Life Science Data Mining

Author : Oliviero Carugo
Publisher : Humana
ISBN 13 : 9781493956883
Total Pages : 407 pages
Book Rating : 4.84/5 ( download)

DOWNLOAD NOW!

Download or read book Data Mining Techniques for the Life Sciences written by Oliviero Carugo and published by Humana. This book was released on 2016-08-23 with total page 407 pages. Available in PDF, EPUB and Kindle. Book excerpt: Most life science researchers will agree that biology is not a truly theoretical branch of science. The hype around computational biology and bioinformatics beginning in the nineties of the 20th century was to be short lived (1, 2). When almost no value of practical importance such as the optimal dose of a drug or the three-dimensional structure of an orphan protein can be computed from fundamental principles, it is still more straightforward to determine them experimentally. Thus, experiments and observationsdogeneratetheoverwhelmingpartofinsightsintobiologyandmedicine. The extrapolation depth and the prediction power of the theoretical argument in life sciences still have a long way to go. Yet, two trends have qualitatively changed the way how biological research is done today. The number of researchers has dramatically grown and they, armed with the same protocols, have produced lots of similarly structured data. Finally, high-throu- put technologies such as DNA sequencing or array-based expression profiling have been around for just a decade. Nevertheless, with their high level of uniform data generation, they reach the threshold of totally describing a living organism at the biomolecular level for the first time in human history. Whereas getting exact data about living systems and the sophistication of experimental procedures have primarily absorbed the minds of researchers previously, the weight increasingly shifts to the problem of interpreting accumulated data in terms of biological function and bio- lecular mechanisms.

Author : Jens Dörpinghaus
Publisher : Springer Nature
ISBN 13 : 303108411X
Total Pages : 593 pages
Book Rating : 4.19/5 ( download)

DOWNLOAD NOW!

Download or read book Computational Life Sciences written by Jens Dörpinghaus and published by Springer Nature. This book was released on 2023-03-04 with total page 593 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book broadly covers the given spectrum of disciplines in Computational Life Sciences, transforming it into a strong helping hand for teachers, students, practitioners and researchers. In Life Sciences, problem-solving and data analysis often depend on biological expertise combined with technical skills in order to generate, manage and efficiently analyse big data. These technical skills can easily be enhanced by good theoretical foundations, developed from well-chosen practical examples and inspiring new strategies. This is the innovative approach of Computational Life Sciences-Data Engineering and Data Mining for Life Sciences: We present basic concepts, advanced topics and emerging technologies, introduce algorithm design and programming principles, address data mining and knowledge discovery as well as applications arising from real projects. Chapters are largely independent and often flanked by illustrative examples and practical advise.

Author : Stephen T. C. Wong
Publisher : Science, Engineering, and Biol
ISBN 13 :
Total Pages : 394 pages
Book Rating : 4.74/5 ( download)

DOWNLOAD NOW!

Download or read book Life Science Data Mining written by Stephen T. C. Wong and published by Science, Engineering, and Biol. This book was released on 2006 with total page 394 pages. Available in PDF, EPUB and Kindle. Book excerpt: This timely book identifies and highlights the latest data mining paradigms to analyze, combine, integrate, model and simulate vast amounts of heterogeneous multi-modal, multi-scale data for emerging real-world applications in life science.The cutting-edge topics presented include bio-surveillance, disease outbreak detection, high throughput bioimaging, drug screening, predictive toxicology, biosensors, and the integration of macro-scale bio-surveillance and environmental data with micro-scale biological data for personalized medicine. This collection of works from leading researchers in the field offers readers an exceptional start in these areas.

Author : Oliviero Carugo
Publisher : Humana Press
ISBN 13 : 9781607614869
Total Pages : 408 pages
Book Rating : 4.63/5 ( download)

DOWNLOAD NOW!

Download or read book Data Mining Techniques for the Life Sciences written by Oliviero Carugo and published by Humana Press. This book was released on 2011-03-04 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: Most life science researchers will agree that biology is not a truly theoretical branch of science. The hype around computational biology and bioinformatics beginning in the nineties of the 20th century was to be short lived (1, 2). When almost no value of practical importance such as the optimal dose of a drug or the three-dimensional structure of an orphan protein can be computed from fundamental principles, it is still more straightforward to determine them experimentally. Thus, experiments and observationsdogeneratetheoverwhelmingpartofinsightsintobiologyandmedicine. The extrapolation depth and the prediction power of the theoretical argument in life sciences still have a long way to go. Yet, two trends have qualitatively changed the way how biological research is done today. The number of researchers has dramatically grown and they, armed with the same protocols, have produced lots of similarly structured data. Finally, high-throu- put technologies such as DNA sequencing or array-based expression profiling have been around for just a decade. Nevertheless, with their high level of uniform data generation, they reach the threshold of totally describing a living organism at the biomolecular level for the first time in human history. Whereas getting exact data about living systems and the sophistication of experimental procedures have primarily absorbed the minds of researchers previously, the weight increasingly shifts to the problem of interpreting accumulated data in terms of biological function and bio- lecular mechanisms.

Author : Chung-sheng Li
Publisher : World Scientific
ISBN 13 : 981447682X
Total Pages : 390 pages
Book Rating : 4.29/5 ( download)

DOWNLOAD NOW!

Download or read book Life Science Data Mining written by Chung-sheng Li and published by World Scientific. This book was released on 2006-12-29 with total page 390 pages. Available in PDF, EPUB and Kindle. Book excerpt: This timely book identifies and highlights the latest data mining paradigms to analyze, combine, integrate, model and simulate vast amounts of heterogeneous multi-modal, multi-scale data for emerging real-world applications in life science.The cutting-edge topics presented include bio-surveillance, disease outbreak detection, high throughput bioimaging, drug screening, predictive toxicology, biosensors, and the integration of macro-scale bio-surveillance and environmental data with micro-scale biological data for personalized medicine. This collection of works from leading researchers in the field offers readers an exceptional start in these areas.

Author : Rob Sullivan
Publisher : Springer Science & Business Media
ISBN 13 : 1597452904
Total Pages : 644 pages
Book Rating : 4.08/5 ( download)

DOWNLOAD NOW!

Download or read book Introduction to Data Mining for the Life Sciences written by Rob Sullivan and published by Springer Science & Business Media. This book was released on 2012-01-07 with total page 644 pages. Available in PDF, EPUB and Kindle. Book excerpt: Data mining provides a set of new techniques to integrate, synthesize, and analyze tdata, uncovering the hidden patterns that exist within. Traditionally, techniques such as kernel learning methods, pattern recognition, and data mining, have been the domain of researchers in areas such as artificial intelligence, but leveraging these tools, techniques, and concepts against your data asset to identify problems early, understand interactions that exist and highlight previously unrealized relationships through the combination of these different disciplines can provide significant value for the investigator and her organization.

Author : Li, Xiao-Li
Publisher : IGI Global
ISBN 13 : 1605663999
Total Pages : 450 pages
Book Rating : 4.99/5 ( download)

DOWNLOAD NOW!

Download or read book Biological Data Mining in Protein Interaction Networks written by Li, Xiao-Li and published by IGI Global. This book was released on 2009-05-31 with total page 450 pages. Available in PDF, EPUB and Kindle. Book excerpt: "The goal of this book is to disseminate research results and best practices from cross-disciplinary researchers and practitioners interested in, and working on bioinformatics, data mining, and proteomics"--Provided by publisher.

Author : Dwight McNeill
Publisher : Pearson Education
ISBN 13 : 0133407330
Total Pages : 351 pages
Book Rating : 4.34/5 ( download)

DOWNLOAD NOW!

Download or read book Analytics in Healthcare and the Life Sciences written by Dwight McNeill and published by Pearson Education. This book was released on 2014 with total page 351 pages. Available in PDF, EPUB and Kindle. Book excerpt: Make healthcare analytics work: leverage its powerful opportunities for improving outcomes, cost, and efficiency.This book gives you thepractical frameworks, strategies, tactics, and case studies you need to go beyond talk to action. The contributing healthcare analytics innovators survey the field's current state, present start-to-finish guidance for planning and implementation, and help decision-makers prepare for tomorrow's advances. They present in-depth case studies revealing how leading organizations have organized and executed analytic strategies that work, and fully cover the primary applications of analytics in all three sectors of the healthcare ecosystem: Provider, Payer, and Life Sciences. Co-published with the International Institute for Analytics (IIA), this book features the combined expertise of IIA's team of leading health analytics practitioners and researchers. Each chapter is written by a member of the IIA faculty, and bridges the latest research findings with proven best practices. This book will be valuable to professionals and decision-makers throughout the healthcare ecosystem, including provider organization clinicians and managers; life sciences researchers and practitioners; and informaticists, actuaries, and managers at payer organizations. It will also be valuable in diverse analytics, operations, and IT courses in business, engineering, and healthcare certificate programs.

Author : Xiaoli Li
Publisher : World Scientific
ISBN 13 : 9814551023
Total Pages : 436 pages
Book Rating : 4.21/5 ( download)

DOWNLOAD NOW!

Download or read book Biological Data Mining and Its Applications in Healthcare written by Xiaoli Li and published by World Scientific. This book was released on 2013-11-28 with total page 436 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biologists are stepping up their efforts in understanding the biological processes that underlie disease pathways in the clinical contexts. This has resulted in a flood of biological and clinical data from genomic and protein sequences, DNA microarrays, protein interactions, biomedical images, to disease pathways and electronic health records. To exploit these data for discovering new knowledge that can be translated into clinical applications, there are fundamental data analysis difficulties that have to be overcome. Practical issues such as handling noisy and incomplete data, processing compute-intensive tasks, and integrating various data sources, are new challenges faced by biologists in the post-genome era. This book will cover the fundamentals of state-of-the-art data mining techniques which have been designed to handle such challenging data analysis problems, and demonstrate with real applications how biologists and clinical scientists can employ data mining to enable them to make meaningful observations and discoveries from a wide array of heterogeneous data from molecular biology to pharmaceutical and clinical domains. Contents:Sequence Analysis:Mining the Sequence Databases for Homology Detection: Application to Recognition of Functions of Trypanosoma brucei brucei Proteins and Drug Targets (G Ramakrishnan, V S Gowri, R Mudgal, N R Chandra and N Srinivasan)Identification of Genes and Their Regulatory Regions Based on Multiple Physical and Structural Properties of a DNA Sequence (Xi Yang, Nancy Yu Song and Hong Yan)Mining Genomic Sequence Data for Related Sequences Using Pairwise Statistical Significance (Yuhong Zhang and Yunbo Rao)Biological Network Mining:Indexing for Similarity Queries on Biological Networks (Günhan Gülsoy, Md Mahmudul Hasan, Yusuf Kavurucu and Tamer Kahveci)Theory and Method of Completion for a Boolean Regulatory Network Using Observed Data (Takeyuki Tamura and Tatsuya Akutsu)Mining Frequent Subgraph Patterns for Classifying Biological Data (Saeed Salem)On the Integration of Prior Knowledge in the Inference of Regulatory Networks (Catharina Olsen, Benjamin Haibe-Kains, John Quackenbush and Gianluca Bontempi)Classification, Trend Analysis and 3D Medical Images:Classification and Its Application to Drug-Target Prediction (Jian-Ping Mei, Chee-Keong Kwoh, Peng Yang and Xiao-Li Li)Characterization and Prediction of Human Protein-Protein Interactions (Yi Xiong, Dan Syzmanski and Daisuke Kihara)Trend Analysis (Wen-Chuan Xie, Miao He and Jake Yue Chen)Data Acquisition and Preprocessing on Three Dimensional Medical Images (Yuhua Jiao, Liang Chen and Jin Chen)Text Mining and Its Biomedical Applications:Text Mining in Biomedicine and Healthcare (Hong-Jie Dai, Chi-Yang Wu, Richard Tzong-Han Tsai and Wen-Lian Hsu)Learning to Rank Biomedical Documents with Only Positive and Unlabeled Examples: A Case Study (Mingzhu Zhu, Yi-Fang Brook Wu, Meghana Samir Vasavada and Jason T L Wang)Automated Mining of Disease-Specific Protein Interaction Networks Based on Biomedical Literature (Rajesh Chowdhary, Boris R Jankovic, Rachel V Stankowski, John A C Archer, Xiangliang Zhang, Xin Gao, Vladimir B Bajic) Readership: Students, professionals, those who perform biological, medical and bioinformatics research. Keywords:Healthcare;Data Mining;Biological Data Mining;Protein Interactions;Gene Regulation;Text Mining;Biological Literature Mining;Drug Discovery;Disease Network;Biological Network;Graph Mining;Sequence Analysis;Structure Analysis;Trend Analysis;Medical ImagesKey Features:Each chapter of this book will include a section to introduce a specific class of data mining techniques, which will be written in a tutorial style so that even non-computational readers such as biologists and healthcare researchers can appreciate themThe book will disseminate the impact research results and best practices of data mining approaches to the cross-disciplinary researchers and practitioners from both the data mining disciplines and the life sciences domains. The authors of the book will be well-known data mining experts, bioinformaticians and cliniciansEach chapter will also provide a detailed description on how to apply the data mining techniques in real-world biological and clinical applications. Thus, readers of this book can easily appreciate the computational techniques and how they can be used to address their own research issues

Author :
Publisher :
ISBN 13 : 9781617795251
Total Pages : 656 pages
Book Rating : 4.59/5 ( download)

DOWNLOAD NOW!

Download or read book Introduction to Data Mining for the Life Sciences written by and published by . This book was released on 2012-01-01 with total page 656 pages. Available in PDF, EPUB and Kindle. Book excerpt: