Metabolic Phenotyping In Personalized And Public Healthcare

Author : Jeremy Nicholson
Publisher : Academic Press
ISBN 13 : 0128004142
Total Pages : 430 pages
Book Rating : 4.42/5 ( download)

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Download or read book Metabolic Phenotyping in Personalized and Public Healthcare written by Jeremy Nicholson and published by Academic Press. This book was released on 2016-02-11 with total page 430 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metabolic Phenotyping in Personalized and Public Healthcare provides information on the widespread recognition that a personalized or stratified approach to patient treatment may offer a more efficient and effective healthcare solution than phenotype-led approaches.In order to achieve that objective, a deep personal description is required at the level of the genome, proteome, metabolome, or preferably a combination of these aided by technology. This book, edited and written by the outstanding luminaries of this evolving field, evaluates metabolic profiling and its uses across personalized and population healthcare, while also covering the advent of new technology fields, such as surgical metabonomics. In addition, the text presents specific examples of where this technology has been used clinically and with efficacy, pointing towards a framework and protocol for usage as it hits the clinical mainstream. Translates the conjunction of new surgical tools for intraoperative, real-time, metabolite evaluation and direct analysis of biofluid samples into novel options for augmented clinical decision-making Discusses longitudinal sampling from individual patients for stratified medicine Covers high resolution analytical spectroscopy and sophisticated computational modelling for prediction of adverse reactions in critical care scenarios, prognostic evaluation of cancer from biofluidism, and prognostic prediction of metabolism or response of patients to pharmaceutical interventions Encapsulates recent technology options for broader population profiling considerations, in particular, the metabolome-wide association studies (MWAS) that aid the translational researcher in identifying metabolic patterns associated with disease Foreword written by Professor Dame Sally Davies who is the Chief Medical Officer for England

Author : John C. Lindon
Publisher : Elsevier
ISBN 13 : 9780128122938
Total Pages : 0 pages
Book Rating : 4.35/5 ( download)

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Download or read book The Handbook of Metabolic Phenotyping written by John C. Lindon and published by Elsevier. This book was released on 2018-10-05 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Handbook of Metabolic Phenotyping is the definitive work on the rapidly developing subject of metabolic phenotyping. It explores in detail the wide array of analytical chemistry and statistical modeling techniques used in the field, coupled with surveys of the various application areas in human development, nutrition, disease, therapy, and epidemiology to create a comprehensive exploration of the area of study. It covers recent studies that integrate the various -omics data sets to derive a systems biology view. It also addresses current issues on standardization, assay and statistics validation, and data storage and sharing. Written by experts with many years of practice in the field who pioneered many of the approaches widely used today, The Handbook of Metabolic Phenotyping is a valuable resource for postgrads and research scientists studying and furthering the field of metabolomics.

Author : John C. Lindon
Publisher : Elsevier
ISBN 13 : 0128122943
Total Pages : 619 pages
Book Rating : 4.45/5 ( download)

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Download or read book The Handbook of Metabolic Phenotyping written by John C. Lindon and published by Elsevier. This book was released on 2018-10-04 with total page 619 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Handbook of Metabolic Phenotyping is the definitive work on the rapidly developing subject of metabolic phenotyping. It explores in detail the wide array of analytical chemistry and statistical modeling techniques used in the field, coupled with surveys of the various application areas in human development, nutrition, disease, therapy, and epidemiology to create a comprehensive exploration of the area of study. It covers recent studies that integrate the various -omics data sets to derive a systems biology view. It also addresses current issues on standardization, assay and statistics validation, and data storage and sharing. Written by experts with many years of practice in the field who pioneered many of the approaches widely used today, The Handbook of Metabolic Phenotyping is a valuable resource for postgrads and research scientists studying and furthering the field of metabolomics. Contains theoretical and practical explanations of all the main analytical chemistry techniques used in metabolic phenotyping Explores, in detail, the many diverse statistical approaches used in the field Offers practical tips for successfully conducting metabolic phenotyping studies Features reviews of all of the various fields of activity relating to human studies

Author : James E. Barrett
Publisher : Springer Nature
ISBN 13 : 3030353621
Total Pages : 466 pages
Book Rating : 4.29/5 ( download)

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Download or read book Concepts and Principles of Pharmacology written by James E. Barrett and published by Springer Nature. This book was released on 2019-12-24 with total page 466 pages. Available in PDF, EPUB and Kindle. Book excerpt: Celebrating 100 years of HEP, this volume will discuss key pharmacological discoveries and concepts of the past 100 years. These discoveries have dramatically changed the medical treatment paradigms of many diseases and these concepts have and will continue to shape discovery of new medicinies. Newly evolving technologies will similarly be discussed as they will shape the future of the pharmacology and, accordingly, medical therapy.

Author : Bruce F. Cullen
Publisher : Lippincott Williams & Wilkins
ISBN 13 : 1975199081
Total Pages : 4682 pages
Book Rating : 4.81/5 ( download)

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Download or read book Barash, Cullen, and Stoelting's Clinical Anesthesia written by Bruce F. Cullen and published by Lippincott Williams & Wilkins. This book was released on 2023-08-24 with total page 4682 pages. Available in PDF, EPUB and Kindle. Book excerpt: Covering the full spectrum of clinical issues and options in anesthesiology, Barash, Cullen, and Stoelting’s Clinical Anesthesia, Ninth Edition, edited by Drs. Bruce F. Cullen, M. Christine Stock, Rafael Ortega, Sam R. Sharar, Natalie F. Holt, Christopher W. Connor, and Naveen Nathan, provides insightful coverage of pharmacology, physiology, co-existing diseases, and surgical procedures. This award-winning text delivers state-of-the-art content unparalleled in clarity and depth of coverage that equip you to effectively apply today’s standards of care and make optimal clinical decisions on behalf of your patients.

Author : Salvatore Fanali
Publisher : Elsevier
ISBN 13 : 0128093447
Total Pages : 838 pages
Book Rating : 4.43/5 ( download)

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Download or read book Liquid Chromatography written by Salvatore Fanali and published by Elsevier. This book was released on 2017-06-23 with total page 838 pages. Available in PDF, EPUB and Kindle. Book excerpt: Liquid Chromatography: Applications, Second Edition,is a single source of authoritative information on all aspects of the practice of modern liquid chromatography. It gives those working in both academia and industry the opportunity to learn, refresh, and deepen their knowledge of the wide variety of applications in the field. In the years since the first edition was published, thousands of papers have been released on new achievements in liquid chromatography, including the development of new stationary phases, improvement of instrumentation, development of theory, and new applications in biomedicine, metabolomics, proteomics, foodomics, pharmaceuticals, and more. This second edition addresses these new developments with updated chapters from the most expert researchers in the field. Emphasizes the integration of chromatographic methods and sample preparation Explains how liquid chromatography is used in different industrial sectors Covers the most interesting and valuable applications in different fields, e.g., proteomic, metabolomics, foodomics, pollutants and contaminants, and drug analysis (forensic, toxicological, pharmaceutical, biomedical) Includes references and tables with commonly used data to facilitate research, practical work, comparison of results, and decision-making

Author : Jose Agundez
Publisher : Frontiers Media SA
ISBN 13 : 2889638286
Total Pages : 281 pages
Book Rating : 4.84/5 ( download)

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Download or read book 10 Years of Pharmacogenetics and Pharmacogenomics written by Jose Agundez and published by Frontiers Media SA. This book was released on 2020-07-08 with total page 281 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Specialty Section “Pharmacogenetics and Pharmacogenomics” makes part of two different Journals: Frontiers in Pharmacology and Frontiers in Genetics. This Specialty Section focuses on the mechanisms by which genetic variations influence drug effects and adverse drug events, and cover basic research, clinical translation, applications in drug development and regulatory issues related to this field. Also, studies addressing the role of other factors such as epigenetics, phenotypic factors or drug-drug interactions on drug pharmacokinetics or pharmacodynamics are welcome. The editorial board is composed of 34 Associate Editors which, together with the Guest Associate Editors and the Reviewer Editors, constitute a team of nearly 340 leading experts in the field of Pharmacogenetics and Pharmacogenomics. This guarantees high quality in the reviewing process as well as short review times. A look back: 10 years of Frontiers in Pharmacogenetics & Pharmacogenomics (Continued in eBook)

Author : Alma Angélica Del Villar-Martínez
Publisher : CRC Press
ISBN 13 : 1000923517
Total Pages : 279 pages
Book Rating : 4.13/5 ( download)

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Download or read book Advances in Plant Biotechnology written by Alma Angélica Del Villar-Martínez and published by CRC Press. This book was released on 2023-08-31 with total page 279 pages. Available in PDF, EPUB and Kindle. Book excerpt: The goal of Advances in Plant Biotechnology is to integrate the most recent knowledge on tissue culture, secondary metabolites production under controlled conditions, scaling up to produce them at bioreactor level, and their industrial applications. The biosynthetic pathways and the factors that affect them and the accumulation of metabolites, including metabolomics in medicinal plants, are key components as well. Several extraction and encapsulation technological procedures are reviewed. The structure and function of metabolites from selected commercial crops are reported in detail. Finally, items of paramount importance, such as bioavailability and stability of metabolites in pharma and food products are deeply analyzed. Key Features: Strategies for obtaining selected metabolites through in vitro culture Application of biotechnological and bioengineering principles to the management of plant metabolites Description of the encapsulation of selected metabolites Bioavailability and stability of metabolites in pharma, food, and industrial sectors This book is mainly addressed to research scientists, technical staff, and private and public organizations involved in plant biotechnology and in its processing industries. Last, but not least, students at all levels and postdoctoral researchers have received special attention from all editors and authors in this publication.

Author : Joel Faintuch
Publisher : Academic Press
ISBN 13 : 0128191791
Total Pages : 640 pages
Book Rating : 4.98/5 ( download)

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Download or read book Precision Medicine for Investigators, Practitioners and Providers written by Joel Faintuch and published by Academic Press. This book was released on 2019-11-16 with total page 640 pages. Available in PDF, EPUB and Kindle. Book excerpt: Precision Medicine for Investigators, Practitioners and Providers addresses the needs of investigators by covering the topic as an umbrella concept, from new drug trials to wearable diagnostic devices, and from pediatrics to psychiatry in a manner that is up-to-date and authoritative. Sections include broad coverage of concerning disease groups and ancillary information about techniques, resources and consequences. Moreover, each chapter follows a structured blueprint, so that multiple, essential items are not overlooked. Instead of simply concentrating on a limited number of extensive and pedantic coverages, scholarly diagrams are also included. Provides a three-pronged approach to precision medicine that is focused on investigators, practitioners and healthcare providers Covers disease groups and ancillary information about techniques, resources and consequences Follows a structured blueprint, ensuring essential chapters items are not overlooked

Author : Ying Tan
Publisher : Springer
ISBN 13 : 9813295635
Total Pages : 340 pages
Book Rating : 4.36/5 ( download)

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Download or read book Data Mining and Big Data written by Ying Tan and published by Springer. This book was released on 2019-07-25 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes the refereed proceedings of the 4th International Conference on Data Mining and Big Data, DMBD 2019, held in Chiang Mai, Thailand, in July 2019. The 26 full papers and 8 short papers presented in this volume were carefully reviewed and selected from 79 submissions. They are organized in topical sections named: data analysis; prediction; clustering; classification; mining pattern; mining tasks.