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Author : Hélène D. Moreau
Publisher : Frontiers Media SA
ISBN 13 : 288976088X
Total Pages : 178 pages
Book Rating : 4.86/5 ( download)
Download or read book Immune Cell Migration in Health and Disease written by Hélène D. Moreau and published by Frontiers Media SA. This book was released on 2022-05-04 with total page 178 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Kenneth Murphy
Publisher : Garland Science
ISBN 13 : 9780815344575
Total Pages : pages
Book Rating : 4.70/5 ( download)
Download or read book Janeway's Immunobiology written by Kenneth Murphy and published by Garland Science. This book was released on 2010-06-22 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.
Author : Klaus Ley
Publisher : Frontiers Media SA
ISBN 13 : 2889194302
Total Pages : 109 pages
Book Rating : 4.08/5 ( download)
Download or read book Arrest chemokines written by Klaus Ley and published by Frontiers Media SA. This book was released on 2015-05-20 with total page 109 pages. Available in PDF, EPUB and Kindle. Book excerpt: Arrest chemokines are a small group of chemokines that promote leukocyte arrest from rolling by triggering rapid integrin activation. Arrest chemokines have been described for neutrophils, monocytes, eosinophils, naïve lymphocytes and effector memory T cells. Most arrest chemokines are immobilized on the endothelial surface by binding to heparin sulfate proteoglycans. Whether soluble chemokines can promote integrin activation and arrest is controversial (Alon-Gerszten). Many aspects of the signaling pathway from the GPCR chemokine receptor to integrin activation are the subject of active investigation. Leukocyte adhesion deficiency III is a human disease in which chemokine-triggered integrin activation is defective because of a mutation in the cytoskeletal protein kindlin-3. About 10 different such mutations have been described. The defects seen in patients with LAD-III elucidate the importance of rapid integrin activation for host defense in humans. We welcome reports that help clarifying this crucial first step in the process of leukocyte transendothelial migration.
Author : Anke Brüning-Richardson
Publisher : Springer
ISBN 13 : 9783031645310
Total Pages : 0 pages
Book Rating : 4.16/5 ( download)
Download or read book Cell Migration in Development, Health and Disease written by Anke Brüning-Richardson and published by Springer. This book was released on 2024-10-18 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook gives an insight into the importance of cell migration in health during development, wound healing and immune responses as well as in disease with particular focus on cancer. The reader will learn about the different ways cells migrate to allow cellular changes during development to occur, as well as responses to injury and threat by foreign invaders. Cell migration is a driver of invasion and ultimately metastasis in cancer and as such we will give examples from highly aggressive cancer such as brain tumours. The book also includes an introduction to mathematical modelling to predict cell migration, information on the development of software for analysis of data generated in 2D and 3D as well as recent developments in the investigations into cell migration using 3D bioprinting. This textbook will be a great learning tool for advanced undergraduate students and Master students with the relevant science degrees such as in cell biology, developmental biology, cancer research, and tumour biology.
Author : Raffaele Badolato
Publisher : Springer Science & Business Media
ISBN 13 : 376437442X
Total Pages : 249 pages
Book Rating : 4.26/5 ( download)
Download or read book Lymphocyte Trafficking in Health and Disease written by Raffaele Badolato and published by Springer Science & Business Media. This book was released on 2006-09-05 with total page 249 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book deals with the description of the role of chemokines in immune response and underlines potential targets of therapeutical intervention. It offers a series of international contributions of the most challenging aspects of lymphocyte migration in homeostasis and in disease, and has a special focus on diseases and targets of therapeutical intervention. The book will interest researchers and clinicians from inflammation research.
Author : Daniele D’Ambrosio
Publisher : Springer Science & Business Media
ISBN 13 : 1592594352
Total Pages : 283 pages
Book Rating : 4.51/5 ( download)
Download or read book Cell Migration in Inflammation and Immunity written by Daniele D’Ambrosio and published by Springer Science & Business Media. This book was released on 2008-02-02 with total page 283 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chemokines and their receptors play a central role in the pathogenesis of numerous, perhaps all, acute and chronic inflammatory diseases. About 50 distinct chemokines produced by a variety cell types and tissues either c- stitutively or in response to inflammatory stimuli are involved in a plethora of biological processes. These small secreted proteins exert their exquisitely variegated functions upon binding to a family of seven-transmembrane spanning G-protein coupled receptors (GPCRs) composed of almost 20 distinct entities. The biological activities of chemokines range from the control of leukocyte trafficking in basal and inflammatory conditions to the regulation of hema- poiesis, angiogenesis, tissue architecture, and organogenesis. The basis for such diversified activities rests, on one hand, upon the ubiquitous nature of chemokine production and chemokine receptor expression. Virtually every cell type can produce chemokines and expresses a unique combination of chemokine receptors. On the other hand, chemokine receptors make use of a flexible and complex network of intracellular signaling machineries that can regulate a variety of cellular functions ranging from cell migration, growth, and differentiation to death. As knowledge of the size of chemokine and chemokine receptor families rapidly reaches completeness, much is still to be uncovered in terms of fu- tional architecture of the chemokine system. The disparity between the large number of chemokines and that smaller number of receptors is balanced by the promiscuity in ligand–receptor interactions, with multiple chemokines binding to the same receptor and several chemokines binding to more than one receptor.
Author : Raffaele Badolato
Publisher : Birkhäuser
ISBN 13 : 9783764390853
Total Pages : 253 pages
Book Rating : 4.59/5 ( download)
Download or read book Lymphocyte Trafficking in Health and Disease written by Raffaele Badolato and published by Birkhäuser. This book was released on 2009-09-03 with total page 253 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book deals with the description of the role of chemokines in immune response and underlines potential targets of therapeutical intervention. It offers a series of international contributions of the most challenging aspects of lymphocyte migration in homeostasis and in disease, and has a special focus on diseases and targets of therapeutical intervention. The book will interest researchers and clinicians from inflammation research.
Author : Siamon Gordon
Publisher : John Wiley & Sons
ISBN 13 : 1555819192
Total Pages : 892 pages
Book Rating : 4.94/5 ( download)
Download or read book Myeloid Cells in Health and Disease written by Siamon Gordon and published by John Wiley & Sons. This book was released on 2020-07-10 with total page 892 pages. Available in PDF, EPUB and Kindle. Book excerpt: The structure, functions, and interactions of myeloid cells have long been the focus of research and therapeutics development. Yet, much more remains to be discovered about the complex web of relationships that makes up the immune systems of animals. Scientists today are applying genome-wide analyses, single-cell methods, gene editing, and modern imaging techniques to reveal new subclasses of differentiated myeloid cells, new receptors and cytokines, and important interactions among immune cells. In Myeloid Cells in Health and Disease: A Synthesis, Editor Siamon Gordon has assembled an international team of esteemed scientists to provide their perspectives of myeloid cells during innate and adaptive immunity. The book begins by presenting the foundational research of Paul Ehrlich, Elie Metchnikoff, and Donald Metcalf. The following chapters discuss evolution and the life cycles of myeloid cells; specific types of differentiated myeloid cells, including macrophage differentiation; and antigen processing and presentation. The rest of the book is organized by broad topics in immunology, including the recruitment of myeloid and other immune cells following microbial infection the role of myeloid cells in the inflammation process and the repair of damaged tissue the vast arsenal of myeloid cell secretory molecules, including metalloproteinases, tumor necrosis factor, histamine, and perforin receptors and downstream signaling pathways that are activated following ligand-receptor binding roles of myeloid cells during microbial and parasite infections contributions of myeloid cells in atherosclerosis myeloid-derived suppressor cells in tumor development and cancer Myeloid Cells in Health and Disease: A Synthesis will benefit graduate students and researchers in immunology, hematology, microbial pathogenesis, infectious disease, pathology, and pharmacology. Established scientists and physicians in these and related fields will enjoy the book's rich history of myeloid cell research and suggestions for future research directions and potential therapies.
Author : Bruce Alberts
Publisher :
ISBN 13 : 9780815332183
Total Pages : 0 pages
Book Rating : 4.81/5 ( download)
Download or read book Molecular Biology of The Cell written by Bruce Alberts and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Bernd Kaspers
Publisher : Academic Press
ISBN 13 : 0123972728
Total Pages : 456 pages
Book Rating : 4.29/5 ( download)
Download or read book Avian Immunology written by Bernd Kaspers and published by Academic Press. This book was released on 2012-12-02 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second edition of Avian Immunology provides an up-to-date overview of the current knowledge of avian immunology. From the ontogeny of the avian immune system to practical application in vaccinology, the book encompasses all aspects of innate and adaptive immunity in chickens. In addition, chapters are devoted to the immunology of other commercially important species such as turkeys and ducks, and to ecoimmunology summarizing the knowledge of immune responses in free-living birds often in relation to reproductive success. The book contains a detailed description of the avian innate immune system, encompassing the mucosal, enteric, respiratory and reproductive systems. The diseases and disorders it covers include immunodepressive diseases and immune evasion, autoimmune diseases, and tumors of the immune system. Practical aspects of vaccination are examined as well. Extensive appendices summarize resources for scientists including cell lines, inbred chicken lines, cytokines, chemokines, and monoclonal antibodies. The world-wide importance of poultry protein for the human diet, as well as the threat of avian influenza pandemics like H5N1 and heavy reliance on vaccination to protect commercial flocks makes this book a vital resource. This book provides crucial information not only for poultry health professionals and avian biologists, but also for comparative and veterinary immunologists, graduate students and veterinary students with an interest in avian immunology. With contributions from 33 of the foremost international experts in the field, this book provides the most up-to-date review of avian immunology so far Contains a detailed description of the avian innate immune system reviewing constitutive barriers, chemical and cellular responses; it includes a comprehensive review of avian Toll-like receptors Contains a wide-ranging review of the "ecoimmunology" of free-living avian species, as applied to studies of population dynamics, and reviews methods and resources available for carrying out such research
