Green Chemistry In The Pharmaceutical Industry

Author : Peter J. Dunn
Publisher : John Wiley & Sons
ISBN 13 : 9783527629695
Total Pages : 388 pages
Book Rating : 4.96/5 ( download)

DOWNLOAD NOW!

Download or read book Green Chemistry in the Pharmaceutical Industry written by Peter J. Dunn and published by John Wiley & Sons. This book was released on 2010-02-02 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: Edited by three of the world's leading pharmaceutical scientists, this is the first book on this important and hot topic, containing much previously unpublished information. As such, it covers all aspects of green chemistry in the pharmaceutical industry, from simple molecules to complex proteins, and from drug discovery to the fate of pharmaceuticals in the environment. Furthermore, this ready reference contains several convincing case studies from industry, such as Taxol, Pregabalin and Crestor, illustrating how this multidisciplinary approach has yielded efficient and environmentally-friendly processes. Finally, a section on technology and tools highlights the advantages of green chemistry.

Author : Stefan Koenig
Publisher : CRC Press
ISBN 13 : 9814364819
Total Pages : 378 pages
Book Rating : 4.12/5 ( download)

DOWNLOAD NOW!

Download or read book Scalable Green Chemistry written by Stefan Koenig and published by CRC Press. This book was released on 2013-09-11 with total page 378 pages. Available in PDF, EPUB and Kindle. Book excerpt: Packed with real-world examples, this book illustrates the 12 principles of green chemistry. These diverse case studies demonstrate to scientists and students that beyond the theory, the challenges of green chemistry in pharmaceutical discovery and development remain an ongoing endeavor. By informing and welcoming additional practitioners to this m

Author : Louise Summerton
Publisher : Royal Society of Chemistry
ISBN 13 : 1782625941
Total Pages : 272 pages
Book Rating : 4.40/5 ( download)

DOWNLOAD NOW!

Download or read book Green and Sustainable Medicinal Chemistry written by Louise Summerton and published by Royal Society of Chemistry. This book was released on 2016-03-08 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pharmaceutical manufacturing was one of the first industries to recognize the importance of green chemistry, with pioneering work including green chemistry metrics and alternative solvents and reagents. Today, other topical factors also have to be taken into consideration, such as rapidly depleting resources, high energy costs and new legislation. This book addresses current challenges in modern green chemical technologies and sustainability thinking. It encompasses a broad range of topics covered by the CHEM21 project – Europe’s largest public-private partnership project which aims to develop a toolbox of sustainable technologies for green chemical intermediate manufacture. Divided into two sections, the book first gives an overview of the key green chemistry tools, guidance and considerations aimed at developing greener processes, before moving on to look at cutting-edge synthetic methodologies. Featuring innovative research, this book is an invaluable reference for chemists across academia and industry wanting to further their knowledge and understanding of this important topic.

Author : Marianna Torok
Publisher : Elsevier
ISBN 13 : 0128232714
Total Pages : 568 pages
Book Rating : 4.12/5 ( download)

DOWNLOAD NOW!

Download or read book Contemporary Chemical Approaches for Green and Sustainable Drugs written by Marianna Torok and published by Elsevier. This book was released on 2022-08-26 with total page 568 pages. Available in PDF, EPUB and Kindle. Book excerpt: Contemporary Chemical Approaches for Green and Sustainable Drugs provides readers with the knowledge they need to integrate sustainable approaches into their work. Sections cover different aspects of green and sustainable drug development from design to disposal, including computer-aided drug design, green resourcing of drugs and drug candidates, an overview of the health concerns of pharmaceutical pollution, and a survey of potential chemical methods for its reduction. Drawing together the knowledge of a global team of experts, this book provides an inclusive overview of the chemical tools and approaches available for minimizing the negative environmental impact of current and newly developed drugs. This will be a useful guide for all academic and industrial researchers across green and sustainable chemistry, medicinal chemistry, environmental chemistry and pharmaceutical science. Provides an integrative overview of the environmental risks of drugs and drug by products to support chemists in pre-emptively addressing these issues Highlights the advantages of computer-aided drug design, green and sustainable sourcing, and novel methods for the production of safer, more effective drugs Presents individual chapters written by renowned experts with diverse backgrounds Reflects research in practice through selected case studies and extensive state-of-the-art reference sections to serve as a starting point in the design of any specialized environmentally-conscious medicinal chemistry project

Author : Paul F. Richardson
Publisher : Humana
ISBN 13 : 9781071615775
Total Pages : 595 pages
Book Rating : 4.77/5 ( download)

DOWNLOAD NOW!

