Immune Mechanisms In Inflammatory Bowel Disease

Author : Richard Blumberg
Publisher : Springer Science & Business Media
ISBN 13 : 0387337784
Total Pages : 262 pages
Book Rating : 4.84/5 ( download)

DOWNLOAD NOW!

Download or read book Immune Mechanisms in Inflammatory Bowel Disease written by Richard Blumberg and published by Springer Science & Business Media. This book was released on 2007-02-26 with total page 262 pages. Available in PDF, EPUB and Kindle. Book excerpt: Immune Mechanisms in Inflammatory Bowel Disease is a highly, concise update of the most recent advances in the immunobiology, genetics and microbiology related to Inflammatory Bowel Disease. This book broadly treats the topics that lead to understanding of the pathogenesis of this disease in an organized, systematic approach.

Author : Stephan R. Targan
Publisher : John Wiley & Sons
ISBN 13 : 1444359118
Total Pages : 1429 pages
Book Rating : 4.14/5 ( download)

DOWNLOAD NOW!

Download or read book Inflammatory Bowel Disease written by Stephan R. Targan and published by John Wiley & Sons. This book was released on 2011-08-24 with total page 1429 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the state-of–the-art book on inflammatory bowel disease you have been waiting for Written and edited by international experts in gastroenterology this up-to-date volume provides a complete review of the basic science behind inflammatory bowel disease (IBD), as well as evidence-based clinical guidance on diagnosis, treatment and long-term management of IBD. In 50 chapters the authors cover the latest and most promising treatment modalities and the science behind them. There are chapters which cover the advances in the medical and surgical treatment of conditions such as Crohn's disease and ulcerative colitis, as well as chapters focusing on nutrition, imaging and complementary medicine. This is an invaluable information resource for all those in the medical team treating patients with IBD. Whether you are a gastroenterologist, gastrointestinal surgeon or GI nurse specialist this book deserves a place in your library.

Author : Sami Karoui
Publisher : BoD – Books on Demand
ISBN 13 : 953307891X
Total Pages : 348 pages
Book Rating : 4.15/5 ( download)

DOWNLOAD NOW!

Download or read book Inflammatory Bowel Disease written by Sami Karoui and published by BoD – Books on Demand. This book was released on 2012-01-27 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is dedicated to inflammatory bowel disease, and the authors discuss the advances in the pathogenesis of inflammatory bowel disease, as well as several new parameters involved in the etiopathogeny of Crohn's disease and ulcerative colitis, such as intestinal barrier dysfunction and the roles of TH 17 cells and IL 17 in the immune response in inflammatory bowel disease. The book also focuses on several relevant clinical points, such as pregnancy during inflammatory bowel disease and the health-related quality of life as an end point of the different treatments of the diseases. Finally, advances in management of patients with inflammatory bowel disease are discussed, especially in a complete review of the recent literature.

Author : R. Duchmann
Publisher : Springer Science & Business Media
ISBN 13 : 9780792387879
Total Pages : 246 pages
Book Rating : 4.72/5 ( download)

DOWNLOAD NOW!

Download or read book Mechanisms of Intestinal Inflammation written by R. Duchmann and published by Springer Science & Business Media. This book was released on 2004-04-30 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years considerable progress has been achieved in regard to our understanding of the induction and modulation of the immune response in the intestinal mucosa. It is clear that this mucosal immune reaction is predominantly steered by certain T-cell populations, which are characterized by their cytokine secretion profile. Less well known are the conditions under which the uptake and processing of a specific antigen leads to a certain immune response, whether it be protective, tolerant or inflammatory. However, here again distinct progress has been made in our understanding. Equally significant for immune regulation in the gut appears to be so-called innate immunity. Every shift of equilibrium in the highly regulated mucosal immune reaction is accompanied by an inflammatory reaction and destruction of the mucosa. In nearly all cases, this inflammatory response is dependent on the presence of bacterial intestinal flora. This book, the proceedings of Falk Symposium 133 on Mechanisms of Intestinal Inflammation: Implications for Therapeutic Intervention in IBD', held in Berlin, Germany, on 10-11 June 2003, summarizes present knowledge in the area of unspecific and specific immune reactions in the gut, recording the gaps in our knowledge and, in particular, presenting the possibilities of targeted intervention. The link to inflammatory bowel diseases - Crohn's disease and ulcerative colitis - is always in focus. Chapters by an international panel of basic scientists, clinical researchers and clinicians also record the problems which can originate through today's possible modulation of the immune reaction, setting the basis for review of clinical problems. This book is valuable readings for all scientists and physicians, who, from different perspectives, have an interest in research on IBD and in the clinical management of these diseases.

Author : Samuel Huber
Publisher : BoD – Books on Demand
ISBN 13 : 9535127543
Total Pages : 266 pages
Book Rating : 4.43/5 ( download)

DOWNLOAD NOW!

Download or read book New Insights into Inflammatory Bowel Disease written by Samuel Huber and published by BoD – Books on Demand. This book was released on 2016-10-26 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt: The incidence of chronic inflammatory and autoimmune diseases is steadily increasing. Inflammatory bowel disease (IBD) is one example of a chronic inflammatory disease, which primarily affects the intestine but may also affect extraintestinal organs. The exact pathogenesis of IBD is currently unknown. However, it is clear that the pathogenesis is complex, involving barrier defects, changes in the intestinal microbiome, and chronic immune activation. This book aims to summarize basic aspects of these complex interactions between barrier function, microbiome, and the immune system. Of note, there is currently no cure for IBD. However, several therapies have evolved in the last years, which are overall able to-at least temporarily-suppress IBD. These therapies and the underlying mechanism are discussed.

