Integrative Mechanobiology

Author : Yu Sun
Publisher : Cambridge University Press
ISBN 13 : 1316462544
Total Pages : 385 pages
Book Rating : 4.46/5 ( download)

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Download or read book Integrative Mechanobiology written by Yu Sun and published by Cambridge University Press. This book was released on 2015-11-12 with total page 385 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first of its kind, this comprehensive resource integrates cellular mechanobiology with micro-nano techniques to provide unrivalled in-depth coverage of the field, including state-of-the-art methods, recent advances, and biological discoveries. Structured in two parts, the first part offers detailed analysis of innovative micro-nano techniques including FRET imaging, electron cryo-microscopy, micropost arrays, nanotopography devices, laser ablation, and computational image analysis. The second part of the book provides valuable insights into the most recent technological advances and discoveries in areas such as stem cell, heart, bone, brain, tumor, and fibroblast mechanobiology. Written by a team of leading experts and well-recognised researchers, this is an essential resource for students and researchers in biomedical engineering.

Author : Przemyslaw Wojtaszek
Publisher : Springer Science & Business Media
ISBN 13 : 364219091X
Total Pages : 356 pages
Book Rating : 4.19/5 ( download)

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Download or read book Mechanical Integration of Plant Cells and Plants written by Przemyslaw Wojtaszek and published by Springer Science & Business Media. This book was released on 2011-06-28 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chemical reactions and interactions between molecules are commonly considered the basis of life, and thus the biochemical nature of cells and organisms is relatively well recognized. Research conducted in recent years, however, increasingly indicates that physical forces profoundly affect the functioning of life at all levels of its organization. To detect and to respond to such forces, plant cells and plants need to be structured mechanically. This volume focuses on mechanical aspects of plant life. It starts with a consideration of the mechanical integration of supracellular structures and mechanical properties of cellular building blocks to show how the structural integrity of plant cells is achieved and maintained during growth and development. The following chapters reveal how the functioning of integrated plant cells contributes to the mechanical integration of plants, and how the latter are able to detect physical stimuli and to reorganize their own cells in response to them. The mechanical aspects of plant responses to stresses are also presented. Finally, all these aspects are placed in an evolutionary context.

Author : Shu Chien
Publisher : Springer
ISBN 13 : 1493956175
Total Pages : 302 pages
Book Rating : 4.73/5 ( download)

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Download or read book Molecular and Cellular Mechanobiology written by Shu Chien and published by Springer. This book was released on 2016-08-10 with total page 302 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book will cover the cutting-edge developments in molecular and cellular mechanobiology to date. Readers will have a clear understanding of mechanobiology at the molecular and cellular levels, encompassing the mechanosensors, transducers, and transcription. An integrative approach across different scales from molecular sensing to mechanotransduction and gene modulation for physiological regulation of cellular functions will be explored, as well as applications to pathophysiological states in disease. A comprehensive understanding of the roles of physicochemical microenvironment and intracellular responses in determining cellular function in health and disease will also be discussed.

Author : Catherine Coutand
Publisher : Frontiers Media SA
ISBN 13 : 2889450740
Total Pages : 95 pages
Book Rating : 4.49/5 ( download)

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Download or read book Mechanical Signaling in Plants: From Perception to Consequences for Growth and Morphogenesis (Thigmomorphogenesis) and Ecological Significance written by Catherine Coutand and published by Frontiers Media SA. This book was released on 2017-01-27 with total page 95 pages. Available in PDF, EPUB and Kindle. Book excerpt: During the 1970s, renewed interest in plant mechanical signaling led to the discovery that plants subjected to mechanical stimulation develop shorter and thicker axes than undisturbed plants, a syndrome called thigmomorphogenesis. Currently, mechanosensing is being intensively studied because of its involvement in many physiological processes in plants and particularly in the control of plant morphogenesis. From an ecological point of view, the shaping of plant architecture has to be precisely organized in space to ensure light capture as well as mechanical stability. In natural environments terrestrial plants are subjected to mechanical stimulation mainly due to wind, but also due to precipitation, while aquatic and marine plants are subjected to current and wave energy. Plants acclimate to mechanically challenging environments by sensing mechanical stimulations and modifying their growth in length and diameter and their tissue properties to reduce potential for buckling or breakage. From a morphogenetic point of view, both external and internal mechanical cues play an important role in the control of cell division and meristem development likely by modulating microtubule orientation. How mechanical stimulations are being sensed by plants is an area of intense research. Different types of mechanosensors have been discovered or proposed, including ion channels gated by membrane tension (stretch activation) and plasma membrane receptor-like kinases that monitor the cell wall deformations. Electrophysiologists have measured the conductances of some stretch-activated channels and have showed that SAC of different structures can exhibit different conductances. The role of these differences in conductance has not yet been established. Once a mechanical stimulus has been perceived, it must be converted into a biological signal that can lead to variations of plant phenotype. Calcium has been shown to function as an early second messenger, tightly linked with changes in cytosolic and apoplastic pH. Transcriptional analyses of the effect of mechanical stimulation have revealed a considerable number of differentially expressed genes, some of which appear to be specific to mechanical signal transduction. These genes can thus serve as markers of mechanosensing, for example, in studies attempting to define signalling threshold, or variations of mechanosensitivity (accommodation). Quantitative biomechanical studies have lead to a model of mechanoperception which links mechanical state and plant responses, and provides an integrative tool to study the regulation of mechanosensing. This model includes parameters (sensitivity and threshold) that can be estimated experimentally. It has also been shown that plants are desensitized when exposed to multiple mechanical signals as a function of their mechanical history. Finally, mechanosensing is also involved in osmoregulation or cell expansion. The links between these different processes involving mechanical signalling need further investigation. This frontier research topic provides an overview of the different aspects of mechanical signaling in plants, spanning perception, effects on plant growth and morphogenesis, and broad ecological significance.

