Lean Manufacturing In Pharmaceutical Industry

Author : Ntin Kapoor
Publisher : Lulu.com
ISBN 13 : 1304064468
Total Pages : 37 pages
Book Rating : 4.62/5 ( download)

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Download or read book Lean Manufacturing In Pharmaceutical Industry written by Ntin Kapoor and published by Lulu.com. This book was released on 2013-11-20 with total page 37 pages. Available in PDF, EPUB and Kindle. Book excerpt: Due to the origin of Lean, it is widely used in manufacturing focussed companies like automotive industry but in current scenario the concept of Lean Manufacturing has been adopted by different businesses as well. In view of this, the objective of the report is to study the different approaches of Lean Manufacturing and the challenges which Pharma companies are facing in implementation of Lean Manufacturing and also the progress report of some companies to know whether any drug manufacture has truly made some progress or not.

Author : Bikash Chatterjee
Publisher : CRC Press
ISBN 13 : 1317180097
Total Pages : 173 pages
Book Rating : 4.98/5 ( download)

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Download or read book Applying Lean Six Sigma in the Pharmaceutical Industry written by Bikash Chatterjee and published by CRC Press. This book was released on 2016-04-08 with total page 173 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bikash Chatterjee emphasizes the criticality of applying the principles of Lean and Six Sigma within the paradigm of the drug development process. His guide to operational excellence in the pharmaceutical and biotech industries is a focused summary of the application of Lean Six Sigma theory to the regulated life sciences. From molecule discovery to the application of PAT Applying Lean Six Sigma in the Pharmaceutical Industry will highlight the importance of framing these initiatives within the key deliverables of drug development manufacturing and quality. Challenging conventional wisdom the author offers a quality and efficiency perspective as a foundation for the principles of Quality by Design, PAT and the new philosophies underlying Process Validation. Each chapter includes discussion around the considerations for applying Lean manufacturing and Six Sigma principles and their tools, culminating in a case study to illustrate the application. The book is organized to reflect the major work centers involved in the drug development lifecycle. Each chapter is stand-alone but together they illustrate the necessary synergy between Lean, Six Sigma and compliance sensibilities required to be successful in the pharmaceutical industry. These design, manufacturing and management techniques are not without their challenges. Bikash Chatterjee's book offers the roadmap for an industry that is struggling to reinvent many of its development and business processes.

Author : Peter L. King
Publisher : CRC Press
ISBN 13 : 0429681739
Total Pages : 373 pages
Book Rating : 4.38/5 ( download)

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Download or read book Lean for the Process Industries written by Peter L. King and published by CRC Press. This book was released on 2019-06-05 with total page 373 pages. Available in PDF, EPUB and Kindle. Book excerpt: Compared to its widespread implementation across almost all areas of production, Lean improvement efforts lag within the process industries. While many innovators have successfully applied Lean principles to these industries during the past three decades, most of those pioneering efforts were never recorded to guide the improvement efforts of others. Drawing on more than 40 years of application experience at one of the world’s largest chemical and materials manufacturers, coupled with 10 years in private practice, Peter King corrects this void by providing the first comprehensive resource written explicitly for change agents within the process industries. Focusing on areas where the improvement needs of the process industry differ from parts assembly manufacturing, Lean for the Process Industries: Dealing with Complexity, Second Edition: Covers each of the eight wastes commonly described in Lean literature, looking at how they manifest themselves in process operations. Explains how to adapt value stream mapping for process operations. Shows how to identify the root causes of bottlenecks, and how to manage them to optimize flow until they can be eliminated. Provides practical techniques to overcome the barriers which have prevented the application of Cellular Manufacturing to process operations. Discusses the role of business leadership in a Lean strategy, describing both enabling and counter-productive management behaviors Since the publication of the first edition of this book, Peter King has been busy consulting with food, beverage, gasoline additive, and nutraceutical companies -- these new experiences have broadened his perspectives on certain Lean processes and have given him a richer set of examples to discuss in this new edition. While Value Stream Mapping is a very powerful tool to understand flow, bottlenecks, and waste in an operation, the traditional format as presented in many other books does not describe all of the data required to fully understand process flow and its detractors. This new edition highlights the necessary additions with examples of why they are useful. Product wheel scheduling achieves production leveling in a far more comprehensive and effective way than traditional heijunka methods. This edition has a more thorough description of the wheel concept and design steps, and more examples from actual applications.

