Laboratory Based Survey Of Acquired Hiv Drug Resistance Using Remnant Viral Load Specimens

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Publisher : World Health Organization
ISBN 13 : 9240025413
Total Pages : 91 pages
Book Rating : 4.17/5 ( download)

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Download or read book Laboratory-based survey of acquired HIV drug resistance using remnant viral load specimens written by and published by World Health Organization. This book was released on 2021-06-29 with total page 91 pages. Available in PDF, EPUB and Kindle. Book excerpt: WHO’s laboratory-based acquired drug resistance survey method yields robust estimates of acquired HIV drug resistance in adults, children and adolescents taking both dolutegravir and non-dolutegravir based regimens by genotyping remnant specimens from routine viral load testing. Results are used to inform programme decision making regarding optimal ART regimens and support evaluation of programme quality with respect to maximizing viral load suppression and minimizing emergence of resistance in people taking ART.

Author : World Health Organization
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.97/5 ( download)

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Download or read book LABORATORY-BASED SURVEY OF ACQUIRED HIV DRUG RESISTANCE USING REMNANT VIRAL LOAD SPECIMENS. written by World Health Organization and published by . This book was released on 2021 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Author : World Health Organization
Publisher : World Health Organization
ISBN 13 : 924006320X
Total Pages : 28 pages
Book Rating : 4.04/5 ( download)

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Download or read book Sentinel surveys of acquired HIV resistance to dolutegravir among people receiving dolutegravir-containing antiretroviral therapy written by World Health Organization and published by World Health Organization. This book was released on 2022-11-22 with total page 28 pages. Available in PDF, EPUB and Kindle. Book excerpt:

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Publisher : World Health Organization
ISBN 13 : 9240035001
Total Pages : 60 pages
Book Rating : 4.03/5 ( download)

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Download or read book Clinic-based survey of acquired HIV drug resistance written by and published by World Health Organization. This book was released on 2021-09-20 with total page 60 pages. Available in PDF, EPUB and Kindle. Book excerpt:

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Publisher : World Health Organization
ISBN 13 : 9240030565
Total Pages : 36 pages
Book Rating : 4.65/5 ( download)

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Download or read book HIV drug resistance strategy, 2021 update written by and published by World Health Organization. This book was released on 2020-07-23 with total page 36 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Author : World Health Organization
Publisher : World Health Organization
ISBN 13 : 9240076662
Total Pages : 30 pages
Book Rating : 4.62/5 ( download)

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Download or read book Target product profile for HIV drug resistance tests in low- and middle-income countries: Africa written by World Health Organization and published by World Health Organization. This book was released on 2023-09-12 with total page 30 pages. Available in PDF, EPUB and Kindle. Book excerpt: HIV-1 drug resistance tests may be useful tools for optimizing ART regimens when used in the context of information about viral load, immune and clinical status, adherence practices and available treatment options. Several types of drug resistance tests are available, either as commercial kits or based on published methods for in-house assays. The target product profile for HIV drug resistance tests in low- and middle-income countries: Africa is designed to guide the development of new HIV drug resistance tests in the era of dolutegravir-based antiretroviral therapy (ART) and to facilitate the evaluation of the suitability of currently available HIV drug resistance tests for specific applications. The target product profiles focus on the new-term future for available ART regimens and their use and anticipates an innovate test that will meet the projected demand.

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Publisher : World Health Organization
ISBN 13 : 924003854X
Total Pages : 22 pages
Book Rating : 4.47/5 ( download)

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Download or read book WHO HIV drug resistance network steering group meeting report June 2021 written by and published by World Health Organization. This book was released on 2021-11-22 with total page 22 pages. Available in PDF, EPUB and Kindle. Book excerpt:

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Publisher : World Health Organization
ISBN 13 : 9240038604
Total Pages : 138 pages
Book Rating : 4.08/5 ( download)

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Download or read book HIV drug resistance report 2021 written by and published by World Health Organization. This book was released on 2021-11-24 with total page 138 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Author : World Health Organization
Publisher : World Health Organization
ISBN 13 : 9240086315
Total Pages : 46 pages
Book Rating : 4.19/5 ( download)

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Download or read book HIV drug resistance written by World Health Organization and published by World Health Organization. This book was released on 2024-03-01 with total page 46 pages. Available in PDF, EPUB and Kindle. Book excerpt: This brief report summarizes recent information on HIV drug resistance (HIVDR) in the era of integrase-strand transfer inhibitors (INSTI) for HIV prevention and treatment. In this report, WHO documents high levels of HIV viral load suppression (>90%) in populations receiving dolutegravir (DTG)-containing antiretroviral therapy (ART). However, recent observational data reveal that HIVDR to DTG is emerging at levels exceeding those observed in clinical trials. Few countries have reported people not achieving viral suppression while receiving DTG-containing ART. However, amongst the surveys reported, levels of DTG resistance ranged from 3.9% to 8.6%, with levels as high as 19.6% observed among highly treatment-experienced people who transitioned to a DTG-containing ART while having high HIV viral loads. Levels of observed DTG resistance in real world populations receiving ART appear to be higher than anticipated from clinical trials. WHO recommends that countries routinely implement standardised surveillance of HIVDR to follow the prevalence and patterns of resistance among people not achieving suppressed viral load. The use of long acting cabotegravir (CAB-LA) for pre-exposure prophylaxis (PrEP) greatly reduces the risk of acquiring HIV. However, INSTI resistance has been observed in some cases with recent CAB-LA exposure, and delayed detection and confirmation of HIV infection can increase the risk of selection of INSTI drug resistance–associated mutations. Despite the possible risk, the roll-out of CAB-LA for PrEP should not be hindered. Scale-up of PrEP should be accompanied by standardized surveillance of drug resistance among people testing positive for HIV while receiving PrEP.

Author :
Publisher : World Health Organization
ISBN 13 : 9240019421
Total Pages : 40 pages
Book Rating : 4.23/5 ( download)

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Download or read book WHO HIVResNet meeting report, Johannesburg, South Africa, 19 October 2019 written by and published by World Health Organization. This book was released on 2021-02-15 with total page 40 pages. Available in PDF, EPUB and Kindle. Book excerpt: