Metabolomics By In Vivo Nmr

Author : Robert G. Shulman
Publisher : John Wiley & Sons
ISBN 13 : 0470011491
Total Pages : 206 pages
Book Rating : 4.92/5 ( download)

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Download or read book Metabolomics by In Vivo NMR written by Robert G. Shulman and published by John Wiley & Sons. This book was released on 2005-06-10 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metabolism By In Vivo NMR reviews and extends the experimental and theoretical reports concerning in vivo NMR, a pioneering approach that offers versatile new ways of studying metabolic pathways. Perfectly timed to coincide with recent findings that demonstrate the novelty and strength of this approach, the book covers recent applications in biochemistry, medicine, and psychology; in vivo NMR techniques; MCA; glucose metabolism focusing on glycogen; the value of muscle glycogen measurements in exercise; and much more. This book is unique in linking in vivo 13C NMR measurements of neuronal activity and energetics with applications to functional imaging and certain disease states Provides a fundamental neurochemical explanation of brain activity applicable to functional imaging, theories of neuronal activity and disease states, e.g. epilepsy, psychiatric diseases and developmental disorders Novel and potentially controversial Will inspire future research directions.

Author : Norbert W. Lutz
Publisher : Cambridge University Press
ISBN 13 : 0521765900
Total Pages : 641 pages
Book Rating : 4.09/5 ( download)

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Download or read book Methodologies for Metabolomics written by Norbert W. Lutz and published by Cambridge University Press. This book was released on 2013-01-21 with total page 641 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metabolomics, the global characterisation of the small molecule complement involved in metabolism, has evolved into a powerful suite of approaches for understanding the global physiological and pathological processes occurring in biological organisms. The diversity of metabolites, the wide range of metabolic pathways and their divergent biological contexts require a range of methodological strategies and techniques. Methodologies for Metabolomics provides a comprehensive description of the newest methodological approaches in metabolomic research. The most important technologies used to identify and quantify metabolites, including nuclear magnetic resonance and mass spectrometry, are highlighted. The integration of these techniques with classical biological methods is also addressed. Furthermore, the book presents statistical and chemometric methods for evaluation of the resultant data. The broad spectrum of topics includes a vast variety of organisms, samples and diseases, ranging from in vivo metabolomics in humans and animals to in vitro analysis of tissue samples, cultured cells and biofluids.

Author : Hector C Keun
Publisher : Royal Society of Chemistry
ISBN 13 : 184973643X
Total Pages : 384 pages
Book Rating : 4.35/5 ( download)

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Download or read book NMR-based Metabolomics written by Hector C Keun and published by Royal Society of Chemistry. This book was released on 2018-01-17 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the state of the art in the application of NMR spectroscopy to metabolomics and will be a key title for researchers and practitioners.

Author : G. A. Nagana Gowda
Publisher : Humana
ISBN 13 : 9781493996926
Total Pages : 489 pages
Book Rating : 4.24/5 ( download)

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Download or read book NMR-Based Metabolomics written by G. A. Nagana Gowda and published by Humana. This book was released on 2020-08-29 with total page 489 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides broad coverage of nuclear magnetic resonance (NMR) spectroscopy-based methods and applications for the analysis of metabolites in a wide range of biological samples, from biofluids, cells, animal models, human, to plants and foods. The applications range from mechanistic understanding, biomarker discovery, environmental studies, and drug discovery to nutrition, while NMR methods include global, targeted, and isotope tracer-based techniques. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, NMR-Based Metabolomics: Methods and Protocols serves as a wealth of information for beginners as well as advanced practitioners and also as stepping stones for further advances in the field of metabolomics.

Author : Mohammad Raza Akhter
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.07/5 ( download)

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Download or read book In Vivo NMR-based Metabolomics of Daphnia Magna written by Mohammad Raza Akhter and published by . This book was released on 2015 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Author : Firas H. Kobeissy
Publisher : CRC Press
ISBN 13 : 1466565993
Total Pages : 718 pages
Book Rating : 4.99/5 ( download)

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Download or read book Brain Neurotrauma written by Firas H. Kobeissy and published by CRC Press. This book was released on 2015-02-25 with total page 718 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the contribution from more than one hundred CNS neurotrauma experts, this book provides a comprehensive and up-to-date account on the latest developments in the area of neurotrauma including biomarker studies, experimental models, diagnostic methods, and neurotherapeutic intervention strategies in brain injury research. It discusses neurotrauma mechanisms, biomarker discovery, and neurocognitive and neurobehavioral deficits. Also included are medical interventions and recent neurotherapeutics used in the area of brain injury that have been translated to the area of rehabilitation research. In addition, a section is devoted to models of milder CNS injury, including sports injuries.

Author : Miroslava Čuperlović-Culf
Publisher : Elsevier
ISBN 13 : 1908818263
Total Pages : 446 pages
Book Rating : 4.63/5 ( download)

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Download or read book NMR Metabolomics in Cancer Research written by Miroslava Čuperlović-Culf and published by Elsevier. This book was released on 2012-12-17 with total page 446 pages. Available in PDF, EPUB and Kindle. Book excerpt: The application of nuclear magnetic resonance (NMR) metabolomics in cancer research requires an understanding of the many possibilities that NMR metabolomics can offer, as well as of the specific characteristics of the cancer metabolic phenotype and the open questions in cancer research. NMR metabolomics in cancer research presents a detailed account of the NMR spectroscopy methods applied to metabolomics mixture analysis along with a discussion of their advantages and disadvantages. Following an overview of the potential use of NMR metabolomics in cancer research, the book begins with an examination of the cancer metabolic phenotype and experimental methodology, before moving on to cover data pre-processing and data analysis. Chapters in the latter part of the book look at dynamic metabolic profiling, biomarker discovery, and the application of NMR metabolomics for different types of cancer, before a concluding chapter discusses future perspectives in the field. Focused description of NMR spectroscopy needed by cancer biologists who are starting to use metabolomics Current overview of knowledge related to the cancer metabolic phenotype from the perspective of metabolomics applications Information about the best practices in NMR metabolomics experimentation and data preprocessing as applied to different sample types

Author : Angelo D'Alessandro
Publisher : Humana
ISBN 13 : 9781493992386
Total Pages : 459 pages
Book Rating : 4.84/5 ( download)

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Download or read book High-Throughput Metabolomics written by Angelo D'Alessandro and published by Humana. This book was released on 2020-06-06 with total page 459 pages. Available in PDF, EPUB and Kindle. Book excerpt: This detailed volume focuses on recent technological, computational, and biostatistical advances in the field of high-throughput metabolomics. Chapters encompass methods, platforms, and analytical strategies for steady state measurements and metabolic flux analysis with stable isotope-labeled tracers, in biological matrices of clinical relevance and model organisms. Mass spectrometry-based or orthogonal methods are discussed, along with computational and statistical methods to address data sparsity in high-throughput metabolomics approaches. As a part of the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, High-Throughput Metabolomics: Methods and Protocols provides tools that can bring about the next generation of clinical biochemistry in a cost-effective, rigorous fashion, exponentially advancing our capacity to investigate nature while hastening the advent of personalized medicine.

Author : John C. Lindon
Publisher : Elsevier
ISBN 13 : 0080468004
Total Pages : 573 pages
Book Rating : 4.06/5 ( download)

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Download or read book The Handbook of Metabonomics and Metabolomics written by John C. Lindon and published by Elsevier. This book was released on 2011-08-11 with total page 573 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular biology operates at three levels – genes, proteins and metabolites. This book is unique in that it provides a comprehensive description of an approach (metabonomics) to characterise the endogenous metabolites in a living system, complementing gene and protein studies (genomics and proteomics). These "omics" methods form the basis for understanding biology at a systems level. The Handbook of Metabonomics and Metabolomics aims to be the definitive work on the rapidly expanding subjects of metabolic profiling, metabolite and biomarker identification, encompassing the fields of metabonomics and metabolomics. It covers the principles of the subject, the analytical and statistical techniques used and the wide variety of applications. * comprehensive description of an approach (metabonomics) to characterise the endogenous metabolites in a living system, complementing gene and protein studies* aims to be the definitive work on the rapidly expanding subjects of metabolic profiling, metabolite and biomarker identification* covers the principles of the subject, the analytical and statistical techniques used and the wide variety of applications.

Author : G. A. Nagana Gowda
Publisher :
ISBN 13 : 9781493996902
Total Pages : 489 pages
Book Rating : 4.08/5 ( download)

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Download or read book NMR-Based Metabolomics written by G. A. Nagana Gowda and published by . This book was released on 2019 with total page 489 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides broad coverage of nuclear magnetic resonance (NMR) spectroscopy-based methods and applications for the analysis of metabolites in a wide range of biological samples, from biofluids, cells, animal models, human, to plants and foods. The applications range from mechanistic understanding, biomarker discovery, environmental studies, and drug discovery to nutrition, while NMR methods include global, targeted, and isotope tracer-based techniques. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, NMR-Based Metabolomics: Methods and Protocols serves as a wealth of information for beginners as well as advanced practitioners and also as stepping stones for further advances in the field of metabolomics.