Author : Thomas Friedli
Publisher : Springer Science & Business Media
ISBN 13 : 3642351611
Total Pages : 536 pages
Book Rating : 4.17/5 ( download)

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Download or read book Leading Pharmaceutical Operational Excellence written by Thomas Friedli and published by Springer Science & Business Media. This book was released on 2013-11-26 with total page 536 pages. Available in PDF, EPUB and Kindle. Book excerpt: Achieving operational excellence is a challenge for the pharmaceutical industry, with many companies setting successful examples time and again. This book presents such leading practices for managing operational excellence throughout the pharmaceutical industry. Based on the St.Gallen OPEX Model the authors describe the current status of OPEX and the future challenges that have to be dealt with. The ample theoretical background is complemented hand-in-hand by case studies contributed by authors from leading pharmaceutical companies.​

Author : William Botha
Publisher :
ISBN 13 : 9780470411612
Total Pages : 336 pages
Book Rating : 4.19/5 ( download)

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Download or read book Lean Six Sigma in the Pharmaceutical Industry written by William Botha and published by . This book was released on 2013-07-19 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: Lean manufacturing focuses on speed, while traditional Six Sigma focuses on quality. Striking a perfect balance between these two business paradigms, Lean Six Sigma in the Pharmaceutical Industry introduces key lean six sigma principles to help readers improve the quality and efficiency of medical products and the predictability of supply chains. Rich with forms and charts, the book pharma companies and biotech industry professionals with an indispensable tool for implement a lean six sigma program internally rather than hiring an outside consulting firm.

Author : Terence Barnhart
Publisher : CRC Press
ISBN 13 : 1439800804
Total Pages : 267 pages
Book Rating : 4.05/5 ( download)

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Download or read book Creating a Lean R&D System written by Terence Barnhart and published by CRC Press. This book was released on 2012-08-20 with total page 267 pages. Available in PDF, EPUB and Kindle. Book excerpt: The ability to find and remove barriers between people and their systems in R&D can almost guarantee a doubling in performance, and often delivers multiples of that. R&D teams that have smooth handoffs deliver 100 percent of the required knowledge at those handoffs. As a result, such teams do not lose critical information, have unexpected k

Author : Nigel J Smart
Publisher : Elsevier
ISBN 13 : 1908818409
Total Pages : 384 pages
Book Rating : 4.09/5 ( download)

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Download or read book Lean Biomanufacturing written by Nigel J Smart and published by Elsevier. This book was released on 2013-10-31 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: With decreasing profit margins, increasing cost pressures, growing regulatory compliance concerns, mounting pressure from generic drugs and increasing anxiety about the future of healthcare reimbursement, pharmaceutical manufacturers are now forced to re-examine and re-assess the way they have been doing things. In order to sustain profitability, these companies are looking to reduce waste (of all kinds), improve efficiency and increase productivity. Many of them are taking a closer look at lean manufacturing as a way to achieve these goals. Lean biomanufacturing re-visits lean principles and then applies them sympathetically - in a highly practical approach - to the specific needs of pharmaceutical processes, which present significantly different challenges to more mainstream manufacturing processes. A major goal of the book is to highlight those problems and issues that appear more specific or unique to biopharmaceutical manufacturing situations and to provide some insights into what challenges are the important ones to solve and what techniques, tools and mechanisms to employ to be successful.Following an introduction to lean biomanufacturing, the book goes on to discuss lean technologies and methods applied in biomanufacturing. Later chapters cover the creation and implementation of the Transition Plan, issues facing the biopharmaceutical industry, creating a lean approach towards biopharmaceutical processes and the contribution of simulation models in developing these processes. The final chapter covers examples of new technology innovations which help facilitate lean biomanufacturing. A focus on the issues associated with the application of lean principles to biomanufacturing Practical examples of factors which can affect biopharmaceutical processes Coverage of key factors which require integration to run an efficient biopharmaceutical process

Author : Dennis P. Hobbs
Publisher : J. Ross Publishing
ISBN 13 : 9781932159141
Total Pages : 270 pages
Book Rating : 4.42/5 ( download)

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Download or read book Lean Manufacturing Implementation written by Dennis P. Hobbs and published by J. Ross Publishing. This book was released on 2003-09-15 with total page 270 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Lean Manufacturing Implementation Guide is a "how to" book that describes and documents the proven steps necessary to complete a successful lean transformation in a manufacturing facility. It reduces the manufacturer's fear of change by providing proven, objective and standard how to methods that are understandable and can be easily applied. The book is designed for manufacturing and engineering management personnel.

Author : Brad White
Publisher : CRC Press
ISBN 13 : 1315350734
Total Pages : 164 pages
Book Rating : 4.38/5 ( download)

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Download or read book Lean Daily Management for Healthcare written by Brad White and published by CRC Press. This book was released on 2016-08-19 with total page 164 pages. Available in PDF, EPUB and Kindle. Book excerpt: You likely don’t need any more tools, programs, or workshops to improve your hospital. What you need is a simple and consistent approach to manage problem-solving. Filling this need, this book presents a Lean management system that can help break down barriers between staff, directors, and administration and empower front-line staff to resolve their own problems. Lean Daily Management for Healthcare: A Strategic Guide to Implementing Lean for Hospital Leaders provides practical, step-by-step guidance on how to roll out Lean daily management in a hospital setting. Ideal for leaders that may feel lost in the transition process, the book supplies a roadmap to help you identify where your hospital currently is in its Lean process, where it’s headed, and how your role will change as you evolve into a Lean leader. Illustrating the entire process of implementing Lean daily management, the book breaks down the cultural progression of units into discreet, objectively measurable phases. It identifies what leaders at all levels of the organization must do to progress units into the next phase of development. Complete with case studies from different service areas in the hospital, the book explains how to link problem-solving boards together to achieve meaningful and measurable improvements in: the emergency department, the operating room, discharge times, clinics, quality, and patient satisfaction. After reading this book you will understand how consistent rounding, a few whiteboards, pen-and-paper data, and a focused effort on working the Plan-Do-Study-Act cycle can help you build a common problem-solving bench strength throughout your organization—establishing the framework upon which future improvement can be built.

Author : Fabrizio Giordanetto
Publisher : John Wiley & Sons
ISBN 13 : 3527801774
Total Pages : 816 pages
Book Rating : 4.70/5 ( download)

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Download or read book Early Drug Development written by Fabrizio Giordanetto and published by John Wiley & Sons. This book was released on 2018-06-15 with total page 816 pages. Available in PDF, EPUB and Kindle. Book excerpt: This one-stop reference systematically covers key aspects in early drug development that are directly relevant to the discovery phase and are required for first-in-human studies. Its broad scope brings together critical knowledge from many disciplines, ranging from process technology to pharmacology to intellectual property issues. After introducing the overall early development workflow, the critical steps of early drug development are described in a sequential and enabling order: the availability of the drug substance and that of the drug product, the prediction of pharmacokinetics and -dynamics, as well as that of drug safety. The final section focuses on intellectual property aspects during early clinical development. The emphasis throughout is on recent case studies to exemplify salient points, resulting in an abundance of practice-oriented information that is usually not available from other sources. Aimed at medicinal chemists in industry as well as academia, this invaluable reference enables readers to understand and navigate the challenges in developing clinical candidate molecules that can be successfully used in phase one clinical trials.