Author : Markus Meurath
Publisher : Eurekah.Com Incorporated
ISBN 13 : 9781587062322
Total Pages : pages
Book Rating : 4.21/5 ( download)

DOWNLOAD NOW!

Download or read book Immune Mechanisms In Inflammatory Bowel Disease written by Markus Meurath and published by Eurekah.Com Incorporated. This book was released on 2002 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Author : Derek J. Chadwick
Publisher : John Wiley & Sons
ISBN 13 : 0470090472
Total Pages : 238 pages
Book Rating : 4.73/5 ( download)

DOWNLOAD NOW!

Download or read book Inflammatory Bowel Disease written by Derek J. Chadwick and published by John Wiley & Sons. This book was released on 2005-06-10 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt: Inflammatory bowel disease (IBD) comprises a group of idiopathic diseases of the intestine characterized by chronic inflammation of the bowel with periods of exacerbation and remission. Although the exact cause of IBD remains undetermined, the condition appears to be related to a combination of genetic and environmental factors resulting in an aberrant activation of the mucosal immune system. This book contains a series of interdisciplinary discussions between clinical and basic scientists focusing on key issues such as: Epithelial cell and molecular biology, including apoptosis, necrosis and cell survival The role of bacterial milieu and mucosal bacteria in the IBD and of prebiotic and probiotic therapy The progress towards the identification of susceptibility genes and phenotype-determining genes The pharmacogenetics of IBD Mucosal immunology and therapeutic strategies stemming therefrom

Author : Amélia Sarmento
Publisher : Frontiers Media SA
ISBN 13 : 288945214X
Total Pages : 128 pages
Book Rating : 4.49/5 ( download)

DOWNLOAD NOW!

Download or read book Understanding Crohn's Disease: Immunity, Genes and Microbes written by Amélia Sarmento and published by Frontiers Media SA. This book was released on 2017-08-11 with total page 128 pages. Available in PDF, EPUB and Kindle. Book excerpt: Crohn's disease (CD) is a chronic, relapsing, inflammatory bowel disease resulting in considerable morbidity and reduced quality of life. Although still under intense debate, CD seems to result from an enhanced and uncontrolled immune response to the gut microbiota. CD is thought to be multifactorial depending on genetic and environmental determinants. In recent years, nearly 100 single nucleotide polymorphisms (SNPs) were associated with increased risk of developing CD (some of the SNPs also associated with susceptibility to ulcerative colitis, another type of IBD). These SNPs are mostly located in genes involved in innate and adaptive immunity mechanisms, such as autophagy, expression of pattern-recognition receptors and citokine signaling. Epigenetics is also probably playing a role in CD susceptibility, as it is sensitive to environmental conditions and may mediate gene-environment interactions. Environmental factors possibly involved in CD development include diet, gut microbiota composition and infection with specific pathogens, of which the most consistently associated to CD are Mycobacterium avium subsp. paratuberculosis and adherent-invasive Escherichia coli. This Topic aimed at bringing together contributions covering different genetic, epigenetic, immunological and microbial processes involved in the development of CD, helping to drive forward the understanding of CD immunopahtology.

Author : Masato Kusunoki
Publisher : Springer
ISBN 13 : 4431555226
Total Pages : 151 pages
Book Rating : 4.23/5 ( download)

DOWNLOAD NOW!

Download or read book Colitis-Associated Cancer written by Masato Kusunoki and published by Springer. This book was released on 2015-10-01 with total page 151 pages. Available in PDF, EPUB and Kindle. Book excerpt: As the number of patients with colitis-associated cancer (CAC) is on the increase, the purpose of this book is to review the latest topics concerning management of the disease. In recent years, the diagnostic power of endoscopy and molecular pathology has also grown tremendously, as a result of which they now have a far greater influence on the treatment of CAC. At the moment, appropriate monitoring programs for ulcerative colitis and Crohn’s disease remain uncertain. At the same time, the latest findings on DNA methylation and microRNAs hold the promise of making revolutionary changes in these areas. Moreover, recent drug advances in the treatment of inflammatory bowel diseases have changed surgical indications. On the other hand, the indication of mucosectomy on colorectal cancer in ulcerative colitis and prophylactic abdominoperineal resection for Crohn’s disease remain controversial. This book provides the latest information on the remaining issues of CAC from the point of view of expert surgeons.

Author : Soichiro Miura
Publisher : Morgan & Claypool Publishers
ISBN 13 : 1615041443
Total Pages : 125 pages
Book Rating : 4.42/5 ( download)

DOWNLOAD NOW!

Download or read book Intestinal Immune System written by Soichiro Miura and published by Morgan & Claypool Publishers. This book was released on 2011 with total page 125 pages. Available in PDF, EPUB and Kindle. Book excerpt: These negative regulatory mechanisms of the intestinal immune system are disturbed in certain disease conditions, causing the immunocompetent cells to respond to food components and commensal bacteria by becoming activated and to overproduce inflammatory cytokines and chemokines. These disease conditions include food allergies, such as celiac disease, and the inflammatory bowel diseases, such as ulcerative colitis and Crohn's disease, although their exact etiological mechanisms remain to be revealed. --Book Jacket.