Molecular Basis Of Thyroid Hormone Action

Author : Jack Oppenheimer
Publisher : Elsevier
ISBN 13 : 0323147453
Total Pages : 515 pages
Book Rating : 4.53/5 ( download)

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Download or read book Molecular Basis of Thyroid Hormone Action written by Jack Oppenheimer and published by Elsevier. This book was released on 2012-12-02 with total page 515 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular Basis of Thyroid Hormone Action focuses on the actions of thyroid hormones in eukaryotic cells. This book discusses the profound effects of thyroid hormones on the growth, development, and metabolism of practically all tissues of higher organisms. Organized into 15 chapters, this volume starts with an overview of the kinetic interrelationships of hormone bound to specific receptors and hormone associated with other tissue and plasma pools in living animals. This book then discusses the thyroid hormone receptor, a chromatin-associated protein that appears to mediate the actions of the thyroid hormones in mammalian cells. Other chapters consider the localization of the receptors in chromatin. This book further discusses how thyroid hormones stimulate the accumulation of specific mRNA molecules in cell culture as well as in tissues in vivo. This book is intended for readers who are interested in cell and molecular biology. Endocrinologists will also find this book extremely useful.

Author :
Publisher : Academic Press
ISBN 13 : 0128141174
Total Pages : 564 pages
Book Rating : 4.75/5 ( download)

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Download or read book Thyroid Hormone written by and published by Academic Press. This book was released on 2018-01-18 with total page 564 pages. Available in PDF, EPUB and Kindle. Book excerpt: Thyroid hormone, Volume 106, the latest release in the Vitamins and Hormones series first published in 1943 provides up-to-date information on crystal structures and basic structural studies on neurotrophins and their receptors, neurotrophin functions and the biological actions of neurotrophins related to clinical conditions and disease. This new release focuses on timely topics, including the Nuclear Import and Export of the Thyroid Hormone Receptor, the Thyroid hormone and the white matter of the central nervous system: from development to repair, Thyroid hormone and astrocyte differentiation, and the Molecular Basis of Nongenomic Actions of Thyroid Hormone, amongst other topics. Presents the latest information on thyroid hormone Provides a long-running series that focuses on updates and advances in vitamins and hormones Covers single molecules or diseases that are related to vitamins or hormones, with the topic broadly interpreted to include related substances

Author : NADIR R. FARID
Publisher : Springer Science & Business Media
ISBN 13 : 1402081073
Total Pages : 441 pages
Book Rating : 4.71/5 ( download)

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Download or read book Molecular Basis of Thyroid Cancer written by NADIR R. FARID and published by Springer Science & Business Media. This book was released on 2006-02-03 with total page 441 pages. Available in PDF, EPUB and Kindle. Book excerpt: - This series is indexed in index Medicus - The turn around time for this series is fast, making the research as accurate as a journal

Author : Antonino Belfiore
Publisher : Springer
ISBN 13 : 9783319446745
Total Pages : 0 pages
Book Rating : 4.46/5 ( download)

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Download or read book Principles of Endocrinology and Hormone Action written by Antonino Belfiore and published by Springer. This book was released on 2018-02-08 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides comprehensive coverage of the current knowledge of the physiology of the endocrine system and hormone synthesis and release, transport, and action at the molecular and cellular levels. It presents essential as well as in-depth information of value to both medical students and specialists in Endocrinology, Gynecology, Pediatrics, and Internal Medicine. Although it is well established that the endocrine system regulates essential functions involved in growth, reproduction, and homeostasis, it is increasingly being recognized that this complex regulatory system comprises not only hormones secreted by the classic endocrine glands but also hormones and regulatory factors produced by many organs, and involves extensive crosstalk with the neural and immune system. At the same time, our knowledge of the molecular basis of hormone action has greatly improved. Understanding this complexity of endocrine physiology is crucial to prevent endocrine disorders, to improve the sensitivity of our diagnostic tools, and to provide the rationale for pharmacological, immunological, or genetic interventions. It is such understanding that this book is designed to foster.

Author : Choh Hao Li
Publisher : Elsevier
ISBN 13 : 0323162983
Total Pages : 463 pages
Book Rating : 4.82/5 ( download)

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Download or read book Thyroid Hormones written by Choh Hao Li and published by Elsevier. This book was released on 1978-01-01 with total page 463 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hormonal Proteins and Peptides, Volume VI: Thyroid Hormones is a compilation of papers that details the various aspects, chemical properties, effects, and history of thyroid hormones. The book covers a wide range of topics related to the study of thyroid hormones. Six chapters are devoted to the various aspects of thyroid hormones. Chapter 1 deals with the chemistry of human thyrotropin. Chapters 2 and 3 survey the chemistry of thyroid hormones and analogs, focusing on synthesis and structure-activity relationships. Chapter 4 presents thyroxin action and the possible direct participation of thyroxin in catecholamine pathways in the nervous system. Chapter 5 discusses the thyroid hormone action during amphibian metamorphosis at the cellular and molecular levels. An account of the evolution of the thyroid function is given in Chapter 6. The final chapter delves on the historical aspect of thyroid hormones. Biochemists, physicians, pharmacologists, researchers, and students in the medical field will benefit from this book.

