Gene Function Analysis

Author : Michael F. Ochs
Publisher : Springer Science & Business Media
ISBN 13 : 1588297349
Total Pages : 703 pages
Book Rating : 4.41/5 ( download)

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Download or read book Gene Function Analysis written by Michael F. Ochs and published by Springer Science & Business Media. This book was released on 2007-08-23 with total page 703 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the advent of high-throughput technologies following completion of the human genome project and similar projects, the number of genes of interest has expanded and the traditional methods for gene function analysis cannot achieve the throughput necessary for large-scale exploration. This book brings together a number of recently developed techniques for looking at gene function, including computational, biochemical and biological methods and protocols.

Author : Michael F. Ochs
Publisher : Humana
ISBN 13 : 9781493960637
Total Pages : 0 pages
Book Rating : 4.36/5 ( download)

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Download or read book Gene Function Analysis written by Michael F. Ochs and published by Humana. This book was released on 2016-08-24 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The determination of protein function has been a major goal of molecular biology since the founding of the discipline. However, as we learn more about gene function, we discover that the context within which a gene is expressed controls the specific function of that gene. It has become critical to establish the background in which gene function is determined and to perform experiments in multiple applicable backgrounds. In Gene Function Analysis, Second Edition, a number of computational and experimental techniques are presented for identifying not only the function of an individual gene, but also the partners that work with that gene. The theme of data integration runs strongly through the computational techniques, with many focusing on gathering data from different sources and different biomolecular types. Experimental techniques have evolved to determine function in specific tissues and at specific times during development. Written in the successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and easily accessible, Gene Function Analysis, Second Edition seeks to serve both professionals and novices with a growing understanding of the complexity of gene function.

Author : George G. Harrigan
Publisher : Springer Science & Business Media
ISBN 13 : 1461503337
Total Pages : 342 pages
Book Rating : 4.30/5 ( download)

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Download or read book Metabolic Profiling: Its Role in Biomarker Discovery and Gene Function Analysis written by George G. Harrigan and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 342 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is evident that biochemical control is not strictly hierarchical and that intermediary metabolism can contribute to control of regulatory pathways. Metabolic studies are therefore increasingly important in gene function analyses, and an increased interest in metabolites as biomarkers for disease progression or response to therapeutic intervention is also evident in the pharmaceutical industry. This book offers guidelines to currently available technology and bioinformatics and database strategies now being developed. Evidence is presented that metabolic profiling is a valuable addition to genomics and proteomics strategies devoted to drug discovery and development, and that metabolic profiling offers numerous advantages.

Author : F. Farzaneh
Publisher : Garland Science
ISBN 13 : 1000140962
Total Pages : 314 pages
Book Rating : 4.65/5 ( download)

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Download or read book Functional Analysis of the Human Genome written by F. Farzaneh and published by Garland Science. This book was released on 2020-09-10 with total page 314 pages. Available in PDF, EPUB and Kindle. Book excerpt: An excellent review of the relationship between structure and function in the human genome, and a detailed description of some of the important methodologies for unravelling the function of genes and genomic structures.

Author : Wolfgang Schumann (Prof. Dr. rer. nat.)
Publisher : John Wiley & Sons
ISBN 13 :
Total Pages : 404 pages
Book Rating : 4.73/5 ( download)

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Download or read book Functional Analysis of Bacterial Genes written by Wolfgang Schumann (Prof. Dr. rer. nat.) and published by John Wiley & Sons. This book was released on 2001-02-08 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: Functional Analysis of Bacterial Genes: A Practical Manual summarises the principles and the key methods used to analyse the function of genes in bacteria. Written by members of the Bacillus subtilis Functional Analysis Consortium, this book provides a guide to the many approaches for the systematic analysis of gene function. Features include: * In-depth discussion of the theory and application of the methods * A step-by-step practical guide to each method * Experimental examples to indicate expected results * Contact information for suppliers and resource centres Written by internationally recognised authors, Functional Analysis of Bacterial Genes: A Practical Manual will be a valuable resource to researchers and technicians using functional analysis for many bacterial species, whether in the academic departments of microbiology or genetics, the biotechnology, biomedicine or pharmaceutical industries, or other centres of genomics and bioinformatics. "This volume, and the pioneering effort it represents, will be of interest not only to those of us who are specialists in B. subtilis but to all microbiologists and genome scientists who face the formidable task of uncovering the functions of the myriad uncharacterised genes that are emerging from large-scale sequencing." - Richard Losick , The Biological Laboratories, Harvard University, Cambridge, Massachusetts, USA

