Mitochondrial Function Part B

Author :
Publisher : Academic Press
ISBN 13 : 9780080923505
Total Pages : 450 pages
Book Rating : 4.0X/5 ( download)

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Download or read book Mitochondrial Function, Part B written by and published by Academic Press. This book was released on 2009-05-05 with total page 450 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this second of two new volumes covering mitochondria, methods developed to assess the number and function of nuclear-encoded proteins in the mitochondrion are presented. Chapters focus on the regulation of mitochondrial function and mitochondrial diseases, with a section emphasizing the mitochondrial defects associated with type 2 diabetes. The critically acclaimed laboratory standard for 40 years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. With more than 450 volumes published, each volume presents material that is relevant in today's labs -- truly an essential publication for researchers in all fields of life sciences. New methods focusing on the examination of normal and abnormal mitochondrial function are presented in an easy-to-follow format by the researchers who developed them Along with a companion volume covering topics including mitochondrial electron transport chain complexes and reactive oxygen species, provides a comprehensive overview of modern techniques in the study of mitochondrial malfunction Provides a "one-stop shop" for tried and tested essential techniques, eliminating the need to wade through untested or unreliable methods

Author : Carla Koehler
Publisher : Springer Science & Business Media
ISBN 13 : 9783540214892
Total Pages : 362 pages
Book Rating : 4.95/5 ( download)

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Download or read book Mitochondrial Function and Biogenesis written by Carla Koehler and published by Springer Science & Business Media. This book was released on 2004-05-13 with total page 362 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides the first modern and truly comprehensive coverage of the biochemistry, genetics, and pathology of mitochondria in different organisms. It particularly focuses on the recent advances in our understanding of basic mitochondrial research to the consequences of dysfunction at the molecular level. (Cover)

Author : Bruce Alberts
Publisher :
ISBN 13 : 9780815332183
Total Pages : 0 pages
Book Rating : 4.81/5 ( download)

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Download or read book Molecular Biology of The Cell written by Bruce Alberts and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Author : H. Tedeschi
Publisher : Springer Science & Business Media
ISBN 13 : 3709184126
Total Pages : 291 pages
Book Rating : 4.27/5 ( download)

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Download or read book Mitochondria: Structure, Biogenesis and Transducing Functions written by H. Tedeschi and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 291 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the past few years, the body of experimental work on the structure, function and assembly processes of mitochondria has expanded rapidly. No one person can believe himself or herself completely in control of the burgeoning literature without possessing serious omissions or blind spots. In the present monograph I have attempted a critical evaluation of the literature. I believe that the common thread of single authorship outweighs the shortcomings of one person presenting many disparate viewpo,ints. It is my hope that the end product represents a comprehensive and coordinated review of the subject matter to the present date. Although the bulk of this monograph was completed by October 1974, I have made some attempts to update several of the sections at later times. Albany, N. Y. , November 1975 H. TEDESCHI Contents A. Structure of Mitochondria 1. General Organization . a) Conventional Thin Section Electron Microscopy b) Negative Staining Techniques . 3 c) Freeze-Cleavage . . . . . . . 4 2. Special Organization and Inclusions 10 a) Prismatic or Atypical Cristae 10 b) Filaments and Tubules . . 11 c) Amorphous Inclusions 12 d) Intramitochondrial Granules 12 e) DNA Containing Fibers 14 3. Topography of the Mitochondrial Transducing Systems 15 B. The Assembly of Mitochondria 18 1. Mitochondrial DNA and Its Genetic Role 19 2. Transcription of the Mitochondrial DNA . 28 a) mRNA . . . . . . . . . . . . . . 30 b) The Machinery for Transcription and Translation 32 c) Turnover of Mitochondrial RNA 36 3. Protein Synthesis . . . . . . . . 37 a) Mitochondrial Protein Synthesis and Its Characteristics 37 b) Role of Mitochondrial Protein Synthesis . .

Author : Anna Gvozdjáková
Publisher : Springer Science & Business Media
ISBN 13 : 1402067143
Total Pages : 446 pages
Book Rating : 4.43/5 ( download)

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Download or read book Mitochondrial Medicine written by Anna Gvozdjáková and published by Springer Science & Business Media. This book was released on 2008-02-01 with total page 446 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mitochondrial medicine deals with diseases that are related to mitochondrial dysfunction due to a number of causes from free radical damage to genetic mutation. This book is based on extensive data gathered over 30 years of clinical and experimental research. In it, internationally recognized authors share their experience in various fields of their expertise and guide readers through the disease process, from basic biochemical mechanisms to diagnosis to therapeutic aspects.

Author :
Publisher : Academic Press
ISBN 13 : 0080915337
Total Pages : 502 pages
Book Rating : 4.33/5 ( download)

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Download or read book Mitochondrial Function, Part A written by and published by Academic Press. This book was released on 2009-04-03 with total page 502 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first of two new volumes covering mitochondria, Mitochondrial Function, Part A presents modern methods that have been developed to examine mitochondrial electron transport chain complexes, iron-sulfur proteins and reactive oxygen species. These new techniques provide investigators with sensitive, original approaches to the study of disease states associated with mitochondrial malfunction. The critically acclaimed laboratory standard for 40 years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. With more than 400 volumes published, each Methods in Enzymology volume presents material that is relevant in today's labs -- truly an essential publication for researchers in all fields of life sciences. New methods focusing on the examination of normal and abnormal mitochondrial function are presented in an easy-to-follow format by the researchers who developed them Along with companion volume covering mitochondrial diseases and defects, provides a comprehensive overview of modern techniques in the study of mitochondrial malfunction Provides a "one-stop shop" for tried and tested essential techniques, eliminating the need to wade through untested or unreliable methods

Author : Lawrence H. Lash
Publisher : Elsevier
ISBN 13 : 1483218619
Total Pages : 527 pages
Book Rating : 4.18/5 ( download)

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Download or read book Mitochondrial Dysfunction written by Lawrence H. Lash and published by Elsevier. This book was released on 2013-10-22 with total page 527 pages. Available in PDF, EPUB and Kindle. Book excerpt: Methods in Toxicology, Volume 2: Mitochondrial Dysfunction provides a source of methods, techniques, and experimental approaches for studying the role of abnormal mitochondrial function in cell injury. The book discusses the methods for the preparation and basic functional assessment of mitochondria from liver, kidney, muscle, and brain; the methods for assessing mitochondrial dysfunction in vivo and in intact organs; and the structural aspects of mitochondrial dysfunction are addressed. The text also describes chemical detoxification and metabolism as well as specific metabolic reactions that are especially important targets or indicators of damage. The methods for measurement of alterations in fatty acid and phospholipid metabolism and for the analysis and manipulation of oxidative injury and antioxidant systems are also considered. The book further tackles additional methods on mitochondrial energetics and transport processes; approaches for assessing impaired function of mitochondria; and genetic and developmental aspects of mitochondrial disease and toxicology. The text also looks into mitochondrial DNA synthesis, covalent binding to mitochondrial DNA, DNA repair, and mitochondrial dysfunction in the context of developing individuals and cellular differentiation. Microbiologists, toxicologists, biochemists, and molecular pharmacologists will find the book invaluable.

Author : Peter A. Whittaker
Publisher : Longman Publishing Group
ISBN 13 : 9780582443822
Total Pages : 160 pages
Book Rating : 4.22/5 ( download)

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Download or read book Mitochondria written by Peter A. Whittaker and published by Longman Publishing Group. This book was released on 1978 with total page 160 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Author :
Publisher : Academic Press
ISBN 13 : 9780443191237
Total Pages : 0 pages
Book Rating : 4.39/5 ( download)

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Download or read book Mitochondria and Bacterial Pathogens - Part B written by and published by Academic Press. This book was released on 2023-05-31 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mitochondria and Bacterial Pathogens, Part B, Volume 375 discusses different pathogenic mechanisms that converge on the ability of bacteria to control the mitochondrial compartment of host cells. Chapters in this new release include Interaction between host cell mitochondria and Coxiella Burnetii, Control of mitochondrial functions by Pseudomonas aeruginosa in cystic fibrosis, Mitochondrial and bacterial ATP synthase: Structural similarities and divergences to exploit in the battle against M. tuberculosis, Role of mitochondria in the enteropathogenic Escherichia coli disease, Mitochondria dynamics and antibiotic resistance, and more.

Author : Sabzali Javadov
Publisher :
ISBN 13 : 9783039363841
Total Pages : 434 pages
Book Rating : 4.40/5 ( download)

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Download or read book Mitochondria in Health and Diseases written by Sabzali Javadov and published by . This book was released on 2020-09-04 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mitochondria are subcellular organelles evolved by the endosymbiosis of bacteria with eukaryotic cells. They are the main source of ATP in the cell and engaged in other aspects of cell metabolism and cell function, including the regulation of ion homeostasis, cell growth, redox status, and cell signaling. Due to their central role in cell life and death, mitochondria are also involved in the pathogenesis and progression of human diseases/conditions, including neurodegenerative and cardiovascular disorders, cancer, diabetes, inflammation, and aging. However, despite the increasing number of studies, precise mechanisms whereby mitochondria are involved in the regulation of basic physiological functions, as well as their role in the cell under pathophysiological conditions, remain unknown. A lack of in-depth knowledge of the regulatory mechanisms of mitochondrial metabolism and function, as well as interplay between the factors that transform the organelle from its role in pro-survival to pro-death, have hindered the development of new mitochondria-targeted pharmacological and conditional approaches for the treatment of human diseases. This book highlights the latest achievements in elucidating the role of mitochondria under physiological conditions, in various cell/animal models of human diseases, and in patients.