Download or read book Green Chemistry in Drug Discovery written by Paul F. Richardson and published by Humana. This book was released on 2021-10-26 with total page 595 pages. Available in PDF, EPUB and Kindle. Book excerpt: This detailed book highlights several emerging areas in the implementation of green chemistry in medicinal chemistry drug discovery with a specific focus on their application to the expeditious discovery of new biologically active entities. Divided into three sections, the collection explores greener approaches to chemical transformations that are both prevalent and have been highlighted as challenging within the pharmaceutical industry, overall synthetic strategy, as well as the implementation and impact of a range of enabling technologies within medicinal chemistry. As a volume of the Methods in Pharmacology and Toxicology series, chapters provide the kind of key insight that can guide researchers toward greater success in the lab. Authoritative and practical, Green Chemistry in Drug Discovery: From Academia to Industry provides both a fundamental insight into the progress that has been made as well as some of the challenges that still exist for these techniques to be effectively implemented in the drug discovery process in a routine manner.

Author : Rakesh Kumar Sharma
Publisher : Royal Society of Chemistry
ISBN 13 : 1782620508
Total Pages : 194 pages
Book Rating : 4.01/5 ( download)

DOWNLOAD NOW!

Download or read book Hazardous Reagent Substitution written by Rakesh Kumar Sharma and published by Royal Society of Chemistry. This book was released on 2017-11-28 with total page 194 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years, a significant amount of progress has been made using green chemistry in the synthesis of synthetically useful compounds and molecules by replacing hazardous chemicals with greener alternatives. However, there is still room for improvement, especially in the pharmaceutical sector where new drugs are being formulated. This book examines green approaches to overcoming hazardous organic transformations. Summarizing recent developments, the book features a detailed description of some of the high impact active pharmaceutical ingredients that have been developed considering green chemistry approaches. It explores the design, engineering and process development and the calculations to account for waste. The book includes strategies to further advance green approaches in the development of generic pharmaceutical industries and features novel, innovative approaches that promote waste-free organic synthesis. This book is of interest to industrialists working in pharmaceuticals and researchers working in green chemistry.

Author : Wei Zhang
Publisher : John Wiley & Sons
ISBN 13 : 1119288169
Total Pages : 726 pages
Book Rating : 4.69/5 ( download)

DOWNLOAD NOW!

Download or read book Green Techniques for Organic Synthesis and Medicinal Chemistry written by Wei Zhang and published by John Wiley & Sons. This book was released on 2018-03-19 with total page 726 pages. Available in PDF, EPUB and Kindle. Book excerpt: An updated overview of the rapidly developing field of green techniques for organic synthesis and medicinal chemistry Green chemistry remains a high priority in modern organic synthesis and pharmaceutical R&D, with important environmental and economic implications. This book presents comprehensive coverage of green chemistry techniques for organic and medicinal chemistry applications, summarizing the available new technologies, analyzing each technique’s features and green chemistry characteristics, and providing examples to demonstrate applications for green organic synthesis and medicinal chemistry. The extensively revised edition of Green Techniques for Organic Synthesis and Medicinal Chemistry includes 7 entirely new chapters on topics including green chemistry and innovation, green chemistry metrics, green chemistry and biological drugs, and the business case for green chemistry in the generic pharmaceutical industry. It is divided into 4 parts. The first part introduces readers to the concepts of green chemistry and green engineering, global environmental regulations, green analytical chemistry, green solvents, and green chemistry metrics. The other three sections cover green catalysis, green synthetic techniques, and green techniques and strategies in the pharmaceutical industry. Includes more than 30% new and updated material—plus seven brand new chapters Edited by highly regarded experts in the field (Berkeley Cue is one of the fathers of Green Chemistry in Pharma) with backgrounds in academia and industry Brings together a team of international authors from academia, industry, government agencies, and consultancies (including John Warner, one of the founders of the field of Green Chemistry) Green Techniques for Organic Synthesis and Medicinal Chemistry, Second Edition is an essential resource on green chemistry technologies for academic researchers, R&D professionals, and students working in organic chemistry and medicinal chemistry.

Author : Kumar Gadamasetti
Publisher : CRC Press
ISBN 13 : 9780824719814
Total Pages : 514 pages
Book Rating : 4.16/5 ( download)

DOWNLOAD NOW!

Download or read book Process Chemistry in the Pharmaceutical Industry written by Kumar Gadamasetti and published by CRC Press. This book was released on 1999-05-06 with total page 514 pages. Available in PDF, EPUB and Kindle. Book excerpt: Providing guidance for chemists and other scientists entering pharmaceutical discovery and development, this up-to-the-minute reference presents contributions from an international group of nearly 50 renowned researchers—offering a solid grounding in synthetic and physical organic chemistry, and clarifying the roles of various specialties in the development of new drugs. Featuring over 1000 references, tables, and illustrations, Process Chemistry in the Pharmaceutical Industry is sure to find its way to the bookshelves of organic, physical, analytical, process, and medicinal chemists and biochemists; pharmacists; and upper-level undergraduate and graduate students in these disciplines.

Author : Emily A. Peterson
Publisher : Royal Society of Chemistry
ISBN 13 : 1849739617
Total Pages : 338 pages
Book Rating : 4.10/5 ( download)

DOWNLOAD NOW!

Download or read book Green Chemistry Strategies for Drug Discovery written by Emily A. Peterson and published by Royal Society of Chemistry. This book was released on 2015-06-30 with total page 338 pages. Available in PDF, EPUB and Kindle. Book excerpt: The incorporation of Green Chemistry is a relatively new phenomenon in the drug discovery discipline, since the scale that chemists operate on in drug discovery is smaller than those of process and manufacturing chemistry. The necessary metrics are more difficult to obtain in drug discovery due to the diversity of reactions conducted. However, pharmaceutical companies are realizing that incorporation of green chemistry techniques at earlier stages of drug development can speed the development of a drug candidate. Edited by experts who have pioneered green chemistry efforts within their own institutions, this book provides a practical guide for both academic and industrial labs wanting to know where to start with introducing greener approaches for greatest return on investment. The Editors have taken a comprehensive approach to the topic covering the entire drug discovery process from molecule conception, through synthesis, formulation and toxicology with specific examples and case studies where green chemistry strategies have been implemented. Currently employed as well as emerging techniques for performing greener drug discovery chemistry are addressed as well as cutting-edge topics like biologics discovery. Moreover, important surrounding issues such as intellectual property are included. This book will serve as a practical guide for both academic and industrial chemists who work across the breadth of the drug discovery discipline. Ultimately, readers will learn how to incorporate green chemistry strategies into their everyday workflow without slowing down their science.

Author : Derek Walker
Publisher : John Wiley & Sons
ISBN 13 : 0470259507
Total Pages : 424 pages
Book Rating : 4.04/5 ( download)

DOWNLOAD NOW!

Download or read book The Management of Chemical Process Development in the Pharmaceutical Industry written by Derek Walker and published by John Wiley & Sons. This book was released on 2008-03-03 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt: Here is a practical guide that not only presents insights into the organization and management of the disciplines involved in chemical process development but also provides basic knowledge of these disciplines, enabling process development practitioners to recognize and assimilate them in their work. This book illustrates practical considerations through many examples of the successful direction and integration of the activities of chemists, analysts, chemical engineers, and biologists, as well as safety, regulatory, and environmental professionals in productive teams. Moreover, this reference provides guidance on: Directing and carrying out specific tasks and courses of action Making and communicating clear and achievable decisions Solving problems on the spot Managing the administrative aspects of chemical process development The author, Dr. Derek Walker, has directed chemical process development work for four decades, combining firsthand chemical synthesis experience with many other disciplines needed to create chemical processes. You will benefit from his advice and unique insights into: Understanding the workings of matrix organizations Defining missions and creating action plans Developing interdisciplinary approaches to problem solving Holding review meetings, revising goals, and motivating staff Prioritizing programs and responses to emergencies In addition, you'll learn how successful chemists, in collaboration with other disciplines, define the best (green) chemistry for process scale-up, including accommodating FDA requirements in the last process steps and addressing safety and environmental matters early in their work. Case studies provide incisive perspective on these issues. A chapter on recognizing and patenting intellectual property emphasizes the importance of comprehensive literature surveys and understanding invention. A chapter on the future challenges you to think beyond narrow constraints and explore new horizons.