Inherited Cancer Syndromes

Author : B.A. Ponder
Publisher : Springer Science & Business Media
ISBN 13 : 9401106770
Total Pages : 222 pages
Book Rating : 4.71/5 ( download)

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Download or read book The Genetics of Cancer written by B.A. Ponder and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 222 pages. Available in PDF, EPUB and Kindle. Book excerpt: It has been recognized for almost 200 years that certain families seem to inherit cancer. It is only in the past decade, however, that molecular genetics and epidemiology have combined to define the role of inheritance in cancer more clearly, and to identify some of the genes involved. The causative genes can be tracked through cancer-prone families via genetic linkage and positional cloning. Several of the genes discovered have subsequently been proved to play critical roles in normal growth and development. There are also implications for the families themselves in terms of genetic testing with its attendant dilemmas, if it is not clear that useful action will result. The chapters in The Genetics of Cancer illustrate what has already been achieved and take a critical look at the future directions of this research and its potential clinical applications.

Author : Suzanne M. Mahon
Publisher :
ISBN 13 : 9781635930498
Total Pages : 0 pages
Book Rating : 4.99/5 ( download)

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Download or read book Understanding Genomic and Hereditary Cancer Risk written by Suzanne M. Mahon and published by . This book was released on 2021 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Collecting a family medical history is a regular component of the nursing assessment process that often includes information on familial cancer diagnoses, and patients may fear that they or their loved ones might be at increased risk for developing cancer because of hereditary factors. Although true inherited risk for developing cancer is much less common than acquired risk for developing cancer, approximately 10% of cancer diagnoses can be attributed to inherited risk. The identification of families exhibiting hereditary cancer syndromes enables individuals at risk to engage in increased surveillance and, in some cases, risk-reducing surgery and other preventive measures, which ultimately lead to decreasing the morbidity and mortality associated with a cancer diagnosis. The role of the nurse in helping patients to understand and manage hereditary cancer risk requires specialized knowledge of genetics and genomics concepts. Understanding Genomic and Hereditary Cancer Risk: A Handbook for Oncology Nurses provides background on basic genetic and genomic concepts, particularly those related to hereditary risk for developing cancer, to aid nurses in knowing when and why to refer patients. It also provides reliable information about how and why genetic and genomic testing can both aid in treatment decisions and also guide recommendations for cancer prevention and early detection. The nurse's role in genetic testing and counseling are discussed, as are questions and answers about types of testing, including direct-to-consumer genetic testing. Following genetic testing, most genetics professionals provide detailed information about recommendations for care, including recommendations for ongoing prevention and early detection. For patients who are found to have a harmful mutation, these recommendations can be extensive and are based on the personal and family medical history, as well as the specific variant. This book provides quick overviews of many of the more common hereditary variants as well as resources for more information. This handbook provides nurses with the essentials to understand genomic and hereditary cancer risk, to assist in facilitating interprofessional care with genetics and other oncology professionals, and to provide their patients with accurate and reassuring information"--

Author : Neal C. Jr. Ellis
Publisher : Springer Science & Business Media
ISBN 13 : 0387215964
Total Pages : 252 pages
Book Rating : 4.69/5 ( download)

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Download or read book Inherited Cancer Syndromes written by Neal C. Jr. Ellis and published by Springer Science & Business Media. This book was released on 2007-05-08 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt: Of the 8 million individuals living with cancer in the United States, up to 800,000 patients have a form of inherited cancer. Inherited cancer syndromes account for 5-10% of all cancers, as evidenced by recent advances in the understanding of such syndromes as Familial Polyposis Syndromes (FAP), Hereditary Nonpolyposis Colon Cancer (HPNCC), and the BRCA1 and 2 breast cancer susceptibility genes. Inherited Cancer Syndromes: Current Clinical Management provides the clinician with a valuable tool for all aspects of patient care in inherited syndromes. Comprehensive, timely chapters present the fundamental principles of genetic counseling and testing, ethical issues, medical-legal issues, and clinical management principles. Chapters on inherited breast cancer, colon cancer, urologic malignancies, gynecologic malignancies, and MEN syndromes provide state-of-the-art information on hereditary risk identification, assessment and management, the role of the genetic counselor, providing optimal patient care, and the important research on the horizon - all written by an expert group of surgical and medical oncologists. Inherited Cancer Syndromes: Current Clinical Management is an important and timely book for surgical oncologists, medical oncologists, radiation oncologists, general surgeons, colorectal surgeons, trainees in surgery and oncology, and genetic counselors.

Author : Karen H. Lu
Publisher : CRC Press
ISBN 13 : 9781420052879
Total Pages : 0 pages
Book Rating : 4.7X/5 ( download)

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Download or read book Hereditary Gynecologic Cancer written by Karen H. Lu and published by CRC Press. This book was released on 2008-08-26 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hereditary Gynecologic Cancer: Risk, Prevention and Management fills the need that exists for a book addressing highly relevant clinical issues associated with the new field of hereditary gynecologic cancers. Written with the clinician in mind, the authors will cover a broad range of topics, beginning with an overview discussing clinical relevance of hereditary ovarian and hereditary endometrial cancers. Succeeding sections will provide in-depth analyses of Hereditary Breast Ovarian Cancer Syndrome, Lynch Syndrome, and other syndromes with gynecologic cancer components, and genetic risk assessment. Hereditary Gynecologic Cancer: Risk, Prevention and Management: is the first clinically focused reference detailing gynecologic patient management issues of BRCA1 and BRCA2 mutation carriers includes a practical section on genetic risk assessment and genetic testing examines case studies to demonstrate management techniques and decision-making provides detailed discussion of ovarian cancer screening, prevention and risk reducing surgery

Author : Kathy Steligo
Publisher : JHU Press
ISBN 13 : 1421444259
Total Pages : 496 pages
Book Rating : 4.53/5 ( download)

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Download or read book Living with Hereditary Cancer Risk written by Kathy Steligo and published by JHU Press. This book was released on 2022-09-27 with total page 496 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This book provides a comprehensive overview of hereditary cancer for a general audience, with coverage of the genetic tests available for detecting risk for heritable cancers as well as options for medical and surgical treatment"--

Author : Sue Clark,
Publisher : tfm Publishing Limited
ISBN 13 : 1908986336
Total Pages : 257 pages
Book Rating : 4.37/5 ( download)

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Download or read book A Guide to Cancer Genetics in Clinical Practice written by Sue Clark, and published by tfm Publishing Limited. This book was released on 2009-05-01 with total page 257 pages. Available in PDF, EPUB and Kindle. Book excerpt: FIRST PRIZE Winner in the Oncology category of the 2010 BMA Medical Book Competition. Intensive research over the last fifteen years has yielded a vast expansion in our understanding of the role of inheritance and genetics in a variety of cancers. Several inherited conditions have been identified which result in a high risk of various cancers; some of these were previously recognized, but the genetic basis underlying them has now been elucidated. This knowledge is now entering the sphere of routine clinical care. Surgeons, gastroenterologists, gynaecologists, oncologists, endocrinologists and many others need an awareness of these disorders, an understanding of genetic testing and when it is indicated, and how to manage patients with inherited cancer predisposition and their families. This book covers the basic concepts of cancer genetics. The common inherited cancer syndromes are each dealt with in greater depth, with the current management outlined. This book is aimed at all clinicians who may encounter these conditions in their practice. It aims to facilitate identification of high-risk individuals and families, to inform interaction with geneticists and other subspecialists, to provide a basis for patient management and to stimulate interest in these fascinating conditions.

Author :
Publisher :
ISBN 13 : 9780199558391
Total Pages : 93 pages
Book Rating : 4.96/5 ( download)

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Download or read book Concise Handbook of Familial Cancer Susceptibility Syndromes written by and published by . This book was released on 2008 with total page 93 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Author : Osman Nuri Dilek
Publisher : Springer Nature
ISBN 13 : 3030668533
Total Pages : 512 pages
Book Rating : 4.32/5 ( download)

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Download or read book Prophylactic Surgery written by Osman Nuri Dilek and published by Springer Nature. This book was released on 2021-04-16 with total page 512 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume introduces the reader to the most important standards and principles of prophylactic surgery. After discussing the comparative effectiveness of screening in the treatment of hereditary cancer syndromes and evaluating genetic predisposition, the book moves on to address ethical, legal, social and cost-effectiveness dimensions of prophylactic surgery. With the aim of preventing hereditary predisposition syndromes, it also includes a chapter on the application of preventive surgery to all specific fields of surgery. Given its scope, the book will appeal to a broad readership, from experienced surgeons to students.

Author : William B. Coleman
Publisher : Academic Press
ISBN 13 : 0128132582
Total Pages : 634 pages
Book Rating : 4.86/5 ( download)

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Download or read book Essential Concepts in Molecular Pathology written by William B. Coleman and published by Academic Press. This book was released on 2019-11-23 with total page 634 pages. Available in PDF, EPUB and Kindle. Book excerpt: Essential Concepts in Molecular Pathology, Second Edition, offers an introduction to molecular genetics and the "molecular" aspects of human disease. The book illustrates how pathologists harness their understanding of these entities to develop new diagnostics and treatments for various human diseases. This new edition offers pathology, genetics residents, and molecular pathology fellows an advanced understanding of the molecular mechanisms of disease that goes beyond what they learned in medical and graduate school. By bridging molecular concepts of pathogenesis to the clinical expression of disease in cell, tissue and organ, this fully updated, introductory reference provides the background necessary for an understanding of today’s advances in pathology and medicine. Explains the practice of "molecular medicine" and the translational aspects of molecular pathology, including molecular diagnostics, molecular assessment and personalized medicine Orients non-pathologists on what pathologists look for and how they interpret their observational findings based on histopathology Provides the reader with what is missing from most targeted introductions to pathology—the cell biology behind pathophysiology

Author : Jian-Jun Wei
Publisher : Springer Nature
ISBN 13 : 3030686086
Total Pages : 442 pages
Book Rating : 4.86/5 ( download)

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Download or read book Practical Gynecologic Pathology written by Jian-Jun Wei and published by Springer Nature. This book was released on 2021-04-15 with total page 442 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book serves as a quick review or summary of major diagnostic challenges in gynecologic pathology and embraces a Q/A format by providing the desired diagnostic knowledge. It combines the diagnostic approach as it relates to morphology and the relevant ancillary tests which impact on clinical outcome or management. Each topic is written by subspecialty gynecological pathologists in the field in making this a valuable book for a broad spectrum of readers, particularly pathology trainees, junior pathologists and general practicing pathologists. These authors provide concise and accurate answers for a variety of common, yet challenging diagnostic scenarios that are relevant and frequently encountered in daily practice. The book walks readers through current topics, controversies and diagnostic dilemmas for common gynecologic diseases with morphologic features and key ancillary tests, richly illustrated with figures and tables. To reflex the current advances in diagnostic gynecological pathology, the topics are closely correlated with the updated disease classifications and diagnostic criteria, particularly those recognized by the World Health Organization. Practical Gynecologic Pathology provides a concise summary and review for some of the most difficult, prevailing and emerging concepts in gynecologic pathology.