Author : Clark Spencer Larsen
Publisher : John Wiley & Sons
ISBN 13 : 1119828058
Total Pages : 677 pages
Book Rating : 4.51/5 ( download)

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Download or read book A Companion to Biological Anthropology written by Clark Spencer Larsen and published by John Wiley & Sons. This book was released on 2023-03-10 with total page 677 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Companion to Biological Anthropology The discipline of biological anthropology—the study of the variation and evolution of human beings and their evolutionary relationships with past and living hominin and primate relatives—has undergone enormous growth in recent years. Advances in DNA research, behavioral anthropology, nutrition science, and other fields are transforming our understanding of what makes us human. A Companion to Biological Anthropology provides a timely and comprehensive account of the foundational concepts, historical development, current trends, and future directions of the discipline. Authoritative yet accessible, this field-defining reference work brings together 37 chapters by established and younger scholars on the biological and evolutionary components of the study of human development. The authors discuss all facets of contemporary biological anthropology including systematics and taxonomy, population and molecular genetics, human biology and functional adaptation, early primate evolution, paleoanthropology, paleopathology, bioarchaeology, forensic anthropology, and paleogenetics. Updated and expanded throughout, this second edition explores new topics, revisits key issues, and examines recent innovations and discoveries in biological anthropology such as race and human variation, epidemiology and catastrophic disease outbreaks, global inequalities, migration and health, resource access and population growth, recent primate behavior research, the fossil record of primates and humans, and much more. A Companion to Biological Anthropology, Second Edition is an indispensable guide for researchers and advanced students in biological anthropology, geosciences, ancient and modern disease, bone biology, biogeochemistry, behavioral ecology, forensic anthropology, systematics and taxonomy, nutritional anthropology, and related disciplines.

Author : Xinyu Liu
Publisher : Academic Press
ISBN 13 : 0128242434
Total Pages : 406 pages
Book Rating : 4.38/5 ( download)

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Download or read book Micro and Nano Systems for Biophysical Studies of Cells and Small Organisms written by Xinyu Liu and published by Academic Press. This book was released on 2021-08-14 with total page 406 pages. Available in PDF, EPUB and Kindle. Book excerpt: Micro and Nano Systems for Biophysical Studies of Cells and Small Organisms provides a comprehensive introduction to the state-of-the-art micro and nano systems that have recently been developed and applied to biophysical studies of cells and small organisms. These micro and nano systems span from microelectromechanical systems (MEMS) and microfluidic devices to robotic micro-nanomanipulation systems. These biophysical studies range from cell mechanics to the neural science of worms and Drosophila. This book will help readers understand the fundamentals surrounding the development of these tools and teach them the most recent advances in cellular and organismal biophysics enabled by these technologies. Comprehensive coverage of micro and nano-system technology and application to biophysical studies of cells and small organisms. Highlights the most recent advances in cellular and organismal biophysics enabled by micro and nano systems. Insightful outlook on future directions and trends in each chapter covering a sub-area of the book topic.

Author : Jiro Nagatomi
Publisher : CRC Press
ISBN 13 : 0429816731
Total Pages : 960 pages
Book Rating : 4.34/5 ( download)