Author : Noriyuki Koibuchi
Publisher : Springer
ISBN 13 : 1493937375
Total Pages : 207 pages
Book Rating : 4.70/5 ( download)

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Download or read book Thyroid Hormone Disruption and Neurodevelopment written by Noriyuki Koibuchi and published by Springer. This book was released on 2016-11-11 with total page 207 pages. Available in PDF, EPUB and Kindle. Book excerpt: Thyroid hormone plays an important role in development and functional maintenance in the central nervous system. Deficiency of thyroid hormone during fetal and early postnatal life induces abnormal development known as cretinism in humans. However, the molecular mechanism of thyroid hormone action has not yet been fully understood. Thyroid hormone action in the brain may be disrupted under various pathological conditions. In addition, environmental factors including endocrine-disrupting chemicals and bacterial endotoxins may disrupt thyroid hormone action in brain, causing abnormal brain development and functional disruption. This is a first book to comprehensively describe the effect of thyroid hormone disruption in the central nervous system. The first section deals with the disruption of thyroid hormone action at the molecular level. First the authors provide a summary of the possible molecular mechanisms of thyroid hormone action in the brain, then they discuss several factors that may disrupt thyroid hormone action. In the second section, animal models to study thyroid hormone action will be introduced. An interesting character of thyroid hormone deficiency is that, without thyroid hormone, the thyroid hormone receptor may act as a “repressor” of gene expression, causing more severe consequence than those of thyroid hormone receptor knockout animals. Thus, several different kind of animal models may be used to clarify the role of thyroid hormone and its receptor in the brain. In the third section, human studies on thyroid disease and neurodevelopment will be introduced. Although endemic cretinism induced by iodine deficiency and sporadic cretinism by various thyroid mutation are well known, the pathophysiological mechanisms that create each abnormal phenotype are not fully understood. ​

Author : John A.H. Wass
Publisher : Oxford University Press, USA
ISBN 13 : 0199235295
Total Pages : 2158 pages
Book Rating : 4.92/5 ( download)

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Download or read book Oxford Textbook of Endocrinology and Diabetes written by John A.H. Wass and published by Oxford University Press, USA. This book was released on 2011-07-28 with total page 2158 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now in its second edition, the Oxford Textbook of Endocrinology and Diabetes is a fully comprehensive, evidence-based, and highly-valued reference work combining basic science with clinical guidance, and providing first rate advice on diagnosis and treatment.

Author : Richard E. Brown
Publisher : Cambridge University Press
ISBN 13 : 9780521426657
Total Pages : 434 pages
Book Rating : 4.50/5 ( download)

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Download or read book An Introduction to Neuroendocrinology written by Richard E. Brown and published by Cambridge University Press. This book was released on 1994-01-27 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is designed as an introductory text in neuroendocrinology; the study of the interaction between the brain and endocrine system and the influence of this on behaviour. The endocrine glands, pituitary gland and hypothalamus and their interactions and hormones are discussed. The action of steroid and thyroid hormone receptors and the regulation of target cell response to hormones is examined. The function of neuropeptides is discussed with respect to the neuroendocrine system and behaviour. The neuroimmune system and lymphokines are described and the interaction between the neuroendocrine and neuroimmune systems discussed. Finally, methods for studying hormonal influences on behaviour are outlined. Each chapter has review and essay questions designed for advanced students and honours or graduate students with a background in neuroscience, respectively.

Author : G. Szinnai
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3318027219
Total Pages : 262 pages
Book Rating : 4.11/5 ( download)

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Download or read book Paediatric Thyroidology written by G. Szinnai and published by Karger Medical and Scientific Publishers. This book was released on 2014-09-15 with total page 262 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents a comprehensive overview of pediatric thyroid diseases and thus provides a useful tool for clinical problem solving. Opinion leaders in the field present reviews on all relevant diseases of the hypothalamic-pituitary-thyroid axis. Sixteen chapters cover topics ranging from fetal thyroidology, congenital hypothyroidism, central hypothyroidism, inherited defects of thyroid hormone action, cell transport and metabolism to iodine deficiency, autoimmune thyroid disease and thyroid tumors. Written by clinicians, the chapters provide in-depth information and current guidelines for clinical problems encountered in pediatric thyroidology. As a unique feature, a case seminar collection for each chapter presents typical patient histories providing key learning points and key references for clinical problem solving in family medicine, pediatric endocrinology and medical genetics. Providing a succinct update on clinical pediatric thyroidology, this book is an essential tool for pediatric and adult endocrinologists, as well as for general practitioners, pediatricians and medical geneticists.

Author : Alexander von Zur Mühlen
Publisher :
ISBN 13 :
Total Pages : 248 pages
Book Rating : 4.36/5 ( download)

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Download or read book Biochemical Basis of Thyroid Stimulation and Thyroid Hormone Action written by Alexander von Zur Mühlen and published by . This book was released on 1976 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt: