and enterically-transmitted non-A, non-B hepatitis in the 1980's. By the end of the 1980's, both post-transfusion non-A, non-B virus and enterically-transmitted non-A, non-B virus had been identified and renamed hepatitis C virus and hepatitis E virus, respectively. Hepatitis delta antigen was first recognized as an antigen associated with hepatitis B virus infection in the 1970's. In the early 1980's, a virus was isolated and named hepatitis delta virus. These five different hepatitis viruses have distinct replication pathways and are major health concerns. They have become an important topic for teaching to graduate-level and medical students. Hepatitis Viruses provides a comprehensive, up-to-date review of these viruses to readers. Each chapter is written by one of the top researchers in the field, and topics include: the epidemiology and the natural history of infection of these viruses, the molecular biology and the replication cycle of individual hepatitis viruses, host-virus interactions and the pathogenesis of hepatitis viruses, the immunology of hepatitis viruses, the relationship between hepatitis viruses and hepatocellular carcinoma, the viral vaccines and antiviral drugs. This book can serve as a supplemental reading material to graduate students and medical students, and to any researcher who would like to learn more about hepatitis viruses.

Author : William S. Mason
Publisher : Springer Science & Business Media
ISBN 13 : 3642760155
Total Pages : 212 pages
Book Rating : 4.50/5 ( download)

DOWNLOAD NOW!

Download or read book Hepadnaviruses written by William S. Mason and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 212 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pioneering work on hepatitis B virus and hepatitis delta virus, and the discovery of hepatitis B-like virus in animals during the 1970's has been followed, over the past ten years, by an explosion of interest in how these viruses replicate, maintain chronic infections, and cause liver disease and hepatocellular carcinoma. The purpose of this book is two-fold. First, the authors of each chapter provide a summary of their specialty that will not only serve as an introduction, but will also provide the newcomer to hepatitis B virology with up-to-date information and insights into the goals and accomplishments of each area of investigation. Second, since the diversification of interests and increased specialization of hepadnaviruses researchers has reached a level where it is no longer possible for any one individual to read all the primary literature, this book will help to refocus interest on what is, after all, the major objective: to understand and ultimately treat or prevent chronic liver disease and liver cancer. Accordingly, chapters are included which span a range of interests, from the management of hepatitis B patients to new approaches to antiviral therapy, from the role of hepadnavirus gene expression in DNA replication to the role of ribozymes in the delta virus life cycle, from liver cancer in naturally infected woodchucks to liver disease in HBV transgenic mice to the use of hepatitis virus vectors to treat inherited enzyme deficiencies.