Gene Expression and Its Discontents

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Publisher : Springer
ISBN 13 : 9781441914934
Total Pages : 240 pages
Book Rating : 4.35/5 ( download)

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Book Synopsis Gene Expression and Its Discontents by : Rodrick Wallace

Download or read book Gene Expression and Its Discontents written by Rodrick Wallace and published by Springer. This book was released on 2010 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Gene Expression and Its Discontents

Download Gene Expression and Its Discontents PDF Online Free

Author :
Publisher : Springer Science & Business Media
ISBN 13 : 144191482X
Total Pages : 227 pages
Book Rating : 4.28/5 ( download)

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Book Synopsis Gene Expression and Its Discontents by : Rodrick Wallace

Download or read book Gene Expression and Its Discontents written by Rodrick Wallace and published by Springer Science & Business Media. This book was released on 2009-10-30 with total page 227 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gene Expression and its Discontents examines a class of probability models describing how epigenetic context affects gene expression and organismal development, using the asymptotic limit theorems of information theory in a highly formal manner. Taking classic results on spontaneous symmetry breaking abducted from statistical physics in groupoid, rather than group, circumstances, the work suggests that epigenetic information sources act as analogs to a tunable catalyst, directing development into different characteristic pathways according to the structure of external signals. The results have significant implications for epigenetic epidemiology, in particular for understanding how environmental stressors, in a large sense, can induce a broad spectrum of developmental disorders in humans. The authors then apply the perspective to a number of chronic diseases broadly associated with obesity, using data at different scales of observation.

Computational Psychiatry

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Publisher : Springer
ISBN 13 : 3319539108
Total Pages : 236 pages
Book Rating : 4.02/5 ( download)

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Book Synopsis Computational Psychiatry by : Rodrick Wallace

Download or read book Computational Psychiatry written by Rodrick Wallace and published by Springer. This book was released on 2017-04-20 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explores mental disorders from a uniquely evolutionary perspective. Although there have been many attempts to mathematically model neural processes and, to some extent, their dysfunction, there is very little literature that models mental function within a sociocultural, socioeconomic, and environmental context. Addressing this gap in the extant literature, this book explores essential aspects of mental disorders, recognizing the ubiquitous role played by the exaptation of crosstalk between cognitive modules at many different scales and levels of organization, the missing heritability of complex diseases, and cultural epigenetics. Further, it introduces readers to valuable control theory tools that permit the exploration of the environmental induction of neurodevelopmental disorders, as well as the study of the synergism between culture, psychopathology and sleep disorders, offering a distinctively unique resource.

Cognitive Dynamics on Clausewitz Landscapes

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Publisher : Springer Nature
ISBN 13 : 3030264246
Total Pages : 165 pages
Book Rating : 4.46/5 ( download)

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Book Synopsis Cognitive Dynamics on Clausewitz Landscapes by : Rodrick Wallace

Download or read book Cognitive Dynamics on Clausewitz Landscapes written by Rodrick Wallace and published by Springer Nature. This book was released on 2019-08-20 with total page 165 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book applies cutting-edge methods from cognitive and evolutionary theories to develop models of conflict between hierarchically-structured cognitive entities under circumstances of imprecision, uncertainty and stress. Characterized as friction and the fog-of-war by the Prussian military theorist Carl von Clausewitz, such conditions impair institutional cognition in real-time conflict and pose a real and continuing threat to organizations, such as the US military. In a linked collection of formal essays and a mathematical appendix, the book explores different aspects of cognitive and evolutionary process as conducted under the direction of doctrine that acts as a kind of genome for retention of what is learned through Lamarckian evolutionary selection pressures: armies and corporate entities learn from conflict, and incorporate that learning into their ongoing procedures. The book proposes models and policy solutions for strategic competence. A central feature of the book is a formal description of the famous OODA loop of the US military theorist John Boyd in terms of the Data Rate Theorem that links control and information theories. That description is expanded to cover more fully the impact of stochastic fog-of-war effects on tactical and operational scales of conflict. Subsequent chapters examine in more detail the role of doctrine, and the particular effect of embedding culture on cognitive and Lamarckian evolutionary processes associated with conflict on tactical, operational, and strategic scales and levels of organization. A scientifically sophisticated exercise in applied mathematics, history, evolutionary theory, and ecosystem theory, this book will be appropriate for researchers and students interested in defense, security, and international relations, as well as non-academic career professionals in government and industry.

An Ecosystem Approach to Economic Stabilization

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Publisher : Routledge
ISBN 13 : 1317566696
Total Pages : 175 pages
Book Rating : 4.94/5 ( download)

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Book Synopsis An Ecosystem Approach to Economic Stabilization by : Rodrick Wallace

Download or read book An Ecosystem Approach to Economic Stabilization written by Rodrick Wallace and published by Routledge. This book was released on 2015-02-11 with total page 175 pages. Available in PDF, EPUB and Kindle. Book excerpt: The creation of economic institutions that can function well under substantial uncertainties -- Black Swans -- is analogous to the dilemmas confronting our hunter-gatherer forefathers in the face of large-scale ecological unpredictability. The ultimate solution was not the development of a super hunter-gatherer technology that could ride out repeated catastrophe, but rather the invention, in neolithic times, of culturally-adapted 'farmed' ecosystems constructed to maximize food yield and minimize risks of famine. Recent advances in evolutionary and ecosystem theory applied to economic structure and process may permit construction of both new economic theory and new tools for data analysis that can help in the design of more robust economic institutions. This may result in less frequent and less disruptive transitions, and enable the design of culturally-specific systems less affected by those that do occur. This unique and innovative book applies cutting-edge methods from cognitive science and evolutionary theory to the problem of the necessary stabilization of economic processes. At the core of this book is the establishment of a statistics-like toolbox for the study of empirical data that is consistent with generalized evolutionary approaches. This toolbox enables the construction of both new economic theories and methods of data analysis that can help in the design of more robust economic institutions. This in turn will result in less frequent and less disruptive Black Swans, and enable as well the design of culturally-specific systems less affected by those that do occur.

Essays on the Extended Evolutionary Synthesis

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Publisher : Springer Nature
ISBN 13 : 3031298799
Total Pages : 177 pages
Book Rating : 4.90/5 ( download)

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Book Synopsis Essays on the Extended Evolutionary Synthesis by : Rodrick Wallace

Download or read book Essays on the Extended Evolutionary Synthesis written by Rodrick Wallace and published by Springer Nature. This book was released on 2023 with total page 177 pages. Available in PDF, EPUB and Kindle. Book excerpt: From the ‘punctuated equilibrium' of Eldrege and Gould, through Lewontin's ‘triple helix' and the various visions and revisions of the Extended Evolutionary Synthesis (EES) of Laland and others, both data and theory have demanded an opening-up of the 1950's Evolutionary Synthesis that so firmly wedded evolutionary theory to the mathematics of gene frequency analysis. It can, however, be argued that a single deep and comprehensive mathematical theory may simply not be possible for the almost infinite varieties of evolutionary process active at and across the full range of scales of biological, social, institutional, and cultural phenomena. Indeed, the case history of 'meme theory' should have raised a red flag that narrow gene-centered models of evolutionary process may indeed have serious limitations. What is attempted here is less grand, but still broader than a gene-centered analysis. Following the instruction of Maturana and Varela that all living systems are cognitive, in a certain sense, and that living as a process is a process of cognition, the asymptotic limit theorems of information and control theories that bound all cognition provide a basis for constructing an only modestly deep but wider-ranging series of probability models that might be converted into useful statistical tools for the analysis of observational and experimental data related to evolutionary process. The line of argument in this series of interrelated essays proves to be surprisingly direct.

The Mind and Its Discontents

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Publisher : Oxford University Press, USA
ISBN 13 :
Total Pages : 454 pages
Book Rating : 4.37/5 ( download)

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Book Synopsis The Mind and Its Discontents by : Grant Gillett

Download or read book The Mind and Its Discontents written by Grant Gillett and published by Oxford University Press, USA. This book was released on 2009-04-30 with total page 454 pages. Available in PDF, EPUB and Kindle. Book excerpt: The author argues that to understand mental illness fully requires more than a study of biological models of mental processes and pathologies. He stresses that the causes of human mental disorders are to be found in human interactions.

The Philosophy of Biology

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Publisher : Cambridge University Press
ISBN 13 : 9780521643801
Total Pages : 446 pages
Book Rating : 4.05/5 ( download)

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Book Synopsis The Philosophy of Biology by : Marjorie Grene

Download or read book The Philosophy of Biology written by Marjorie Grene and published by Cambridge University Press. This book was released on 2004-08-02 with total page 446 pages. Available in PDF, EPUB and Kindle. Book excerpt: Examines how the philosophy of biology has evolved to our current understanding.

The New Mind-Body Science of Depression

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Publisher : W. W. Norton & Company
ISBN 13 : 0393708608
Total Pages : 640 pages
Book Rating : 4.08/5 ( download)

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Book Synopsis The New Mind-Body Science of Depression by : Vladimir Maletic

Download or read book The New Mind-Body Science of Depression written by Vladimir Maletic and published by W. W. Norton & Company. This book was released on 2017-06-13 with total page 640 pages. Available in PDF, EPUB and Kindle. Book excerpt: The scientific and therapeutic implications of a new way of understanding a common disease. Depression has often been studied, but this multifaceted disease remains far from understood. Here, leading researchers present a major new view of the disorder that synthesizes multiple lines of scientific evidence from neurobiology, mindfulness, and genetics. A comprehensive mind-body approach to understanding, evaluating, and treating this disease.

Transactions on Computational Systems Biology XI

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Publisher : Springer
ISBN 13 : 3642041868
Total Pages : 343 pages
Book Rating : 4.60/5 ( download)

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Book Synopsis Transactions on Computational Systems Biology XI by : Ralph-Johan Back

Download or read book Transactions on Computational Systems Biology XI written by Ralph-Johan Back and published by Springer. This book was released on 2009-10-01 with total page 343 pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue on Computational Models for Cell Processes is based on a workshop that took place in Turku, Finland, May 2008. The papers span a mix of approaches to systems biology, ranging from quantitative techniques to computing paradigms inspired by biology.