Heat Shock Proteins In Veterinary Medicine And Sciences

Author : Alexzander A. A. Asea
Publisher : Springer
ISBN 13 : 331973377X
Total Pages : 398 pages
Book Rating : 4.77/5 ( download)

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Download or read book Heat Shock Proteins in Veterinary Medicine and Sciences written by Alexzander A. A. Asea and published by Springer. This book was released on 2018-03-21 with total page 398 pages. Available in PDF, EPUB and Kindle. Book excerpt: This books provides up-to-date reviews on current advances of the role of HSP in veterinary medicine and research. Key basic and clinical research laboratories from major universities, veterinary hospitals and pharmaceutical companies around the world have contributed chapters that review present research activity and importantly project this field into the future. For easy readability, the book is sub divided into sections on HSP in the following aspects of Veterinary Medicine, including, I - Domestic Animals, II - Poultry, III - Aquatic and IV - Parasites. The book is a must read for heat shock protein researchers in general and specifically those involved in clinical and research in veterinary medicine.

Author : Michael B. Evgen'ev
Publisher : Springer
ISBN 13 : 9401792356
Total Pages : 233 pages
Book Rating : 4.56/5 ( download)

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Download or read book Heat Shock Proteins and Whole Body Adaptation to Extreme Environments written by Michael B. Evgen'ev and published by Springer. This book was released on 2014-10-24 with total page 233 pages. Available in PDF, EPUB and Kindle. Book excerpt: For many years, the authors have investigated the adaptive role of heat shock proteins (HSPs) in different animals, including the representatives of homothermic and poikilothermic organisms that inhabit regions with contrasting thermal conditions. This book will summarize the data accumulated in the course of these studies and describe the general molecular mechanisms underlying the adaptation of various organisms to aggressive environments. We also concentrate on different evolutionary trends characteristic for HSP systems in the course of adaptation to fluctuating environmental conditions. In addition, we describe the peculiarities in the regulatory regions of heat shock genes necessary for fine tuning of these systems providing the adaptation to adverse conditions. Special emphasis is given to the role of mobile elements in the evolution and functioning of various groups of HSP genes. The book combines the results of field studies and laboratory analysis of stress genes systems.

Author : Michael B. Evgen'ev
Publisher : Springer
ISBN 13 : 9789401792363
Total Pages : 218 pages
Book Rating : 4.64/5 ( download)

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Download or read book Heat Shock Proteins and Whole Body Adaptation to Extreme Environments written by Michael B. Evgen'ev and published by Springer. This book was released on 2014-10-29 with total page 218 pages. Available in PDF, EPUB and Kindle. Book excerpt: For many years, the authors have investigated the adaptive role of heat shock proteins (HSPs) in different animals, including the representatives of homothermic and poikilothermic organisms that inhabit regions with contrasting thermal conditions. This book will summarize the data accumulated in the course of these studies and describe the general molecular mechanisms underlying the adaptation of various organisms to aggressive environments. We also concentrate on different evolutionary trends characteristic for HSP systems in the course of adaptation to fluctuating environmental conditions. In addition, we describe the peculiarities in the regulatory regions of heat shock genes necessary for fine tuning of these systems providing the adaptation to adverse conditions. Special emphasis is given to the role of mobile elements in the evolution and functioning of various groups of HSP genes. The book combines the results of field studies and laboratory analysis of stress genes systems.

Author : Stuart K. Calderwood
Publisher : Springer Science & Business Media
ISBN 13 : 1402064012
Total Pages : 399 pages
Book Rating : 4.12/5 ( download)

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Download or read book Heat Shock Proteins in Cancer written by Stuart K. Calderwood and published by Springer Science & Business Media. This book was released on 2007-09-09 with total page 399 pages. Available in PDF, EPUB and Kindle. Book excerpt: Heat shock proteins are emerging as important molecules in the development of cancer and as key targets in cancer therapy. These proteins enhance the growth of cancer cells and protect tumors from treatments such as drugs or surgery. However, new drugs have recently been developed particularly those targeting heat shock protein 90. As heat shock protein 90 functions to stabilize many of the oncogenes and growth promoting proteins in cancer cells, such drugs have broad specificity in many types of cancer cell and offer the possibility of evading the development of resistance through point mutation or use of compensatory pathways. Heat shock proteins have a further property that makes them tempting targets in cancer immunotherapy. These proteins have the ability to induce an inflammatory response when released in tumors and to carry tumor antigens to antigen presenting cells. They have thus become important components of anticancer vaccines. Overall, heat shock proteins are important new targets in molecular cancer therapy and can be approached in a number of contrasting approaches to therapy.

Author : Seiichi Uchiyama
Publisher : MDPI
ISBN 13 : 3039369407
Total Pages : 208 pages
Book Rating : 4.09/5 ( download)

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Download or read book Fluorescent polymers for sensing and imaging written by Seiichi Uchiyama and published by MDPI. This book was released on 2020-12-29 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nowadays, all scientists recognize that fluorescent probes play important roles in wide research areas, from chemistry to biology. By combining this fact with specific functional benefits from synthetic polymers, fluorescent polymeric probes are occasionally superior to small organic and inorganic fluorescent (or luminescent) probes in terms of sensitivity, robustness, and multiple functionality. The targets of fluorescent polymeric probes have extended from chemical species to physical parameter. This special issue is a platform for researches to develop a novel fluorescent polymeric probe and to establish a new analytical method using a conventional fluorescent polymeric probe. Related researches, e.g., fluorometric investigation of functional polymers, are also included.

Author : Alan Gunn
Publisher : John Wiley & Sons
ISBN 13 : 1119641225
Total Pages : 564 pages
Book Rating : 4.23/5 ( download)

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Download or read book Parasitology written by Alan Gunn and published by John Wiley & Sons. This book was released on 2022-06-14 with total page 564 pages. Available in PDF, EPUB and Kindle. Book excerpt: Parasitology Highly detailed textbook on parasites and parasite relationships The fully revised edition of Parasitology: An Integrated Approach holds true to its engaging and easy-to-read approach. It comprehensively covers the complex and dynamic interaction between the parasite and its host ranging from invertebrates to vertebrates. Following an integrated approach, the authors explain how the study of parasites requires an understanding of biological concepts such as growth and reproduction, molecular biology, biochemistry, immunology, and pathology. In this second edition, they further address parasites and parasite relationships in the grand scheme of global changes and their impact. This textbook also reviews the often-neglected positive aspects of parasite infections and how humans have used parasites for their own advantage. Parasitology: An Integrated Approach, 2nd edition includes supplementary learning resources such as self-assessment quizzes, practical exercises, and an extensive collection of photographs. Now includes parasite life cycles in colour Strong focus on parasite interactions with other pathogens such as bacteria and viruses Discusses major advancements in the field of parasite diagnostics Additional image material and learning resources (quizzes, practical exercises) provided online A valuable and comprehensive learning resource for undergraduate students in the biological, biomedical and veterinary sciences and in medicine. It is also of interest to postgraduates and professionals with an interest including but not limited to parasitology, animal welfare, ecology, and medical microbiology.

Author : Jerónimo Pan
Publisher : CRC Press
ISBN 13 : 0429678525
Total Pages : 737 pages
Book Rating : 4.23/5 ( download)

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Download or read book Marine Biology written by Jerónimo Pan and published by CRC Press. This book was released on 2022-03-02 with total page 737 pages. Available in PDF, EPUB and Kindle. Book excerpt: We present you with an updated reference book aimed for upper-level undergraduate and graduate students interested in Marine Biology. The textbook is designed to introduce the fundamentals of marine organisms and their ecological roles in the world’s oceans, and is organized by functional groups, emphasizing marine biodiversity rather than systematics or habitats. Each chapter has been written and peer-reviewed by renowned international experts in their respective fields, and includes updated information on relevant topics, from the microbial loop and primary production in the oceans, to marine megafauna and the impacts of projected climate change on marine life and ecosystems.

Author : Alexzander A. A. Asea
Publisher : Springer Nature
ISBN 13 : 3030622894
Total Pages : 297 pages
Book Rating : 4.93/5 ( download)

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Download or read book Heat Shock Proteins in Human Diseases written by Alexzander A. A. Asea and published by Springer Nature. This book was released on 2021-03-23 with total page 297 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book Heat Shock Proteins in Cancer Therapeutics provides the most comprehensive review on contemporary knowledge on the role of HSP in various types of cancer therapeutics. Using an integrative approach, the contributors provide a synopsis of the most current updates on the state of HSP in cancer therapeutics. The heat shock response pathway is a highly conserved cellular process. Heat shock factors are a master transcriptional regulator responsible for expression of several important heat shock proteins, which can effectively protect critical client proteins from misfolding and degradation, thus maintaining intracellular integrity under stressed conditions. Recent studies have demonstrated the direct connections between heat shock response players and tumor cell survival, validating heat shock response players as novel molecular targets in anticancer treatment. Although many hurdles in clinical application still need to be effectively addressed, such as undesirable drug toxicity and off target effects; narrow therapeutic window; poor PK/PD profiles, etc. Recent reports on synergistic drug combination, advanced prodrug design, smart nanoparticle packaging, and RNA aptamer selection offer promising solutions to overcome these challenges. Future advancements in this fast-growing area can potentially lead to the next generation of cancer therapeutics. Key basic and clinical research laboratories from major universities, academic medical hospitals, biotechnology and pharmaceutical laboratories around the world have contributed chapters that review present research activity and importantly project the field into the future. The book is a must read for graduate students. medical students, basic science researchers and postdoctoral scholars in the fields of Cancer Biology, Oncology, Translational Medicine, Clinical Research, Biotechnology, Cell & Molecular Medicine, Pharmaceutical Scientists and Researchers involved in Drug Discovery.

Author : Antonis Zampelas
Publisher : CRC Press
ISBN 13 : 1466580119
Total Pages : 340 pages
Book Rating : 4.14/5 ( download)

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Download or read book Antioxidants in Health and Disease written by Antonis Zampelas and published by CRC Press. This book was released on 2015-06-09 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt: Antioxidant use in health promotion and disease prevention either through dietary intake or supplementation is controversial. This book reviews the latest evidence-based research in the area, principally through prospective cohort studies and randomized controlled trials. It assesses major dietary antioxidants and discusses their use in diseases such as cancer, diabetes, stroke, coronary heart disease, HIV/AIDS, and neurodegenerative and immune diseases. The use of antioxidants in health is also discussed along with common adverse effects associated with antioxidant use.

Author : Ranbir Chander Sobti
Publisher : Academic Press
ISBN 13 : 0323910440
Total Pages : 504 pages
Book Rating : 4.46/5 ( download)

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Download or read book Advances in Animal Experimentation and Modeling written by Ranbir Chander Sobti and published by Academic Press. This book was released on 2021-12-08 with total page 504 pages. Available in PDF, EPUB and Kindle. Book excerpt: Exploration in Laboratory Animal Sciences Understanding Life Phenomena updates our knowledge about the newer technologies such as molecular biology, genomics including sequencing, proteomics, transcriptomics, cell culture, stem cell culture, transgenesis and their translation to understand systematics and phylogeny of laboratory animals at molecular level. In seven sections Exploration in Laboratory Animal Sciences Understanding Life Phenomena resolves issues of conservation, applications in environment monitoring, production of drugs and others. Comparative research has enabled use of domestic animal models that translate the advances in basic biosciences to the schemes for human welfare including medicine. Molecular geneticists are unravelling the complexities of mammalian genes and the field of biotechnology is maturing at a fast pace. Additionally, research focused on immunology and animal behavior offer new insight into ways of enhancing animal welfare. The rise in consumption of animal proteins in addition to the challenges of sustaining our natural resources has given animal scientists a vast array of opportunities to engage in integrative systems-based research for meeting the challenges that behold us. Exploration in Laboratory Animal Sciences Understanding Life Phenomena also discusses the manipulation of animals as factories for the production of safe foods, drugs, and sensors and others to meet the contemporary challenges faced by mankind in the new world order created by pandemic of Covid 19. It also includes several chapters on the causation and management of certain diseases and impact of microbes on life. Provides insight to newer and futuristic technologies to understand disease process and drug design by animal models Addresses a wide variety of species and covers a wide variety of topics (such as animal species, the laboratory setting, regulatory guidelines, and ethical considerations) to fully prepare for work with all types of animals Gives a perspective on laboratory animal use that allows to explain the benefits of animal use as required by veterinary technology program accreditation procedure Includes examples of animal bio-technological techniques (including stem cell and tissue engineering) for their applications to humanity Offers new insight into ways of enhancing animal welfare by the inclusion of research results focused on immunology and laboratory animal behavior