Homeostasis

Author : Jay Schulkin
Publisher : MIT Press
ISBN 13 : 9780262194808
Total Pages : 332 pages
Book Rating : 4.05/5 ( download)

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Download or read book Rethinking Homeostasis written by Jay Schulkin and published by MIT Press. This book was released on 2003 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt: An overview of allostasis, the process by which the body maintains overall viability under normal and adverse conditions.

Author : J. Gordon Betts
Publisher :
ISBN 13 : 9781947172807
Total Pages : 0 pages
Book Rating : 4.08/5 ( download)

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Download or read book Anatomy and Physiology written by J. Gordon Betts and published by . This book was released on 2013-04-25 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Author : Jay Schulkin
Publisher : Cambridge University Press
ISBN 13 : 1316347702
Total Pages : 388 pages
Book Rating : 4.06/5 ( download)

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Download or read book Allostasis, Homeostasis, and the Costs of Physiological Adaptation written by Jay Schulkin and published by Cambridge University Press. This book was released on 2004-10-25 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: The concept of homeostasis, the maintenance of the internal physiological environment of an organism within tolerable limits, is well established in medicine and physiology. In contrast, allostasis is a relatively new idea of 'viability through change'. With allostatic regulation by cephalic involvement, the body adapts to potentially diverse and dangerous situations through the activation of neural, hormonal, or immunological mechanisms. Allostasis explains how regulatory events maintain organismic viability, or not, in diverse contexts with varying set points of bodily needs and competing motivations. This 2005 book introduces the concept of allostasis and sets it alongside traditional views of homeostasis. It addresses basic regulatory systems and examines the behavior of bodily regulation under duress. The basic concepts of physiological homeostasis are integrated with disorders like depression, stress, anxiety and addiction. It will therefore appeal to graduate students, medical students and researchers working in physiology, epidemiology, endocrinology, neuroendocrinology, neuroscience, and psychology.

Author : Detlev Boison
Publisher : Oxford University Press
ISBN 13 : 0199322295
Total Pages : 657 pages
Book Rating : 4.99/5 ( download)

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Download or read book Homeostatic Control of Brain Function written by Detlev Boison and published by Oxford University Press. This book was released on 2016 with total page 657 pages. Available in PDF, EPUB and Kindle. Book excerpt: Homeostatic Control of Brain Function offers a broad view of brain health and diverse perspectives for potential treatments, targeting key areas such as mitochondria, the immune system, epigenetic changes, and regulatory molecules such as ions, neuropeptides, and neuromodulators. Loss of homeostasis becomes expressed as a diverse array of neurological disorders. Each disorder has multiple comorbidities - with some crossing over several conditions - and often disease-specific treatments remain elusive. When current pharmacological therapies result in ineffective and inadequate outcomes, therapies to restore and maintain homeostatic functions can help improve brain health, no matter the diagnosis. Employing homeostatic therapies may lead to future cures or treatments that address multiple comorbidities. In an age where brain diseases such as Alzheimer's or Parkinson's are ever present, the incorporation of homeostatic techniques could successfully promote better overall brain health. Key Features include · A focus on the homeostatic controls that significantly depend on the way one lives, eats, and drinks. · Highlights from emerging research in non-pharmaceutical therapies including botanical medications, meditation, diet, and exercise. · Incorporation of homeostatic therapies into existing basic and clinical research paradigms. · Extensive scientific basic and clinical research ranging from molecules to disorders. · Emerging practical information for improving homeostasis. · Examples of homeostatic therapies in preventing and delaying dysfunction. Both editors, Detlev Boison and Susan Masino, bring their unique expertise in homeostatic research to the overall scope of this work. This book is accessible to all with an interest in brain health; scientist, clinician, student, and lay reader alike.

Author : Laurival Antonio De Luca Jr.
Publisher : CRC Press
ISBN 13 : 1466506938
Total Pages : 340 pages
Book Rating : 4.30/5 ( download)

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Download or read book Neurobiology of Body Fluid Homeostasis written by Laurival Antonio De Luca Jr. and published by CRC Press. This book was released on 2013-10-01 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt: A timely symposium entitled Body-Fluid Homeostasis: Transduction and Integration was held at Araraquara, São Paulo, Brazil in 2011. This meeting was convened as an official satellite of a joint gathering of the International Society for Autonomic Neuroscience (ISAN) and the American Autonomic Society (AAS) held in Buzios, Rio de Janeiro. Broad international participation at this event generated stimulating discussion among the invited speakers, leading to the publication of Neurobiology of Body Fluid Homeostasis: Transduction and Integration. Drawn from the proceedings and filled with rich examples of integrative neurobiology and regulatory physiology, this volume: Provides updated research using human and animal models for the control of bodily fluids, thirst, and salt appetite Explores neural and endocrine control of body fluid balance, arterial pressure, thermoregulation, and ingestive behavior Discusses recent developments in molecular genetics, cell biology, and behavioral plasticity Reviews key aspects of brain serotonin and steroid and peptide control of fluid consumption and arterial pressure The book highlights research conducted by leading scientists on signal transduction and sensory afferent mechanisms, molecular genetics, perinatal and adult long-term influences on regulation, central neural integrative circuitry, and autonomic/neuroendocrine effector systems. The findings discussed by the learned contributors are relevant for a basic understanding of disorders such as heat injury, hypertension, and excess salt intake. A unique reference on the neurobiology of body fluid homeostasis, this volume is certain to fuel additional research and stimulate further debate on the topic.

Author : Tonks Fawcett
Publisher : Routledge
ISBN 13 : 1136475613
Total Pages : 132 pages
Book Rating : 4.10/5 ( download)

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Download or read book Pathophysiology, Homeostasis and Nursing written by Tonks Fawcett and published by Routledge. This book was released on 2014-06-03 with total page 132 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nursing students quite often find it difficult to relate what they learn with respect to normal and abnormal physiology to patient care. In this useful text Roger Watson and Tonks Fawcett clearly explain: * the concept of homeostasis * the relevance of physiology to common disorders * the patient's response to these disorders * the appropriate nursing response. Each chapter is presented in a standard format with a brief outline of the relevant normal physiology and how homeostatic mechanisms normally cope. The student is led to understand what the patient with a specific disorder feels like and why, and is clearly instructed in what nursing action to take. Pathophysiology, Homeostasis and Nursing shows clearly how understanding physiology can improve nursing care and covers the main issues that relate to basic observations. It includes questions to help the reader test their knowledge as they go along and provides an accessible concise text for health care students, particularly nurses.

Author : Manos Tsakiris
Publisher : Oxford University Press, USA
ISBN 13 : 0198811934
Total Pages : 369 pages
Book Rating : 4.30/5 ( download)

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Download or read book The Interoceptive Mind written by Manos Tsakiris and published by Oxford University Press, USA. This book was released on 2018-10-11 with total page 369 pages. Available in PDF, EPUB and Kindle. Book excerpt: Interoception is the body-to-brain axis of sensations that originates from the internal body and visceral organs. It plays a unique role in ensuring homeostasis, allowing human beings to experience and perceive the state of their bodies at any one time. However, interoception is rapidly gaining interest amongst those studying the human mind. It is believed that beyond homeostasis interoception is fundamental in understanding human emotion and motivation and their impact upon behavior. That link between interoception and self-awareness is supported by a growing body of experimental findings. The Interoceptive Mind: From Homeostasis to Awareness offers a state-of-the-art overview of, and insights into, the role of interoception for mental life, awareness, subjectivity, affect, and cognition. Structured across three parts, this multidisciplinary volume highlights the role that interoceptive signals, and our awareness of them, play in our mental life. It considers deficits in interoceptive processing and awareness in various mental health conditions. But it also considers the equally important role of interoception for well-being, approaching interoception from both a theoretical and a philosophical perspective. Written by leading experts in their fields, all chapters within this volume share a common concern for what it means to experience oneself, for the crucial role of emotions, and for issues of health and wellbeing. Each of those concerns is discussed on the joint basis of our bodily existence and interoception. The research presented here will undoubtedly accelerate the much-anticipated coming of age of interoceptive research in psychology, cognitive neurosciences and philosophy, making this vital reading for anyone working in those fields.

Author : Franck Mauvais-Jarvis
Publisher : Springer
ISBN 13 : 3319701789
Total Pages : 627 pages
Book Rating : 4.83/5 ( download)

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Download or read book Sex and Gender Factors Affecting Metabolic Homeostasis, Diabetes and Obesity written by Franck Mauvais-Jarvis and published by Springer. This book was released on 2017-12-08 with total page 627 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book provides a reference for years to come, written by world-renowned expert investigators studying sex differences, the role of sex hormones, the systems biology of sex, and the genetic contribution of sex chromosomes to metabolic homeostasis and diseases. In this volume, leaders of the pharmaceutical industry present their views on sex-specific drug discovery. Many of the authors presented at the Keystone Symposium on “Sex and gender factors affecting metabolic homeostasis, diabetes and obesity” to be held in March 2017 in Lake Tahoe, CA. This book will generate new knowledge and ideas on the importance of gender biology and medicine from a molecular standpoint to the population level and to provide the methods to study them. It is intended to be a catalyst leading to gender-specific treatments of metabolic diseases. There are fundamental aspects of metabolic homeostasis that are regulated differently in males and females, and influence both the development of diabetes and obesity and the response to pharmacological intervention. Still, most preclinical researchers avoid studying female rodents due to the added complexity of research plans. The consequence is a generation of data that risks being relevant to only half of the population. This is a timely moment to publish a book on sex differences in diseases as NIH leadership has asked scientists to consider sex as a biological variable in preclinical research, to ensure that women get the same benefit of medical research as men.

Author : Susanne Sattler
Publisher : Springer
ISBN 13 : 3319576135
Total Pages : 283 pages
Book Rating : 4.38/5 ( download)

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Download or read book The Immunology of Cardiovascular Homeostasis and Pathology written by Susanne Sattler and published by Springer. This book was released on 2017-06-30 with total page 283 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cardiovascular immunology is a newly emerging research area, investigating the crosstalk between the cardiovascular and the immune system. This crosstalk is evident through (1) crucial immunological capacities and functions of cardiovascular cell types, including cardiomyocytes, fibroblasts, endothelial cells, pericytes and cardiac resident macrophages, (2) the impact of aberrant immune function on the development of cardiovascular disease such as atherosclerosis, direct and indirect immune-mediated heart disease and vasculitis, and (3) the crucial role of the immune system in cardiac repair and regeneration. The Immunology of Cardiovascular Homeostasis and Pathology covers all these aspects of cardiovascular immunology, starting with homeostatic immunological functions of traditional cardiovascular cell types, and moving then to the role of the immune system in cardiovascular pathology and to recent research into targeting the immune system to boost cardiac healing and regeneration.

Author : Richard I. Morimoto
Publisher : Perspectives Cshl
ISBN 13 : 9781621822967
Total Pages : 562 pages
Book Rating : 4.66/5 ( download)

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Download or read book Protein Homeostasis, Second Edition written by Richard I. Morimoto and published by Perspectives Cshl. This book was released on 2019 with total page 562 pages. Available in PDF, EPUB and Kindle. Book excerpt: The entire life cycle of a protein-from synthesis and folding to transport and degradation-is carefully controlled by the proteostasis network. This network, consisting of many interconnected pathways and processes, manages protein homeostasis by dynamically responding to the needs of the cell. Stress and aging can challenge the proteostasis network, resulting in the aggregation of misfolded proteins-a feature of numerous neurodegenerative conditions. Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Biology provides a comprehensive update on how the proteostasis network functions in healthy cells and the diseases that result when protein quality control goes awry. The contributors examine the relevant biochemical attributes of proteins (e.g., solubility), the functions of normal protein aggregates (e.g., biofilm formation in bacteria), and the various heat shock proteins, chaperones, translocation machineries, proteasomes, signaling factors, and transcriptional programs involved in proteostasis. The roles of specific subcellular structures-the endoplasmic reticulum, mitochondria, ribosomes, lysosomes, and cytoplasm-in protein quality control are covered, as is the regulation of proteostasis at the organismal level (e.g., via neuronal activity). Discussions of the responses by cells when errors in protein quality control occur, the medical disorders that can result (e.g., Alzheimer disease), and pharmacologic approaches to ameliorate protein conformational disorders are also included. This book is therefore an essential reference for biochemists, cell biologists, and all biomedical scientists wishing to understand the pathological consequences of and potential therapies for proteostasis deficiencies in common human diseases.