Insights In Statistical Genetics And Methodology 2022

Author : Simon Charles Heath
Publisher : Frontiers Media SA
ISBN 13 : 283253645X
Total Pages : 172 pages
Book Rating : 4.52/5 ( download)

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Download or read book Insights in Statistical Genetics and Methodology: 2022 written by Simon Charles Heath and published by Frontiers Media SA. This book was released on 2023-10-24 with total page 172 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Research Topic is part of the Insights in Frontiers in Genetics series.

Author : Nan M. Laird
Publisher : Springer Science & Business Media
ISBN 13 : 1441973389
Total Pages : 226 pages
Book Rating : 4.82/5 ( download)

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Download or read book The Fundamentals of Modern Statistical Genetics written by Nan M. Laird and published by Springer Science & Business Media. This book was released on 2010-12-13 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers the statistical models and methods that are used to understand human genetics, following the historical and recent developments of human genetics. Starting with Mendel’s first experiments to genome-wide association studies, the book describes how genetic information can be incorporated into statistical models to discover disease genes. All commonly used approaches in statistical genetics (e.g. aggregation analysis, segregation, linkage analysis, etc), are used, but the focus of the book is modern approaches to association analysis. Numerous examples illustrate key points throughout the text, both of Mendelian and complex genetic disorders. The intended audience is statisticians, biostatisticians, epidemiologists and quantitatively- oriented geneticists and health scientists wanting to learn about statistical methods for genetic analysis, whether to better analyze genetic data, or to pursue research in methodology. A background in intermediate level statistical methods is required. The authors include few mathematical derivations, and the exercises provide problems for students with a broad range of skill levels. No background in genetics is assumed.

Author : Kenneth Lange
Publisher : Springer Science & Business Media
ISBN 13 : 9780387949093
Total Pages : 0 pages
Book Rating : 4.97/5 ( download)

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Download or read book Mathematical and Statistical Methods for Genetic Analysis written by Kenneth Lange and published by Springer Science & Business Media. This book was released on 1997 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: During the past decade, geneticists have constructed detailed maps of the human genome and cloned scores of Mendelian disease genes. These insights into human disease and evolution which have transformed medicine and agriculture depend on the contributions of applied mathematicians, statisticians, and computer scientists. This work is written to help readers understand and model the epidemiological and experimental data encountered in genetics research.

Author : Richard D. Emes
Publisher : Frontiers Media SA
ISBN 13 : 2832531733
Total Pages : 195 pages
Book Rating : 4.30/5 ( download)

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Download or read book Insights in Computational Genomics: 2022 written by Richard D. Emes and published by Frontiers Media SA. This book was released on 2023-08-15 with total page 195 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Research Topic is part of the Insights in Frontiers in Genetics series. Other titles in the series are: Genetics, Insights in Evolutionary and Population Genetics: 2022 Genetics, Insights in Livestock Genomics: 2022 Genetics, Insights in Epigenomics and Epigenetics: 2022 Genetics, Insights in Behavioral and Psychiatric Genetics: 2022 Genetics, Insights in Neurogenomics: 2022 Genetics, Insights in Genomic Assay Technology: 2022 Genetics, Insights in Genetics of Common and Rare Diseases: 2022 We are now entering the third decade of the 21st Century, and, especially in the last years, the achievements made by scientists have been exceptional, leading to major advancements in the fast-growing field of Genetics. Frontiers have organized a series of Research Topics to highlight the latest advancements in research across the field of Computational Genomics, with articles from the members of our accomplished Editorial Boards. This editorial initiative of particular relevance, led by Prof Richard Emes, Specialty Chief Editor of the Computational Genomics section, together with Dr. Pirooznia and Dr Zou, focused on new insights, novel developments, current challenges, latest discoveries, recent advances, and future perspectives in the field of Computational Genomics. The Research Topic solicits brief, forward-looking contributions from the editorial board members that describe the state of the art, outlining recent developments and major accomplishments that have been achieved and that need to occur to move the field forward. Authors are encouraged to identify the greatest challenges in the sub-disciplines, and how to address those challenges.

Author : Andrea S. Foulkes
Publisher : Springer Science & Business Media
ISBN 13 : 038789554X
Total Pages : 264 pages
Book Rating : 4.43/5 ( download)

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Download or read book Applied Statistical Genetics with R written by Andrea S. Foulkes and published by Springer Science & Business Media. This book was released on 2009-04-28 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: Statistical genetics has become a core course in many graduate programs in public health and medicine. This book presents fundamental concepts and principles in this emerging field at a level that is accessible to students and researchers with a first course in biostatistics. Extensive examples are provided using publicly available data and the open source, statistical computing environment, R.

Author : Jiajie Peng
Publisher : Frontiers Media SA
ISBN 13 : 2889761746
Total Pages : 160 pages
Book Rating : 4.46/5 ( download)

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Download or read book Data Mining and Statistical Methods for Knowledge Discovery in Diseases Based on Multimodal Omics written by Jiajie Peng and published by Frontiers Media SA. This book was released on 2022-06-06 with total page 160 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Author : Guanglin He
Publisher : Frontiers Media SA
ISBN 13 : 2832513670
Total Pages : 150 pages
Book Rating : 4.75/5 ( download)

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Download or read book Forensic Investigative Genetic Genealogy and Fine-Scale Structure of Human Populations written by Guanglin He and published by Frontiers Media SA. This book was released on 2023-02-03 with total page 150 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Author : Yuan-Ming Zhang
Publisher : Frontiers Media SA
ISBN 13 : 2832543693
Total Pages : 278 pages
Book Rating : 4.96/5 ( download)

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Download or read book Advances in Statistical Methods for the Genetic Dissection of Complex Traits in Plants written by Yuan-Ming Zhang and published by Frontiers Media SA. This book was released on 2024-01-26 with total page 278 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genome-wide association studies (GWAS) have been widely used in the genetic dissection of complex traits. However, there are still limits in current GWAS statistics. For example, (1) almost all the existing methods do not estimate additive and dominance effects in quantitative trait nucleotide (QTN) detection; (2) the methods for detecting QTN-by-environment interaction (QEI) are not straightforward and do not estimate additive and dominance effects as well as additive-by-environment and dominance-by-environment interaction effects, leading to unreliable results; and (3) no or too simple polygenic background controls have been employed in QTN-by-QTN interaction (QQI) detection. As a result, few studies of QEI and QQI for complex traits have been reported based on multiple-environment experiments. Recently, new statistical tools, including 3VmrMLM, have been developed to address these needs in GWAS. In 3VmrMLM, all the trait-associated effects, including QTN, QEI and QQI related effects, are compressed into a single effect-related vector, while all the polygenic backgrounds are compressed into a single polygenic effect matrix. These compressed parameters can be accurately and efficiently estimated through a unified mixed model analysis. To further validate these new GWAS methods, particularly 3VmrMLM, they should be rigorously tested in real data of various plants and a wide range of other species.

Author : Samuel A. Cushman
Publisher : Frontiers Media SA
ISBN 13 : 2832530133
Total Pages : 149 pages
Book Rating : 4.39/5 ( download)

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Download or read book Insights in evolutionary and population genetics: 2022 written by Samuel A. Cushman and published by Frontiers Media SA. This book was released on 2023-07-27 with total page 149 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Author : Guiyou Liu
Publisher : Frontiers Media SA
ISBN 13 : 2889768287
Total Pages : 222 pages
Book Rating : 4.88/5 ( download)

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Download or read book Systems Genetics of Human Complex Diseases - Volume II written by Guiyou Liu and published by Frontiers Media SA. This book was released on 2022-08-19 with total page 222 pages. Available in PDF, EPUB and Kindle. Book excerpt: