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Author : Darryl Leon
Publisher :
ISBN 13 : 9780429134395
Total Pages : 490 pages
Book Rating : 4.98/5 ( download)
Download or read book In Silico Technologies in Drug Target Identification and Validation written by Darryl Leon and published by . This book was released on 2006 with total page 490 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Darryl Leon
Publisher : CRC Press
ISBN 13 : 1420015737
Total Pages : 510 pages
Book Rating : 4.37/5 ( download)
Download or read book In Silico Technologies in Drug Target Identification and Validation written by Darryl Leon and published by CRC Press. This book was released on 2006-06-13 with total page 510 pages. Available in PDF, EPUB and Kindle. Book excerpt: The pharmaceutical industry relies on numerous well-designed experiments involving high-throughput techniques and in silico approaches to analyze potential drug targets. These in silico methods are often predictive, yielding faster and less expensive analyses than traditional in vivo or in vitro procedures. In Silico Technologies in Drug Target Ide
Author : Jürgen Moll
Publisher :
ISBN 13 : 9781493991457
Total Pages : 318 pages
Book Rating : 4.50/5 ( download)
Download or read book Target Identification and Validation in Drug Discovery written by Jürgen Moll and published by . This book was released on 2019 with total page 318 pages. Available in PDF, EPUB and Kindle. Book excerpt: This second edition book explores breakthrough technologies in the field of drug target identification and validation. The volume emphasizes particularly revolutionary technologies, such as CRISPR-related screening, "big data," and in silico approaches, as well as in vivo applications of CRISPR and best uses of animal models in drug development. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Fully updated and authoritative, Target Identification and Validation in Drug Discovery: Methods and Protocols, Second Edition is an ideal guide for molecular and cellular biologists, pharmacologists, pathologists, bioinformaticians, clinical researchers, or investigators, as well as experts in other fields that need a quick overview of these state-of-the-art technologies.
Author : Marcus T. Scotti
Publisher : Springer Nature
ISBN 13 : 3030958957
Total Pages : 266 pages
Book Rating : 4.54/5 ( download)
Download or read book Drug Target Selection and Validation written by Marcus T. Scotti and published by Springer Nature. This book was released on 2022-05-17 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first book in the newly created book series, Computer-Aided Drug Discovery and Design, focuses on the computational aspects of early drug discovery, drug target identification, and validation. It revises current classical paradigms in target and phenotypic-based drug design with still ingrained approximations and concepts and discusses the research in the new network approach concept that include kinetic selectivity and metabolic analysis. Many often-overlooked approximations and concepts in drug discovery are fully covered. Drug Target Selection and Validation includes both introductory sections and research-based sections to be of use to both students and research scientists in drug discovery, design, kinetics and metabolic analysis. Pharmaceutical scientists, pharmaceutics, drug developers, pharmacologists, biomedical researchers in computer science, medicinal chemists, and precision medicine developers benefit from the information provided. The book concludes with a chapter on chemical and structural databases.
Author : Alleyn T. Plowright
Publisher : John Wiley & Sons
ISBN 13 : 3527345299
Total Pages : 396 pages
Book Rating : 4.98/5 ( download)
Download or read book Target Discovery and Validation written by Alleyn T. Plowright and published by John Wiley & Sons. This book was released on 2020-02-18 with total page 396 pages. Available in PDF, EPUB and Kindle. Book excerpt: The modern drug developers? guide for making informed choices among the diverse target identification methods Target Discovery and Validation: Methods and Strategies for Drug Discovery offers a hands-on review of the modern technologies for drug target identification and validation. With contributions from noted industry and academic experts, the book addresses the most recent chemical, biological, and computational methods. Additionally, the book highlights techologies that are applicable to ?difficult? targets and drugs directed at multiple targets, including chemoproteomics, activity-based protein profiling, pathway mapping, genome-wide association studies, and array-based profiling. Throughout, the authors highlight a range of diverse approaches, and target validation studies reveal how these methods can support academic and drug discovery scientists in their target discovery and validation research. This resource: -Offers a guide to identifying and validating targets, a key enabling technology without which no new drug development is possible -Presents the information needed for choosing the appropriate assay method from the ever-growing range of available options -Provides practical examples from recent drug development projects, e. g. in kinase inhibitor profiling Written for medicinal chemists, pharmaceutical professionals, biochemists, biotechnology professionals, and pharmaceutical chemists, Target Discovery and Validation explores the current methods for the identification and validation of drug targets in one comrpehensive volume. It also includes numerous practical examples.
Author : Simone Brogi
Publisher : Frontiers Media SA
ISBN 13 : 2889660575
Total Pages : 504 pages
Book Rating : 4.75/5 ( download)
Download or read book In Silico Methods for Drug Design and Discovery written by Simone Brogi and published by Frontiers Media SA. This book was released on 2020-10-09 with total page 504 pages. Available in PDF, EPUB and Kindle. Book excerpt: This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
Author : Houng-Yau Mei
Publisher : CRC Press
ISBN 13 : 9780203910696
Total Pages : 604 pages
Book Rating : 4.99/5 ( download)
Download or read book Integrated Drug Discovery Technologies written by Houng-Yau Mei and published by CRC Press. This book was released on 2002-03-19 with total page 604 pages. Available in PDF, EPUB and Kindle. Book excerpt: Integrated Drug Discovery Technologies provides a global overview of emerging drug development technologies by presenting and integrating new techniques from the disciplines of chemistry, biology, and computational sciences. It combines integration of contemporary mechanization with strategies in drug delivery. Topics include: functional genomics,
Author : Dhanasekaran Dharumadurai
Publisher :
ISBN 13 : 9781071617281
Total Pages : 747 pages
Book Rating : 4.81/5 ( download)
Download or read book Methods in Actinobacteriology written by Dhanasekaran Dharumadurai and published by . This book was released on 2022 with total page 747 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume details techniques on the study of Isolation, characterization, and exploration of actinobacteria in industrial, food, agricultural, and environmental microbiology. Chapters cover a wide range of basic and advanced techniques associated with research on isolation, characterization and identification of actinobacteria in soil, sediment, estuarine, water, Saltpan, Mangroves, plants, lichens, sea weeds, sea grass, animals-crab, snail, shrimp. Authoritative and cutting-edge, Methods in Actinobacteriology aims to be a useful practical guide to researches to help further their study in this field.
Author : Brian W. Metcalf
Publisher :
ISBN 13 : 9780123693938
Total Pages : 279 pages
Book Rating : 4.34/5 ( download)
Download or read book Target Validation in Drug Discovery written by Brian W. Metcalf and published by . This book was released on 2007 with total page 279 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work presents a comprehensive contemporary framework for approaching target validation in drug discovery. It begins with a detailed description of new enabling technologies, including aptamers, RNA interference, functional genomics, and proteomics. The next section looks at biologic drug development with in-depth discussion of lessons learned from such well-known cases as Erbitux, Herceptin, and Avastin. Additional targets known as "second generation" drugs, which can be identified when disease pathways are validated by biologics, present new possible small molecule therapeutics and serve as the focus of the final section of the book.
Author : Amalia Stefaniu
Publisher : BoD – Books on Demand
ISBN 13 : 1838800670
Total Pages : 192 pages
Book Rating : 4.73/5 ( download)
Download or read book Cheminformatics and its Applications written by Amalia Stefaniu and published by BoD – Books on Demand. This book was released on 2020-07-15 with total page 192 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cheminformatics has emerged as an applied branch of Chemistry that involves multidisciplinary knowledge, connecting related fields such as chemistry, computer science, biology, pharmacology, physics, and mathematical statistics.The book is organized in two sections, including multiple aspects related to advances in the development of informatic tools and their specific use in compound structure databases with various applications in life sciences, mainly in medicinal chemistry, for identification and development of new therapeutically active molecules. The book covers aspects related to genomic analysis, semantic similarity, chemometrics, pattern recognition techniques, chemical reactivity prediction, drug-likeness assessment, bioavailability, biological target recognition, machine-based drug discovery and design. Results from various computational tools and methods are discussed in the context of new compound design and development, sharing promising opportunities, and perspectives.
