Mathematical Modeling Of Biosensors

Author : Romas Baronas
Publisher : Springer Science & Business Media
ISBN 13 : 9048132436
Total Pages : 342 pages
Book Rating : 4.30/5 ( download)

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Download or read book Mathematical Modeling of Biosensors written by Romas Baronas and published by Springer Science & Business Media. This book was released on 2009-11-12 with total page 342 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biosensors are analytical devices in which speci?c recognition of the chemical substances is performed by biological material. The biological material that serves as recognition element is used in combination with a transducer. The transducer transforms concentration of substrate or product to electrical signal that is amp- ?ed and further processed. The biosensors may utilize enzymes, antibodies, nucleic acids, organelles, plant and animal tissue, whole organism or organs. Biosensors containing biological catalysts (enzymes) are called catalytical biosensors. These type of biosensors are the most abundant, and they found the largest application in medicine, ecology, and environmental monitoring. The action of catalytical biosensors is associated with substrate diffusion into biocatalytical membrane and it conversion to a product. The modeling of bios- sors involves solving the diffusion equations for substrate and product with a term containing a rate of biocatalytical transformation of substrate. The complications of modeling arise due to solving of partially differential equations with non-linear biocatalytical term and with complex boundary and initial conditions. The book starts with the modeling biosensors by analytical solution of partial differential equations. Historically this method was used to describe fundamental features of biosensors action though it is limited by substrate concentration, and is applicable for simple biocatalytical processes. Using this method the action of biosensors was analyzed at critical concentrations of substrate and enzyme activity.

Author : Romas Baronas
Publisher : Springer Nature
ISBN 13 : 3030655059
Total Pages : 456 pages
Book Rating : 4.51/5 ( download)

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Download or read book Mathematical Modeling of Biosensors written by Romas Baronas and published by Springer Nature. This book was released on 2021-02-15 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: This newly designed and enlarged edition offers an up-to-date presentation of biosensor development and modeling from both a chemical and a mathematical point of view. An entire new chapter in particular is dedicated to optimal design of biosensors. Two more new chapters discuss biosensors which utilize microbial cells and are based on carbon nanotubes respectively. All the other chapters have been revised and updated. The book contains unique modeling methods for amperometric, potentiometric and optical biosensors based mainly on biocatalysts . It examines processes that occur in the sensors' layers and at their interface, and it provides analytical and numerical methods to solve equations of conjugated enzymatic (chemical) and diffusion processes. The action of single enzyme as well as polyenzyme biosensors and biosensors based on chemically modified electrodes is studied. The modeling of biosensors that contain perforated membranes and multipart mass transport profiles is critically investigated. Furthermore, it is fully described how signals can be biochemically amplified, how cascades of enzymatic substrate conversion are triggered, and how signals are processed via a chemometric approach and artificial neuronal networks. The results of digital modeling are compared with both proximal analytical solutions and experimental data.

Author : Johann F. Osma
Publisher : OmniaScience
ISBN 13 : 8494187201
Total Pages : 221 pages
Book Rating : 4.09/5 ( download)

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Download or read book Biosensors: Recent advances and mathematical challenges written by Johann F. Osma and published by OmniaScience. This book was released on 2014-03-04 with total page 221 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many researchers and research groups around the globe are dealing with interdisciplinary problems and multidisciplinary groups; but especially those that deal everyday with biosensors have the feeling of not having enough personnel with the sufficient background to cover all topics. With this feeling in our minds, we decided to invite wonderful researchers from different parts to design this book, not as a conventional biosensor’s book, but as an interesting journey in the complex world of biosensors. A close look to some recent and key advances on the topic, but at the same time tips through novel mathematical modelling to improve our work, and last but not least, tricks to fool those undesired electrical disturbances that commonly messes our daily work can be found in these pages. Feel free to navigate the book through its chapters, once in your hands you will feel eager to learn more about biosensors. It has been an experience to put all this together; but now, with the book ready, we can say that this trip has being a wonderful adventure. That is why want to thank all the authors for their great contributions, the Editorial and Irene for their constant input, and to you, the reader, for being part of this book.

Author : William Hoiles
Publisher : Cambridge University Press
ISBN 13 : 1108423507
Total Pages : 475 pages
Book Rating : 4.02/5 ( download)

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Download or read book Dynamics of Engineered Artificial Membranes and Biosensors written by William Hoiles and published by Cambridge University Press. This book was released on 2018-05-03 with total page 475 pages. Available in PDF, EPUB and Kindle. Book excerpt: A state-of-the-art guide to building synthetic membranes for biological devices, covering their construction, measurement, and modelling.

Author : Avner Friedman
Publisher : Springer
ISBN 13 : 3319083147
Total Pages : 152 pages
Book Rating : 4.48/5 ( download)

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Download or read book Mathematical Modeling of Biological Processes written by Avner Friedman and published by Springer. This book was released on 2014-09-19 with total page 152 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book on mathematical modeling of biological processes includes a wide selection of biological topics that demonstrate the power of mathematics and computational codes in setting up biological processes with a rigorous and predictive framework. Topics include: enzyme dynamics, spread of disease, harvesting bacteria, competition among live species, neuronal oscillations, transport of neurofilaments in axon, cancer and cancer therapy, and granulomas. Complete with a description of the biological background and biological question that requires the use of mathematics, this book is developed for graduate students and advanced undergraduate students with only basic knowledge of ordinary differential equations and partial differential equations; background in biology is not required. Students will gain knowledge on how to program with MATLAB without previous programming experience and how to use codes in order to test biological hypothesis.

Author : J. C. Misra
Publisher : World Scientific
ISBN 13 : 9812774858
Total Pages : 525 pages
Book Rating : 4.59/5 ( download)

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Download or read book Biomathematics written by J. C. Misra and published by World Scientific. This book was released on 2006 with total page 525 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book on modelling and simulation in biomathematics will be invaluable to researchers who are interested in the emerging areas of the field. Graduate students in related areas as well as lecturers will also find it beneficial. Some of the chapters have been written by distinguished experts in the field. Sample Chapter(s). Chapter 1: Detecting Mosaic Structures in DNA Sequence Alignments (1,349 KB). Contents: Detecting Mosaic Structures in DNA Sequence Alignments (D Husmeier); Application of Statistical Methodology and Model Design to Socio-Behaviour of HIV Transmission (J Oluwoye); A Stochastic Model Incorporating HIV Treatments for a Heterosexual Population: Impact on Threshold Conditions (R J Gallop et al.); Modeling and Identification of the Dynamics of the MF-Influenced Free-Radical Transformations in Lipid-Modeling Substances and Lipids (J Bentsman et al.); Computer Simulation of Self-Reorganization in Biological Cells (D Greenspan); Modelling Biological Gel Contraction by Cells: Consequences of Cell Traction Forces Distribution and Initial Stress (S Ramtani); Peristaltic Transport of Physiological Fluids (J C Misra & S K Pandey); Mathematical Modelling of DNA Knots and Links (J C Misra & S Mukherjee); Using Monodomain Computer Models for the Simulation of Electric Fields During Excitation Spread in Cardiac Tissue (G Plank); Flow in Tubes with Complicated Geometries with Special Application to Blood Flow in Large Arteries (G Jayaraman); Mathematical Modeling in Reproductive Biomedicine (S Sharma & S K Guha); Image Theory and Applications in Bioelectromagnetics (P D Einziger et al.); Dynamics of Humanoid Robots: Geometrical and Topological Duality (V G Ivancevic); The Effects of Body Composition on Energy Expenditure and Weight Dynamics During Hypophagia: A Setpoint Analysis (F P Kozusko); Mathematical Models in Population Dynamics and Ecology (R Diluo); Modelling in Bone Biomechanics (J C Misra & S Samanta). Readership: Graduate students, academic and researchers in biomathematics, mathematical biology, mathematical modeling, biotechnology, biocomputing, biophysics, bioengineering and mechanics."

Author : Florinel-Gabriel Banica
Publisher : John Wiley & Sons
ISBN 13 : 1118354230
Total Pages : 795 pages
Book Rating : 4.30/5 ( download)

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Download or read book Chemical Sensors and Biosensors written by Florinel-Gabriel Banica and published by John Wiley & Sons. This book was released on 2012-08-15 with total page 795 pages. Available in PDF, EPUB and Kindle. Book excerpt: Key features include: Self-assessment questions and exercises Chapters start with essential principles, then go on to address more advanced topics More than 1300 references to direct the reader to key literature and further reading Highly illustrated with 450 figures, including chemical structures and reactions, functioning principles, constructive details and response characteristics Chemical sensors are self-contained analytical devices that provide real-time information on chemical composition. A chemical sensor integrates two distinct functions: recognition and transduction. Such devices are widely used for a variety of applications, including clinical analysis, environment monitoring and monitoring of industrial processes. This text provides an up-to-date survey of chemical sensor science and technology, with a good balance between classical aspects and contemporary trends. Topics covered include: Structure and properties of recognition materials and reagents, including synthetic, biological and biomimetic materials, microorganisms and whole-cells Physicochemical basis of various transduction methods (electrical, thermal, electrochemical, optical, mechanical and acoustic wave-based) Auxiliary materials used e.g. synthetic and natural polymers, inorganic materials, semiconductors, carbon and metallic materials properties and applications of advanced materials (particularly nanomaterials) in the production of chemical sensors and biosensors Advanced manufacturing methods Sensors obtained by combining particular transduction and recognition methods Mathematical modeling of chemical sensor processes Suitable as a textbook for graduate and final year undergraduate students, and also for researchers in chemistry, biology, physics, physiology, pharmacology and electronic engineering, this bookis valuable to anyone interested in the field of chemical sensors and biosensors.

Author : Dimitrios I. Fotiadis
Publisher : John Wiley & Sons
ISBN 13 : 1119517354
Total Pages : 404 pages
Book Rating : 4.51/5 ( download)

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Download or read book Multiscale Modelling in Biomedical Engineering written by Dimitrios I. Fotiadis and published by John Wiley & Sons. This book was released on 2023-05-05 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: Multiscale Modelling in Biomedical Engineering Discover how multiscale modeling can enhance patient treatment and outcomes In Multiscale Modelling in Biomedical Engineering, an accomplished team of biomedical professionals delivers a robust treatment of the foundation and background of a general computational methodology for multi-scale modeling. The authors demonstrate how this methodology can be applied to various fields of biomedicine, with a particular focus on orthopedics and cardiovascular medicine. The book begins with a description of the relationship between multiscale modeling and systems biology before moving on to proceed systematically upwards in hierarchical levels from the molecular to the cellular, tissue, and organ level. It then examines multiscale modeling applications in specific functional areas, like mechanotransduction, musculoskeletal, and cardiovascular systems. Multiscale Modelling in Biomedical Engineering offers readers experiments and exercises to illustrate and implement the concepts contained within. Readers will also benefit from the inclusion of: A thorough introduction to systems biology and multi-scale modeling, including a survey of various multi-scale methods and approaches and analyses of their application in systems biology Comprehensive explorations of biomedical imaging and nanoscale modeling at the molecular, cell, tissue, and organ levels Practical discussions of the mechanotransduction perspective, including recent progress and likely future challenges In-depth examinations of risk prediction in patients using big data analytics and data mining Perfect for undergraduate and graduate students of bioengineering, biomechanics, biomedical engineering, and medicine, Multiscale Modelling in Biomedical Engineering will also earn a place in the libraries of industry professional and researchers seeking a one-stop reference to the basic engineering principles of biological systems.

Author : Bastian E. Rapp
Publisher : Elsevier
ISBN 13 : 0128240237
Total Pages : 850 pages
Book Rating : 4.36/5 ( download)

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Download or read book Microfluidics written by Bastian E. Rapp and published by Elsevier. This book was released on 2022-10-07 with total page 850 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microfluidics: Modeling, Mechanics and Mathematics, Second Edition provides a practical, lab-based approach to nano- and microfluidics, including a wealth of practical techniques, protocols and experiments ready to be put into practice in both research and industrial settings. This practical approach is ideally suited to researchers and R&D staff in industry. Additionally, the interdisciplinary approach to the science of nano- and microfluidics enables readers from a range of different academic disciplines to broaden their understanding. Alongside traditional fluid/transport topics, the book contains a wealth of coverage of materials and manufacturing techniques, chemical modification/surface functionalization, biochemical analysis, and the biosensors involved. This fully updated new edition also includes new sections on viscous flows and centrifugal microfluidics, expanding the types of platforms covered to include centrifugal, capillary and electro kinetic platforms. Provides a practical guide to the successful design and implementation of nano- and microfluidic processes (e.g., biosensing) and equipment (e.g., biosensors, such as diabetes blood glucose sensors) Provides techniques, experiments and protocols that are ready to be put to use in the lab, or in an academic or industry setting Presents a collection of 3D-CAD and image files on a companion website

Author : Pier Andrea Serra
Publisher : BoD – Books on Demand
ISBN 13 : 9533074485
Total Pages : 462 pages
Book Rating : 4.81/5 ( download)

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Download or read book New Perspectives in Biosensors Technology and Applications written by Pier Andrea Serra and published by BoD – Books on Demand. This book was released on 2011-07-27 with total page 462 pages. Available in PDF, EPUB and Kindle. Book excerpt: A biosensor is a detecting device that combines a transducer with a biologically sensitive and selective component. Biosensors can measure compounds present in the environment, chemical processes, food and human body at low cost if compared with traditional analytical techniques. This book covers a wide range of aspects and issues related to biosensor technology, bringing together researchers from 12 different countries. The book consists of 20 chapters written by 69 authors and divided in three sections: Biosensors Technology and Materials, Biosensors for Health and Biosensors for Environment and Biosecurity.