Handbook Of Pharmacokinetics

Author : Younggil Kwon
Publisher : Springer Science & Business Media
ISBN 13 : 0306468204
Total Pages : 302 pages
Book Rating : 4.09/5 ( download)

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Download or read book Handbook of Essential Pharmacokinetics, Pharmacodynamics and Drug Metabolism for Industrial Scientists written by Younggil Kwon and published by Springer Science & Business Media. This book was released on 2007-05-08 with total page 302 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the pharmaceutical industry, the incorporation of the disciplines of pharma- kinetics, pharmacodynamics, and drug metabolism (PK/PD/DM) into various drug development processes has been recognized to be extremely important for approp- ate compound selection and optimization. During discovery phases, the identifi- tion of the critical PK/PD/DM issues of new compounds plays an essential role in understanding their pharmacological profiles and structure-activity relationships. Owing to recent progress in analytical chemistry, a large number of compounds can be screened for their PK/PD/DM properties within a relatively short period of time. During development phases as well, the toxicology and clinical study designs and trials of a compound should be based on a thorough understanding of its PK/PD/DM properties. During my time as an industrial scientist, I realized that a reference work designed for practical industrial applications of PK/PD/DM could be a very valuable tool for researchers not only in the pharmacokinetics and drug metabolism departments, but also for other discovery and development groups in pharmaceutical companies. This book is designed specifically for industrial scientists, laboratory assistants, and managers who are involved in PK/PD/DM-related areas. It consists of thirteen chapters, each of which deals with a particular PK/PD/DM issue and its industrial applications. Chapters 3 and 12 in particular address recent topics on higher throughput in vivo exposure screening and the prediction of pharmacokinetics in humans, respectively. Chapter 8 covers essential information on drug metabolism for industrial scientists.

Author : Wolfgang A. Ritschel
Publisher :
ISBN 13 :
Total Pages : 616 pages
Book Rating : 4.58/5 ( download)

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Download or read book Handbook of Basic Pharmacokinetics-- Including Clinical Applications written by Wolfgang A. Ritschel and published by . This book was released on 1992 with total page 616 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Author : Mehdi Boroujerdi
Publisher : CRC Press
ISBN 13 : 1482221357
Total Pages : 538 pages
Book Rating : 4.50/5 ( download)

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Download or read book Pharmacokinetics and Toxicokinetics written by Mehdi Boroujerdi and published by CRC Press. This book was released on 2015-02-24 with total page 538 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pharmacokinetics and Toxicokinetics provides an overview of pharmacokinetics and toxicokinetics in a comprehensible, interrelated, and applied manner. It integrates the principles held in common by both fields through a logical and systematic approach. The book presents mathematical descriptions of physiological processes employed in different appr

Author : Siamak Cyrus Khojasteh
Publisher : Springer Science & Business Media
ISBN 13 : 1441956298
Total Pages : 222 pages
Book Rating : 4.93/5 ( download)

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Download or read book Drug Metabolism and Pharmacokinetics Quick Guide written by Siamak Cyrus Khojasteh and published by Springer Science & Business Media. This book was released on 2011-04-07 with total page 222 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug Metabolism and Pharmacokinetics Quick Guide covers a number of aspects of drug assessment at drug discovery and development stages, topics such as pharmacokinetics, absorption, metabolism, enzyme kinetics, drug transporters, drug interactions, drug-like properties, assays and in silico calculations. It covers key concepts, with useful tables on physiological parameters (eg. blood flow to organs in x-species, expression and localization of enzymes and transporters), chemical structure, nomenclature, and moieties leading to bioactivation (with examples). Overall it includes a number of key topics useful at the drug discovery stage, which would serve as a quick reference with several examples from the literature to illustrate the concept.

Author : David B. Jack
Publisher : Springer
ISBN 13 : 1349224952
Total Pages : 160 pages
Book Rating : 4.51/5 ( download)

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Download or read book Handbook of Clinical Pharmacokinetic Data written by David B. Jack and published by Springer. This book was released on 1992-12-18 with total page 160 pages. Available in PDF, EPUB and Kindle. Book excerpt: This compendium of essential drug data helps when planning clinical research projects and choosing drugs with specific properties. As well as covering established drugs, data is presented on compounds about to be marketed or in the last stages of clinical development.

Author : Biswajit Mukherjee
Publisher : Springer Nature
ISBN 13 : 9811689504
Total Pages : 354 pages
Book Rating : 4.05/5 ( download)

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Download or read book Pharmacokinetics: Basics to Applications written by Biswajit Mukherjee and published by Springer Nature. This book was released on 2022-03-17 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook covers all the essential elements of pharmacokinetics, from basics to applications. It describes authoritative equations and methods on pharmacokinetic evaluation procedures with their importance. Each chapter of the book is supplemented with numerous illustrations and figures for easy understanding of the subject. The book presents mathematical techniques, step- by-step descriptive equations, and applicable statistical analysis methods for the easy understanding of the topic. Further, it covers the preclinical applications and methods of pharmacokinetic aspects. The book also contains mathematical problems and questions related to pharmacokinetics for students. Special emphasis is on recent pharmacokinetic methods and their applications for managing clinical data and biostatistical approaches based on the current literature. This book is primarily meant for researchers and students from academic institutions and to R&D professionals.

Author : Larry Bauer
Publisher : McGraw-Hill Medical
ISBN 13 :
Total Pages : 502 pages
Book Rating : 4.27/5 ( download)

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Download or read book Clinical Pharmacokinetics Handbook written by Larry Bauer and published by McGraw-Hill Medical. This book was released on 2006 with total page 502 pages. Available in PDF, EPUB and Kindle. Book excerpt: Designed for pharmacists and clinicians responsible for adjusting drug dosages based on the patient blood serum concentrations and other parameters, this indispensable, portable reference offers a variety of ways to perform pharmacokinetic calculations. Features calculation methods, algorithms for choosing the best calculation method, and case studies.

Author : Hartmut Derendorf
Publisher : CRC Press
ISBN 13 : 9780849383038
Total Pages : 502 pages
Book Rating : 4.3X/5 ( download)

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Download or read book Handbook of Pharmacokinetic/Pharmacodynamic Correlation written by Hartmut Derendorf and published by CRC Press. This book was released on 1995-03-23 with total page 502 pages. Available in PDF, EPUB and Kindle. Book excerpt: Combining the established disciplines of pharmacokinetics (PK), the relationship between drug concentration and time, and pharmacodynamics (PD), the relationship between drug effects and concentration, this handbook examines the relevant relationship between drug effects and time. It provides a systematic overview of how PK is linked to PD, introduces the basic concepts of PK-PD modeling and presents the underlying theory behind it, and discusses the specific aspects of PK-PD modeling for various classes of drugs.

Author : L. F. Prescott
Publisher :
ISBN 13 :
Total Pages : 1216 pages
Book Rating : 4.46/5 ( download)

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Download or read book Handbook of Clinical Pharmacokinetics written by L. F. Prescott and published by . This book was released on 1983 with total page 1216 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Author : Wolfgang A. Ritschel
Publisher :
ISBN 13 :
Total Pages : 572 pages
Book Rating : 4.36/5 ( download)

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Download or read book Handbook of Basic Pharmacokinetics-- Including Clinical Applications written by Wolfgang A. Ritschel and published by . This book was released on 1986 with total page 572 pages. Available in PDF, EPUB and Kindle. Book excerpt: