Microfluidics In Cell Biology Part C Microfluidics For Cellular And Subcellular Analysis

Author :
Publisher : Academic Press
ISBN 13 : 0128142855
Total Pages : 266 pages
Book Rating : 4.51/5 ( download)

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Download or read book Microfluidics in Cell Biology Part C: Microfluidics for Cellular and Subcellular Analysis written by and published by Academic Press. This book was released on 2018-11-22 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microfluidics in Cell Biology Part C, Volume 148, a new release in the Methods in Cell Biology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Unique to this updated volume are three sections on microfluidics in various multi-cellular models, including microfluidics in cell monolayers/spheroids, microfluidics in organ on chips, and microfluidics in model organisms. Specific chapters discuss collective migration in microtubes, leukocyte adhesion dynamics on endothelial monolayers under flow, constrained spheroid for perfusion culture, cells in droplet arrays, heart on chips, kidney on chips, liver on chips, and more. Contains contributions from experts in the field from across the world Covers a wide array of topics on both mitosis and meiosis Includes relevant, analysis based topics

Author :
Publisher : Academic Press
ISBN 13 : 9780128142806
Total Pages : 0 pages
Book Rating : 4.04/5 ( download)

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Download or read book Microfluidics in Cell Biology: Part A: Microfluidics for Multicellular Systems written by and published by Academic Press. This book was released on 2018-07-25 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microfluidics in Cell Biology Part A: Volume 146, the latest release in the Methods in Cell Biology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Unique to this updated volume are sections on Cell monolayers/spheroids, Collective migration in microtubes, Leukocyte adhesion dynamics on endothelial monolayers under flow, Constrained spheroid for perfusion culture, Cells in droplet arrays, Heart on chips, Kidney on chips, Liver on chips and hepatic immune responses, Gut on chips, 3D microvascular model-based lymphoma model, Blood brain barrier on chips, Multi-organ-on-a-chip for pharmacokinetic analysis, Cancer immunotherapy on chips, and more.

Author : Chang Lu
Publisher : Springer
ISBN 13 : 3319300199
Total Pages : 382 pages
Book Rating : 4.91/5 ( download)

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Download or read book Microfluidic Methods for Molecular Biology written by Chang Lu and published by Springer. This book was released on 2016-05-14 with total page 382 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers the state-of-the-art research on molecular biology assays and molecular techniques enabled or enhanced by microfluidic platforms. Topics covered include microfluidic methods for cellular separations and single cell studies, droplet-based approaches to study protein expression and forensics, and microfluidic in situ hybridization for RNA analysis. Key molecular biology studies using model organisms are reviewed in detail. This is an ideal book for students and researchers in the microfluidics and molecular biology fields as well as engineers working in the biotechnology industry. This book also: Reviews exhaustively the latest techniques for single-cell genetic, epigenetic, metabolomic, and proteomic analysis Illustrates microfluidic approaches for inverse metabolic engineering, as well as analysis of circulating exosomes Broadens readers’ understanding of microfluidics convection-based PCR technology, microfluidic RNA-seq, and microfluidics for robust mobile diagnostics

Author : Jin-Ming Lin
Publisher : Springer
ISBN 13 : 9789813297319
Total Pages : 261 pages
Book Rating : 4.1X/5 ( download)

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Download or read book Microfluidics for Single-Cell Analysis written by Jin-Ming Lin and published by Springer. This book was released on 2020-09-06 with total page 261 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book summarizes the various microfluidic-based approaches for single-cell capture, isolation, manipulation, culture and observation, lysis, and analysis. Single-cell analysis reveals the heterogeneities in morphology, functions, composition, and genetic performance of seemingly identical cells, and advances in single-cell analysis can overcome the difficulties arising due to cell heterogeneity in the diagnostics for a targeted model of disease. This book provides a detailed review of the state-of-the-art techniques presenting the pros and cons of each of these methods. It also offers lessons learned and tips from front-line investigators to help researchers overcome bottlenecks in their own studies. Highlighting a number of techniques, such as microfluidic droplet techniques, combined microfluidics-mass-spectrometry systems, and nanochannel sampling, it describes in detail a new microfluidic chip-based live single-cell extractor (LSCE) developed in the editor’s laboratory, which opens up new avenues to use open microfluidics in single-cell extraction, single-cell mass spectrometric analysis, single-cell adhesion analysis and subcellular operations. Serving as both an elementary introduction and advanced guidebook, this book interests and inspires scholars and students who are currently studying or wish to study microfluidics-based cell analysis methods.

Author : Wei-Cheng Tian
Publisher : Springer Science & Business Media
ISBN 13 : 0387094806
Total Pages : 429 pages
Book Rating : 4.09/5 ( download)

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Download or read book Microfluidics for Biological Applications written by Wei-Cheng Tian and published by Springer Science & Business Media. This book was released on 2009-03-02 with total page 429 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microfluidics for Biological Applications provides researchers and scientists in the biotechnology, pharmaceutical, and life science industries with an introduction to the basics of microfluidics and also discusses how to link these technologies to various biological applications at the industrial and academic level. Readers will gain insight into a wide variety of biological applications for microfluidics. The material presented here is divided into four parts, Part I gives perspective on the history and development of microfluidic technologies, Part II presents overviews on how microfluidic systems have been used to study and manipulate specific classes of components, Part III focuses on specific biological applications of microfluidics: biodefense, diagnostics, high throughput screening, and tissue engineering and finally Part IV concludes with a discussion of emerging trends in the microfluidics field and the current challenges to the growth and continuing success of the field.

Author : Christopher Bettinger
Publisher : William Andrew
ISBN 13 : 143773460X
Total Pages : 454 pages
Book Rating : 4.07/5 ( download)

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Download or read book Microfluidic Cell Culture Systems written by Christopher Bettinger and published by William Andrew. This book was released on 2012-12-31 with total page 454 pages. Available in PDF, EPUB and Kindle. Book excerpt: The fields of microfluidics and BioMEMS are significantly impacting cell biology research and applications through the application of engineering solutions to human disease and health problems. The dimensions of microfluidic channels are well suited to the physical scale of biological cells, and the many advantages of microfluidics make it an attractive platform for new techniques in biology. This new professional reference applies the techniques of microsystems to cell culture applications. The authors provide a thoroughly practical guide to the principles of microfluidic device design and operation and their application to cell culture techniques. The resulting book is crammed with strategies and techniques that can be immediately deployed in the lab. Equally, the insights into cell culture applications will provide those involved in traditional microfluidics and BioMEMS with an understanding of the specific demands and opportunities presented by biological applications. The goal is to guide new and interested researchers and technology developers to the important areas and state-of-the-practice strategies that will enhance the efficiency and value of their technologies, devices and biomedical products. Provides insights into the design and development of microfluidic systems with a specific focus on cell culture applications Focuses on strategies and techniques for the design and fabrication of microfluidic systems and devices for cell culture Provides balanced coverage of microsystems engineering and bioengineering

Author : James Kyle Campbell
Publisher :
ISBN 13 :
Total Pages : 150 pages
Book Rating : 4.45/5 ( download)

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Download or read book Microfluidics for Optics and Quantitative Cell Biology written by James Kyle Campbell and published by . This book was released on 2008 with total page 150 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microfluidics is a quickly expanding field with numerous applications. The advent of rapid-prototyping and soft-lithography allow for easy and inexpensive fabrication of microfluidic devices. Fluid manipulation on the microscale allows for new functionalities of devices and components not available on the macroscale. Fluid flows on the microscale are laminar with chemical mixing defined strictly by diffusion allowing us to design microfluidic devices with precise control of fluid flow and chemical concentration. New microfluidic technologies can provide new functionalities for micro-total analysis systems for greater device integration and portability. To expand the utilization of microfluidics, this dissertation discusses new microfluidic techniques and devices. Chapter 2 examines microfluidics for quantitative cell biology. New techniques discussed in this dissertation allow us to use microfluidics to study cellular response on a cell-by-cell basis in stable environments. Part of this chapter includes new architectures for creating chemical concentration gradients in microfluidic devices and their applications cell biology. The rest of Chapter 2 introduces a device which allows for cells to grow to high densities in chemostatic conditions. Chapter 3 introduces the merger of optics and microfluidics named "optofluidics". This subset of microfluidics uses the techniques and materials of microfluidics for optical applications. This dissertation describes optofluidic projects involving light manipulation such as a switch, actuator and lens.

Author :
Publisher :
ISBN 13 : 9789813297302
Total Pages : 263 pages
Book Rating : 4.01/5 ( download)

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Download or read book Microfluidics for Single-cell Analysis written by and published by . This book was released on 2019 with total page 263 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book summarizes the various microfluidic-based approaches for single-cell capture, isolation, manipulation, culture and observation, lysis, and analysis. Single-cell analysis reveals the heterogeneities in morphology, functions, composition, and genetic performance of seemingly identical cells, and advances in single-cell analysis can overcome the difficulties arising due to cell heterogeneity in the diagnostics for a targeted model of disease. This book provides a detailed review of the state-of-the-art techniques presenting the pros and cons of each of these methods. It also offers lessons learned and tips from front-line investigators to help researchers overcome bottlenecks in their own studies. Highlighting a number of techniques, such as microfluidic droplet techniques, combined microfluidics-mass-spectrometry systems, and nanochannel sampling, it describes in detail a new microfluidic chip-based live single-cell extractor (LSCE) developed in the editor's laboratory, which opens up new avenues to use open microfluidics in single-cell extraction, single-cell mass spectrometric analysis, single-cell adhesion analysis and subcellular operations. Serving as both an elementary introduction and advanced guidebook, this book interests and inspires scholars and students who are currently studying or wish to study microfluidics-based cell analysis methods.

Author : Xiao-Ying Yu
Publisher : BoD – Books on Demand
ISBN 13 : 9535127853
Total Pages : 424 pages
Book Rating : 4.57/5 ( download)

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Download or read book Advances in Microfluidics written by Xiao-Ying Yu and published by BoD – Books on Demand. This book was released on 2016-11-23 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt: Increasing innovations and applications make microfluidics a versatile choice for researchers in many disciplines. This book consists of multiple review chapters that aim to cover recent advances and new applications of microfluidics in biology, electronics, energy, and materials sciences. It provides comprehensive views of various aspects of microfluidics ranging from fundamentals of fabrication, flow control, and droplet manipulation to the most recent exploration in emerging areas such as material synthesis, imaging and novel spectroscopy, and marriage with electronics. The chapters have many illustrations showcasing exciting results. This book should be useful for those who are eager to learn more about microfluidics as well as researchers who want to pick up new concepts and developments in this fast-growing field.

Author : Robert Langer
Publisher : World Scientific
ISBN 13 : 9814405531
Total Pages : 495 pages
Book Rating : 4.39/5 ( download)

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Download or read book Microfluidic Technologies For Human Health written by Robert Langer and published by World Scientific. This book was released on 2012-12-26 with total page 495 pages. Available in PDF, EPUB and Kindle. Book excerpt: The field of microfluidics has in the last decade permeated many disciplines, from physics to biology and chemistry, and from bioengineering to medical research. One of the most important applications of lab-on-a-chip devices in medicine and related disciplines is disease diagnostics, which involves steps from biological sample/analyte loading to storage, detection, and analysis. The chapters collected in this book detail recent advances in these processes using microfluidic devices and systems. The reviews of portable devices for diagnostic purposes are likely to evoke interest and raise new research questions in interdisciplinary fields (e.g., efficient MEMS/microfluidic engineering driven by biological and medical applications).The variety of the selected topics (general relevance of microfluidics in medical and bioengineering research, fabrication, advances in on-chip sample detection and analysis, and specific disease models) ensures that each of them can be viewed in the larger context of microfluidic-mediated diagnostics.