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Download or read book Mechanobiology Handbook, Second Edition written by Jiro Nagatomi and published by CRC Press. This book was released on 2018-12-07 with total page 960 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mechanobiology—the study of the effects of mechanics on biological events—has evolved to answer numerous research questions. Mechanobiology Handbook 2nd Edition is a reference book for engineers, scientists, and clinicians who are interested in mechanobiology and a textbook for senior undergraduate to graduate level students of this growing field. Readers will gain a comprehensive review of recent research findings as well as elementary chapters on solid mechanics, fluid mechanics, and molecular analysis techniques. The new edition presents, in addition to the chapters of the first edition, homework problem sets that are available online and reviews of research in uncovered areas. Moreover, the new edition includes chapters on statistical analysis, design of experiments and optical imaging. The editors of this book are researchers and educators in mechanobiology. They realized a need for a single volume to assist course instructors as a guide for didactic teaching of mechanobiology to a diverse student body. A mechanobiology course is frequently made up of both undergraduate and graduate students pursuing degrees in engineering, biology, or integrated engineering and biology. Their goal was to present both the elementary and cutting-edge aspects of mechanobiology in a manner that is accessible to students from many different academic levels and from various disciplinary backgrounds. Moreover, it is their hope that the readers of Mechanobiology Handbook 2nd Edition will find study questions at the end of each chapter useful for long-term learning and further discussion. Comprehensive collection of reviews of recent research Introductory materials in mechanics, biology, and statistics Discussion of pioneering and emerging mechanobiology concepts Presentation of cutting-edge mechanobiology research findings across various fields and organ systems End of chapter study questions, available online Considering the complexity of the mechanics and the biology of the human body, most of the world of mechanobiology remains to be studied. Since the field is still developing, the Mechanobiology Handbook raises many different viewpoints and approaches with the intention of stimulating further research endeavours.

Author : Yanhang Zhang
Publisher :
ISBN 13 : 9783030201838
Total Pages : 392 pages
Book Rating : 4.3X/5 ( download)

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Download or read book Multi-scale Extracellular Matrix Mechanics and Mechanobiology written by Yanhang Zhang and published by . This book was released on 2020 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the current state of knowledge in the field of multi-scale ECM mechanics and mechanobiology with a focus on experimental and modelling studies in biomechanical characterization, advanced optical microscopy and imaging, as well as computational modeling. This book also discusses the scale dependency of ECM mechanics, translation of mechanical forces from tissue to cellular level, and advances and challenges in improving our understanding of cellular mechanotransduction in the context of living tissues and organisms.

Author : Fritz-Albert Popp
Publisher : Springer Science & Business Media
ISBN 13 : 9401703736
Total Pages : 499 pages
Book Rating : 4.34/5 ( download)

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Download or read book Integrative Biophysics written by Fritz-Albert Popp and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 499 pages. Available in PDF, EPUB and Kindle. Book excerpt: Most of the specialists working in this interdisciplinary field of physics, biology, biophysics and medicine are associated with "The International Institute of Biophysics" (IIB), in Neuss, Germany, where basic research and possibilities for applications are coordinated. The growth in this field is indicated by the increase in financial support, interest from the scientific community and frequency of publications. Audience: The scientists of IIB have presented the most essential background and applications of biophotonics in these lecture notes in biophysics, based on the summer school lectures by this group. This book is devoted to questions of elementary biophysics, as well as current developments and applications. It will be of interest to graduate and postgraduate students, life scientists, and the responsible officials of industries and governments looking for non-invasive methods of investigating biological tissues.

Author : Jiro Nagatomi
Publisher : CRC Press
ISBN 13 : 042981674X
Total Pages : 705 pages
Book Rating : 4.41/5 ( download)

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Download or read book Mechanobiology Handbook, Second Edition written by Jiro Nagatomi and published by CRC Press. This book was released on 2018-12-07 with total page 705 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mechanobiology—the study of the effects of mechanics on biological events—has evolved to answer numerous research questions. Mechanobiology Handbook 2nd Edition is a reference book for engineers, scientists, and clinicians who are interested in mechanobiology and a textbook for senior undergraduate to graduate level students of this growing field. Readers will gain a comprehensive review of recent research findings as well as elementary chapters on solid mechanics, fluid mechanics, and molecular analysis techniques. The new edition presents, in addition to the chapters of the first edition, homework problem sets that are available online and reviews of research in uncovered areas. Moreover, the new edition includes chapters on statistical analysis, design of experiments and optical imaging. The editors of this book are researchers and educators in mechanobiology. They realized a need for a single volume to assist course instructors as a guide for didactic teaching of mechanobiology to a diverse student body. A mechanobiology course is frequently made up of both undergraduate and graduate students pursuing degrees in engineering, biology, or integrated engineering and biology. Their goal was to present both the elementary and cutting-edge aspects of mechanobiology in a manner that is accessible to students from many different academic levels and from various disciplinary backgrounds. Moreover, it is their hope that the readers of Mechanobiology Handbook 2nd Edition will find study questions at the end of each chapter useful for long-term learning and further discussion. Comprehensive collection of reviews of recent research Introductory materials in mechanics, biology, and statistics Discussion of pioneering and emerging mechanobiology concepts Presentation of cutting-edge mechanobiology research findings across various fields and organ systems End of chapter study questions, available online Considering the complexity of the mechanics and the biology of the human body, most of the world of mechanobiology remains to be studied. Since the field is still developing, the Mechanobiology Handbook raises many different viewpoints and approaches with the intention of stimulating further research endeavours.