Author : Christophe Dessimoz
Publisher :
ISBN 13 : 9781013267710
Total Pages : 298 pages
Book Rating : 4.10/5 ( download)

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Download or read book The Gene Ontology Handbook written by Christophe Dessimoz and published by . This book was released on 2020-10-08 with total page 298 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a practical and self-contained overview of the Gene Ontology (GO), the leading project to organize biological knowledge on genes and their products across genomic resources. Written for biologists and bioinformaticians, it covers the state-of-the-art of how GO annotations are made, how they are evaluated, and what sort of analyses can and cannot be done with the GO. In the spirit of the Methods in Molecular Biology book series, there is an emphasis throughout the chapters on providing practical guidance and troubleshooting advice. Authoritative and accessible, The Gene Ontology Handbook serves non-experts as well as seasoned GO users as a thorough guide to this powerful knowledge system. This work was published by Saint Philip Street Press pursuant to a Creative Commons license permitting commercial use. All rights not granted by the work's license are retained by the author or authors.

Author : Eugene V. Koonin
Publisher : Springer Science & Business Media
ISBN 13 : 1475737831
Total Pages : 482 pages
Book Rating : 4.37/5 ( download)

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Download or read book Sequence — Evolution — Function written by Eugene V. Koonin and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 482 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sequence - Evolution - Function is an introduction to the computational approaches that play a critical role in the emerging new branch of biology known as functional genomics. The book provides the reader with an understanding of the principles and approaches of functional genomics and of the potential and limitations of computational and experimental approaches to genome analysis. Sequence - Evolution - Function should help bridge the "digital divide" between biologists and computer scientists, allowing biologists to better grasp the peculiarities of the emerging field of Genome Biology and to learn how to benefit from the enormous amount of sequence data available in the public databases. The book is non-technical with respect to the computer methods for genome analysis and discusses these methods from the user's viewpoint, without addressing mathematical and algorithmic details. Prior practical familiarity with the basic methods for sequence analysis is a major advantage, but a reader without such experience will be able to use the book as an introduction to these methods. This book is perfect for introductory level courses in computational methods for comparative and functional genomics.

Author : Nalini Raghavachari
Publisher : Humana
ISBN 13 : 9781493978335
Total Pages : 0 pages
Book Rating : 4.30/5 ( download)

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Download or read book Gene Expression Analysis written by Nalini Raghavachari and published by Humana. This book was released on 2018-05-17 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides experimental and bioinformatics approaches related to different aspects of gene expression analysis. Divided in three sections chapters detail wet-lab protocols, bioinformatics approaches, single-cell gene expression, highly multiplexed amplicon sequencing, multi-omics techniques, and targeted sequencing. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Gene Expression Analysis: Methods and Protocols aims provide useful information to researchers worldwide.

Author : Quinn Lu
Publisher : Eaton Publishing Company/Biotechniques Books
ISBN 13 :
Total Pages : 302 pages
Book Rating : 4.70/5 ( download)

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Download or read book Cloning and Expression Vectors for Gene Function Analysis written by Quinn Lu and published by Eaton Publishing Company/Biotechniques Books. This book was released on 2001 with total page 302 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Author : Steve Horvath
Publisher : Springer Science & Business Media
ISBN 13 : 144198819X
Total Pages : 433 pages
Book Rating : 4.95/5 ( download)

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Download or read book Weighted Network Analysis written by Steve Horvath and published by Springer Science & Business Media. This book was released on 2011-04-30 with total page 433 pages. Available in PDF, EPUB and Kindle. Book excerpt: High-throughput measurements of gene expression and genetic marker data facilitate systems biologic and systems genetic data analysis strategies. Gene co-expression networks have been used to study a variety of biological systems, bridging the gap from individual genes to biologically or clinically important emergent phenotypes.