Management Of Bone Disease And Kidney Failure In Multiple Myeloma

Author : Elena Zamagni
Publisher : Springer Nature
ISBN 13 : 3030636623
Total Pages : 213 pages
Book Rating : 4.23/5 ( download)

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Download or read book Management of Bone Disease and Kidney Failure in Multiple Myeloma written by Elena Zamagni and published by Springer Nature. This book was released on 2021-01-11 with total page 213 pages. Available in PDF, EPUB and Kindle. Book excerpt: This pocket guide provides a concise yet comprehensive overview of the two most prominent clinical features of multiple myeloma (MM), bone disease and renal failure. The first half of the text reviews critical aspects of bone disease in MM, including pathophysiology, the use of imaging modalities and drugs in treatment, and the role of orthopedic surgery. The latter half of the book reviews major components of kidney disease in MM, from pathophysiology to treatment. Written by experts in the field, Management of Bone Disease and Kidney Failure in Multiple Myeloma: A Pocket Guide is a valuable resource for clinicians and practitioners who manage patients afflicted with multiple myeloma.

Author : Ravi Vij
Publisher : JP Medical Ltd
ISBN 13 : 9350252651
Total Pages : 234 pages
Book Rating : 4.59/5 ( download)

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Download or read book Contemporary Management of Multiple Myeloma written by Ravi Vij and published by JP Medical Ltd. This book was released on 2011-11-08 with total page 234 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a practical guide to multiple myeloma. Beginning with the epidemiology, etiology and biology of the disease, the text then discusses clinical scenarios, diagnosis and various treatment options, including induction therapy, hematopoietic stem cell transplantation and treatment of relapsed/refractory cases. Authored by a US-based specialist, this book provides 166 detailed illustrations, tables, figures and algorithms to help understanding.

Author : James Berenson
Publisher : Springer Science & Business Media
ISBN 13 :
Total Pages : 386 pages
Book Rating : 4.97/5 ( download)

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Download or read book Biology and Management of Multiple Myeloma written by James Berenson and published by Springer Science & Business Media. This book was released on 2004-05-14 with total page 386 pages. Available in PDF, EPUB and Kindle. Book excerpt: Features a comprehensive review of advances in the biology and treatment of myeloma; examination of epidemiolgical findings and prognostic factors; thorough analysis of conventional treatment regimens; discussion of immunologic targeting, drug resistance inhibitors, and antitumor agents; and insights that can be directly applied to the laboratory and the clinic.

Author : G. David Roodman
Publisher : Springer Science & Business Media
ISBN 13 : 1607615541
Total Pages : 257 pages
Book Rating : 4.45/5 ( download)

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Download or read book Myeloma Bone Disease written by G. David Roodman and published by Springer Science & Business Media. This book was released on 2010-04-28 with total page 257 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents the forefront in the science and clinical management of myeloma bone disease. Coverage begins with sections on clinical presentation, imaging, and biochemical markers and goes on to discuss radiation, surgical, and medical therapies.

Author : S. Vincent Rajkumar
Publisher : Cambridge University Press
ISBN 13 : 1139473492
Total Pages : 207 pages
Book Rating : 4.91/5 ( download)

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Download or read book Treatment of Multiple Myeloma and Related Disorders written by S. Vincent Rajkumar and published by Cambridge University Press. This book was released on 2008-10-27 with total page 207 pages. Available in PDF, EPUB and Kindle. Book excerpt: Due to major advances in understanding the biology and pathogenesis of the disease, the management of multiple myeloma is changing rapidly. New diagnostic and prognostic criteria have been introduced, and treatment options are multiplying with high-dose chemotherapy regimens, stem cell transplants, and the development of novel agents and immune-based strategies that target tumor cells directly. This book is aimed at the practitioner who is looking to put these advances into clinical context. It will serve as an up-to-date resource for treatment of myeloma and related disorders. Chapters are written by international authorities and contain color photos, diagrams, and algorithms outlining preferred treatment strategies. Relevant scientific information is integrated throughout, but the focus here is on providing practical therapeutic guidance for oncologists and hematologists caring for myeloma patients. The book covers all myeloma subtypes and related disorders, including amyloidosis, Waldenstrom macroglobulinemia, plasmacytoma, MGUS, and POEMS syndrome.

Author : Gosta Gahrton
Publisher : CRC Press
ISBN 13 : 0340810106
Total Pages : 489 pages
Book Rating : 4.01/5 ( download)

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Download or read book Multiple Myeloma and Related Disorders written by Gosta Gahrton and published by CRC Press. This book was released on 2004-04-30 with total page 489 pages. Available in PDF, EPUB and Kindle. Book excerpt: During the past decade there has been an enormous increase in knowledge of multiple myeloma and related disorders, reflected in the publication of more than 5000 articles on the subject in scientific journals. Much of this has come about as new technologies have made it possible to refine studies on chromosomes and genes and to gain information about gene expression. It is therefore highly appropriate that this new comprehensive reference should appear at this time. The book covers the whole field of multiple myeloma, and also related diseases such as Waldemstr&öm&’s macroglobulinaemia, and incorporates both the basic science underlying the diseases and their clinical management. Each chapter has been written to &’stand alone&’, allowing the reader to dip into a particular subject and find information quickly without the need to browse through multiple chapters. In addition to the developments described above, all of which are considered here, many other approaches to targeted therapy are reviewed.

Author : Daniele Derudas
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.70/5 ( download)

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Download or read book Management of Renal Failure in Multiple Myeloma written by Daniele Derudas and published by . This book was released on 2020 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Multiple myeloma (MM) is a monoclonal plasma cell neoplasia that commonly involves the kidney. Renal impairment is a serious complication during the course of the disease, and it is associated with increased morbidity and mortality. The most frequent mechanism of injury is represented by the precipitation of monoclonal free light chains (FLCs) in the distal tubule of nephron, defining a dramatic condition known as light chain cast nephropathy (LCCN). A prompt and early identification of the cause of renal disease, particularly in case of acute kidney injury (AKI), is mandatory for its effective management, avoiding the development of chronic kidney disease (CKD). In case of LCCN, in order to achieve renal recovery, it is needed, besides preventive measures, urgent intervention based on vigorous rehydration, correction of precipitating factors and effective anti-plasma cell chemotherapy. Currently, the association of the Proteasome Inhibitor Bortezomib with high-dose of Dexamethasone represents the standard association in newly diagnosed patients. The addition of another drug such as Cyclophosphamide or an Immunomodulatory Drugs may improve FLCs reduction but could be toxic. Interesting is the role of the newest therapeutic agents, particularly anti-CD38 Monoclonal Antibodies, whose efficacy and tolerance have been documented in patients without renal impairment. Despite controversial results from randomized studies, recent data suggest that in patients with LCCN and AKI requiring dialysis the association of systemic therapy with an extra-corporeal approach of FLCs removal, may increase renal response recovery rates. In this chapter, it is summarized physio-pathological basis of MM renal impairment, clinical manifestations, diagnostic procedures, and therapeutic management, included autologous stem cell transplantation.

Author : Morie A. Gertz
Publisher : Springer Science & Business Media
ISBN 13 : 1461485207
Total Pages : 311 pages
Book Rating : 4.09/5 ( download)

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Download or read book Multiple Myeloma written by Morie A. Gertz and published by Springer Science & Business Media. This book was released on 2013-10-01 with total page 311 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a comprehensive, state-of-the-art guide to the diagnosis, treatment, and biology of multiple myeloma and related plasma disorders. Edited and written by a multidisciplinary group of recognized authorities from the Mayo Clinic, it presents clear guidelines on diagnosis and therapy and covers all aspects of multiple myeloma, from molecular classification and diagnosis, to risk stratification and therapy. Closely related plasma cell disorders such as solitary plasmacytoma, Waldenstrom macroglobulinemia, and light chain amyloidosis are discussed in detail as well. The book addresses often overlooked topics, including the role of radiation therapy, vertebral augmentation, and supportive care. Our understanding of this group of disorders is developing at an unprecedented rate, and Multiple Myeloma meets the need among oncologists and hematologists for a clear, timely, and authoritative resource on their biology, diagnosis, and treatment.

Author : Z.-H. Liui
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3318026514
Total Pages : 274 pages
Book Rating : 4.11/5 ( download)

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Download or read book Podocytopathy written by Z.-H. Liui and published by Karger Medical and Scientific Publishers. This book was released on 2014-05-16 with total page 274 pages. Available in PDF, EPUB and Kindle. Book excerpt: The podocyte is a key cell that forms the last barrier of the kidney filtration unit. One of the most exciting developments in the field of nephrology in the last decade has been the elucidation of its biology and its role in the pathophysiology of inherited and acquired glomerular disease, termed podocytopathy. In this publication, world-renowned experts summarize the most recent findings and advances in the field: they describe the unique biological features and injury mechanisms of the podocyte, novel techniques used in their study, and diagnosis and potential therapeutic approaches to glomerular diseases. Due to its broad scope, this publication is of great value not only for clinical nephrologists and researchers, but also for students, residents, fellows, and postdocs.

Author : Friedhelm Raue
Publisher : Springer Science & Business Media
ISBN 13 : 3642850731
Total Pages : 238 pages
Book Rating : 4.38/5 ( download)

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Download or read book Hypercalcemia of Malignancy written by Friedhelm Raue and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hypercalcemia is the most common life-threatening metabolic disorder associated with cancer. The pathophysiological, epidemiological and clinical aspects of hypercalcemia of malignancy are presented in this issue, with a focus on the recently discovered humoral factor responsible for the development of hypercalcemia. With a better understanding of the pathophysiology of this condition and the development of new potent drugs, capable of inhibiting bone resorption, especially bisphosphonates, the clinician will be more successful in correcting hypercalcemia in the great majority of patients.