Mammary Gland Development Methods And Protocols

Author : Finian Martin
Publisher : Humana
ISBN 13 : 9781493964734
Total Pages : 0 pages
Book Rating : 4.39/5 ( download)

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Download or read book Mammary Gland Development written by Finian Martin and published by Humana. This book was released on 2016-10-29 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides key molecular biological protocols and experimental strategies currently employed to study the various stages of mammary gland development. Chapters are divided into four parts covering genetically modified mouse models that exhibit prenatal and pubertal mammary gland phenotypes, 2D and 3D-model culture systems, methodologies for mammary stem cell isolation, and translational applications that provide a bridge between experimental studies of mammary gland development and the study of human breast cancer. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Mammary Gland Development: Methods and Protocols will be useful for researchers whose primary interest is in mammary gland development; developmental biologists, epithelial cell biologists, and those with an interest in molecular mechanisms underlying breast cancer.

Author : Maria del Mar Vivanco
Publisher : Humana
ISBN 13 : 9781493925186
Total Pages : 0 pages
Book Rating : 4.80/5 ( download)

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Download or read book Mammary Stem Cells written by Maria del Mar Vivanco and published by Humana. This book was released on 2015-06-04 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The identification of normal and breast cancer stem cells has offered a new vision of this heterogeneous disease and new hopes for its prognosis and treatment. This volume provides an overview of recent developments in mammary stem cell research and discusses the many varieties of approaches used by researchers to investigate the properties and functions of mammary stem cells. The beginning chapters provide readers with an introduction to mammary stem cells, and the processes used to characterize stem cells and isolate them via fluorescent activated cell sorting. The next few chapters discuss DNA and mRNA sequencing, proteomic techniques to help profile cells, lentiviral cell transduction for gene expression, and in vivo lineage tracing. The final few chapters are dedicated to following stem cells from their initial niche to the new microenvironment at their metastasis site, and to studying these cells using physical and mathematical approaches. Written in the highly successful Methods in Molecular Biology series format, the chapters include the kind of detailed description and implementation advice that is crucial for getting optimal results in the laboratory. Authoritative and cutting-edge, Mammary Stem Cells: Methods and Protocols aims to help members of the scientific community explore the behavior of stem cells and how to work with them in order to guide the design of new and complimentary strategies to be applied in the clinic with the ultimate end goal of fighting breast cancer.

Author : Maria del Mar Vivanco
Publisher : Humana
ISBN 13 : 9781493948499
Total Pages : 0 pages
Book Rating : 4.90/5 ( download)

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Download or read book Mammary Stem Cells written by Maria del Mar Vivanco and published by Humana. This book was released on 2016-10-09 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The identification of normal and breast cancer stem cells has offered a new vision of this heterogeneous disease and new hopes for its prognosis and treatment. This volume provides an overview of recent developments in mammary stem cell research and discusses the many varieties of approaches used by researchers to investigate the properties and functions of mammary stem cells. The beginning chapters provide readers with an introduction to mammary stem cells, and the processes used to characterize stem cells and isolate them via fluorescent activated cell sorting. The next few chapters discuss DNA and mRNA sequencing, proteomic techniques to help profile cells, lentiviral cell transduction for gene expression, and in vivo lineage tracing. The final few chapters are dedicated to following stem cells from their initial niche to the new microenvironment at their metastasis site, and to studying these cells using physical and mathematical approaches. Written in the highly successful Methods in Molecular Biology series format, the chapters include the kind of detailed description and implementation advice that is crucial for getting optimal results in the laboratory. Authoritative and cutting-edge, Mammary Stem Cells: Methods and Protocols aims to help members of the scientific community explore the behavior of stem cells and how to work with them in order to guide the design of new and complimentary strategies to be applied in the clinic with the ultimate end goal of fighting breast cancer.

Author : E. Anderson
Publisher : Springer
ISBN 13 : 9781461282570
Total Pages : 528 pages
Book Rating : 4.78/5 ( download)

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Download or read book Cellular and Molecular Biology of Mammary Cancer written by E. Anderson and published by Springer. This book was released on 2011-09-17 with total page 528 pages. Available in PDF, EPUB and Kindle. Book excerpt: The idea for this book arose during the 1985 Gordon Conference on "Mammary Gland Biology". New developments in the methodology of cell biology and the explosive growth of molecular biology had begun to impact upon our understanding of mammary gland growth and function. It seemed a propitious time for summarizing the current status of knowledge of the cell and molecular biology of mammary cancer and for attempting to outline future areas of concern and interest. The reviews presented here were completed by the Fall of 1986. Although new insights will surely continue to emerge, it is hoped that the material in this volume will form not only a current update but a basic core of information for future experiments. We have not attempted to cover all areas of mammary gland transformation. Those areas where recent detailed reviews are already available have been omitted. Also, the areas of normal gland development, cell ultrastructure, hormone responsiveness, chemotherapy and clinical aspects of mammary cancer have not been included. Instead, we have selected those areas where the development of new methodology, reagents and results have led to new ideas about mammary gland function and development as they are related to neoplasia.

Author : Edmund B. Rucker
Publisher :
ISBN 13 : 9781629488530
Total Pages : 0 pages
Book Rating : 4.34/5 ( download)

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Download or read book Mammary Glands written by Edmund B. Rucker and published by . This book was released on 2014 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a compilation of manuscripts that encompass a breadth of information from different species including rodents, dogs, cows, goats, and sheep. Normal developmental processes are covered and anatomical features are discussed, as well as the impact and significance of environmental chemicals and epigenetics on the mammary gland. In terms of disease states, cancer and mastitis are the most impactful in the fields of human medicine and livestock management, respectively, in the context of mammary gland biology. Therefore, this book presents in depth analyses of these diseases over several chapters and different model systems. Rodent and canine cancer models are discussed, which are very relevant in understanding the roles that genes and the environment play in human breast cancer. In the livestock industry, mastitis in the dairy sector has a deep economic impact globally, and results in over a billion dollar loss annually. Several chapters are devoted towards this disease in dairy cattle, sheep and goats, with an underlying theme of generating newer detection strategies to detect infections at an earlier stage. An up-to-date description of the most important signaling pathways and mechanisms that impact both development and disease are included. A gamut of sub-disciplines are found throughout the book that covers the main aspects of anatomy, physiology, cell biology, genetics, and molecular biology in both development and diseases of the mammary gland.

Author : Zuzana Sumbalova Koledova
Publisher : Springer Nature
ISBN 13 : 107163674X
Total Pages : 337 pages
Book Rating : 4.49/5 ( download)

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Download or read book 3D Cell Culture written by Zuzana Sumbalova Koledova and published by Springer Nature. This book was released on with total page 337 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Author : Monica Reynolds
Publisher : University of Pennsylvania Press
ISBN 13 : 1512806056
Total Pages : 284 pages
Book Rating : 4.52/5 ( download)

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Download or read book Lactogenesis written by Monica Reynolds and published by University of Pennsylvania Press. This book was released on 2016-11-11 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proceedings of a symposium, satellite to the 24th International Congress of Physiological Sciences, University of Pennsylvania.

Author : Jeffrey J. Zimmerman
Publisher : John Wiley & Sons
ISBN 13 : 1119350905
Total Pages : 1136 pages
Book Rating : 4.03/5 ( download)

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Download or read book Diseases of Swine written by Jeffrey J. Zimmerman and published by John Wiley & Sons. This book was released on 2019-03-25 with total page 1136 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides a fully revised Eleventh Edition of the definitive reference to swine health and disease Diseases of Swine has been the definitive reference on swine health and disease for over 60 years. This new edition has been completely revised to include the latest information, developments, and research in the field. Now with full color images throughout, this comprehensive and authoritative resource has been redesigned for improved consistency and readability, with a reorganized format for more intuitive access to information. Diseases of Swine covers a wide range of essential topics on swine production, health, and management, with contributions from more than 100 of the foremost international experts in the field. This revised edition makes the information easy to find and includes expanded information on welfare and behavior. A key reference for anyone involved in the swine industry, Diseases of Swine, Eleventh Edition: Presents a thorough revision to the gold-standard reference on pig health and disease Features full color images throughout the book Includes information on the most current advances in the field Provides comprehensive information on swine welfare and behavior Offers a reorganized format to make the information more accessible Written for veterinarians, academicians, students, and individuals and agencies responsible for swine health and public health, Diseases of Swine, Eleventh Edition is an essential guide to swine health.

Author : Kenneth S . Korach
Publisher : CRC Press
ISBN 13 : 9781420002898
Total Pages : 748 pages
Book Rating : 4.99/5 ( download)

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Download or read book Reproductive and Developmental Toxicology written by Kenneth S . Korach and published by CRC Press. This book was released on 1998-03-27 with total page 748 pages. Available in PDF, EPUB and Kindle. Book excerpt: This timely resource offers extensive discussions on the pharmacological, environmental,endocrinological, and natural factors that alter reproductive or developmental processes-elucidating the effects of toxicants on mechanisms of reproduction. Describing biological actions common to both genders as well as gender-specific processes, Reproducti

Author : National Cancer Institute (U.S.). Division of Cancer Cause and Prevention
Publisher :
ISBN 13 :
Total Pages : 496 pages
Book Rating : 4.49/5 ( download)

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Download or read book Report of the Carcinogenesis Program, Fiscal Year 1976 written by National Cancer Institute (U.S.). Division of Cancer Cause and Prevention and published by . This book was released on 1976 with total page 496 pages. Available in PDF, EPUB and Kindle. Book excerpt: